0001683553 2026-05-21 2026-05-21 false 0001683553 8-K 2026-05-21 Spruce Biosciences, Inc. DE 001-39594 81-2154263 611 Gateway Boulevard Suite 740 South San Francisco CA 94080 415 343-5986 false false false false Common Stock, par value $0.0001 per share SPRB NASDAQ false