| Summary of Short-term Investments Classifications |
Short-term investments classification as of December 31, 2025 and 2024 were shown as below:
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December 31, |
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2025 |
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2024 |
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Held-to-maturity debt investments |
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$ |
2,254,968 |
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$ |
1,649,810 |
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Available-for-sale debt investments |
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110,868 |
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2,134,316 |
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Equity securities |
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3,117,237 |
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|
5,829,202 |
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Total short-term investments |
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$ |
5,483,073 |
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$ |
9,613,328 |
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| Summary Long-term Investments Held by Company |
The following table sets forth a breakdown of the categories of long-term investments held by the Company as of the dates indicated:
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December 31, |
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2025 |
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2024 |
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Held-to-maturity debt investment |
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$ |
224,421 |
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$ |
206,885 |
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Equity method investments |
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|
281,762 |
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|
278,384 |
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Private equity investments without readily determinable fair values |
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6,141 |
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|
6,080 |
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Total long-term investments |
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$ |
512,324 |
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|
$ |
491,349 |
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| Summary of Equity Method Investments |
Equity method investments
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Equity method
investment balance |
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Share of earnings (losses) from equity method investments |
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December 31, |
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For the year ended December 31, |
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Ownership
Percentage |
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2025 |
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2024 |
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2025 |
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2024 |
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SKY Biologics Co., Ltd |
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45.00 |
% |
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$ |
76,790 |
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$ |
93,281 |
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$ |
(16,492 |
) |
|
$ |
(7,895 |
) |
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VIVO (Suzhou) Health Industry Investment Fund L.P. |
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12.50 |
% |
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104,411 |
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|
96,178 |
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|
6,538 |
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|
1,324 |
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Vivo Innovation Fund II, L.P. |
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|
16.86 |
% |
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|
38,856 |
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|
34,216 |
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|
1,785 |
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(549 |
) |
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Vivo Co-Invest (S), L.P. |
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|
100.00 |
% |
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8,029 |
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7,905 |
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(75 |
) |
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(42 |
) |
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Keyvac Biyolojik Ürünler Sanayi ve Ticaret Anonim Şirketi |
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55.00 |
% |
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34,512 |
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28,312 |
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4,809 |
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|
4,341 |
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Chongqing Evaheart MEDICAL Device Co., Ltd |
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7.06 |
% |
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11,621 |
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|
11,960 |
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(846 |
) |
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(922 |
) |
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UPH Biopharmaceutical (Private) Limited |
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|
51.00 |
% |
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— |
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— |
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— |
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(216 |
) |
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Others |
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7,543 |
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6,532 |
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|
245 |
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|
1,259 |
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Total equity method investments |
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$ |
281,762 |
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$ |
278,384 |
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|
$ |
(4,036 |
) |
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$ |
(2,700 |
) |
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