<?xml version="1.0" encoding="UTF-8"?>
<edgarSubmission xmlns:com="http://www.sec.gov/edgar/common" xmlns="http://www.sec.gov/edgar/npx">
  <headerData>
    <submissionType>N-PX</submissionType>
    <filerInfo>
      <registrantType>IM</registrantType>
      <liveTestFlag>LIVE</liveTestFlag>
      <filer>
        <issuerCredentials>
          <cik>0000090498</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>
      <periodOfReport>06/30/2024</periodOfReport>
    </filerInfo>
  </headerData>
  <formData>
    <coverPage>
      <yearOrQuarter>YEAR</yearOrQuarter>
      <reportCalendarYear>2024</reportCalendarYear>
      <reportingPerson>
        <name>SIMMONS FIRST NATIONAL CORP</name>
        <phoneNumber>8705411000</phoneNumber>
        <address>
          <com:street1>501 MAIN STREET</com:street1>
          <com:city>PINE BLUFF</com:city>
          <com:stateOrCountry>AR</com:stateOrCountry>
          <com:zipCode>71601</com:zipCode>
        </address>
      </reportingPerson>
      <reportInfo>
        <reportType>INSTITUTIONAL MANAGER NOTICE REPORT</reportType>
        <noticeExplanation>REPORTING PERSON DID NOT EXERCISE VOTING</noticeExplanation>
        <confidentialTreatment>N</confidentialTreatment>
      </reportInfo>
      <fileNumber>028-04801</fileNumber>
      <leiNumber>549300IVR5AJKUVOGN05</leiNumber>
      <explanatoryInformation>
        <explanatoryChoice>N</explanatoryChoice>
      </explanatoryInformation>
    </coverPage>
    <signaturePage>
      <reportingPerson>SIMMONS FIRST NATIONAL CORP</reportingPerson>
      <txSignature>Daniel Hobbs</txSignature>
      <txPrintedSignature>Daniel Hobbs</txPrintedSignature>
      <txTitle>EVP Chief Financial Officer</txTitle>
      <txAsOfDate>05/27/2026</txAsOfDate>
    </signaturePage>
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