<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019e1d10-c32b-789f-8ec5-07e4e9fadde8,g:07eb80ca-aafd-4014-b4ad-ae70449cd29e-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.corcept.com/role/CoverPage" xlink:type="simple" xlink:href="cort-20260521.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.corcept.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_019e1d10-c32b-78ad-9a5f-3e6e33994dcf" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_DocumentType_019e1d10-c32b-78ad-9a5f-3e6e33994dcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_019e1d10-c32b-7fda-91eb-5fec0f189300" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_DocumentPeriodEndDate_019e1d10-c32b-7fda-91eb-5fec0f189300" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_019e1d10-c32b-75de-999b-30ee33842d36" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityRegistrantName_019e1d10-c32b-75de-999b-30ee33842d36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_019e1d10-c32b-7bc6-a837-9a2519f7129b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityIncorporationStateCountryCode_019e1d10-c32b-7bc6-a837-9a2519f7129b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_019e1d10-c32b-7b19-b687-0c1bf3a56c2b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityFileNumber_019e1d10-c32b-7b19-b687-0c1bf3a56c2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_019e1d10-c32b-7b27-8e1c-640bbfb748c9" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityTaxIdentificationNumber_019e1d10-c32b-7b27-8e1c-640bbfb748c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_019e1d10-c32b-7d43-bbe9-efc88a16342d" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityAddressAddressLine1_019e1d10-c32b-7d43-bbe9-efc88a16342d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_019e1d10-c32b-720b-99d2-842a5ae0d587" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityAddressCityOrTown_019e1d10-c32b-720b-99d2-842a5ae0d587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_019e1d10-c32b-70d7-a831-e782371f7eef" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityAddressStateOrProvince_019e1d10-c32b-70d7-a831-e782371f7eef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_019e1d10-c32b-7850-8fb5-8ac471247d87" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityAddressPostalZipCode_019e1d10-c32b-7850-8fb5-8ac471247d87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_019e1d10-c32b-7016-9b03-e2257c635057" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_CityAreaCode_019e1d10-c32b-7016-9b03-e2257c635057" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_019e1d10-c32b-7fc2-b87c-2eb2c379db66" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_LocalPhoneNumber_019e1d10-c32b-7fc2-b87c-2eb2c379db66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInformationFormerLegalOrRegisteredName_019e1d10-c32b-70f4-ac29-04084d2d2c54" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityInformationFormerLegalOrRegisteredName"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityInformationFormerLegalOrRegisteredName_019e1d10-c32b-70f4-ac29-04084d2d2c54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_019e1d10-c32b-7255-877f-4872dc98dfef" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_WrittenCommunications_019e1d10-c32b-7255-877f-4872dc98dfef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_019e1d10-c32b-72de-86b5-c8facbbef851" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_SolicitingMaterial_019e1d10-c32b-72de-86b5-c8facbbef851" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_019e1d10-c32b-72d1-86a9-4677e065a131" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_PreCommencementTenderOffer_019e1d10-c32b-72d1-86a9-4677e065a131" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_019e1d10-c32b-7b91-bfd8-fc6aa0aa7186" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_019e1d10-c32b-7b91-bfd8-fc6aa0aa7186" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_019e1d10-c32b-7953-b739-a98e82bedd8b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_Security12bTitle_019e1d10-c32b-7953-b739-a98e82bedd8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_019e1d10-c32b-74a4-9f8d-b21079d4322d" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_TradingSymbol_019e1d10-c32b-74a4-9f8d-b21079d4322d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_019e1d10-c32b-7f3e-b072-88e1b034767b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_SecurityExchangeName_019e1d10-c32b-7f3e-b072-88e1b034767b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_019e1d10-c32b-7025-abb0-52a251782a59" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityEmergingGrowthCompany_019e1d10-c32b-7025-abb0-52a251782a59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_019e1d10-c32b-77f8-8fac-2c280d321e61" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_EntityCentralIndexKey_019e1d10-c32b-77f8-8fac-2c280d321e61" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_019e1d10-c32b-7eb2-be82-d1f2b5ebe997" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e1d10-c32b-7bc3-96c0-0156c6801a19" xlink:to="loc_dei_AmendmentFlag_019e1d10-c32b-7eb2-be82-d1f2b5ebe997" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
