v3.26.1
Significant Accounting Policies - Additional Information (Details)
$ in Thousands, ¥ in Millions
 12 Months Ended
Dec. 31, 2025
USD ($)
Segment
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2025
CNY (¥)
Dec. 31, 2024
CNY (¥)
Dec. 31, 2022
USD ($)
Significant Accounting Policies [Line Items]            
Cash and cash equivalents and restricted cash $ 1,156,429 $ 602,217 $ 1,129,122     $ 3,886,928
Impairment charges on equity method investments 0   0      
Costs related to underutilized manufacturing capacity $ 11,575 17,198 17,300      
Value added tax rate on biological products rate 3.00%          
Sales return accrued liabilities $ 37,317 35,095        
Advertising Expense 1,168 1,020 1,883      
Employee retirement and other post-retirement benefits incurred 13,864 21,537 37,710      
Assets not under fair value hierarchy 2,804,000 5,117,000        
Foreign Currency Transaction Gain (Loss), before Tax (109,787) 61,377 75,751      
Cash and Cash Equivalents, at Carrying Value, Total $ 88,080 148,827   ¥ 616 ¥ 1,086  
Number of reporting segment | Segment 1          
Revenue Benchmark [Member] | Customer Concentration Risk [Member] | Pan American Health Organization [Member]            
Significant Accounting Policies [Line Items]            
Concentration of credit risks percentage 18.00%          
ASU 2023-09            
Significant Accounting Policies [Line Items]            
Change in Accounting Principle, Accounting Standards Update, Adopted [true false] true     true    
Change in Accounting Principle, Accounting Standards Update, Adoption Date Jan. 01, 2025     Jan. 01, 2025    
ASU 2025-10            
Significant Accounting Policies [Line Items]            
Change in Accounting Principle, Accounting Standards Update, Adopted [true false] true     true    
Change in Accounting Principle, Accounting Standards Update, Adoption Date Jan. 01, 2025     Jan. 01, 2025    
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false] true     true    
Shipping and Handling [Member]            
Significant Accounting Policies [Line Items]            
Shipping, Handling and Transportation Costs $ 11,620 $ 7,098 $ 7,631      
Minimum [Member]            
Significant Accounting Policies [Line Items]            
Value added tax rate on sale of products and provision of services 6.00%          
Maximum [Member]            
Significant Accounting Policies [Line Items]            
Value added tax rate on sale of products and provision of services 13.00%          
Use Rights [Member] | Minimum [Member]            
Significant Accounting Policies [Line Items]            
Finite-Lived Intangible Asset, Useful Life 20 years     20 years    
Use Rights [Member] | Maximum [Member]            
Significant Accounting Policies [Line Items]            
Finite-Lived Intangible Asset, Useful Life 50 years     50 years    
Computer Software | Minimum [Member]            
Significant Accounting Policies [Line Items]            
Finite-Lived Intangible Asset, Useful Life 3 years     3 years    
Computer Software | Maximum [Member]            
Significant Accounting Policies [Line Items]            
Finite-Lived Intangible Asset, Useful Life 10 years     10 years