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  <xs:element id="ste_FairValueOfPlanAssetsDomain" abstract="true" name="FairValueOfPlanAssetsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_OtherPostRetirementBenefitPlansNetMember" abstract="true" name="OtherPostRetirementBenefitPlansNetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_NetAmortizationAndDeferral" abstract="false" name="NetAmortizationAndDeferral" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_SynergyHealthPLCPlanMember" abstract="true" name="SynergyHealthPLCPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_IsotronMember" abstract="true" name="IsotronMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_DanikenMember" abstract="true" name="DanikenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_RadebergMember" abstract="true" name="RadebergMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_AllershausenMember" abstract="true" name="AllershausenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_HarwellDosimetersMember" abstract="true" name="HarwellDosimetersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_HealthcarePrescriptionDrug" abstract="false" name="HealthcarePrescriptionDrug" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ste_AssumptionsUsedInCalculatingBenefitObligationsAndNetPeriodicBenefitCostAxis" abstract="true" name="AssumptionsUsedInCalculatingBenefitObligationsAndNetPeriodicBenefitCostAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ste_SignificantAssumptionsUsedToDetermineNetPeriodicBenefitCostsDomain" abstract="true" name="SignificantAssumptionsUsedToDetermineNetPeriodicBenefitCostsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_SignificantAssumptionsUsedToDeterminNetPeriodicBenefitCostsAxis" abstract="true" name="SignificantAssumptionsUsedToDeterminNetPeriodicBenefitCostsAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="ste_InsuranceContract" abstract="false" name="InsuranceContract" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_EquitySecurityTrusts" abstract="false" name="EquitySecurityTrusts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_DefinedContributionPlanFairValueOfPlanAssets" abstract="false" name="DefinedContributionPlanFairValueOfPlanAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_SterisCorporationSharesHeldInDefinedContributionPlan" abstract="false" name="SterisCorporationSharesHeldInDefinedContributionPlan" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ste_FairValueOfSterisCorporatioStockHeldInDefinedContributionPlan" abstract="false" name="FairValueOfSterisCorporatioStockHeldInDefinedContributionPlan" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_DefinedContributionPlanDividendsPaid" abstract="false" name="DefinedContributionPlanDividendsPaid" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_CommercialCommitmentsMember" abstract="true" name="CommercialCommitmentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_LongtermConstructionContractsMemberMember" abstract="true" name="LongtermConstructionContractsMemberMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_IllinoisEOLitigationMember" abstract="true" name="IllinoisEOLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_FixedOperatingLeaseExpense" abstract="false" name="FixedOperatingLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_Lettersofcreditassecurityforselfinsuranceriskandretentionpolicies" abstract="false" name="Lettersofcreditassecurityforselfinsuranceriskandretentionpolicies" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_VariableOperatingLeaseExpense" abstract="false" name="VariableOperatingLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_Operatingleaselongandshorttermliabilitycombined" abstract="false" name="Operatingleaselongandshorttermliabilitycombined" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_UnusualOrInfrequentItemOrBothTariffsEstimatedRefundAmount" abstract="false" name="UnusualOrInfrequentItemOrBothTariffsEstimatedRefundAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_HealthcareSegmentMember" abstract="true" name="HealthcareSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_OperatingIncomeLossBeforeAdjustments" abstract="false" name="OperatingIncomeLossBeforeAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_Amortizationandimpairmentofacquiredintangibleassets" abstract="false" name="Amortizationandimpairmentofacquiredintangibleassets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_Redomiciliationcosts" abstract="false" name="Redomiciliationcosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_Amortizationofinventoryandpropertystepuptofairvalue" abstract="false" name="Amortizationofinventoryandpropertystepuptofairvalue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_HealthcareProductsandLifeSciencesMember" abstract="true" name="HealthcareProductsandLifeSciencesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_OtherForeignEntitiesMemberMember" abstract="true" name="OtherForeignEntitiesMemberMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_CapitalequipmentrevenuesMember" abstract="true" name="CapitalequipmentrevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_ConsumablerevenuesMember" abstract="true" name="ConsumablerevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_ServicerevenuesMember" abstract="true" name="ServicerevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_OtherforeignlocationsMember" abstract="true" name="OtherforeignlocationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_DeferredOrdinaryShares" abstract="false" name="DeferredOrdinaryShares" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ste_ParValueEurosofDeferredOrdinaryShares" abstract="false" name="ParValueEurosofDeferredOrdinaryShares" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_OutgoingRepurchaseProgramMember" abstract="true" name="OutgoingRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_NewRepurchaseProgramMember" abstract="true" name="NewRepurchaseProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_OrdinaryStockRepurchasesNotIncludingSharesWithheldforTaxes" abstract="false" name="OrdinaryStockRepurchasesNotIncludingSharesWithheldforTaxes" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ste_LongTermIncentivePlanMember" abstract="true" name="LongTermIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ste_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRightsAnnualVestingPercentage" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRightsAnnualVestingPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ste_ShareBasedPaymentArrangementByShareBasedPaymentAwardVestingRequirementYearsOfServiceForEmployeesOfASpecifiedAge" abstract="false" name="ShareBasedPaymentArrangementByShareBasedPaymentAwardVestingRequirementYearsOfServiceForEmployeesOfASpecifiedAge" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ste_ShareBasedPaymentArrangementByShareBasedPaymentAwardVestingRequirementYearsOfService" abstract="false" name="ShareBasedPaymentArrangementByShareBasedPaymentAwardVestingRequirementYearsOfService" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ste_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ste_CommonStockFairMarketValuePerShare" abstract="false" name="CommonStockFairMarketValuePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="ste_SECSchedule1209ReserveCasualtyLossMember" abstract="true" name="SECSchedule1209ReserveCasualtyLossMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
