0001645460 2026-06-03 2026-06-03 0001645460 1 2026-06-03 2026-06-03 iso4217:USD pure shares S-8 S-8 EX-FILING FEES 0001645460 Cue Biopharma, Inc. N/A false S-8 Cue Biopharma, Inc. Equity Common Stock, $0.001 par value per share true 2327826 20.49 47697154.74 0.0001381 6586.98 47697154.74 6586.98 0.00 6586.98 (1) In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions. (2) Consists of 2,327,826 shares of common stock issuable under the Cue Biopharma, Inc. 2026 Stock Incentive Plan. (3) Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Registrant's Common Stock as reported on the Nasdaq Capital Market on May 27, 2026.