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  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel"/>
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  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel"/>
  <link:labelLink xlink:role="http://www.xbrl.org/2003/role/link" xlink:type="extended">
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover_019e4acd-9cb0-7969-957a-13cccf946756_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Rollovers into the Plan</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Participant Contribution, Rollover</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionRollover" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_MaximumMember_019e4acd-9cb0-7470-a8bc-4147c86e092b_terseLabel_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum</link:label>
    <link:label id="lab_srt_MaximumMember_label_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Maximum [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_MaximumMember" xlink:to="lab_srt_MaximumMember" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_LegalEntityAxis_019e4acd-9cb0-7edb-9b38-aa61881e2e3c_terseLabel_en-US" xlink:label="lab_dei_LegalEntityAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Legal Entity [Axis]</link:label>
    <link:label id="lab_dei_LegalEntityAxis_label_en-US" xlink:label="lab_dei_LegalEntityAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Legal Entity [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LegalEntityAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_LegalEntityAxis" xlink:to="lab_dei_LegalEntityAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeMember_019e4acd-9cb0-7e03-b845-f7672c76e3ff_terseLabel_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:label id="lab_srt_RangeMember_label_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeMember" xlink:to="lab_srt_RangeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable_019e4acd-9cb0-7c2c-87bd-d8b38505b940_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_MutualFundMember_019e4acd-9cb0-7203-9124-e05d382bcabd_terseLabel_en-US" xlink:label="lab_us-gaap_MutualFundMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Mutual funds</link:label>
    <link:label id="lab_us-gaap_MutualFundMember_label_en-US" xlink:label="lab_us-gaap_MutualFundMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Mutual Fund [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MutualFundMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MutualFundMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MutualFundMember" xlink:to="lab_us-gaap_MutualFundMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpOtherInvestmentMember_019e4acd-9cb0-7c28-9e03-f0e243e6173d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpOtherInvestmentMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other Investments</link:label>
    <link:label id="lab_us-gaap-ebp_EbpOtherInvestmentMember_label_en-US" xlink:label="lab_us-gaap-ebp_EbpOtherInvestmentMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Other Investment [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpOtherInvestmentMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpOtherInvestmentMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpOtherInvestmentMember" xlink:to="lab_us-gaap-ebp_EbpOtherInvestmentMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventMember_019e4acd-9cb0-795d-bff4-73b1724dc424_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Subsequent Event</link:label>
    <link:label id="lab_us-gaap_SubsequentEventMember_label_en-US" xlink:label="lab_us-gaap_SubsequentEventMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Subsequent Event [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventMember" xlink:to="lab_us-gaap_SubsequentEventMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable_019e4acd-9cb0-7eb2-99ed-10bc54862ca9_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable_019e4acd-9cb0-73c3-a9a8-6d098c825a6a_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPRSCMember_019e4acd-9cb0-7521-b648-4416942adc22_terseLabel_en-US" xlink:label="lab_pfe_EBPRSCMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Pfizer Savings Plan - Retirement Savings Contribution</link:label>
    <link:label id="lab_pfe_EBPRSCMember_label_en-US" xlink:label="lab_pfe_EBPRSCMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, RSC [Member]</link:label>
    <link:label id="lab_pfe_EBPRSCMember_documentation_en-US" xlink:label="lab_pfe_EBPRSCMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, RSC</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPRSCMember" xlink:href="pfe-20260615.xsd#pfe_EBPRSCMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPRSCMember" xlink:to="lab_pfe_EBPRSCMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_019e4acd-9cb0-7f23-9118-7bde8fff2215_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total deductions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember_019e4acd-9cb0-7b28-b07d-f28ede6e49bf_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Self-directed brokerage account</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Self-Directed Brokerage Account [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanSelfDirectedBrokerageAccountMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount_019e4acd-9cb0-7ccf-9e9f-a7edc1bd557a_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum loan amount</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Account, Maximum Borrowing, Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock_019e4acd-9cb0-7615-b479-721ce0c7dfec_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Measurements</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount_019e4acd-9cb0-704a-b30a-ad68e900be90_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Minimum loan amount</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Account, Minimum Borrowing, Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMinimumBorrowingAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable_019e4acd-9cb0-77ea-aee9-55e1677f74b9_terseLabel_en-US" xlink:label="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment management fees payable</link:label>
    <link:label id="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable_label_en-US" xlink:label="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability for Investment Management Fee Payable</link:label>
    <link:label id="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable_documentation_en-US" xlink:label="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Liability for Investment Management Fee Payable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:href="pfe-20260615.xsd#pfe_EBPLiabilityForInvestmentManagementFeePayable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:to="lab_pfe_EBPLiabilityForInvestmentManagementFeePayable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue_019e4acd-9cb0-7129-8c07-55d037f315c5_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total investments, at fair value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Excluding Plan Interest in Master Trust, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentExcludingPlanInterestInMasterTrustFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_SubsequentEventTypeDomain_019e4acd-9cb0-7de5-9394-dca1d8f10b4e_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Subsequent Event Type [Domain]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventTypeDomain_label_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Subsequent Event Type [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SubsequentEventTypeDomain" xlink:to="lab_us-gaap_SubsequentEventTypeDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_019e4acd-9cb0-71c9-a677-f16deff8cb9d_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Level 1</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel1Member" xlink:to="lab_us-gaap_FairValueInputsLevel1Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock_019e4acd-9cb0-7350-bdc3-6b384fbd8cbf_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock_019e4acd-9cb0-76e4-abac-35304faeba09_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment Contracts</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAsset_019e4acd-9cb0-74d7-9218-9a4b10e36903_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total assets</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAsset_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAsset"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract_019e4acd-9cb0-7328-9b22-8435ccbb58c0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Assets</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeAxis_019e4acd-9cb0-77ef-bf5a-cd4465691b82_terseLabel_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:label id="lab_srt_RangeAxis_label_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeAxis" xlink:to="lab_srt_RangeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract_019e4acd-9cb0-7fe9-af15-ea7549b7504e_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment gain</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable_019e4acd-9cb0-7c8d-801a-a17d7dff6629_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan_019e4acd-9cb0-70de-95a5-839b244784d4_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Transfers into the Plan</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Transfer to (from) Plan</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitTransferToFromExternalPlan" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock_019e4acd-9cb0-73fa-8aa4-a945cf9abea6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Payments of Benefits</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Payment to Participant [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanPaymentToParticipantPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiability_019e4acd-9cb0-73cc-b68d-bdb7fdbfe42b_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total liabilities</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiability_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_AmendmentFlag_019e4acd-9cb0-70e9-93ea-f337c6acfdbf_terseLabel_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Amendment Flag</link:label>
    <link:label id="lab_dei_AmendmentFlag_label_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amendment Flag</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_AmendmentFlag" xlink:to="lab_dei_AmendmentFlag" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution_019e4acd-9cb0-79be-ab51-0277acbe343c_negatedTerseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Deemed distributions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Net Asset Available for Benefit, Deemed Distribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitDeemedDistribution" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionVestingPercentage_019e4acd-9cb0-7c7c-8a94-ae34969c77fd_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Employer contribution vesting percentage</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionVestingPercentage_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution Vesting Percentage</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionVestingPercentage_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Company contribution and/ or investment earning percentage vesting to the participant in Company Matching Contributions, Fixed Rate Contributions, Discretionary Profit-Sharing Contributions, Qualified Non-Elective Contributions, and Disability Contributions, upon completion of minimum service period or attainment of maximum vesting age</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionVestingPercentage" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionVestingPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionVestingPercentage" xlink:to="lab_pfe_EBPEmployerContributionVestingPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock_019e4acd-9cb0-7bee-b2dd-eb56c53c7a33_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Basis of Accounting</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Basis of Accounting [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable_019e4acd-9cb0-7405-b80f-a93241a9f389_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale_019e4acd-9cb0-770e-80ad-8c2e019d8fc3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Securities sold</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment Sale, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate_019e4acd-9cb0-785a-b041-4cd68eb52777_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Rate of Interest</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Interest Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentInterestRate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan and Accounting Change [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract_019e4acd-9cb0-7635-b756-325573c78af7_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Receivables</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Receivable [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_RetirementEligibleScenarioAxis_019e4acd-9cb0-7d09-b40b-f8fc435b83d1_terseLabel_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario [Axis]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioAxis_label_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario [Axis]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioAxis_documentation_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioAxis" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_RetirementEligibleScenarioAxis" xlink:href="pfe-20260615.xsd#pfe_RetirementEligibleScenarioAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_RetirementEligibleScenarioAxis" xlink:to="lab_pfe_RetirementEligibleScenarioAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock_019e4acd-9cb0-7ea0-b161-d567a82ff0e6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Schedule of Plan Investments at Fair Value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPSeparateAccountOtherMember_019e4acd-9cb0-7536-bf9a-e2eabb88957c_terseLabel_en-US" xlink:label="lab_pfe_EBPSeparateAccountOtherMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountOtherMember_label_en-US" xlink:label="lab_pfe_EBPSeparateAccountOtherMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Other [Member]</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountOtherMember_documentation_en-US" xlink:label="lab_pfe_EBPSeparateAccountOtherMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Other</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPSeparateAccountOtherMember" xlink:href="pfe-20260615.xsd#pfe_EBPSeparateAccountOtherMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPSeparateAccountOtherMember" xlink:to="lab_pfe_EBPSeparateAccountOtherMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockMember_019e4acd-9cb0-71bf-be50-9cd2516ce9a1_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common Stock</link:label>
    <link:label id="lab_us-gaap_CommonStockMember_label_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockMember" xlink:to="lab_us-gaap_CommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_019e4acd-9cb0-7d2b-9cf3-600556b92846_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments [Domain]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investments [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:to="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_019e4acd-9cb0-7ef0-9641-bbadae98a05a_terseLabel_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Primary residence, loan term</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_label_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Account, Primary Residence, Maximum Borrowing Term</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_documentation_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Account, Primary Residence, Maximum Borrowing Term</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:href="pfe-20260615.xsd#pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:to="lab_pfe_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock_019e4acd-9cb0-7720-aa0b-89fb9d53b4b2_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Use of Estimates</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Use of Estimate [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_ContributionsTrancheTwoMember_019e4acd-9cb0-767e-bda2-dc3d310969e7_terseLabel_en-US" xlink:label="lab_pfe_ContributionsTrancheTwoMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contributions, Tranche Two</link:label>
    <link:label id="lab_pfe_ContributionsTrancheTwoMember_label_en-US" xlink:label="lab_pfe_ContributionsTrancheTwoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contributions, Tranche Two [Member]</link:label>
    <link:label id="lab_pfe_ContributionsTrancheTwoMember_documentation_en-US" xlink:label="lab_pfe_ContributionsTrancheTwoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contributions, Tranche Two</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_ContributionsTrancheTwoMember" xlink:href="pfe-20260615.xsd#pfe_ContributionsTrancheTwoMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_ContributionsTrancheTwoMember" xlink:to="lab_pfe_ContributionsTrancheTwoMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock_019e4acd-9cb0-7f30-a73e-2d4d130925ba_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Schedule H, Line 4i &#8211; Schedule of Assets (Held At End of Year)</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CoverAbstract_label_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cover [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CoverAbstract" xlink:to="lab_dei_CoverAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_InvestmentsAtFairValueMember_019e4acd-9cb0-7567-8331-3c8e63b35d35_terseLabel_en-US" xlink:label="lab_pfe_InvestmentsAtFairValueMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments at Fair Value</link:label>
    <link:label id="lab_pfe_InvestmentsAtFairValueMember_label_en-US" xlink:label="lab_pfe_InvestmentsAtFairValueMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investments at Fair Value [Member]</link:label>
    <link:label id="lab_pfe_InvestmentsAtFairValueMember_documentation_en-US" xlink:label="lab_pfe_InvestmentsAtFairValueMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Investments at Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_InvestmentsAtFairValueMember" xlink:href="pfe-20260615.xsd#pfe_InvestmentsAtFairValueMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_InvestmentsAtFairValueMember" xlink:to="lab_pfe_InvestmentsAtFairValueMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock_019e4acd-9cb0-7895-b98d-db63825d5419_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Risks and Uncertainties</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid_019e4acd-9cb0-76a1-b686-0872cd12960a_negatedTerseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Amounts allocated to withdrawing participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Net Asset Available for Benefit, Allocation to Withdrawing Participant, Not yet Paid</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitAllocationToWithdrawingParticipantNotYetPaid" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash_019e4acd-9cb0-7dc0-b977-584a74aef423_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Company matching contributions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Employer Contribution, Cash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionCash" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_RetirementEligibleScenarioDomain_019e4acd-9cb0-7bf0-9030-ba8b2c5a2bc2_terseLabel_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario [Domain]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioDomain_label_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario [Domain]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioDomain_documentation_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioDomain" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_RetirementEligibleScenarioDomain" xlink:href="pfe-20260615.xsd#pfe_RetirementEligibleScenarioDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_RetirementEligibleScenarioDomain" xlink:to="lab_pfe_RetirementEligibleScenarioDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_MinimumMember_019e4acd-9cb0-70ed-9ab2-d12a8a853c90_terseLabel_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Minimum</link:label>
    <link:label id="lab_srt_MinimumMember_label_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Minimum [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_MinimumMember" xlink:to="lab_srt_MinimumMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable_019e4acd-9cb0-7f3e-8237-c790d30749ed_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest and other</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment Income, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_019e4acd-9cb0-7486-b79b-970e62f0489d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest income from notes receivable from participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Interest Income on Note Receivable from Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_019e4acd-9cb0-73b0-b858-f23885b8a335_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeAxis" xlink:to="lab_us-gaap_InvestmentTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan_019e4acd-9cb0-787f-a95c-1fb6884e83c0_terseLabel_en-US" xlink:label="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant loans transferred to the plan</link:label>
    <link:label id="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan_label_en-US" xlink:label="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Participant Loans, Transfer to (from) Plan</link:label>
    <link:label id="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan_documentation_en-US" xlink:label="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Participant Loans, Transfer to (from) Plan</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:href="pfe-20260615.xsd#pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:to="lab_pfe_EBPChangeInNetAssetAvailableForBenefitParticipantLoansTransferToFromPlan" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution_019e4acd-9cb0-78df-9dd7-5abe71b3a02b_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total contributions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Contribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForContribution" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover_019e4acd-9cb0-7383-8559-5603b07822b4_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Participant Contribution, Excluding Rollover</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod_019e4acd-9cb0-7821-bbdf-87f5ec48fa53_terseLabel_en-US" xlink:label="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant contribution, automatic deferral enrollment period</link:label>
    <link:label id="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod_label_en-US" xlink:label="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Automatic, Deferral Enrollment Period</link:label>
    <link:label id="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod_documentation_en-US" xlink:label="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Automatic, Deferral Enrollment Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:href="pfe-20260615.xsd#pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:to="lab_pfe_EBPParticipantContributionAutomaticDeferralEnrollmentPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_019e4acd-9cb0-7c38-a397-6bd6596a9b26_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net appreciation in investments</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease) from Gain (Loss) on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems_019e4acd-9cb0-7996-9328-6df007f12384_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems_019e4acd-9cb0-741d-9046-5be323095177_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock_019e4acd-9cb0-7cc0-90b8-9b41f214d4b5_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Description of the Plan and Recent Transactions and Events</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPSavingsMember_019e4acd-9cb0-7f17-a2b7-1344a5e11579_terseLabel_en-US" xlink:label="lab_pfe_EBPSavingsMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Pfizer Savings Plan</link:label>
    <link:label id="lab_pfe_EBPSavingsMember_label_en-US" xlink:label="lab_pfe_EBPSavingsMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP Savings [Member]</link:label>
    <link:label id="lab_pfe_EBPSavingsMember_documentation_en-US" xlink:label="lab_pfe_EBPSavingsMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP Savings</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPSavingsMember" xlink:href="pfe-20260615.xsd#pfe_EBPSavingsMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPSavingsMember" xlink:to="lab_pfe_EBPSavingsMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems_019e4acd-9cb0-7b81-892a-916942bd1b9e_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable_019e4acd-9cb0-779b-82c7-11fa64e854e6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod_019e4acd-9cb0-78ec-b67f-632c8d62719d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Adjustment of T. Rowe Price Stable Value Fund from contract value to fair value at beginning of year</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Change in Net Asset Available for Benefit, Prior Period, Increase from Deemed Distribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitIncreaseForDeemedDistributionPriorPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment_019e4acd-9cb0-7e87-9e90-0418cb990868_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Adjustment of T. Rowe Price Stable Value Fund from contract value to fair value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Net Asset Available for Benefit, Contract Value to Current Value Adjustment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500NetAssetAvailableForBenefitContractValueToCurrentValueAdjustment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems_019e4acd-9cb0-73d2-a495-fdc932961f05_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment_019e4acd-9cb0-7572-a7f2-29d8a642228d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest income</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Interest Income on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember_019e4acd-9cb0-7fd5-971f-f456766d3720_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Pfizer Inc. common stock</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer, Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract_019e4acd-9cb0-7151-afd3-40d9b0e624c3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Abstract]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable_019e4acd-9cb0-715f-aada-d3043f2ed518_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Accounting Policy [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Accounting Policy [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_019e4acd-9cb0-7239-9057-735a0826dd11_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total additions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentIdentifierAxis_019e4acd-9cb0-79d7-a59d-0ef2ba897a46_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentIdentifierAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment, Identifier [Axis]</link:label>
    <link:label id="lab_us-gaap_InvestmentIdentifierAxis_label_en-US" xlink:label="lab_us-gaap_InvestmentIdentifierAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investment, Identifier [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIdentifierAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentIdentifierAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentIdentifierAxis" xlink:to="lab_us-gaap_InvestmentIdentifierAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense_019e4acd-9cb0-7625-862c-cef243caa712_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Administrative expenses</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease from Administrative Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment_019e4acd-9cb0-76ec-b0a2-04c0591a9bb7_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestment"/>
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    <link:label id="lab_dei_DocumentInformationLineItems_019e4acd-9cb0-7d9d-a157-ea73f19842f7_terseLabel_en-US" xlink:label="lab_dei_DocumentInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Information [Line Items]</link:label>
    <link:label id="lab_dei_DocumentInformationLineItems_label_en-US" xlink:label="lab_dei_DocumentInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationLineItems" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentInformationLineItems"/>
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    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Line Items]</link:label>
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    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable_019e4acd-9cb0-720b-9e56-f01eb5bfd593_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpRiskAndUncertaintyTable"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionParticipantCompensationMatchedPercentage_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionParticipantCompensationMatchedPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Participant Compensation Matched, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionParticipantCompensationMatchedPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanEmployerContributionParticipantCompensationMatchedPercentage"/>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract"/>
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    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_019e4acd-9cb0-7864-bfce-bf0d752c058c_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Level 2</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value, Inputs, Level 2 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel2Member" xlink:to="lab_us-gaap_FairValueInputsLevel2Member" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionTypeDomain_019e4acd-9cb0-7384-8ec4-5bd9ce14f0df_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type [Domain]</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionTypeDomain_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type [Domain]</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionTypeDomain_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeDomain" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionTypeDomain" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionTypeDomain"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitDecreaseForDeemedDistributionCurrentPeriod_019e4acd-9cb0-774d-a427-4afc3aa616fc_negatedTerseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitDecreaseForDeemedDistributionCurrentPeriod" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Adjustment of T. Rowe Price Stable Value Fund from contract value to fair value at end of year</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitDecreaseForDeemedDistributionCurrentPeriod" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500ChangeInNetAssetAvailableForBenefitDecreaseForDeemedDistributionCurrentPeriod"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss_019e4acd-9cb0-7ef3-9e3d-1c576175cb3d_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net appreciation in investments per Form&#160;5500</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Form 5500 Caption, Net Income (Loss)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetIncomeLoss"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems_019e4acd-9cb0-7491-8f9b-c7483819a653_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_019e4acd-9cb0-762f-928b-be0602229b8c_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Company</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Employer Contribution, Cash and Noncash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution"/>
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    <link:label id="lab_us-gaap_SubsequentEventTypeAxis_019e4acd-9cb0-7caf-aa83-ffb7630ba1ee_terseLabel_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Subsequent Event Type [Axis]</link:label>
    <link:label id="lab_us-gaap_SubsequentEventTypeAxis_label_en-US" xlink:label="lab_us-gaap_SubsequentEventTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Subsequent Event Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventTypeAxis"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable_019e4acd-9cb0-7c5b-8247-bf0aec9aacbb_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_019e4acd-9cb0-77a6-8e69-fa0f01c659b2_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net increase</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock_019e4acd-9cb0-77b7-b556-ebddfec85d13_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Related Party Transactions and Party-In-Interest Transactions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock"/>
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    <link:label id="lab_pfe_EBPSeparateAccountMember_019e4acd-9cb0-752c-b5fd-b2c96faf319f_terseLabel_en-US" xlink:label="lab_pfe_EBPSeparateAccountMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Separate account</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountMember_label_en-US" xlink:label="lab_pfe_EBPSeparateAccountMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Separate Account [Member]</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountMember_documentation_en-US" xlink:label="lab_pfe_EBPSeparateAccountMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Separate Account</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPSeparateAccountMember" xlink:href="pfe-20260615.xsd#pfe_EBPSeparateAccountMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPSeparateAccountMember" xlink:to="lab_pfe_EBPSeparateAccountMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Accounting Policy, Accounting Standard Update, and Change in Accounting Principle [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivable_019e4acd-9cb0-796e-8e9a-a842a68a3f55_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivable" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total receivables</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReceivable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable_019e4acd-9cb0-74f5-913a-ee619c2db453_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Company contributions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate_019e4acd-9cb0-76f4-a123-b3ef2a297018_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant contribution, automatic deferral rate</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Automatic, Deferral Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantContributionAutomaticDeferralRate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract_019e4acd-9cb0-7484-bd5a-598e75b63540_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments, at fair value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_019e4acd-9cb0-7142-9433-5a61ca789329_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Benefits paid to participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease from Payment to Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment_019e4acd-9cb0-7c42-88c1-bb993e7fb0dc_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Dividend income</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Dividend Income on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue_019e4acd-9cb0-7722-b56e-5ff8a357a45d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total investments</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Investment, Excluding Plan Interest in Master Trust, Current Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustCurrentValue" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod_019e4acd-9cb0-7c11-833e-09215023ae46_terseLabel_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Note receivable from participant, termination of employment, repayment period</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod_label_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Termination of Employment, Repayment Period</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod_documentation_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Termination of Employment, Repayment Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:href="pfe-20260615.xsd#pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:to="lab_pfe_EBPNoteReceivableFromParticipantTerminationOfEmploymentRepaymentPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019e4acd-9cb0-7638-bb61-24601d82a355_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_label_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems_019e4acd-9cb0-7e33-8996-063b0ac69446_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Accounting Policy [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Accounting Policy [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAccountingPolicyLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract_019e4acd-9cb0-790e-82b6-3076bb75e4a7_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments, at contract value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Contract Value [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValueAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_ContributionsTrancheOneMember_019e4acd-9cb0-7c83-8d6a-670692332d6f_terseLabel_en-US" xlink:label="lab_pfe_ContributionsTrancheOneMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contributions, Tranche One</link:label>
    <link:label id="lab_pfe_ContributionsTrancheOneMember_label_en-US" xlink:label="lab_pfe_ContributionsTrancheOneMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contributions, Tranche One [Member]</link:label>
    <link:label id="lab_pfe_ContributionsTrancheOneMember_documentation_en-US" xlink:label="lab_pfe_ContributionsTrancheOneMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contributions, Tranche One</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_ContributionsTrancheOneMember" xlink:href="pfe-20260615.xsd#pfe_ContributionsTrancheOneMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_ContributionsTrancheOneMember" xlink:to="lab_pfe_ContributionsTrancheOneMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table_019e4acd-9cb0-7741-9549-12160344a0a5_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Table" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_RetirementEligibleScenarioOneMember_019e4acd-9cb0-7a2c-a451-26143551e939_terseLabel_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioOneMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario One</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioOneMember_label_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioOneMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario One [Member]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioOneMember_documentation_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioOneMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario One</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_RetirementEligibleScenarioOneMember" xlink:href="pfe-20260615.xsd#pfe_RetirementEligibleScenarioOneMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_RetirementEligibleScenarioOneMember" xlink:to="lab_pfe_RetirementEligibleScenarioOneMember" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPMandatorySmallBenefitCashoutAmount_019e4acd-9cb0-79d4-9564-c865300d6e22_terseLabel_en-US" xlink:label="lab_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Mandatory small benefit cashout amount</link:label>
    <link:label id="lab_pfe_EBPMandatorySmallBenefitCashoutAmount_label_en-US" xlink:label="lab_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Mandatory Small Benefit Cashout Amount</link:label>
    <link:label id="lab_pfe_EBPMandatorySmallBenefitCashoutAmount_documentation_en-US" xlink:label="lab_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Mandatory Small Benefit Cashout Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:href="pfe-20260615.xsd#pfe_EBPMandatorySmallBenefitCashoutAmount"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:to="lab_pfe_EBPMandatorySmallBenefitCashoutAmount" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems_019e4acd-9cb0-7040-adef-e5c8b61fed55_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500LineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionVestingServicePeriod_019e4acd-9cb0-79d6-9eb9-f6049498b02f_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingServicePeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Employer contribution vesting service period</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionVestingServicePeriod_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingServicePeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution Vesting Service Period</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionVestingServicePeriod_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionVestingServicePeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution Vesting Service Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionVestingServicePeriod" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionVestingServicePeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionVestingServicePeriod" xlink:to="lab_pfe_EBPEmployerContributionVestingServicePeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate_019e4acd-9cb0-7e91-921a-b08884b217a2_terseLabel_en-US" xlink:label="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Basis spread on variable rate</link:label>
    <link:label id="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate_label_en-US" xlink:label="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Loan, Basis Spread On Variable Rate</link:label>
    <link:label id="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate_documentation_en-US" xlink:label="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Loan, Basis Spread On Variable Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:href="pfe-20260615.xsd#pfe_EBPParticipantLoanBasisSpreadOnVariableRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:to="lab_pfe_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions_019e4acd-9cb0-712f-bea7-5e6659e2cb30_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Eligible age for catch-up contributions</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Eligible Age for Catch-up Contributions</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Eligible Age for Catch-up Contributions</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:to="lab_pfe_EBPEmployerContributionEligibleAgeForCatchUpContributions" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant_019e4acd-9cb0-789e-bfb2-9b0359e4b469_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Benefits paid to participants, including rollovers, per Form&#160;5500</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Form 5500 Caption, Benefit Payment and Payments to Provide Benefits</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionPaymentToParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod_019e4acd-9cb0-724c-92aa-034b864c099b_negatedTerseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Amounts allocated to withdrawing participants and deemed distributions at beginning of year</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Payment to Participant, Prior Period, Decrease from Deemed Distribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantDecreaseForDeemedDistributionPriorPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock_019e4acd-9cb0-76f8-97a2-8648f0ea4b04_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Reconciliation of Financial Statements to Form 5500</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500TextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution_019e4acd-9cb0-7aae-8328-ac4dd73b8ba8_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes receivable from participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Participant Loan, after Deemed Distribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock_019e4acd-9cb0-7072-802c-e48f2feec859_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment Valuation and Income Recognition</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentType_019e4acd-9cb0-7854-8824-194fbf6eb744_terseLabel_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Type</link:label>
    <link:label id="lab_dei_DocumentType_label_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Type</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentType" xlink:to="lab_dei_DocumentType" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock_019e4acd-9cb0-77aa-ba05-63cbe4becdc2_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Plan Termination</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Plan Termination [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanPlanTerminationTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense_019e4acd-9cb0-774f-a65a-e6324b5645db_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total investment gain</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease) from Investment Income (Loss), before Investment Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForInvestmentIncomeLossBeforeInvestmentExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCentralIndexKey_019e4acd-9cb0-743a-b461-96598324dbd2_terseLabel_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:label id="lab_dei_EntityCentralIndexKey_label_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCentralIndexKey" xlink:to="lab_dei_EntityCentralIndexKey" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate_019e4acd-9cb0-7cb4-be21-d00d4154dfa3_verboseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Interest rates</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate_019e4acd-9cb0-74ac-96a5-50dd4d9c7f3f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest Rates</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Participant Loan, Interest Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation of Financial Statement to Form 5500 [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500Abstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense_019e4acd-9cb0-7cf9-bed7-6fc63f740bf7_negatedTerseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Less: Investment management, redemption and loan fees</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease from Investment Expense</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForInvestmentExpense" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember_019e4acd-9cb0-7d96-8b97-9875e65882ff_terseLabel_en-US" xlink:label="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common/collective trust funds</link:label>
    <link:label id="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember_label_en-US" xlink:label="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Common Collective Trust [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:to="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract_019e4acd-9cb0-763a-beb2-b81206834cd0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net assets available for plan benefits</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Net Asset Available for Benefit [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefitAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpRiskAndUncertaintyAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:to="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems_019e4acd-9cb0-7c7a-9aac-12f2893abf1c_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability_019e4acd-9cb0-78b6-91de-761f7bf3ebd0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Payable to Plan Sponsor</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability to Employer</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanEmployerLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpSubsequentEventTable_019e4acd-9cb0-7ce6-b210-717574b7398d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpSubsequentEventTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpSubsequentEventTable_label_en-US" xlink:label="lab_us-gaap-ebp_EbpSubsequentEventTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpSubsequentEventTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpSubsequentEventTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpSubsequentEventTable" xlink:to="lab_us-gaap-ebp_EbpSubsequentEventTable" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionTypeAxis_019e4acd-9cb0-797e-b854-d46ecfacbe95_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type [Axis]</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionTypeAxis_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type [Axis]</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionTypeAxis_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionTypeAxis" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Type</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionTypeAxis" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionTypeAxis" xlink:to="lab_pfe_EBPEmployerContributionTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract_019e4acd-9cb0-754f-91c7-a99790d67590_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Deductions from net assets attributed to:</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution_019e4acd-9cb0-759d-b3fb-1a10dc508f5c_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Reduction of company contributions from forfeitures</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Forfeited Nonvested Account, Decrease from Employer Contribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccountDecreaseForEmployerContribution" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember_019e4acd-9cb0-7653-9bdf-8e08f9096b2c_terseLabel_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common/collective trust funds</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember_label_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Common Collective Trust [Member]</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember_documentation_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Common Collective Trust</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:href="pfe-20260615.xsd#pfe_EBPSeparateAccountCommonCollectiveTrustMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:to="lab_pfe_EBPSeparateAccountCommonCollectiveTrustMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_019e4acd-9cb0-72e1-86c3-3cb0770bc0ae_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes receivable from participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_019e4acd-9cb0-779f-bf3c-5b52dfa69b37_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:to="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock_019e4acd-9cb0-7f5f-aace-0675a2f5f53d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Summary of Significant Accounting Policies</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Summary of Accounting Policy [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityRegistrantName_019e4acd-9cb0-701d-a7c2-8fcf4244d98e_terseLabel_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:label id="lab_dei_EntityRegistrantName_label_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityRegistrantName" xlink:to="lab_dei_EntityRegistrantName" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPSeparateAccountCommonStockMember_019e4acd-9cb0-7ccd-9af8-17fd6f72f86c_terseLabel_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common stock</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountCommonStockMember_label_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Common Stock [Member]</link:label>
    <link:label id="lab_pfe_EBPSeparateAccountCommonStockMember_documentation_en-US" xlink:label="lab_pfe_EBPSeparateAccountCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Separate Account, Common Stock</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPSeparateAccountCommonStockMember" xlink:href="pfe-20260615.xsd#pfe_EBPSeparateAccountCommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPSeparateAccountCommonStockMember" xlink:to="lab_pfe_EBPSeparateAccountCommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpSubsequentEventAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EbpSubsequentEventAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpSubsequentEventAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpSubsequentEventAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpSubsequentEventAbstract" xlink:to="lab_us-gaap-ebp_EbpSubsequentEventAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract_019e4acd-9cb0-7a63-bb67-b3212c1a375b_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Liabilities</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock_019e4acd-9cb0-7c2a-b5e3-b99efedcd624_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Subsequent Events</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanSubsequentEventTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock_019e4acd-9cb0-78da-a7a1-b95b28b01e6e_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Tax Status</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_RetirementEligibleScenarioTwoMember_019e4acd-9cb0-7f2d-b7b2-57fc9b11ef9a_terseLabel_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioTwoMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario Two</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioTwoMember_label_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioTwoMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario Two [Member]</link:label>
    <link:label id="lab_pfe_RetirementEligibleScenarioTwoMember_documentation_en-US" xlink:label="lab_pfe_RetirementEligibleScenarioTwoMember" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Retirement Eligible Scenario Two</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_RetirementEligibleScenarioTwoMember" xlink:href="pfe-20260615.xsd#pfe_RetirementEligibleScenarioTwoMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_RetirementEligibleScenarioTwoMember" xlink:to="lab_pfe_RetirementEligibleScenarioTwoMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage_019e4acd-9cb0-7057-8b1d-92f12015f5c8_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum loan, to total account, percentage</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Account, Maximum Borrowing, to Total Account, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge_019e4acd-9cb0-7a45-979d-a36d5e9b0bb3_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Employer contribution, matching, retirement age</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Matching, Retirement Eligible, Age</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Matching, Retirement Eligible, Age</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionMatchingRetirementEligibleAge"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:to="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleAge" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPParticipantContributionsVestingPercentage_019e4acd-9cb0-715f-beeb-6354556bab11_terseLabel_en-US" xlink:label="lab_pfe_EBPParticipantContributionsVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant contributions vesting percentage</link:label>
    <link:label id="lab_pfe_EBPParticipantContributionsVestingPercentage_label_en-US" xlink:label="lab_pfe_EBPParticipantContributionsVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Contributions Vesting Percentage</link:label>
    <link:label id="lab_pfe_EBPParticipantContributionsVestingPercentage_documentation_en-US" xlink:label="lab_pfe_EBPParticipantContributionsVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Contributions Vesting Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPParticipantContributionsVestingPercentage" xlink:href="pfe-20260615.xsd#pfe_EBPParticipantContributionsVestingPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPParticipantContributionsVestingPercentage" xlink:to="lab_pfe_EBPParticipantContributionsVestingPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpSubsequentEventLineItems_019e4acd-9cb0-708f-b724-881a7542baa0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpSubsequentEventLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpSubsequentEventLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EbpSubsequentEventLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Subsequent Event [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpSubsequentEventLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpSubsequentEventLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpSubsequentEventLineItems" xlink:to="lab_us-gaap-ebp_EbpSubsequentEventLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm_019e4acd-9cb0-7d7c-b0f1-598cf17a2990_terseLabel_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">General loan, loan term</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm_label_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, General Loan, Maximum Borrowing Term</link:label>
    <link:label id="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm_documentation_en-US" xlink:label="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, General Loan, Maximum Borrowing Term</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:href="pfe-20260615.xsd#pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:to="lab_pfe_EBPNoteReceivableFromParticipantGeneralLoanMaximumBorrowingTerm" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentInformationTable_019e4acd-9cb0-7f9d-a452-7224b3b43eb4_terseLabel_en-US" xlink:label="lab_dei_DocumentInformationTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Information [Table]</link:label>
    <link:label id="lab_dei_DocumentInformationTable_label_en-US" xlink:label="lab_dei_DocumentInformationTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationTable" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentInformationTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentInformationTable" xlink:to="lab_dei_DocumentInformationTable" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService_019e4acd-9cb0-7f36-8438-83e846239e59_terseLabel_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Retirement eligible, minimum years of service</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService_label_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Matching, Retirement Eligible, Minimum Years of Service</link:label>
    <link:label id="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService_documentation_en-US" xlink:label="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Matching, Retirement Eligible, Minimum Years of Service</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:href="pfe-20260615.xsd#pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:to="lab_pfe_EBPEmployerContributionMatchingRetirementEligibleMinimumYearsOfService" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock_019e4acd-9cb0-7a41-a5f1-4f9f9b055fee_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes Receivable from Participants</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment_019e4acd-9cb0-7657-ad73-3af6183aa241_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net investment and interest gain</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease) from Income (Loss) on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_pfe_EBPInvestmentCreditingRateMinimum_019e4acd-9cb0-7e1e-838a-e2c041903600_terseLabel_en-US" xlink:label="lab_pfe_EBPInvestmentCreditingRateMinimum" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Minimum crediting rate</link:label>
    <link:label id="lab_pfe_EBPInvestmentCreditingRateMinimum_label_en-US" xlink:label="lab_pfe_EBPInvestmentCreditingRateMinimum" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Crediting Rate, Minimum</link:label>
    <link:label id="lab_pfe_EBPInvestmentCreditingRateMinimum_documentation_en-US" xlink:label="lab_pfe_EBPInvestmentCreditingRateMinimum" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Investment, Crediting Rate, Minimum</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_pfe_EBPInvestmentCreditingRateMinimum" xlink:href="pfe-20260615.xsd#pfe_EBPInvestmentCreditingRateMinimum"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_pfe_EBPInvestmentCreditingRateMinimum" xlink:to="lab_pfe_EBPInvestmentCreditingRateMinimum" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid_019e4acd-9cb0-72ab-9861-ea5772d8a3aa_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Benefits paid to participants, including rollovers, per the financial statements</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reconciliation to Form 5500, Payment to Participant, Increase from Allocation to Withdrawing Participant, Not yet Paid</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReconciliationToForm5500PaymentToParticipantIncreaseForAllocationToWithdrawingParticipantNotYetPaid" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems_019e4acd-9cb0-7c00-9f51-c412bf3b25b0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Line Items]</link:label>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccount_019e4acd-9cb0-78fb-98a0-121ca94693d5_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForfeitedNonvestedAccount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Forfeitures</link:label>
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    <link:label id="lab_pfe_EBPAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustFairValueAdjustmentToContractValue_019e4acd-9cb0-7884-a5f0-c1138f239ec3_terseLabel_en-US" xlink:label="lab_pfe_EBPAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustFairValueAdjustmentToContractValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total T. Rowe Price Stable Value Fund</link:label>
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    <link:label id="lab_pfe_EBPAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustFairValueAdjustmentToContractValue_documentation_en-US" xlink:label="lab_pfe_EBPAssetHeldForInvestmentInvestmentExcludingPlanInterestInMasterTrustFairValueAdjustmentToContractValue" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Investment, Excluding Plan Interest in Master Trust, Fair Value Adjustment to Contract Value</link:label>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetAssetAvailableForBenefit_019e4acd-9cb0-70e7-80e3-8684d0d545d9_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanForm5500CaptionNetAssetAvailableForBenefit" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net assets available for plan benefits per Form&#160;5500</link:label>
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