<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019e6599-2e71-7354-bba3-a7414918a9cd,g:0a555079-a8bb-428f-8390-2dced29dd61a-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.five9.com/role/CoverPage" xlink:type="simple" xlink:href="fivn-20260526.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.five9.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_019e6599-2e71-78e0-8cca-ec729c1ecb55" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_DocumentType_019e6599-2e71-78e0-8cca-ec729c1ecb55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_019e6599-2e71-7fbe-bf15-169ddd4f7190" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_DocumentPeriodEndDate_019e6599-2e71-7fbe-bf15-169ddd4f7190" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_019e6599-2e71-7fd7-8f07-9319d0093623" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityRegistrantName_019e6599-2e71-7fd7-8f07-9319d0093623" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_019e6599-2e71-7b5a-af1c-479bac7d2e6f" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityIncorporationStateCountryCode_019e6599-2e71-7b5a-af1c-479bac7d2e6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_019e6599-2e71-7975-862f-5fc99f8f46b6" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityFileNumber_019e6599-2e71-7975-862f-5fc99f8f46b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_019e6599-2e71-7181-bac7-11d659ba3586" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityTaxIdentificationNumber_019e6599-2e71-7181-bac7-11d659ba3586" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_019e6599-2e71-793f-9033-bcf8e680669c" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityAddressAddressLine1_019e6599-2e71-793f-9033-bcf8e680669c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_019e6599-2e71-7382-b999-7fda23747fb2" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityAddressAddressLine2_019e6599-2e71-7382-b999-7fda23747fb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_019e6599-2e71-77bb-b37d-26dc0f65d332" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityAddressCityOrTown_019e6599-2e71-77bb-b37d-26dc0f65d332" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_019e6599-2e71-721c-b69a-d76f1a027de1" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityAddressStateOrProvince_019e6599-2e71-721c-b69a-d76f1a027de1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_019e6599-2e71-75d5-9979-2939a35be873" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityAddressPostalZipCode_019e6599-2e71-75d5-9979-2939a35be873" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_019e6599-2e71-7f40-84d3-e4d3904e4409" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_CityAreaCode_019e6599-2e71-7f40-84d3-e4d3904e4409" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_019e6599-2e71-7f5f-a737-3ff47586a2d8" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_LocalPhoneNumber_019e6599-2e71-7f5f-a737-3ff47586a2d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_019e6599-2e71-76d6-86fa-c8d6fa79f902" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_WrittenCommunications_019e6599-2e71-76d6-86fa-c8d6fa79f902" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_019e6599-2e71-782a-9819-d46a25786901" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_SolicitingMaterial_019e6599-2e71-782a-9819-d46a25786901" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_019e6599-2e71-71c2-a1f9-2d4c96f4d644" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_PreCommencementTenderOffer_019e6599-2e71-71c2-a1f9-2d4c96f4d644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_019e6599-2e71-7e0e-91a5-7505419239a2" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_019e6599-2e71-7e0e-91a5-7505419239a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_019e6599-2e71-719f-9ce5-00b79445dfd2" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_Security12bTitle_019e6599-2e71-719f-9ce5-00b79445dfd2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_019e6599-2e71-705f-a445-f65c6f2856f4" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_TradingSymbol_019e6599-2e71-705f-a445-f65c6f2856f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_019e6599-2e71-76b0-a7f8-330864c12638" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_SecurityExchangeName_019e6599-2e71-76b0-a7f8-330864c12638" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_019e6599-2e71-76ef-894d-b8d938ea7cae" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityEmergingGrowthCompany_019e6599-2e71-76ef-894d-b8d938ea7cae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_019e6599-2e71-7b7e-a335-404d49759b66" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_EntityCentralIndexKey_019e6599-2e71-7b7e-a335-404d49759b66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_019e6599-2e71-750e-851b-f06958ce6a66" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_AmendmentFlag_019e6599-2e71-750e-851b-f06958ce6a66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_019e6599-2e71-7c3f-8392-200a01cc460d" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_019e65f6-ec1d-7ed3-a914-a9f570177612" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019e6599-2e71-76a7-aff3-e5a95f32d1aa" xlink:to="loc_dei_CurrentFiscalYearEndDate_019e65f6-ec1d-7ed3-a914-a9f570177612" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
