1001 - Document - Cover Page
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1002 - Statement - CONSOLIDATED BALANCE SHEETS
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1003 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)
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1004 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS
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1005 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS DEFICIT
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1006 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS DEFICIT (Parenthetical)
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1007 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS
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1008 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical)
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1009 - Disclosure - Nature of the Business
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1010 - Disclosure - Summary of Significant Accounting Policies
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1011 - Disclosure - Prepaid Expenses and Other Current Assets
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1012 - Disclosure - Property and Equipment, net
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1013 - Disclosure - Accrued Expenses
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1014 - Disclosure - Leases
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1015 - Disclosure - Debt
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1016 - Disclosure - License Agreement, Advances From Collaboration Partners, Legal, and Other Contingencies
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1017 - Disclosure - Stockholders' Deficit
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1018 - Disclosure - Stock-Based Compensation
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1019 - Disclosure - Income Taxes
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1020 - Disclosure - Net Loss Per Share
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1021 - Disclosure - Other Expense (Income), net
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1022 - Disclosure - Segment and Geographic Information
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1023 - Disclosure - Recurring Fair Value Measurements
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1024 - Disclosure - Subsequent Events
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1025 - Disclosure - Summary of Significant Accounting Policies (Policies)
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1026 - Disclosure - Summary of Significant Accounting Policies (Tables)
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1027 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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1028 - Disclosure - Property and Equipment, net (Tables)
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1029 - Disclosure - Accrued Expenses (Tables)
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1030 - Disclosure - Leases (Tables)
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1031 - Disclosure - Debt (Tables)
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1032 - Disclosure - Stockholders' Deficit (Tables)
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1033 - Disclosure - Stock-Based Compensation (Tables)
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1034 - Disclosure - Income Taxes (Tables)
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1035 - Disclosure - Net Loss Per Share (Tables)
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1036 - Disclosure - Other Expense (Income), net (Tables)
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1037 - Disclosure - Segments and Geographic Information (Tables)
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1038 - Disclosure - Recurring Fair Value Measurements (Tables)
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1039 - Disclosure - Nature of the Business - Additional Information (Detail)
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1040 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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1041 - Disclosure - Summary of Significant Accounting Policies - Summary of Useful Lives of Principal Classes of Assets (Detail)
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1042 - Disclosure - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Detail)
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1043 - Disclosure - Prepaid Expenses and Other Current Assets - Additional Information (Detail)
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1044 - Disclosure - Property and Equipment, net - Property and Equipment, Net (Detail)
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1045 - Disclosure - Property and Equipment, net - Additional Information (Detail)
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1046 - Disclosure - Accrued Expenses - Accrued Expenses (Detail)
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1047 - Disclosure - Leases - Additional Information (Detail)
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1048 - Disclosure - Leases - Summary of Remaining Operating Lease (Details)
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1049 - Disclosure - Debt - Additional Information (Detail)
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1050 - Disclosure - Debt - Schedule of Future Principal Payments for Long-Term Debt (Detail)
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1051 - Disclosure - License Agreement, Advances From Collaboration Partners, Legal, and Other Contingencies (Detail)
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1052 - Disclosure - Stockholders' Deficit - Additional Information (Detail)
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1053 - Disclosure - Stockholders' Deficit - Summary of Warrants Outstanding (Detail)
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1054 - Disclosure - Stock-Based Compensation - Additional Information (Detail)
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1055 - Disclosure - Stock-Based Compensation - Summary of Transactions Related to Grant of Stock Options to Employees and Directors (Detail)
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1056 - Disclosure - Stock-based Compensation - Summary of Assumptions Used to Estimate Fair Values of Stock Options Granted (Detail)
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1057 - Disclosure - Stock-based Compensation - Summary of Transactions Related to Grant of Restricted Stock Units to Employees (Detail)
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1058 - Disclosure - Stock-based Compensation - Summary of Allocated Stock-based Compensation Expense (Detail)
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1059 - Disclosure - Income Taxes - Components of Income (Loss) Before Taxes (Detail)
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1060 - Disclosure - Income Taxes - Additional Information (Detail)
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1061 - Disclosure - Income Taxes - Significant Components of Deferred Tax Assets (Detail)
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1062 - Disclosure - Income Taxes - Reconciliation of Expected Tax Expense with Actual Tax Expense (Detail)
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1063 - Disclosure - Net Loss Per Share - Schedule of Loss and Weighted Average Number of Shares Used in Computing Basic and Diluted Net Loss Per Share (Detail)
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1064 - Disclosure - Net Loss Per Share - Potentially Dilutive Securities Excluded from Computation of Diluted Weighted Average Shares Outstanding (Detail)
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1065 - Disclosure - Other Expense (Income), net - Schedule of Other Expense (Income) (Detail)
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1066 - Disclosure - Segments - Schedule of CODM expense categories (Detail)
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1067 - Disclosure - Recurring Fair Value Measurements (Additional Information) (Detail)
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1068 - Disclosure - Fair Value Measurements - Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis (Detail)
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1069 - Disclosure - Fair Value Measurements - Summary of The Fair Value of The Derivative Liabilities and The Warrant Liabilities, Level 3 Fair Value Estimates (Detail)
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1070 - Disclosure - Subsequent Events - Additional Information (Detail)
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Cover [Abstract]
Document Information [Table]
Entity Addresses, Address Type [Axis]
Address Type [Domain]
Business Contact [Member]
Document Information [Line Items]
Document Type
Document Type
Amendment Flag
Amendment Flag
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Entity Central Index Key
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address, Address Line One
Entity Address, City or Town
Entity Address, City or Town
Entity Address, State or Province
Entity Address, State or Province
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Entity Primary SIC Number
Contact Personnel Name
Statement of Financial Position [Abstract]
Assets [Abstract]
Assets
Assets, Current [Abstract]
Current assets:
Cash and Cash Equivalent
Cash and cash equivalents
Cash and cash equivalents
Restricted Cash, Current
Restricted cash
License Fee Receivables
License and service receivable
License Fee Receivables
Unbilled Contracts Receivable
Unbilled receivable
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Totals
Assets, Current
Total current assets
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Assets
Total assets
Liabilities and Equity [Abstract]
Liabilities and Stockholders (Deficit) Equity
Liabilities, Current [Abstract]
Current liabilities:
Accounts Payable, Current
Accounts payable
Accrued Liabilities, Current
Accrued expenses
Total
Long-Term Debt, Current Maturities
Current portion of long-term debt, net of unamortized debt discounts
Less: current portion
Deposit Liabilities, Accrued Interest
Accrued interest on debt
Advances from Collaboration Partners Current
Advances from collaboration partners
Advances from Collaboration Partners Current
Warrant liabilities Current
Warrant liabilities
Warrant liabilities Current
Operating Lease, Liability, Current
Current portion of operating lease liability
Derivative Liability, Current
Derivative liabilities
Liabilities, Current
Total current liabilities
Long-Term Debt, Excluding Current Maturities
Long-term debt, net of current portion
Operating Lease, Liability, Noncurrent
Operating lease liability
Liabilities
Total liabilities
Equity, Attributable to Parent [Abstract]
Stockholders (Deficit) equity:
Preferred Stock, Value, Issued
Preferred stock
Common Stock, Value, Issued
Common stock
Additional Paid in Capital, Common Stock
Additional paid-in capital
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Equity, Attributable to Parent
Total stockholders' deficit
Balance
Balance
Liabilities and Equity
Total liabilities and stockholders' deficit
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Preferred Stock, Shares Authorized
Preferred Stock, shares authorized
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Outstanding
Preferred Stock, shares outstanding
Common Stock, Par or Stated Value Per Share
Common stock, par value
Common Stock, Shares Authorized
Common stock, shares authorized
Common Stock, Shares, Issued
Common stock, shares issued
Common stock, shares issued
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Balance, shares
Balance, shares
Income Statement [Abstract]
Revenues
License and service revenue:
Operating Expenses [Abstract]
Operating expenses:
Research and Development Expense (Excluding Acquired in Process Cost)
Research and development
Clinical and manufacturing
General and Administrative Expense
General and administrative
Operating Expenses
Total operating expenses
Operating Income (Loss)
Loss from operations
Loss from operations
Other Nonoperating Income (Expense)
Other (income) expense, net
Total other expense (income), net
Total other expense (income), net
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Earnings Per Share, Basic
Net loss per share, basic
Earnings Per Share, Diluted
Net loss per share, diluted
Weighted Average Number of Shares Outstanding, Basic
Weighted average number of shares of common stock and pre-funded warrants used in computing net loss per share, basic
Weighted Average Number of Shares Outstanding, Diluted
Weighted average number of shares of common stock and pre-funded warrants used in computing net loss per share, diluted
Statement of Stockholders' Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components [Axis]
Equity Components
Equity Component [Domain]
Equity Component
Common Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Accumulated deficit [Member]
Sale of Stock [Axis]
Sale of Stock
Sale of Stock [Domain]
Sale of Stock
Statement [Line Items]
Statement [Line Items]
Stock Issued During Period, Value, Acquisitions
Issuance of common stock and pre-funded warrants
Stock Issued During Period, Shares, Acquisitions
Issuance of common stock and pre-funded warrants, shares
Proceeds from Issuance of Common Stock
Proceeds from the sale of common stock through ATM program, net of issuance costs
Net proceeds from common stock shares issued at public offering
Stock Issued During Period, Shares, New Issues
Sale of common stock through ATM, net of issuance costs, shares
Issuance of pre-funded warrants related to the September 2025 Domicilium debt conversion per agreement
Issuance of pre-funded warrants related to the Domicilium debt conversion
Issuance of pre-funded warrants related to the September 2025 Domicilium debt conversion per agreement
Issuance of pre-funded warrants related to Coastal Capital, LP transaction, net of issuance costs
Issuance of pre-funded warrants in connection with the 2025 PIPE transaction, net of issuance costs, Value
Issuance of pre-funded warrants related to Coastal Capital, LP transaction, net of issuance costs
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of pre-funded warrants / stock options, shares
Exercised
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Issuance restricted stock awards, share
Stock Issued During Period, Value, Restricted Stock Award, Gross
Issuance restricted stock awards, value
Restricted Stock Vested During Period Value
Vesting of restricted stock units, Value
Restricted stock vested during period value.
Restricted Stock Vested During Period Shares
Vesting of restricted stock units, shares
Restricted stock vested during period shares.
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
Issuance Of Pre Funded Warrants Under The Coastlands And Domicilium Securities Purchase Agreements Net Of Issuance Costs
Issuance of pre-funded warrants under the Coastlands and Domicilium Securities Purchase Agreements, net of issuance costs of $9k
Issuance of Pre-funded Warrants Under the Coastlands and Domicilium Securities Purchase Agreements, Net of Issuance Costs
Atthe Market Sales Agreement [Member]
At-the-market Sale Agreement [Member]
At the market sales agreement.
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Offering expenses
Issuance Of Pre-Funded Warrants
Issuance Of Pre-Funded Warrants
Statement of Cash Flows [Abstract]
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation
Depreciation
Depreciation
Depreciation expenses
Operating Lease, Right-of-Use Asset, Periodic Reduction
Amortization of operating lease right-of-use asset
Amortization of Debt Discount (Premium)
Amortization of debt discount
Change In Fair Value Of Derivative Liabilities
Increase in fair value of derivative liabilities
Change In Fair Value Of Derivative Liabilities
Imputed Interest on Bridge Loans
Imputed interest expense on 2025 bridge loans
Imputed Interest on Bridge Loans
Fair Value Adjustment of Warrants
Change in fair value of warrant liabilities
Gain on Extinguishment of Debt
Extinguishment of the 2021 Award
Gain on extinguishment of the CFF 2021 award
Gain on extinguishment of debt.
Write-off of FV of Derivative Liabilities
Write-off of fair value of derivative liabilities
Write-off of FV of Derivative Liabilities
Loss On Extinguishment Of Term Debt
Loss on extinguishment of debt
Loss on extinguishment of term debt.
Loss on Issuance of Common Stock
Loss on issuance of common stock
Loss on Issuance of Common Stock
Increase Decrease In Gain on Debt Conversion
Gain on debt conversion
Increase Decrease In Gain on Debt Conversion
Gain (Loss) on Disposition of Property Plant Equipment
Gain on sales and disposals of property and equipment
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Increase (Decrease) in License fee receivable
License and service receivable
Increase (Decrease) in License fee receivable
Increase (Decrease) in Accounts Receivable
Unbilled receivable
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other assets
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accrued Liabilities
Accrued expenses
Increase (Decrease) in Accrued Interest Payable
Accrued interest
Increase (Decrease) in Accrued Interest Payable
Increase Decrease In Operating Lease Liabilities
Operating lease liabilities
Increase (decrease) in operating lease liabilities.
Gain (Loss) on Extinguishment of Debt
Gain on extinguishment of accrued interest
Gain (loss) on extinguishment of debt
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash (used in) provided by operating activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Proceeds from Sale of Other Property, Plant, and Equipment
Proceeds from the sale of property and equipment
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by investing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Proceeds From The Issuance of Common Stock, Pre-Funded Warrants, And Common Stock Warrants
Proceeds from the issuance of common stock, pre-funded warrants, and common stock warrants, net of issuance costs
Proceeds From The Issuance of Common Stock, Pre-Funded Warrants, And Common Stock Warrants
Proceeds From Issuance of Common Stock From the Coastal Capital LP Transaction, Net Issuance Costs
Proceeds from issuance of pre-funded warrants under the Coastlands and Domicilium Securities Purchase Agreements, net of issuance costs
Proceeds From Issuance of Common Stock From the Coastal Capital LP Transaction, Net Issuance Costs
Proceeds from Issuance of Long-Term Debt
Proceeds from debt financing obligation
Repayments of Notes Payable
Repayment of term loan principal
Proceeds From Advances From Collaboration Partners
Proceeds (repayment) from advances from collaboration partners
Proceeds from advances from collaboration partners.
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by (used in) financing activities
Proceeds from Stock Options Exercised
Exercise of stock options
Proceeds From Issuance Of Pre Funded Warrants In Connection With The 2025 PIPE Transaction, Net Issuance Costs
Proceeds from issuance of pre-funded warrants in connection with the 2025 PIPE transaction, net issuance costs
Proceeds from issuance of pre-funded warrants in connection with the 2025 PIPE transaction, net issuance costs.
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase (decrease) in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, cash equivalents and restricted cash at the beginning of the year
Cash, cash equivalents and restricted cash at the end of the year
Total cash, cash equivalents and restricted cash
Reconciliation Of Cash Cash Equivalents And Restricted Cash To Condensed Consolidated Balance Sheets [Abstract]
Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheet:
Reconciliation of cash, cash equivalents and restricted cash to condensed consolidated balance sheets.
Restricted Cash and Cash Equivalent
Restricted cash
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flow activities:
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Noncash financing activities:
Fair Value of Common Stock and Pre-Funded Warrants Issued to Loan Holder
Fair value of common stock and pre-funded warrants issued to loan holder
Fair Value of Common Stock and Pre-Funded Warrants Issued to Loan Holder
Debt Conversion, Original Debt, Amount
Domicilium debt conversion
Debt Conversion, Principal Debt, Amount
Debt Conversion Principal Amount
Debt Conversion, Principal Debt, Amount
Debt Instrument, Increase, Accrued Interest
Debt Conversion Accrued Interest
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Nature of the Business
Accounting Policies [Abstract]
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Prepaid And Other Current Assets [Abstract]
Prepaid and other current assets.
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid Expenses and Other Current Assets
Prepaid expenses and other current assets.
Property, Plant and Equipment [Abstract]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, net
Payables and Accruals [Abstract]
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Leases [Abstract]
Lessee, Operating Leases [Text Block]
Leases
Debt Disclosure [Abstract]
Debt Disclosure [Text Block]
Debt
Commitments and Contingencies Disclosure [Abstract]
Legal Matters and Contingencies [Text Block]
License Agreement, Advances From Collaboration Partners, Legal, and Other Contingencies
Equity [Abstract]
Equity [Text Block]
Stockholders' Deficit
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Text Block]
Stock-Based Compensation
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Text Block]
Income Taxes
Earnings Per Share [Abstract]
Earnings Per Share [Text Block]
Net Loss Per Share
Other Income and Expenses [Abstract]
Other Income and Other Expense Disclosure [Text Block]
Other (Income) Expense, net
Segment Reporting [Abstract]
Segment Reporting Disclosure [Text Block]
Segment and Geographic Information
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Text Block]
Recurring Fair Value Measurements
Subsequent Events [Abstract]
Subsequent Events [Text Block]
Subsequent Events
Basis Of Presentation And Reclassification Policy [Text Block]
Basis of Presentation
Basis of presentation
Consolidation, Policy [Policy Text Block]
Principles of Consolidation
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Revenue [Policy Text Block]
Revenue Recognition
Receivable [Policy Text Block]
License and Service Receivable
Unbilled Receivable [Policy Text Block]
Unbilled Receivable
Unbilled Receivable [Policy Text Block]
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Foreign Currency
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Marketable Securities, Policy [Policy Text Block]
Marketable Securities
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Concentration Of Credit Risk And Off Balance Sheet Credit Exposure Policy Policy [Text Block]
Concentrations of Credit Risk and Off-Balance Sheet Risk
Concentrations of credit risk and off balance sheet risk.
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Commitments and Contingencies, Policy [Policy Text Block]
Legal and Other Contingencies
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Debt, Policy [Policy Text Block]
Debt
Income Tax, Policy [Policy Text Block]
Income Taxes
Earnings Per Share, Policy [Policy Text Block]
Net Loss per Share, Basic and Diluted
Lessee, Leases [Policy Text Block]
Leases
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Deferred Policy Acquisition Costs, Policy [Policy Text Block]
Deferred Offering Costs
Schedule Of Useful Life Of Property Plant And Equipment Table [Text Block]
Summary of Useful Lives of Principal Classes of Assets
Schedule of useful lives of property plant and equipment.
Schedule Of Prepaid Expense And Other Current Assets Table [Text Block]
Prepaid Expenses and Other Current Assets
Schedule of prepaid expense and other current assets.
Property, Plant and Equipment [Table Text Block]
Property and equipment, net
Schedule of Accrued Liabilities [Table Text Block]
Accrued expenses
Lease, Cost [Table Text Block]
Summary of operating lease cost
Schedule of Maturities of Long-Term Debt [Table Text Block]
Schedule of Future Principal Payments for Long-Term Debt
Schedule Of Warrant Activity Table [Text Block]
Summary of Warrants Outstanding
Schedule of warrant activity.
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
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Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Member]
Restricted stock units, unvested portion
Restricted Stock Awards [Member]
Restricted Stock Awards [Member]
Restricted Stock Awards [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Transactions Related to Grant of Stock Options to Employees and Directors
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Assumptions Used to Estimate Fair Values of Stock Options Granted
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of Transactions Related to Grant of Restricted Stock Units to Employees
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Allocated Stock-based Compensation Expense
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Components of Income (Loss) Before Taxes
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Significant Components of Deferred Tax Assets
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Reconciliation of Expected Tax Expense with Actual Tax Expense
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Loss and Weighted Average Number of Shares Used in Computing Basic and Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Potentially Dilutive Securities Excluded from Computation of Diluted Weighted Average Shares Outstanding
Schedule of Other Nonoperating Income (Expense) [Table Text Block]
Schedule of Other Expense (Income)
Significant Expense Categories [Table Text Block]
Significant CODM expense categories
Significant Expense Categories [Table Text Block]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Summary of The Fair Value of The Derivative Liabilities and The Warrant Liabilities, Level 3 Fair Value Estimates
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Statistical Measurement [Axis]
Statistical Measurement
Statistical Measurement [Domain]
Statistical Measurement
Minimum [Member]
Minimum [Member]
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Scenario [Axis]
Scenario [Domain]
Vesting [Axis]
Vesting [Domain]
Share-Based Payment Arrangement, Tranche One [Member]
First Tranche [Member]
Share-Based Payment Arrangement, Tranche Two [Member]
Second Tranche [Member]
Share-Based Payment Arrangement, Tranche Three [Member]
Third Tranche [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Coastlands Securities Agreement [Member]
Coastlands Securities Agreement [Member]
Coastlands Securities Agreement Member
Domicilium Securities Purchase Agreement [Member]
Domicilium Securities Purchase Agreement [Member]
Domicilium Securities Purchase Agreement [Member]
Debt Instrument [Axis]
Debt Instrument
Debt Instrument, Name [Domain]
Debt Instrument, Name
Hercules Loan Agreement [Member]
Hercules Term Loan Agreement [Member]
Hercules loan agreement.
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event Type
Subsequent Event [Member]
Subsequent Event [Member]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Aggregate Amount Of Milestone Payment
Sales milestones
Aggregate milestone payment
Aggregate amount of milestone payment.
Sale Of Stock Authorized Amount Of Common Stock
Sale of stock, authorized amount of common stock
Sale of stock, authorized amount of common stock.
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrant exercise price per share
Exercise Price
Cash And Cash Equivalent And Available For Sale Debt Securities
Cash, cash equivalents and marketable securities
Cash and cash equivalent and available for sale debt securities.
Debt Securities
Securities
Debt Securities, Held-to-Maturity, Purchase
New Money Investment
Proceeds from Other Debt
Proceeds received
Sale of Stock, Consideration Received Per Transaction
Sale of Stock, Consideration Received Per Transaction
Stock Issued During Period, Shares, Other
Issuance of warrant
Sale of Stock, Consideration Received on Transaction
Sale of Stock, Consideration Received on Transaction
Additional Cash And Cash Equivalent And Available For Sale Debt Securities
Additional cash and cash equivalent and available for sale debt securities
Additional cash and cash equivalent and available for sale debt securities.
Accounting Policies [Table]
Accounting Policies [Table]
Accounting Policies [Table]
Revision of Prior Period [Axis]
Revision of Prior Period
Revision of Prior Period [Domain]
Revision of Prior Period
Related Party Transaction [Axis]
Related Party Transaction [Domain]
Product and Service [Axis]
Product and Service
Product and Service [Domain]
Product and Service
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Impairment of Long-Lived Assets to be Disposed of
Impairment of long-lived assets
Asset Impairment Charges
Asset Impairment
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Assets, transfer from level 2 to level 3
Unrecognized Tax Benefits
Liability for unrecognized tax benefits
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Interest or penalties related to uncertain tax positions
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Computer Equipment [Member]
Computers and software [Member]
Furniture and Fixtures [Member]
Office furniture and equipment [Member]
Equipment [Member]
Laboratory Equipment [Member]
Leasehold Improvements [Member]
Leasehold improvement [Member]
Maximum [Member]
Maximum [Member]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment, Useful Life
Estimated useful life of asset
Property Plant And Equipment Useful Life Description
Estimated useful life of asset, description
Property plant and equipment useful life, description.
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Prepaid Research And Development Current
Research and development
Prepaid research and development current.
Prepaid Insurance
Insurance
Other Prepaid Expense, Current
Other
Prepaid Deferred Offering Costs
Deferred offering costs
Prepaid deferred offering costs.
Deferred Offering Costs
Deferred Offering Costs
Laboratory Equipment [Member]
Laboratory equipment [Member]
Laboratory equipment.
Property, Plant and Equipment, Gross
Total property and equipment, at cost
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: Accumulated depreciation and amortization
Sale Of Property Plant And Equipment
Sale of property and equipment
Sale of property plant and equipment.
Accrued Research And Development Expense Current
Research and development
Accrued research and development expense current.
Employee-related Liabilities, Current
Payroll, bonus and other employee-related expenses
Accrued Professional Fees, Current
Professional services
Other Accrued Liabilities, Current
Other
Leases [Table]
Leases [Table]
Leases.
Real Estate, Type of Property [Axis]
Real Estate [Domain]
Office Space Lease [Member]
Office Space Lease [Member]
Geographical [Axis]
Geographical
Geographical [Domain]
Geographical
Leases [Line Items]
Leases [Line Items]
Leases.
Area of Land
Land for office space lease
Lease, Cost [Abstract]
Lease cost
Operating Lease, Cost
Operating lease cost
Operating Lease, Weighted Average Remaining Lease Term
Weighted average remaining lease term
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate
Cash Paid for Amounts Included in the Measurement of Lease Liabilities Operating Cash Flows
Cash paid for amounts included in the measurement of lease liabilities, included in operating cash flows
Cash Paid for Amounts Included in the Measurement of Lease Liabilities Operating Cash Flows
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Hercules Term Loan Agreement [Member]
Hercules Term Loan Agreement [Member]
Hercules term loan agreement.
Hercules Term Loan Agreement
Domicilium Term Loan [Member]
Domicilium Term Loan [Member]
Debt Investment and Equity Issuance [Member]
Debt Investment and Equity Issuance [Member]
Debt Investment and Equity Issuance [Member]
Royalty Agreement [Member]
Royalty Agreement [Member]
Royalty Agreement [Member]
Long-Term Debt, Type [Axis]
Long-term Debt, Type
Long-Term Debt, Type [Domain]
Long-term Debt, Type
Tranche One Advance [Member]
Tranche 1 Advance [Member]
Tranche one advance.
Tranche One A Advance [Member]
Tranche 1A Advance [Member]
Tranche One A Advance [Member]
Tranche One B Advance [Member]
Tranche 1B Advance [Member]
Tranche One B Advance [Member]
Tranche Two Advance [Member]
Tranche 2 Advance [Member]
Tranche two advance.
Tranche Three Advance [Member]
Tranche 3 Advance [Member]
Tranche three advance.
Term Loan Advances [Member]
Term Loan Advances [Member]
Term Loan Advances [Member]
Bridge Loans [Member]
Bridge Loans [Member]
Two Thousand Twenty Four Bridge Loans [Member]
2024 Bridge Loans [Member]
Two Thousand Twenty Four Bridge Loans [Member]
Two Thousand Twenty Five Bridge Loans [Member]
2025 Bridge Loans [Member]
Two Thousand Twenty Five Bridge Loans [Member]
Variable Interest Rate [Axis]
Variable Rate
Variable Interest Rate [Domain]
Variable Rate
Prime Rate [Member]
Prime Rate [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Long-Term Debt
Aggregate principal amount of initial loan advance
Carrying value of debt
Long term debt
Debt Instrument, Interest Rate Terms
Debt instrument, interest rate terms
Debt Instrument, Basis Spread on Variable Rate
Loan, floating interest rate
Long-Term Debt, Percentage Bearing Variable Interest, Percentage Rate
Loan, interest rate
Debt Instrument, Maturity Date
Loan, maturity date
Debt Instrument Principal Amount Percentage
Loan, principal amount percentage
Debt instrument principal amount percentage.
Long-Term Debt, Gross
Loan, principal outstanding
Total future principal payments
Debt Instrument, Unamortized Discount
Loan, unamortized debt discount
Less: unamortized discount
Interest Expense, Debt
Loan, interest expense
Imputed Interest
Imputed interest
Imputed Interest
Plus Prime Rate
Plus Prime Rate
Plus Prime Rate
Debt Instrument, Interest Rate, Stated Percentage
Debt interest rate
Short-Term Debt, Average Outstanding Amount
Outstanding principal value
Short Term Debt, Outstanding Amount
Amortization of Debt Issuance Costs
Debt amortization charge
Qualified cash balance
Qualified cash balance
Qualified cash balance
Qualified Cash Balance Reverted
Qualified cash reverted
Qualified Cash Balance Reverted
Amortization of Debt Issuance Costs and Discounts
Equity issuance of debt discount
Debt Conversion, Converted Instrument, Amount
Debt conversion amount
Revenue-Based Payment Percentage
Revenue-based payment percentage
Revenue-Based Payment Percentage
Interest Expense, Debt, Excluding Amortization
Interest Expense, Debt, Amortization
Bridge Loan
Milestone Payments
Milestone Payments
Company Received Cash
Company Received Cash
Company Received Cash
Conversion of Stock, Amount Issued
Debt coverted into equity
Loan conversion
Class of Warrant or Right, Outstanding
Pre-Funded Warrants
Warrants Outstanding
Warrants and Rights Outstanding
Outstanding debt
Return for a pre-funded warrant
Line of Credit Facility, Increase, Accrued Interest
Accrued interest
Waive Additional Accrued and Unpaid Interest Related
Unpaid interest
Waive additional accrued and unpaid interest
Waive Additional Accrued and Unpaid Interest Related
Debt Instrument, Convertible, Conversion Price
Conversion Price
Repayment of Long-Term Debt, Long-Term Lease Obligation, and Capital Security
Repayment of Principal
Long-Term Debt, Maturity, Year One
2026
Legal And Other Contingencies [Table]
Legal And Other Contingencies [Table]
Legal and other contingencies.
Research and Development Arrangement [Member]
Research and Development Agreements [Member]
Technion Research And Development Foundation Ltd [Member]
Technion Research and Development Foundation Ltd [Member]
Technion Research and Development Foundation Ltd.
Elox - Cystic Fibrosis Foundation [Member]
Elox - CFF [Member]
Elox - Cystic Fibrosis Foundation [Member]
Almirall License Agreement [Member]
Almirall License Agreement
Almirall License Agreement Member
Israel Innovation Authority [Member]
Israel Innovation Authority [Member]
Israel Innovation Authority [Member]
Cystic Fibrosis Foundation [Member]
Cystic fibrosis foundation.
Elox - Phase Two Clinical Development [Member]
Elox - Phase Two Clinical Development [Member]
Elox - Phase Two Clinical Development [Member]
License and Service [Member]
License and Service [Member]
Two Thousand Nineteen Cystic Fibrosis Foundation Award [Member]
2019 CFF Award [Member]
Two Thousand Nineteen Cystic Fibrosis Foundation Award [Member]
Two Thousand Twenty Two Cystic Fibrosis Foundation Agreement [Member]
2022 CFF Award [Member]
Two Thousand Twenty Two Cystic Fibrosis Foundation Agreement [Member]
Two Thousand Twenty One Cystic Fibrosis Foundation Award [Member]
2021 CFF Award [Member]
Two Thousand Twenty One Cystic Fibrosis Foundation Award
Two Thousand Twenty Five Cystic Fibrosis Foundation Agreement [Member]
2025 CFF Award [Member]
Two Thousand Twenty Five Cystic Fibrosis Foundation Agreement [Member]
Statement of Financial Position Location, Balance [Axis]
Balance Sheet Location
Statement of Financial Position Location, Balance [Domain]
Balance Sheet Location
Legal And Other Contingencies [Line Items]
Legal And Other Contingencies [Line Items]
Legal and other contingencies.
Funding Award Amount Received
Funding award amount received
Funding award amount received.
Upfront Payment Received
Upfront payment received
Upfront payment received.
Transaction Price
Total transaction price
Transaction Price
Gain (Loss) on Fair Value Hedges Recognized in Earnings
Gain (loss) on fair value recognized
Regulatory Milestone
Regulatory Milestone
Regulatory Milestone
Remaining Amount Of Award Payable Upon Achievement Certain Clinical Development Milestones
Remaining amount of award payable upon achievement certain clinical development milestones
Remaining amount of award payable upon achievement certain clinical development milestones.
Other Liabilities, Current
Other liabilities current
Derivative Liability
Derivative liabilities
Percentage Of Consideration Received For Disposition Event
Percentage Of Consideration Received For Disposition Event
Percentage Of Consideration Received For Disposition Event
Award To Fund Development Milestones Amount
Award to fund development milestones
Award to fund development milestones amount.
Other Income
Other income
Cost of Revenue
Revenue
Proceeds From Research And Development Grants
Research and development grants received
Proceeds from research and development grants.
Royalty Payment Percentage On Net Sales
Royalty payment as percentage of net sales
Royalty payment percentage on net sales.
Embedded Derivative, Gain (Loss) on Embedded Derivative, Net
Value of the embedded derivative
Maximum Repayment Percentage Of Grants Received From Office Of Chief Scientist
Repayment percentage of grants received
Maximum repayment percentage of grants received from office of chief scientist.
Research and Development Expense
Research and development expense
Total research and development
Contingent Liability Related To Grants Received Royalties Payable Including Accrued L I B O R Interest
Royalty received including accrued LIBOR interest
Contingent liability related to grants received royalties payable including accrued LIBOR interest.
Clinical And Regulatory Milestone Payments Received
Clinical and regulatory milestone payments received
Clinical and regulatory milestone payments received.
Payments for Royalties
Royalties
Patent Expenses Due To Harvard
Patent Expenses Due To Harvard
Patent Expenses Due To Harvard
Related Party Transaction Percentage Of Expenses
Related party transaction percentage of expenses
Related party transaction percentage of expenses.
Stock, Class of Stock [Table]
Investment, Name [Axis]
Investment, Name [Domain]
Domicilium [Member]
Domicilium Member
September Two Thousand Twenty Three Purchase Agreement [Member]
September 2023 Purchase Agreement [Member]
September Two Thousand Twenty Three Purchase Agreement [Member]
Sales Agreement [Member]
Sales Agreement [Member]
Sales agreement.
Coastlands Securities Purchase Agreement [Member]
Coastlands Securities Purchase Agreement
Coastlands Member
Coastlands Securities Purchase Agreement [Member]
September 2023 Warrants [Member]
September 2023 Warrants [Member]
September 2023 Warrants
September 2023 Warrants [Member]
September Two Thousand Twenty Three Placement Agent Warrants [Member]
September 2023 Placement Agent Warrants [Member]
September Two Thousand Twenty Three Placement Agent Warrants [Member]
ATM Program [Member]
ATM Program [Member]
ATM Program
Initial Coastlands Closing [Member]
Initial Coastlands Closing
Initial Coastlands Closing [Member]
Coastlands First Tranche Closing [Member]
Coastlands First Tranche Closing
Coastlands First Tranche Closing [Member]
Coastlands Second Tranche Closing [Member]
Coastlands Second Tranche Closing
Coastlands Second Tranche Closing [Member]
Valuation Approach and Technique [Axis]
Valuation Approach and Technique [Domain]
Black-Scholes model [Member]
Black-Scholes model [Member]
Black-Scholes model [Member]
January 2024 Pre-Funded Warrant [Member]
January 2024 Pre-Funded Warrant
January 2024 Pre-Funded Warrant [Member]
Counterparty Name [Axis]
Counterparty Name
Counterparty Name [Domain]
Counterparty Name
Class of Stock [Line Items]
Amount Allocated
Amount allocated to Coastlands
Amount Allocated
Marketable Securities
Purchased securities
Cash Collateral for Borrowed Securities
Securities for cash consideration
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Number of common stock in warrant
Equity Method Investment, Ownership Percentage
Percentage ownership
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-Free Rate
Proceeds from Issuance of Warrants
Issuance of 2023 Common Warrants and Placement Agent Warrants
Long-Duration Contracts, Assumptions by Product and Guarantee, Volatility Rate
Volatility
total gross proceeds
Total Gross Proceeds
total gross proceeds
Class Of Warrant Or Right Expiration Period
Term (years)
Class of warrant or right expiration period.
Fair Value Inputs Probability Of Outcome
Fair value inputs probability of outcome
Fair Value Inputs Probability Of Outcome
Net cash proceeds
Net cash proceeds
Net cash proceeds
Sale of Stock, Price Per Share
Common stock public offering price
Proceeds From Issuance Of Common Stock Warrants
Purchase of pre-funded warrants
Proceeds From Issuance Of Common Stock Warrants
Aggregate Offering Price
Aggregate offering price
Aggregate offering price.
Percentage Of Sales Agents Commission On Gross Proceeds Of Sales Of Common Stock
Percentage of sales agents commission
Percentage of sales agents commission on gross proceeds of sales of common stock.
Share Price
Share Price
Common Stock Exercise Price
Common stock exercise price
Common Stock Exercise Price
Purchase Price Per Share
Purchase price per share
Purchase Price Per Share
Trading Activity [Axis]
Trading Activity, by Type [Domain]
Disposal Group Classification [Axis]
Disposal Group Classification [Domain]
SVB Warrants [Member]
SVB Warrants
SVB Warrants [Member]
September 2023 Placement Agent Warrants [Member]
September 2023 Placement Agent Warrants
September 2023 Placement Agent Warrants [Member]
January 2024 Common Stock Warrant [Member]
January 2024 Common Stock Warrant
January 2024 Common Stock Warrant [Member]
August Two Thousand Twenty Five Pre Funded Warrant [Member]
August 2025 Pre-Funded Warrant
August Two Thousand Twenty Five Pre Funded Warrant [Member]
September Two Thousand Twenty Five Pre Funded Warrant [Member]
September 2025 Pre-Funded Warrant
September Two Thousand Twenty Five Pre Funded Warrant [Member]
December Two Thousand Twenty Five Pre Funded Warrant [Member]
December 2025 Pre-Funded Warrant
December Two Thousand Twenty Five Pre Funded Warrant [Member]
February 2026 PreFunded Warrants [Member]
March 2026 PreFunded Warrants [Member]
Debt Instrument, Issuance Date
Issuance Date
Class Of Warrant Or Right Exercisable Expiration Period
Contractual life remaining (years)
Class Of warrant or right exercisable expiration period.
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Plan Name
Two Thousand And Eighteen Plan [Member]
2018 Plan [Member]
Two thousand and eighteen plan.
Title and Position [Axis]
Title of Individual
Title and Position [Domain]
Title of Individual
Board of Directors Chairman [Member]
Board Of Directors [Member]
Common Stock, Capital Shares Reserved for Future Issuance
Number of shares of common stock reserved
Share Repurchase Program, Remaining Authorized, Number of Shares
Shares remaining and available for issuance
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Contractual Life
Contractual life of stock options granted
Share-based compensation arrangements by share based payment award options grants in period contractual life.
Share Based Compensation Arrangement By Share Based Payment Award Exercisable Period Of Vested Options
Exercisable period of vested options
Share-based compensation arrangement by share-based payment award exercisable period of vested options.
Stock Option, Exercise Price, Decrease
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
Incremental stock compensation charge
Share Based Compensation Arrangement By Share Based Payment Vested During Period Fair Value
Fair value of shares vested
Share Based Compensation Arrangement By Share Based Payment Vested During Period Fair Value
Share Based Compensation Arrangement By Share Based Payment Exercises During Period Fair Value
Fair value of shares exercised
Share Based Compensation Arrangement By Share Based Payment Exercises During Period Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Options to purchase common stock granted
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value of options granted
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to outstanding other than options
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized compensation cost expected to be recognized over a weighted-average period
Share-Based Compensation Arrangement By Share Based Payment Award Options Grants Percent in Period
Grants Percent
Share-Based Compensation Arrangement By Share Based Payment Award Options Grants Percent in Period
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Fair value of restricted stock units vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted grant-date fair value
Granted
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized compensation expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Options outstanding, Beginng Balance
Options outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted average exercise price per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Options outstanding, Beginning Balance
Options outstanding, Ending Balance
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Weighted average remaining contractual life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Options exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value [Abstract]
Aggregate intrinsic value
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Options outstanding, Beginning Balance
Options outstanding, Ending Balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Granted Intrinsic Value
Granted
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Granted Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Volatility, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Volatility, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk free interest rate, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk free interest rate, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price
Exercise Price
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Unvested, Beginning Balance
Unvested, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Cancelled in Period
Cancelled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Cancelled in Period
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Repurchase in Period
Repurchased
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Repurchase in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted average grant date fair value price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Unvested, Beginning Balance
Unvested, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Cancelled Fair Value
Cancelled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Cancelled Fair Value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Repurchase Fair Value
Repurchased
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Repurchase Fair Value
Statement of Income Location, Balance [Axis]
Income Statement Location
Statement of Income Location, Balance [Domain]
Income Statement Location
Research and Development Expense [Member]
Research and Development Expense [Member]
General and Administrative Expense [Member]
General and Administrative Expense [Member]
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Income tax disclosure.
ISRAEL
Israel [Member]
AUSTRALIA
Australia
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Income tax disclosure.
Income (Loss) from Continuing Operations before Income Taxes, Domestic
U.S.
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Israel
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before taxes on income
Income Tax Jurisdiction [Axis]
Income Tax Authority
Income Tax Jurisdiction [Domain]
Income Tax Authority
State and Local Jurisdiction [Member]
State [Member]
Israel Tax Authority [Member]
Israel Tax Authority [Member]
Domestic Tax Jurisdiction [Member]
Tax Period [Axis]
Tax Period
Tax Period [Domain]
Tax Period
Earliest Tax Year [Member]
Earliest Tax Year [Member]
Latest Tax Year [Member]
Latest Tax Year [Member]
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Valuation allowance
Deferred Tax Assets, Net of Valuation Allowance
Net deferred tax asset
Net deferred tax assets
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Change in valuation allowance
Operating Loss Carryforwards
Net operating loss carryforwards
Net Operating Loss Carryforward Expiration Year
U.S. net operating loss expiry, beginning period
Net Operating Loss Carryforward Expiration Year
Operating Loss Carryforwards Not Subject To Expiration
U.S. federal NOL carryforwards, not subject to expiration
Operating loss carryforwards not subject to expiration.
Net Operating Loss Carryforwards Eligible To Offset Taxable Income Maximum
Net operating loss carryforwards eligible to offset taxable income, maximum
Net operating loss carryforwards eligible to offset taxable income, maximum.
Deferred Tax Assets, Tax Credit Carryforwards, Research
Federal research tax credit carryforwards
Federal Research Credits Carryforwards Expiration Year
Federal research tax credit expiry, beginning period
Federal Research Credits Carryforwards Expiration Year
Income Tax Examination, Description
Income tax examination, description
Deferred Tax Assets, Gross [Abstract]
Deferred tax assets:
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock-based compensation
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals
Reserves and allowances
Deferred Tax Assets, Tax Credit Carryforwards
U.S. tax credits and other credits
Deferred Tax Asset, In-Process Research and Development
Capitalized research and development expenditures
Deferred Tax Assets Operating Lease Right Of Use Assets
Operating lease right-of-use assets
Deferred tax assets operating lease right-of-use assets.
Deferred Tax Assets Operating Lease Liabilities
Operating lease liabilities
Deferred tax assets operating lease liabilities.
Deferred Tax Assets, Other
Other
Deferred Tax Assets, Gross
Total deferred tax assets
Effective Income Tax Rate Reconciliation [Table]
Foreign Tax Jurisdiction [Member]
UNITED STATES
Effective Income Tax Rate Reconciliation [Line Items]
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
U.S. federal statutory rate , Amount
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
U.S. federal statutory rate
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State tax rate, net of federal effect, Amount
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State tax rate, net of federal benefit
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount
Statutory tax rate difference between Israel and United States, Amount
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Statutory tax rate difference between Israel and United States
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
U.S. Changes in valuation allowances, Amount
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
U.S. Changes in valuation allowances
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Amount
Other items, Amount
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Percent
Other items
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Amount
Research and development credit, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Percent
Research and development credit
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Amount
Stock compensation, Amount
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Stock compensation
Effective Income Tax Rat eReconciliation Warrant valuation Amount
Warrant valuation, Amount
Effective Income Tax Rat eReconciliation Warrant valuation Amount
Effective Income Tax RatE Reconciliation Warrant Valuation Percentage
Warrant valuation
Effective Income Tax RatE Reconciliation Warrant Valuation Percentage
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount
Other nontaxable or nondeductible items, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Other nontaxable or nondeductible items
Effective Income Tax Rate Reconciliation, Percent
Income tax provision
Net Income Loss Available To Common Stockholders Basic And Diluted [Abstract]
Numerator:
Net income loss available to common stockholders basic and diluted.
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Denominator:
Antidilutive Security, Excluded EPS Calculation [Table]
Antidilutive Securities [Axis]
Antidilutive Securities, Name [Domain]
Options To Purchase Common Stock [Member]
Options to Purchase Common Stock [Member]
Options to purchase common stock.
Restricted Stock [Member]
Restricted stock awards, unvested portion
Warrant [Member]
Common Warrant [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Total potential common stock equivalents
Interest Expense, Other
Interest expense
Interest and Other Income
Interest income
Increase (Decrease) in Derivative Liabilities
Change in fair value of derivative liabilities
Gain (Loss) on Disposition of Assets for Financial Service Operations
Gain on sale of fixed assets
(Gain) Loss on Debt Extinguishment
Loss on debt extinguishment
(Gain) loss on debt extinguishment
Nonoperating Income (Expense)
Other expense
Schedule of Segment Reporting Information, by Segment [Table]
Consolidation Items [Axis]
Consolidation Items [Domain]
Operating Segments [Member]
Segments Member
Segment Reporting Information [Line Items]
Research and Development Expense, Software (Excluding Acquired in Process Cost)
Other research and development
Fair Value, Investments, Entities that Calculate Net Asset Value Per Share [Table]
Monte Carlo Simulation [Member]
Monte Carlo Simulation [Member]
Monte Carlo Simulation [Member]
Placement Agent Warrants [Member]
Placement Agent Warrants [Member]
Fair Value, Investments, Entities that Calculate Net Asset Value Per Share [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value, Inputs, Level 3 [Member]
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents [Domain]
Money Market Funds [Member]
Measurement Frequency [Axis]
Measurement Frequency [Domain]
Fair Value, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure
Money market funds included in cash and cash equivalents
Warrant liabilities
Warrant liabilities
Warrant liabilities
Embedded Derivative, Fair Value of Embedded Derivative Liability
Derivative liabilities
Fair value of derivative liabilities, beginning of year
Fair value of derivative liabilities, end of year
Platform Operator, Crypto Asset [Table]
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair Value Of Warrant Liabilities
Fair value of warrant liabilities, beginning of year
Fair value of warrant liabilities, end of year
Fair value of warrant liabilities.
Issuance Of Common Warrants And Placement Agent Warrants
Issuance of September 2023 Warrants and September 2023 Placement Agent Warrants
Issuance of Common Warrants and Placement Agent Warrants.
Change in fair value of Common Warrants and Placement Agent Warrants
Change in fair value of September 2023 Warrants and September 2023 Placement Agent Warrants
Change in fair value of Common Warrants and Placement Agent Warrants
Subsequent Event [Table]
Subsequent Event [Table]
Related and Nonrelated Parties [Axis]
Related Party
Related and Nonrelated Parties [Domain]
Related Party
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Common Stock Upon Conversion Of Warrant Exercise Shares
Common stock upon conversion of warrant exercise shares
Common Stock Upon Conversion Of Warrant Exercise Shares
Proceeds from Warrant Exercises
Proceeds from Warrant Exercises
Rescission Of Warrant Exercises Shares
Rescission of warrant exercises shares
Rescission of warrant exercises shares.
Stockholders' Equity, Reverse Stock Split