S-8 S-8 EX-FILING FEES 0001674416 CRISPR Therapeutics AG N/A Fees to be Paid 0001674416 2026-06-04 2026-06-04 0001674416 1 2026-06-04 2026-06-04 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-8

CRISPR Therapeutics AG

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee Calculation Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

1 Equity Common Shares, CHF 0.03 par value Other 17,017,693 $ 51.40 $ 874,709,420.20 0.0001381 $ 120,797.37

Total Offering Amounts:

$ 874,709,420.20

$ 120,797.37

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 120,797.37

Offering Note

1

1a. Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional common shares which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of our outstanding shares of common stock. Pursuant to Rule 416(c) under the Securities Act, this Registration Statement shall also cover an indeterminate amount of interests to be offered or sold pursuant to the employee benefit plan described herein. 1b. Amount registered represents the number of shares available for future issuance under the CRISPR Therapeutics AG 2026 Stock Option and Incentive Plan (the "2026 Plan"). 1c. Price per unit and price were estimated pursuant to Rule 457(c) and Rule 457(h) solely for the purpose of calculating the registration fee. The proposed maximum offering price per share and proposed maximum aggregate offering price are based on the average of the high and low sale prices of the Registrant's common stock as reported on The Nasdaq Global Market on June 3, 2026.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rule 457(p)
Fee Offset Claims
Fee Offset Sources