| Schedule of Reconciliation of Changes in Intangible Assets |
| | | | | | | | | | | | | | | | | JPY (millions) | | | For the Year Ended March 31 | | | 2025 | | 2026 | | Acquisition cost | | | | | | As of beginning of the year | | ¥ | 5,410,067 | | | ¥ | 5,324,430 | | | | | | | Reclassification to assets held for sale (Note 18) | | (6,999) | | | (11,714) | | | Foreign currency translation differences and others | | (78,637) | | | 496,293 | | | As of end of the year | | ¥ | 5,324,430 | | | ¥ | 5,809,010 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Carrying amount | | | | | | As of beginning of the year | | ¥ | 5,410,067 | | | ¥ | 5,324,430 | | | As of end of the year | | 5,324,430 | | | 5,809,010 | |
| | | | | | | | | | | | | | | | | | | | | | | | | JPY (millions) | | Acquisition cost | Software | | Intangible assets associated with products | | Other | | Total | As of April 1, 2024 | ¥ | 289,116 | | | ¥ | 8,300,433 | | | ¥ | 11,944 | | | ¥ | 8,601,492 | | | Additions and other increases | 38,769 | | | 55,345 | | | 134 | | | 94,248 | | | | | | | | | | | Disposals and other decreases | (4,048) | | | (15,453) | | | (116) | | | (19,617) | | Reclassification to assets held for sale (Note 18) | (95) | | | (11,108) | | | — | | | (11,204) | | | | | | | | | | | Foreign currency translation differences | (4,424) | | | (122,279) | | | (9) | | | (126,712) | | As of March 31, 2025 | ¥ | 319,318 | | | ¥ | 8,206,937 | | | ¥ | 11,953 | | | ¥ | 8,538,208 | | | Additions and other increases | 35,420 | | | 191,426 | | | — | | | 226,845 | | | | | | | | | | | Disposals and other decreases | (15,002) | | | (17,213) | | | (24) | | | (32,238) | | Reclassification to assets held for sale (Note 18) | — | | | (46,943) | | | — | | | (46,943) | | | | | | | | | | | Foreign currency translation differences | 32,307 | | | 640,053 | | | 59 | | | 672,419 | | As of March 31, 2026 | ¥ | 372,043 | | | ¥ | 8,974,261 | | | ¥ | 11,988 | | | ¥ | 9,358,291 | |
| | | | | | | | | | | | | | | | | | | | | | | | Accumulated amortization and accumulated impairment losses | | | | | | | | As of April 1, 2024 | ¥ | (139,483) | | | ¥ | (4,186,707) | | | ¥ | (620) | | | ¥ | (4,326,810) | | | Amortization | (40,414) | | | (548,660) | | | (113) | | | (589,187) | | | Impairment losses | (556) | | | (95,047) | | | — | | | (95,602) | | | | | | | | | | | Disposals and other decreases | 3,081 | | | 15,283 | | | 20 | | | 18,384 | | Reclassification to assets held for sale (Note 18) | 63 | | | 11,108 | | | — | | | 11,171 | | | | | | | | | | | Foreign currency translation differences | 2,538 | | | 72,858 | | | 1 | | | 75,397 | | As of March 31, 2025 | ¥ | (174,771) | | | ¥ | (4,731,164) | | | ¥ | (713) | | | ¥ | (4,906,647) | | | Amortization | (42,544) | | | (504,475) | | | (97) | | | (547,116) | | | Impairment losses | (762) | | | (132,640) | | | — | | | (133,402) | | | | | | | | | | | Disposals and other decreases | 14,987 | | | 17,213 | | | 2 | | | 32,202 | | Reclassification to assets held for sale (Note 18) | — | | | 43,353 | | | — | | | 43,353 | | | | | | | | | | | Foreign currency translation differences | (19,665) | | | (407,643) | | | (25) | | | (427,332) | | As of March 31, 2026 | ¥ | (222,756) | | | ¥ | (5,715,356) | | | ¥ | (832) | | | ¥ | (5,938,943) | |
| | | | | | | | | | | | | | | | | | | | | | | | | Carrying amount | | | | | | | | As of April 1, 2024 | ¥ | 149,632 | | | ¥ | 4,113,726 | | | ¥ | 11,324 | | | ¥ | 4,274,682 | | As of March 31, 2025 | 144,547 | | | 3,475,773 | | | 11,240 | | | 3,631,560 | | As of March 31, 2026 | 149,287 | | | 3,258,905 | | | 11,156 | | | 3,419,348 | |
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| Schedule of Intangible Assets Associated with Products |
The intangible assets associated with products are comprised of the following: | | | | | | | | | | | | | | | | | | | JPY (millions) | | Marketed products | | In-process R&D | | Carrying amount | As of April 1, 2024 | ¥ | 3,148,680 | | | ¥ | 965,045 | | | ¥ | 4,113,726 | | As of March 31, 2025 | 2,556,431 | | | 919,342 | | | 3,475,773 | | As of March 31, 2026 | 2,188,277 | | | 1,070,628 | | | 3,258,905 | |
The table below provides information about significant intangible assets. | | | | | | | | | | | | | | | | | | | | | | | JPY (millions) Carrying amount | | Remaining amortization period | | | As of March 31 | | As of March 31 | | | 2025 | | 2026 | | 2026 | | Immunoglobulins | Marketed products | ¥ | 710,287 | | | ¥ | 682,868 | | | 9 Years | | Zasocitinib (TAK-279) | In-process R&D | 609,329 | | | 652,592 | | | - | | TAKHZYRO | Marketed products | 496,676 | | | 471,297 | | | 8 Years | | ADVATE & ADYNOVATE/ADYNOVI | Marketed products | 220,595 | | | 192,138 | | | 4 Years | | | | | | | | | ALUNBRIG | Marketed products | 163,329 | | | 113,396 | | | 5 Years | | | | | | | |
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