1001 - Document - Cover Page link:presentationLink link:definitionLink link:calculationLink 1002 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:definitionLink link:calculationLink 1003 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:definitionLink link:calculationLink 1004 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss link:presentationLink link:definitionLink link:calculationLink 1005 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:definitionLink link:calculationLink 1006 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:definitionLink link:calculationLink 1007 - Disclosure - Nature of Business link:presentationLink link:definitionLink link:calculationLink 1008 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:definitionLink link:calculationLink 1009 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:definitionLink link:calculationLink 1010 - Disclosure - Other Investment link:presentationLink link:definitionLink link:calculationLink 1011 - Disclosure - Accrued Expenses and Other Current Liabilities link:presentationLink link:definitionLink link:calculationLink 1012 - Disclosure - Commitments and Contingencies link:presentationLink link:definitionLink link:calculationLink 1013 - Disclosure - Share-based Compensation Plans link:presentationLink link:definitionLink link:calculationLink 1014 - Disclosure - Loss per share link:presentationLink link:definitionLink link:calculationLink 1015 - Disclosure - Income Taxes link:presentationLink link:definitionLink link:calculationLink 1016 - Disclosure - Defined Contribution Plan link:presentationLink link:definitionLink link:calculationLink 1017 - Disclosure - License and Option Agreement link:presentationLink link:definitionLink link:calculationLink 1018 - Disclosure - Subsequent Events link:presentationLink link:definitionLink link:calculationLink 1019 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:definitionLink link:calculationLink 1020 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:definitionLink link:calculationLink 1021 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables) link:presentationLink link:definitionLink link:calculationLink 1022 - Disclosure - Share-based Compensation Plans (Tables) link:presentationLink link:definitionLink link:calculationLink 1023 - Disclosure - Loss per share (Tables) link:presentationLink link:definitionLink link:calculationLink 1024 - Disclosure - Income Taxes (Tables) link:presentationLink link:definitionLink link:calculationLink 1025 - Disclosure - Nature of Business (Details) link:presentationLink link:definitionLink link:calculationLink 1026 - Disclosure - Summary of Significant Accounting Policies - Revenue, Patent Costs, and Interest and Other Income (Details) link:presentationLink link:definitionLink link:calculationLink 1027 - Disclosure - Summary of Significant Accounting Policies - Income Taxes (Details) link:presentationLink link:definitionLink link:calculationLink 1028 - Disclosure - Fair Value of Financial Instruments (Details) link:presentationLink link:definitionLink link:calculationLink 1029 - Disclosure - Other Investment - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1030 - Disclosure - Accrued Expenses and Other Current Liabilities (Details) link:presentationLink link:definitionLink link:calculationLink 1031 - Disclosure - Commitments and Contingencies - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1032 - Disclosure - Share-based Compensation Plans (Details) link:presentationLink link:definitionLink link:calculationLink 1033 - Disclosure - Share-based Compensation Plans - Schedule of Share-based Compensation Expense (Details) link:presentationLink link:definitionLink link:calculationLink 1034 - Disclosure - Share-based Compensation Plans - Schedule of Stock Option Activity (Details) link:presentationLink link:definitionLink link:calculationLink 1035 - Disclosure - Share-based Compensation Plans - Schedule of Weighted Average Assumptions used in estimating the fair value of the stock options (Details) link:presentationLink link:definitionLink link:calculationLink 1036 - Disclosure - Share-based Compensation Plans - Summary of RSA activity (Details) link:presentationLink link:definitionLink link:calculationLink 1037 - Disclosure - Loss per share - Schedule of Basic and Diluted Net Loss Per Common Share (Details) link:presentationLink link:definitionLink link:calculationLink 1038 - Disclosure - Loss per share - Schedule Of Earnings Per Share Diluted By Common Class (Details) link:presentationLink link:definitionLink link:calculationLink 1039 - Disclosure - Income Taxes - Schedule of Components of Net Income Loss Before Income Tax Expense (Details) link:presentationLink link:definitionLink link:calculationLink 1040 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1041 - Disclosure - Income Taxes - Reconciliation of income taxes (Details) link:presentationLink link:definitionLink link:calculationLink 1042 - Disclosure - Income Taxes - Deferred tax assets (liabilities) (Details) link:presentationLink link:definitionLink link:calculationLink 1043 - Disclosure - Defined Contribution Plan (Details) link:presentationLink link:definitionLink link:calculationLink 1044 - Disclosure - License and Option Agreement - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1045 - Disclosure - Subsequent Events (Additional Information) (Details) link:presentationLink link:definitionLink link:calculationLink Cover [Abstract] Document Information [Table] Document Information, Document [Axis] Document [Domain] Document Information [Line Items] Entity Registrant Name Entity Registrant Name Document Type Document Type Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Central Index Key Entity Central Index Key Amendment Flag Amendment Flag Entity Tax Identification Number Entity Tax Identification Number Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Address, Address Line One Entity Address, Address Line One Entity Address, City or Town Entity Address, City or Town Entity Address, State or Province Entity Address, State or Province Entity Address, Postal Zip Code Entity Address, Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Entity Primary SIC Number Contact Personnel Name Entity Addresses, Address Type [Axis] Address Type [Domain] Business Contact [Member] Statement of Financial Position [Abstract] Assets [Abstract] ASSETS Assets, Current [Abstract] Current assets: Cash and Cash Equivalent Cash and cash equivalents Accounts Receivable, after Allowance for Credit Loss, Current Accounts receivable Prepaid Expense, Current Prepaid expenses Other Assets, Current Other current assets Assets, Current Total current assets Other Long-Term Investments Other investment Assets Total assets Property, Plant and Equipment, Net Property and equipment, net Liabilities and Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Research And Development Current Accrued research and development costs Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development. Used to reflect the current portion of liabilities. Accrued Expenses And Other Liabilities Current Accrued expenses and other current liabilities Accrued expenses and other current liabilities Amount of accrued expenses and other liabilities current. Liabilities, Current Total current liabilities Commitments and Contingencies Commitments and contingencies (Note 6) Equity, Attributable to Parent [Abstract] Stockholders' equity Preferred Stock, Value, Issued Preferred stock, no par value, 100,000,000 shares authorized and 351,037 shares of Series A convertible preferred stock issued and outstanding at March 31, 2026 and December 31, 2025 Common Stock, Value, Issued Common stock, no par value, 400,000,000 shares authorized at March 31, 2026 and December 31, 2025; 4,330,314 and 3,925,314 shares issued at March 31, 2026 and December 31, 2025, respectively; 4,241,260 and 3,821,236 shares outstanding at March 31, 2026 and December 31, 2025, respectively Additional Paid in Capital, Common Stock Paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Statement [Table] Statement [Table] Class of Stock [Axis] Class of Stock [Domain] Series A Convertible Preferred Stock [Member] SeriesA convertible preferred stock. Statement [Line Items] Statement [Line Items] Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shared outstanding Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Beginning balance (in shares) Ending balance (in shares) Income Statement [Abstract] Product and Service [Axis] Product and Service [Domain] License Agreement [Member] Revenue from license agreement License Agreement [Member] Purchase Agreement [Member] Revenue from purchase agreement Purchase agreement. Option Agreement [Member] Revenue from option agreement Option Agreement. Revenues: Revenues Total revenues Revenues Operating Expenses [Abstract] Cost and expenses: Research and Development Expense Research and development Research and development expense General and Administrative Expense General and administrative Operating Expenses Total cost and expenses Operating expenses Nonoperating Income (Expense) Total other income, net Operating Income (Loss) Loss from operations Nonoperating Income (Expense) [Abstract] Other income, net Other Nonoperating Income Interest income Gain Loss from Settlement of Account Payable Gain from settlement of account payable Gain from settlement of account payable Gain (loss) from settlement of account payable. Gain on Business Interruption Insurance Recovery Gain from insurance recovery Net loss Net loss Net loss Earnings Per Share [Abstract] Net loss per share: Earnings Per Share, Basic Net loss per share - Basic Earnings Per Share, Diluted Net loss per share - Diluted Earnings Per Share Basic and Diluted Other Disclosure [Abstract] Weighted average shares used in calculating: Earnings per share basic and diluted other disclosure. Weighted Average Number of Shares Outstanding, Basic Basic shares Weighted average shares used in calculating net loss per share - basic Weighted Average Number of Shares Outstanding, Diluted Diluted shares Weighted average shares used in calculating net loss per share - Diluted Statement of Other Comprehensive Income [Abstract] Other comprehensive loss: Other Comprehensive Income (Loss), Net of Tax [Abstract] Other comprehensive loss: Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Foreign currency translation adjustment loss Foreign currency translation adjustment Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest Comprehensive loss Statement of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Components Equity Component [Domain] Equity Component Common Stock [Member] Common Stock Preferred Stock [Member] Preferred Stock Additional Paid-in Capital [Member] Paid-in capital Retained Earnings [Member] Accumulated deflicit AOCI Including Portion Attributable to Noncontrolling Interest [Member] Accumulated other comprehensive loss Equity, Including Portion Attributable to Noncontrolling Interest Beginning balance Ending balance Stock Issued During Period Issuance of Common Stock Net of Issuance Cost, Share Issuance of common stock - private placement, net of issuance cost (in share) Stock issued during period issuance of common stock net of nssuance cost, share. Stock Issued During Period Issuance of Common Stock Net of Issuance Cost, Value Issuance of common stock - private placement, net of issuance cost Stock issued during period issuance of common stock net of issuance cost, value Stock Issued During Period, Shares, New Issues Issuance of common stock - ATM (in shares) Sale of shares Stock Issued During Period, Value, New Issues Issuance of common stock - ATM Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Vesting of restricted stock awards (in shares) APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Share-based compensation expense related to issuance of stock options and restricted stock awards Release Of Foreign Currency Translation Adjustment Release of foreign currency translation adjustment upon liquidation of a subsidiary Release of foreign currency translation adjustment.. Statement of Cash Flows [Abstract] Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Share-Based Payment Arrangement, Noncash Expense Share-based compensation expense Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Accounts Receivable Accounts receivable Increase (Decrease) in Prepaid Expense Prepaid expenses Increase (Decrease) in Other Current Assets Other current assets Increase (Decrease) in Accounts Payable, Trade Accounts payable Increase Decrease In Accrued Research And Development Accrued research and development costs The increase (decrease) during the reporting period in accrued research and development expense. Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Accrued expenses and other current liabilities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Net cash used in operating activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] CASH FLOWS FROM INVESTING ACTIVITIES: Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash used in investing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] CASH FLOWS FROM FINANCING ACTIVITIES: Proceeds from at the Offer Proceeds from ATM Proceeds from at the offer. Proceeds from Issuance of Common Stock Proceeds from private placement Proceeds from stock purchase agreement Issuance Costs Paid for Private Placement Issuance costs paid for private placement Issuance costs paid for private placement. Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by financing activities Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Effect of exchange rate changes on cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Cash and cash equivalents, beginning of period Cash and cash equivalents, end of period Organization, Consolidation and Presentation of Financial Statements [Abstract] Business Description and Basis of Presentation [Text Block] Nature of Business Accounting Policies [Abstract] Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Fair Value of Financial Instruments Investments, All Other Investments [Abstract] Investment [Text Block] Other Investment Accrued Liabilities and Other Liabilities [Abstract] Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued Expenses and Other Current Liabilities Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Text Block] Share-based Compensation Plans Earnings Per Share [Text Block] Loss per share Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Retirement Benefits [Abstract] Retirement Benefits [Text Block] Defined Contribution Plan License Agreement [Abstract] License agreement abstract. License Agreements [Text Block] License and Option Agreement The entire disclosure for license agreements. Subsequent Events [Abstract] Subsequent Events [Text Block] Subsequent Events Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Segment Reporting, Policy [Policy Text Block] Segment Information Consolidation, Variable Interest Entity, Policy [Policy Text Block] Variable Interest Entities Investment, Policy [Policy Text Block] Investment Use of Estimates, Policy [Policy Text Block] Use of Estimates Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Fair Value of Financial Instruments, Policy [Policy Text Block] Fair Value of Investment Instruments Foreign Currency Transactions and Translations Policy [Policy Text Block] Foreign Currency Translation Adjustment Related Party Accounts Receivable Policy Policy [Text Block] Accounts Receivable Disclosure of accounting policy for related party accounts receivable. Revenue from Contract with Customer [Policy Text Block] Revenue Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Selling, General and Administrative Expenses, Policy [Policy Text Block] General and Administrative Expenses Income Tax, Policy [Policy Text Block] Income taxes Patent Costs Policy [Text Block] Patent Costs Disclosure of accounting policy for patent costs. Interest And Other Income Policy Policy [Text Block] Interest and Other Income, Net Disclosure of accounting policy for interest and other income. Subsequent Events, Policy [Policy Text Block] Subsequent Events New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued/Adopted Accounting Pronouncements Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of financial assets measured at fair value on a recurring basis and indicating the level of the fair value hierarchy Other Current Liabilities [Table Text Block] Schedule of accrued expenses and other current liabilities Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Schedule of share-based compensation expense Share-Based Payment Arrangement, Option, Activity [Table Text Block] Schedule of stock option activity Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of weighted-average assumptions used in estimating the fair value of the stock options Nonvested Restricted Stock Shares Activity [Table Text Block] Summary of RSA activity Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of Basic and Diluted Net Loss Per Common Share Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Table Text Block] Schedule of earnings per share diluted by common class Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] Schedule of Components of Net Income Loss Before Income Tax Expense Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Summary of reconciliation of income taxes computed using the U.S. federal statutory rate Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Summary of deferred tax assets (liabilities) Stock, Class of Stock [Table] Schedule Of Stock By Class [Table] Investment, Name [Axis] Investment, Name [Domain] Tisento Therapeutics Holdings Inc [Member] Tisento Therapeutics Holdings Inc Tisento therapeutics holdings inc. Consolidated Entities [Axis] Consolidated Entities Consolidated Entities [Domain] Consolidated Entities Korsana Biosciences Inc [Member] Korsana Cyclerion Therapeutics Inc [Member] Cyclerion Sale of Stock [Axis] Sale of Stock Sale of Stock [Domain] Sale of Stock Two Thousand Twenty Five Equity Private Placement [Member] 2025 Equity Private Placement Two thousand twenty five equity private placement member. Series A Preferred Stock [Member] Series A Preferred Stock Series Seed Preferred Stock [Member] Series Seed Preferred Stock Statistical Measurement [Axis] Statistical Measurement Statistical Measurement [Domain] Statistical Measurement Maximum [Member] Maximum Related Party Transaction [Axis] Related Party Transaction [Domain] Sales Agreement [Member] Sales agreement. Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Cyclerion License Agreement [Member] Cyclerion Cyclerion license agreement. Akebia License Agreement [Member] Akebia Akebia license agreement. Class of Stock [Line Items] Nature of Business Payment Of Cash Milestone Additional milestone cash payment Payment of cash milestone. Up Front Payment Received Up front payment received Up Front Payment Received. Option Fee Option fee Option fee Subsequent Fees Subsequent fees subsequent fees Development Milestone Payment Development milestone payment Development milestone payment. Asset Acquisition, Consideration Transferred Cash consideration transferrred Equity Method Investment, Ownership Percentage Outstanding equity securities Equity Securities, FV-NI Equity investment in cash Shares, Issued Common stock shares issued Shares Issued, Price Per Share Common stock share purchase price Maximum Amount Of Aggregate Initial Offering Price Maximum amount of aggregate initial offering price Maximum amount of Aggregate initial offering price. Cash Commission Percentage Of Gross Proceeds Of Sales Of Common Stock Cash commission of gross proceeds of sales of common stock, percentage Cash commission percentage of gross proceeds of sales of common stock. Payments of Stock Issuance Costs Commissions paid Transaction Costs Sale of Transferred Assets Transaction costs associated with sale of transferred assets Transaction costs sale of transferred assets. Debt Instrument Convertible Threshold Percentage of Outstanding Shares Percentage of outstanding shares Debt instrument convertible threshold percentage of outstanding shares. Net Cash On Capitalization Net cash on capitalization Net cash on capitalization. Preferred Stock, Convertible, Conversion Ratio Number of common shares Stock and Warrants Issued During Period, Value, Preferred Stock and Warrants Aggregate purchase price Remaining Additional Up Front Payment Remaining additional up front payment Remaining additional up front payment. Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event [Member] Intangible Asset, Finite-Lived [Table] Schedule Of Finite Lived Intangible Assets [Table] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name Patents [Member] Patents Statement of Income Location, Balance [Axis] Income Statement Location Statement of Income Location, Balance [Domain] Income Statement Location Interest And Other Income [Member] Interest and other income, net Represents information pertaining to transactions recorded in interest and other income. Finite-Lived Intangible Assets [Line Items] Finite Lived Intangible Assets [Line Items] Professional Fees Legal and other fees Interest and Other Income Interest income generated from cash and cash equivalents balances Income Tax Examination, Penalties and Interest Accrued Income tax, penalties and interest accrued Fair Value, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents Cash and Cash Equivalents [Domain] Cash and Cash Equivalents Money Market Funds [Member] Money market funds Measurement Frequency [Axis] Measurement Frequency Measurement Frequency [Domain] Measurement Frequency Fair Value, Recurring [Member] Recurring Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV Fair Value, Inputs, Level 1 [Member] Level 1 Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Cash and Cash Equivalents, Fair Value Disclosure Total cash equivalents Equity Method Investment [Table] Minimum [Member] Minimum Minimum Valuation Approach and Technique [Axis] Valuation Approach and Technique [Domain] Weighted Average Investment [Member] Weighted average investment Weighted average investment. Terminal Decline Rate [Member] Terminal decline rate Terminal decline rate. Treasury Rate [Member] Treasury rate Treasury rate. Investment Holdings, Other than Securities [Line Items] Available-for-Sale Securities, Continuous Unrealized Loss Position, Fair Value 1 Fair value of outstanding equity securities Available-for-sale securities, continuous unrealized loss position, fair value 1. Equity Securities without Readily Determinable Fair Value, Impairment Loss, Cumulative Amount Impairment loss on other investments Investment Owned, Net Assets, Percentage Net assets percentage Accrued Professional Fees, Current Professional fees Employee-related Liabilities, Current Employee compensation Other Sundry Liabilities, Current Other Severance Costs Payment to former chief financial officer Defined Benefit Plan, Benefit Obligation Separation benefits obligation Loss Contingency Accrual Liabilities recorded for indemnification provisions Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Award Type [Axis] us-gaap_AwardTypeAxis Award Type [Domain] Restricted Stock [Member] Restricted Stock Awards Performance Shares [Member] Performance stock options Share-Based Payment Arrangement, Option [Member] Employee Stock Option Employee Stock Option Stock Options Vesting [Axis] Vesting [Domain] Title and Position [Axis] Title and Position [Domain] Director [Member] Director Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-based Compensation Plans Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares Number of shares vested Share Based Compensation Expense Share based compensation expense Share based compensation expense Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Unrecognized share-based compensation expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Expected period to recognize the expense Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant date fair value per option share Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Total intrinsic value Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Unrecognized share-based compensation expense Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Research and Development Expense [Member] Research and development General and Administrative Expense [Member] General and administrative Share-Based Payment Arrangement, Expense Share-based compensation Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Number of Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Outstanding at beginning of the year (in shares) Outstanding at end of the year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Cancelled or forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding at beginning of the year (in dollars per share) Outstanding as of December 31, 2025 Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Cancelled or forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Weighted Average Remaining Contractual Term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Aggregate Intrinsic Value, Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Aggregate Intrinsic Value, Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Weighted average risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Expected option term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected stock price volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Unvested at the beginning of the period (in shares) Unvested the end of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted-Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Unvested at the beginning of the period (in dollars per share) Unvested restricted common stock at the end of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Forfeited (in dollars per share) Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Numerator: Earnings Per Share Basic and Diluted1 [Abstract] Denominator: Earnings per share basic and diluted1. Earnings Per Share, Diluted [Abstract] Net loss per share Earnings Per Share, Diluted, by Common Class, Including Two-Class Method [Table] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Anti-dilutive securities excluded from the calculation of diluted loss per share Dilutive Securities, Effect on Basic Earnings Per Share, Options and Restrictive Stock Units Dilutive securities, effect on basic earnings per share, options and restrictive stock units Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest [Abstract] Income (Loss) from Continuing Operations before Income Taxes, Domestic Domestic Income (Loss) from Continuing Operations before Income Taxes, Foreign Foreign Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Total Pretax loss Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Income Tax Jurisdiction [Axis] Income Tax Authority Income Tax Jurisdiction [Domain] Income Tax Authority Domestic Tax Jurisdiction [Member] Federal State and Local Jurisdiction [Member] State Credit Derivatives Contract Type [Axis] Credit Derivatives Contract Type Credit Derivatives Contract Type [Domain] Credit Derivatives Contract Type Operating Loss Carryforwards [Line Items] Income Taxes Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Deferred tax assets, valuation allowance Change in valuation allowance Operating Loss Carryforwards Net operating loss carryforwards Tax Credit Carryforward, Amount Tax credit carryforwards Other Information Pertaining to Income Taxes Income tax credit expiration description Unrecognized Tax Benefits Unrecognized tax benefits Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued Accrued interest or penalties Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Effective Income Tax Rate Reconciliation [Table] Debt Instrument [Axis] Debt Instrument, Name [Domain] Effective Income Tax Rate Reconciliation [Line Items] Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount US Federal Statutory Tax Rate Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount Foreign tax effects Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount Non-deductible items Effective Income Tax Rate Reconciliation, Tax Credit, Amount Tax credits Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent US Federal Statutory Tax Rate, Percent Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent Foreign tax effects, Percent Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent Non-deductible items, Percent Effective Income Tax Rate Reconciliation, Tax Credit, Percent Tax credits, Percent Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Change in valuation allowance, Percent Effective Income Tax Rate Reconciliation, Percent Income Tax Expense (Benefit), Percent, Total Deferred Tax Assets, Net of Valuation Allowance [Abstract] Deferred tax assets: Deferred Tax Assets, Operating Loss Carryforwards Net operating loss carryforwards Deferred Tax Assets, Tax Credit Carryforwards Tax credit carryforwards Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Share-based compensation Deferred Tax Assets Capitalized Research And Development Costs Capitalized research and development Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from in-process research and development costs expensed in connection with a business combination. Deferred Tax Assets, Goodwill and Intangible Assets Intangibles Deferred Tax Assets, Gross Total deferred tax assets Deferred Tax Assets, Valuation Allowance Valuation allowance Deferred Tax Assets, Net of Valuation Allowance Net deferred tax assets Not Found During Migration Deprecated Concept Defined Contribution Pension And Other Postretirement Plans Disclosure [Abstract] Not Found During Migration Deprecated Concept Defined Contribution Pension And Other Postretirement Plans Disclosure Abstract Defined Contribution Plan [Table] Defined Contribution Plan [Table] Defined Contribution Plan Disclosure [Line Items] Defined Contribution Plan Defined Contribution Plan, Type [Extensible Enumeration] 401 (k) Savings Plan Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent Percent of compensation eligible employees may elect to contribute Defined Contribution Plan, Employer Matching Contribution, Percent of Match Matching contribution (as a percent of employee's contributions) Defined Contribution Plan Employer Matching Contribution Maximum Maximum amount of employer matching contribution The maximum amount per employee of the employer's matching contributions. Collaborative Arrangement and Arrangement Other than Collaborative [Table] Patent License Agreement [Member] Patent License Agreement [Member] Patent license agreement. Akebia Research License Agreement [Member] Akebia Research License Agreement [Member] Akebia Research License Agreement Member. Amendment Akebia Research License Agreement [Member] Amendment Akebia Research License Agreement [Member] Amendment Akebia Research License Agreement. Akebia Material Purchase Agreement [Member] Akebia Material Purchase Agreement [Member] Akebia Material Purchase Agreement. Medsteer Collaboration Agreement [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Option Additional Fee Option additional fee Option additional fee. Revenue Recognition, Milestone Method, Revenue Recognized Revenue recognized Additional Up Front Payment Additional up front payment Additional up front payment. Commercialization Milestone Payments Commercialization milestone payments Commercialization milestone payments. Payments to Acquire in Process Research and Development Payment of additional development materials Costs and Expenses Subsequent Event [Table] Scenario [Axis] Scenario [Domain] Subsequent Event [Line Items] Debt Instruments, Options, Exercise Period Exercise period Debt instruments, options, exercise period. Qualified Plan [Member]