
	JPY (millions)
Acquisition cost	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Land		Construction in progress		Total
As of April 1, 2024	¥	1,679,054	¥	981,944	¥	164,945	¥	105,845	¥	278,689	¥	3,210,478
Additions and other increases	37,969		22,271		10,480		—		154,435		225,155

Transfers	36,236		48,722		13,185		68		(98,211)		—
Disposals and other decreases	(36,322)		(29,931)		(5,668)		(0)		(7,325)		(79,245)
Reclassification to assets held for sale (Note 18)	(22,552)		(15,493)		(346)		(399)		(12)		(38,803)

Foreign currency translation differences	(22,509)		(12,205)		(2,539)		(1,172)		(5,920)		(44,345)
As of March 31, 2025	¥	1,671,876	¥	995,309	¥	180,056	¥	104,342	¥	321,656	¥	3,273,239
Additions and other increases	32,610		24,540		10,636		274		132,007		200,067

Transfers	31,982		49,066		8,640		56		(89,744)		—
Disposals and other decreases	(15,345)		(28,536)		(10,213)		(2,258)		(2,281)		(58,633)
Reclassification to assets held for sale (Note 18)	(3,061)		(7,322)		(1,015)		(43)		(141)		(11,581)

Foreign currency translation differences	118,010		78,813		12,798		6,403		33,392		249,416
As of March 31, 2026	¥	1,836,073	¥	1,111,871	¥	200,903	¥	108,774	¥	394,889	¥	3,652,509


Accumulated depreciation and accumulated impairment losses
As of April 1, 2024	¥	(507,425)	¥	(586,080)	¥	(115,184)	¥	(273)	¥	(11,739)	¥	(1,220,701)
Depreciation expenses	(86,344)		(66,372)		(20,676)		—		—		(173,392)
Impairment losses	(498)		(830)		(116)		—		(3,333)		(4,778)
Disposals and other decreases	19,132		24,985		5,341		—		2,840		52,298
Reclassification to assets held for sale (Note 18)	14,087		11,642		192		47		—		25,968

Foreign currency translation differences	6,892		6,541		1,974		3		166		15,575
As of March 31, 2025	¥	(554,156)	¥	(610,114)	¥	(128,469)	¥	(223)	¥	(12,068)	¥	(1,305,030)
Depreciation expenses	(85,047)		(68,105)		(20,048)		—		—		(173,200)
Impairment losses	(3,230)		(3,809)		(273)		(156)		(8,150)		(15,619)
Disposals and other decreases	11,481		24,989		9,840		—		334		46,645
Reclassification to assets held for sale (Note 18)	1,005		4,945		809		—		—		6,759

Foreign currency translation differences	(36,608)		(43,667)		(9,395)		(83)		(1,672)		(91,425)
As of March 31, 2026	¥	(666,555)	¥	(695,761)	¥	(147,537)	¥	(462)	¥	(21,555)	¥	(1,531,870)


	JPY (millions)
Carrying amount	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Land		Construction in progress		Total
As of April 1, 2024	¥	1,171,629	¥	395,865	¥	49,761	¥	105,572	¥	266,950	¥	1,989,777
As of March 31, 2025	1,117,720		385,195		51,587		104,119		309,589		1,968,209
As of March 31, 2026	1,169,518		416,109		53,366		108,312		373,334		2,120,639


	JPY (millions)
Acquisition cost of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2024	¥	741,898	¥	21,880	¥	211	¥	763,989
Additions and other increases	18,118		6,867		—		24,986
Disposals and other decreases	(32,499)		(4,677)		(110)		(37,286)

Foreign currency translation differences	(10,687)		(795)		(2)		(11,484)
As of March 31, 2025	¥	716,831	¥	23,275	¥	98	¥	740,204
Additions and other increases	18,549		7,331		2		25,882
Disposals and other decreases	(13,115)		(7,719)		(20)		(20,854)

Foreign currency translation differences	48,913		2,634		5		51,552
As of March 31, 2026	¥	771,178	¥	25,521	¥	86	¥	796,785


	JPY (millions)
Accumulated depreciation and accumulated impairment losses of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2024	¥	(220,496)	¥	(9,930)	¥	(160)	¥	(230,586)
Depreciation expenses	(44,571)		(6,065)		(19)		(50,656)

Disposals and other decreases	14,587		3,741		109		18,437

Foreign currency translation differences	3,738		352		2		4,092
As of March 31, 2025	¥	(246,742)	¥	(11,902)	¥	(68)	¥	(258,712)
Depreciation expenses	(43,731)		(6,406)		(15)		(50,151)
Impairment losses	(1,247)		—		—		(1,247)
Disposals and other decreases	10,344		6,016		20		16,380

Foreign currency translation differences	(18,478)		(1,454)		(4)		(19,936)
As of March 31, 2026	¥	(299,853)	¥	(13,744)	¥	(67)	¥	(313,664)


	JPY (millions)
Carrying amount of ROU Assets	Buildings and structures		Machinery and vehicles		Tools, furniture, and fixtures		Total
As of April 1, 2024	¥	521,403	¥	11,950	¥	51	¥	533,403
As of March 31, 2025	470,089		11,373		30		481,492
As of March 31, 2026	471,325		11,777		18		483,120


	JPY (millions) For the Year Ended March 31
	2024		2025		2026
Expense relating to short-term leases	¥	4,312	¥	4,160	¥	3,624
Expense relating to leases of low-value assets that are not short-term leases expenses	887		493		454
Expense relating to variable lease payments	10,954		11,250		12,263
Total expenses not included in lease liabilities	¥	16,152	¥	15,904	¥	16,341
Total cash outflow for leases not included in lease liabilities	¥	16,152	¥	15,904	¥	16,341

The total cash outflow for leases on lease liabilities for the years ended March 31, 2024, 2025 and 2026 was JPY 75,412 million, JPY 69,685 million and JPY 67,138 million, respectively. Also, the total future cash outflow for leases not yet commenced to which Takeda is committed for the year ended March 31, 2026 is JPY 238,283 million.


	JPY (millions) For the Year Ended March 31
	2024		2025		2026
Cost of sales	¥	(6,225)	¥	(1,485)	¥	(3,358)
Selling, general and administrative expenses	—		(34)		(33)
Research and development expenses	(1,307)		(1)		(7,359)
Other operating expenses	(7,923)		(3,257)		(4,869)
Total	¥	(15,454)	¥	(4,778)	¥	(15,619)

Impairment losses for the year ended March 31, 2024 resulted primarily from production facilities, whose recoverable amounts were nil, related to ALOFISEL (for complex Crohn's perianal fistulas) following topline results of the phase 3 ADMIRE-CD Ⅱ trial.