v3.26.1
Investments - Additional Information (Details)
 12 Months Ended
Dec. 31, 2025
USD ($)
Trust
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Aug. 31, 2023
USD ($)
Dec. 31, 2021
Schedule Of Held To Maturity Securities [Line Items]          
Investment value $ 2,804,353,000        
Interest and investment income 33,281,000 $ 29,073,000 $ 87,122,000    
Amortized cost of available-for-sale investments 113,280,000 2,143,457,000      
Unrealized gain (loss) on available-for-sales investments $ 6,729,000 (10,619,000) 8,779,000    
Certain investments held in number of trusts | Trust 2        
Gross proceeds from sales of available-for-sale investments $ 2,166,763,000 0 0    
Gain on disposal of available-for-sale investments 182,714,000 0 0    
Unrealized gain (loss) on available-for-sale investments other comprehensive income (4,954,000) 0 0    
Equity investment 281,762,000 278,384,000      
Impairment charges on equity investments 0 0      
Short-term Investments          
Schedule Of Held To Maturity Securities [Line Items]          
Amortized cost of held-to-maturity debt investments 2,254,968,000 1,649,810,000      
Interest receivable 23,383,000 23,944,000      
Interest and investment income from held-to-maturity debt investments 80,855,000 66,282,000 50,425,000    
Held-to-Maturity Debt Investments, Net          
Schedule Of Held To Maturity Securities [Line Items]          
Allowance for credit lossess for interest receivable 0 0      
Short-term Equity Securities          
Schedule Of Held To Maturity Securities [Line Items]          
Interest and investment income 99,213,000 302,366,000 308,860,000    
Unrealized gain (loss) on available-for-sales investments (233,796,000) 107,795,000 282,246,000    
Long-term Investments          
Schedule Of Held To Maturity Securities [Line Items]          
Interest and investment income 7,478,000 26,418,000 9,760,000    
Amortized cost of held-to-maturity debt investments 224,421,000 206,885,000      
Interest receivable $ 2,229,000 1,385,000      
Keyvac          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage         55.00%
Evaheart          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 7.06%        
Two Trusts          
Schedule Of Held To Maturity Securities [Line Items]          
Investment value $ 460,839,000 422,733,000      
Interest and investment income $ 3,214,000 14,692,000 $ 32,334,000    
UPH          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 51.00%        
Equity investment, impairment loss   216,000      
SKY          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage       45.00%  
Equity investment       $ 103,000,000  
VIVO (Suzhou) Health Industry Investment Fund L.P.          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 12.50%        
Equity investment $ 104,411,000 96,178,000      
Total committed capital contribution 143,000,000        
Capital contributed 100,000,000        
capital contribution unpaid $ 43,000,000        
Vivo Innovation Fund II, L.P.          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 16.86%        
Equity investment $ 38,856,000 $ 34,216,000      
Total committed capital contribution 50,000,000        
Capital contributed 41,000,000        
capital contribution unpaid $ 9,000,000        
Vivo Co-Invest (S), L.P.          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 100.00% 100.00%      
Equity investment $ 8,029,000 $ 7,905,000      
BogotaBio          
Schedule Of Held To Maturity Securities [Line Items]          
Ownership Percentage 11.24%        
Unpaid cash capital contribution $ 3,120,000 $ 2,632,000