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  <xs:element name="GainLossOnSettlementOfConvertibleNotesPayable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_GainLossOnSettlementOfConvertibleNotesPayable"/>
  <xs:element name="UnrealizedLossgainOnEquityInvestments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_UnrealizedLossgainOnEquityInvestments"/>
  <xs:element name="UnrealizedGainOnConvertibleNotesReceivableDueFromCyclo" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_UnrealizedGainOnConvertibleNotesReceivableDueFromCyclo"/>
  <xs:element name="IncreaseDecreaseInConvertibleNotesPayable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_IncreaseDecreaseInConvertibleNotesPayable"/>
  <xs:element name="PurchaseOfPreferredSharesAndWarrantsFromNinaMedical" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_PurchaseOfPreferredSharesAndWarrantsFromNinaMedical"/>
  <xs:element name="ProceedsFromTheSaleAndMaturitiesOfAvailableforsaleSecurities" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ProceedsFromTheSaleAndMaturitiesOfAvailableforsaleSecurities"/>
  <xs:element name="IssuanceOfConvertibleNotesDueFromCyclo" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_IssuanceOfConvertibleNotesDueFromCyclo"/>
  <xs:element name="CashPaidToSettleConvertibleNotesPayable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_CashPaidToSettleConvertibleNotesPayable"/>
  <xs:element name="FairValueOfClassBCommonStockIssuedAsConsiderationInCycloMerger" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfClassBCommonStockIssuedAsConsiderationInCycloMerger"/>
  <xs:element name="FairValueOfRolloverOptionsIssuedAsConsiderationInCycloMerger" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfRolloverOptionsIssuedAsConsiderationInCycloMerger"/>
  <xs:element name="FairValueOfReplacementWarrantsIssuedAsConsiderationInCycloMerger" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfReplacementWarrantsIssuedAsConsiderationInCycloMerger"/>
  <xs:element name="FairValueOfCycloConvertibleNotesReceivableIncludedAsConsiderationInCycloMerger" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfCycloConvertibleNotesReceivableIncludedAsConsiderationInCycloMerger"/>
  <xs:element name="WithdrawalReceivableFromHedgeFundsIncludedInOtherCurrentAssets" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_WithdrawalReceivableFromHedgeFundsIncludedInOtherCurrentAssets"/>
  <xs:element name="ConvertibleNoteReceivableReceivedInExchangeForDayThreeLabsManufacturingAssets" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ConvertibleNoteReceivableReceivedInExchangeForDayThreeLabsManufacturingAssets"/>
  <xs:element name="CycloMergerTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_CycloMergerTextBlock"/>
  <xs:element name="ConvertibleNotesReceivableDueFromCycloTherapeuticsLlcTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ConvertibleNotesReceivableDueFromCycloTherapeuticsLlcTextBlock"/>
  <xs:element name="IntercompanyLineOfCreditTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_IntercompanyLineOfCreditTextBlock"/>
  <xs:element name="ConvertibleNoteReceivableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ConvertibleNoteReceivableTextBlock"/>
  <xs:element name="LiquidityPolicyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_LiquidityPolicyPolicyTextBlock"/>
  <xs:element name="PrepaidClinicalExpensePolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PrepaidClinicalExpensePolicyTextBlock"/>
  <xs:element name="ConvertibleNoteReceivableRelatedPartyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ConvertibleNoteReceivableRelatedPartyPolicyTextBlock"/>
  <xs:element name="InvestmentsHedgeFundPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_InvestmentsHedgeFundPolicyTextBlock"/>
  <xs:element name="CorporateBondsAndUSTreasuryBillsPolicyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_CorporateBondsAndUSTreasuryBillsPolicyPolicyTextBlock"/>
  <xs:element name="InProcessResearchAndDevelopmentPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_InProcessResearchAndDevelopmentPolicyTextBlock"/>
  <xs:element name="ClinicalTrialAccrualsPolicyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ClinicalTrialAccrualsPolicyPolicyTextBlock"/>
  <xs:element name="WarrantsPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_WarrantsPolicyTextBlock"/>
  <xs:element name="ScheduleOfEstimatedUsefulLivesOfLongLivedAssetsTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ScheduleOfEstimatedUsefulLivesOfLongLivedAssetsTableTextBlock"/>
  <xs:element name="ScheduleOfInProcessResearchAndDevelopmentTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ScheduleOfInProcessResearchAndDevelopmentTableTextBlock"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesScheduleofEstimatedUsefulLivesofLongLivedAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_SummaryofSignificantAccountingPoliciesScheduleofEstimatedUsefulLivesofLongLivedAssetsDetailsTable"/>
  <xs:element name="FairValueOfNoncontrollingInterests" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfNoncontrollingInterests"/>
  <xs:element name="FairValueOfPreviouslyHeldEquityInterests" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FairValueOfPreviouslyHeldEquityInterests"/>
  <xs:element name="CycloMergerScheduleofIdentifiableAssetsAcquiredandLiabilitiesAssumedandGoodwillRecognizedDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_CycloMergerScheduleofIdentifiableAssetsAcquiredandLiabilitiesAssumedandGoodwillRecognizedDetailsTable"/>
  <xs:element name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherReceivable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherReceivable"/>
  <xs:element name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedExpenses"/>
  <xs:element name="AccruedClinicalTrialExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_AccruedClinicalTrialExpense"/>
  <xs:element name="FairValueMeasurementsScheduleofAssetsRequiredtobeMeasuredatFairValueonaRecurringBasisDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_FairValueMeasurementsScheduleofAssetsRequiredtobeMeasuredatFairValueonaRecurringBasisDetailsTable"/>
  <xs:element name="WithdrawalFromHedgeFundInvestment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_WithdrawalFromHedgeFundInvestment"/>
  <xs:element name="UnrealizedLossOnCycloWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_UnrealizedLossOnCycloWarrants"/>
  <xs:element name="FundingOfCycloConvertibleNoteV" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_FundingOfCycloConvertibleNoteV"/>
  <xs:element name="ForgivenessOfCycloConvertibleNotesInTheCycloMerger" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ForgivenessOfCycloConvertibleNotesInTheCycloMerger"/>
  <xs:element name="ConversionOfCycloConvertibleNote" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ConversionOfCycloConvertibleNote"/>
  <xs:element name="IssuanceOfNewConvertibleNotesReceivable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_IssuanceOfNewConvertibleNotesReceivable"/>
  <xs:element name="ChangeInFairValueOfConvertibleNotesReceivableClassifiedAsAvailableforSale" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ChangeInFairValueOfConvertibleNotesReceivableClassifiedAsAvailableforSale"/>
  <xs:element name="BusinessSegmentInformationScheduleofOperatingResultsfortheBusinessSegmentsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_BusinessSegmentInformationScheduleofOperatingResultsfortheBusinessSegmentsDetailsTable"/>
  <xs:element name="BusinessSegmentInformationScheduleofOperatingResultsfortheBusinessSegmentsDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_BusinessSegmentInformationScheduleofOperatingResultsfortheBusinessSegmentsDetailsLineItems"/>
  <xs:element name="BusinessSegmentInformationScheduleofReconciliationofOperationsbyReportableSegmentDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_BusinessSegmentInformationScheduleofReconciliationofOperationsbyReportableSegmentDetailsTable"/>
  <xs:element name="BusinessSegmentInformationScheduleofNetPropertyPlantandEquipmentDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_BusinessSegmentInformationScheduleofNetPropertyPlantandEquipmentDetailsTable"/>
  <xs:element name="EquityScheduleofStockOptionActivityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_EquityScheduleofStockOptionActivityDetailsTable"/>
  <xs:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsWeightedAverageRemainigContractualTermGranted" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsWeightedAverageRemainigContractualTermGranted"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardGrantedIntrinsicValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ShareBasedCompensationArrangementByShareBasedPaymentAwardGrantedIntrinsicValue"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardForfeitedlIntrinsicValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ShareBasedCompensationArrangementByShareBasedPaymentAwardForfeitedlIntrinsicValue"/>
  <xs:element name="EquityScheduleofGrantsofRestrictedSharesofClassBCommonStockDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_EquityScheduleofGrantsofRestrictedSharesofClassBCommonStockDetailsTable"/>
  <xs:element name="DescriptionofBusinessDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_DescriptionofBusinessDetailsTable"/>
  <xs:element name="IssuedAndOutstandingOrdinarySharesPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_IssuedAndOutstandingOrdinarySharesPercentage"/>
  <xs:element name="SummaryofSignificantAccountingPoliciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_SummaryofSignificantAccountingPoliciesDetailsTable"/>
  <xs:element name="CycloMergerDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_CycloMergerDetailsTable"/>
  <xs:element name="SharesIssuedInConnectionWithCycloMerger" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_SharesIssuedInConnectionWithCycloMerger"/>
  <xs:element name="ExchangesRatioWithCycloMerger" type="xbrli:decimalItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_ExchangesRatioWithCycloMerger"/>
  <xs:element name="SharesIssuedInConnectionWithRafael" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_SharesIssuedInConnectionWithRafael"/>
  <xs:element name="SharesIssuedPriceInConnectionWithRafael" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_SharesIssuedPriceInConnectionWithRafael"/>
  <xs:element name="SharesIssuedPriceInConnectionWithCycloMerger" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_SharesIssuedPriceInConnectionWithCycloMerger"/>
  <xs:element name="IndefiniteLivedIntangibleAssetUsefulLives" type="xbrli:durationItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="rfl_IndefiniteLivedIntangibleAssetUsefulLives"/>
  <xs:element name="InvestmentinCycloTherapeuticsLLCDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_InvestmentinCycloTherapeuticsLLCDetailsTable"/>
  <xs:element name="OutstandingPrincipalAndAccruedInterest" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_OutstandingPrincipalAndAccruedInterest"/>
  <xs:element name="UnrealizedLossInEquityInvestmentsCycloTherapeuticsInc" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_UnrealizedLossInEquityInvestmentsCycloTherapeuticsInc"/>
  <xs:element name="ConvertibleNotesReceivableDuefromCycloTherapeuticsLLCDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_ConvertibleNotesReceivableDuefromCycloTherapeuticsLLCDetailsTable"/>
  <xs:element name="IntercompanyLineofCreditDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_IntercompanyLineofCreditDetailsTable"/>
  <xs:element name="ConvertibleNotesPayableDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_ConvertibleNotesPayableDetailsTable"/>
  <xs:element name="GainOnSettlementOnDebt" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_GainOnSettlementOnDebt"/>
  <xs:element name="AccruedExpensesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_AccruedExpensesDetailsTable"/>
  <xs:element name="ConvertibleNotesReceivableDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_ConvertibleNotesReceivableDetailsTable"/>
  <xs:element name="MembershipOfferingUnitPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="rfl_MembershipOfferingUnitPercentage"/>
  <xs:element name="PropertyandEquipmentDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_PropertyandEquipmentDetailsTable"/>
  <xs:element name="GoodwillandIntangibleAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_GoodwillandIntangibleAssetsDetailsTable"/>
  <xs:element name="RelatedPartyTransactionsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_RelatedPartyTransactionsDetailsTable"/>
  <xs:element name="RentAndParkingExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_RentAndParkingExpenses"/>
  <xs:element name="PercentageOfRevenue" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfRevenue"/>
  <xs:element name="RightsOffering" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_RightsOffering"/>
  <xs:element name="SubscriptionPricePerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="rfl_SubscriptionPricePerShare"/>
  <xs:element name="AgreementProvidedDays" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_AgreementProvidedDays"/>
  <xs:element name="PercentageOfSharesIssued" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfSharesIssued"/>
  <xs:element name="CombinedVotingPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_CombinedVotingPercentage"/>
  <xs:element name="PercentageOfSharesOutstanding" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfSharesOutstanding"/>
  <xs:element name="InvestmentsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_InvestmentsPercentage"/>
  <xs:element name="PercentageOfFavorableDiscountToFinancingCosts" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfFavorableDiscountToFinancingCosts"/>
  <xs:element name="NetOperatingLossCarryforwards" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_NetOperatingLossCarryforwards"/>
  <xs:element name="BusinessSegmentInformationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_BusinessSegmentInformationDetailsTable"/>
  <xs:element name="NumberOfReportableSegmentsNotDisclosedFlag" type="xbrli:booleanItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_NumberOfReportableSegmentsNotDisclosedFlag"/>
  <xs:element name="CommitmentsandContingenciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="rfl_CommitmentsandContingenciesDetailsTable"/>
  <xs:element name="LicenseIssuanceFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="rfl_LicenseIssuanceFee"/>
  <xs:element name="ReimbursementOfIssuanceFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_ReimbursementOfIssuanceFee"/>
  <xs:element name="PercentageOfNetSale" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfNetSale"/>
  <xs:element name="PercentageOfSublicenseIncome" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_PercentageOfSublicenseIncome"/>
  <xs:element name="MilestonePayments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_MilestonePayments"/>
  <xs:element name="EscalationAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="rfl_EscalationAmount"/>
  <xs:element name="TerminationOfTheLicenseAgreement" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_TerminationOfTheLicenseAgreement"/>
  <xs:element name="BreachOfLicenseAgreement" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="rfl_BreachOfLicenseAgreement"/>
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