<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:d967f410-c961-4ff9-9299-e56df0d237bc,g:0fe8c559-454d-453d-b588-dc3bcd428143-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="https://xbrl.org/2023/arcrole/summation-item" xlink:type="simple" xlink:href="https://www.xbrl.org/2023/calculation-1.1.xsd#summation-item"/>
  <link:roleRef roleURI="http://www.conmed.com/role/StatementofNetAssetsAvailableforBenefits" xlink:type="simple" xlink:href="cnmd-20260616.xsd#StatementofNetAssetsAvailableforBenefits"/>
  <link:calculationLink xlink:role="http://www.conmed.com/role/StatementofNetAssetsAvailableforBenefits" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_7c443a53-4080-46a2-ae77-0a82480a491f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue_ae3ffd67-aee8-4889-a11a-7e7e3a5a1ea1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_7c443a53-4080-46a2-ae77-0a82480a491f" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue_ae3ffd67-aee8-4889-a11a-7e7e3a5a1ea1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_3068cd47-dc87-42da-90a0-ec0125f48c1d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_7c443a53-4080-46a2-ae77-0a82480a491f" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_3068cd47-dc87-42da-90a0-ec0125f48c1d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.conmed.com/role/StatementofChangesinNetAssetsAvailableforBenefits" xlink:type="simple" xlink:href="cnmd-20260616.xsd#StatementofChangesinNetAssetsAvailableforBenefits"/>
  <link:calculationLink xlink:role="http://www.conmed.com/role/StatementofChangesinNetAssetsAvailableforBenefits" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_6845f079-61c4-4afa-9eb1-7647542516da" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense_90e85391-fe78-411d-a2e0-05a7a5acd284" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_6845f079-61c4-4afa-9eb1-7647542516da" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense_90e85391-fe78-411d-a2e0-05a7a5acd284" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_08a00be7-2f6e-4ee5-a062-713e288e14d5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_6845f079-61c4-4afa-9eb1-7647542516da" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_08a00be7-2f6e-4ee5-a062-713e288e14d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_615fc663-3c25-46bd-a23d-645ee76fc250" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_a0bf4bf7-b8c0-40f2-a227-712f9146270d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_615fc663-3c25-46bd-a23d-645ee76fc250" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_a0bf4bf7-b8c0-40f2-a227-712f9146270d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_cdb0ca47-ef73-4287-b52a-937276bb5a06" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_615fc663-3c25-46bd-a23d-645ee76fc250" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_cdb0ca47-ef73-4287-b52a-937276bb5a06" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_c3a8569a-edf2-4cd1-9468-26bd3117dd81" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_c3a8569a-edf2-4cd1-9468-26bd3117dd81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment_e79c42c7-d2fd-43da-9eb7-5fa9a991413b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment_e79c42c7-d2fd-43da-9eb7-5fa9a991413b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_2bee8beb-e6ce-42eb-91b9-9a052f001e12" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_2bee8beb-e6ce-42eb-91b9-9a052f001e12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContribution_3e4da36f-d5ef-4690-8d2a-381123b75a55" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContribution"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContribution_3e4da36f-d5ef-4690-8d2a-381123b75a55" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_f011d0bb-e5b3-4a5d-b126-b281cbb11509" xlink:href="https://xbrl.fasb.org/us-gaap/2025/ebp/elts/us-gaap-ebp-2025.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_5ddb2e70-7a41-48cb-bfd0-ea2c2c19739c" xlink:to="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_f011d0bb-e5b3-4a5d-b126-b281cbb11509" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.conmed.com/role/EstablishmentandDescriptionofPlanDetails" xlink:type="simple" xlink:href="cnmd-20260616.xsd#EstablishmentandDescriptionofPlanDetails"/>
  <link:calculationLink xlink:role="http://www.conmed.com/role/EstablishmentandDescriptionofPlanDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfLoans_e4d4f9a9-0257-4a09-9a3a-c7ffd6b5011a" xlink:href="cnmd-20260616.xsd#cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfLoans"/>
    <link:loc xlink:type="locator" xlink:label="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfHomeLoans_cafe700a-8e6b-4fb5-bd6f-a131b1481c72" xlink:href="cnmd-20260616.xsd#cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfHomeLoans"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfLoans_e4d4f9a9-0257-4a09-9a3a-c7ffd6b5011a" xlink:to="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfHomeLoans_cafe700a-8e6b-4fb5-bd6f-a131b1481c72" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfGeneralLoans_e4014b21-e913-4a3a-b6e4-86c8ed572994" xlink:href="cnmd-20260616.xsd#cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfGeneralLoans"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfLoans_e4d4f9a9-0257-4a09-9a3a-c7ffd6b5011a" xlink:to="loc_cnmd_EBPNoteReceivableFromParticipantMaximumNumberOfGeneralLoans_e4014b21-e913-4a3a-b6e4-86c8ed572994" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
