75000 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 75010 - Statement - Condensed consolidated balance sheets (unaudited) link:presentationLink link:calculationLink link:definitionLink 75020 - Statement - Condensed consolidated balance sheets (unaudited) (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 75030 - Statement - Condensed consolidated statements of operations and comprehensive loss link:presentationLink link:calculationLink link:definitionLink 75040 - Statement - Condensed consolidated statements of convertible preferred stock and stockholders' deficit (unaudited) link:presentationLink link:calculationLink link:definitionLink 75050 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited) link:presentationLink link:calculationLink link:definitionLink 995455 - Disclosure - Nature of the Business link:presentationLink link:calculationLink link:definitionLink 995465 - Disclosure - Summary of significant accounting policies link:presentationLink link:calculationLink link:definitionLink 995475 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 995485 - Disclosure - Fair Value of Financial Assets and Liabilities link:presentationLink link:calculationLink link:definitionLink 995495 - Disclosure - Prepaid Expenses and Other Current Assets link:presentationLink link:calculationLink link:definitionLink 995505 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 995515 - Disclosure - Accrued Expenses and Other Current Liabilities link:presentationLink link:calculationLink link:definitionLink 995525 - Disclosure - Convertible Preferred Stock link:presentationLink link:calculationLink link:definitionLink 995535 - Disclosure - Common Stock link:presentationLink link:calculationLink link:definitionLink 995545 - Disclosure - Stock-based Compensation link:presentationLink link:calculationLink link:definitionLink 995555 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 995565 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 995575 - Disclosure - Commitments and contingencies link:presentationLink link:calculationLink link:definitionLink 995585 - Disclosure - Related Party Transactions link:presentationLink link:calculationLink link:definitionLink 995595 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 995605 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 995615 - Disclosure - Summary of significant accounting policies (Policies) link:presentationLink link:calculationLink link:definitionLink 995625 - Disclosure - Marketable securities (Tables) link:presentationLink link:calculationLink link:definitionLink 995635 - Disclosure - Prepaid Expenses and Other Current Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 995645 - Disclosure - Fair Value of Financial Assets and Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 995655 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 995665 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 995675 - Disclosure - Convertible Preferred Stock (Tables) link:presentationLink link:calculationLink link:definitionLink 995685 - Disclosure - Common Stock (Tables) link:presentationLink link:calculationLink link:definitionLink 995695 - Disclosure - Stock-based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 995705 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 995715 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 995725 - Disclosure - Nature of the Business - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995735 - Disclosure - Marketable Securities - Schedule of Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 995745 - Disclosure - Marketable Securities - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995755 - Disclosure - Fair Value of Financial Assets and Liabilities - Summary Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 995765 - Disclosure - Fair Value of Financial Assets and Liabilities - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995775 - Disclosure - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 995785 - Disclosure - Leases - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995795 - Disclosure - Leases - Schedule of Lease Costs (Details) link:presentationLink link:calculationLink link:definitionLink 995805 - Disclosure - Leases - Summary of Future Minimum Lease Payments under Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 995815 - Disclosure - Leases - Summary of Future Minimum Lease Payments under Operating Leases (Details) 2 link:presentationLink link:calculationLink link:definitionLink 995825 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 995835 - Disclosure - Convertible Preferred Stock - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995845 - Disclosure - Convertible Preferred Stock - Schedule of Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 995855 - Disclosure - Common Stock - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995865 - Disclosure - Common Stock - Schedule of Common Stock Shares Reserved for Future Issuance (Details) link:presentationLink link:calculationLink link:definitionLink 995875 - Disclosure - Stock-based Compensation - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995885 - Disclosure - Stock-based Compensation - Schedule of Stock Option Valuation Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 995895 - Disclosure - Stock-based Compensation - Schedule of Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 995905 - Disclosure - Stock-based Compensation - Schedule of Stock-based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 995915 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995925 - Disclosure - Net Loss Per Share - Summary of Potentially Dilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders (Details) link:presentationLink link:calculationLink link:definitionLink 995935 - Disclosure - Commitments and contingencies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995945 - Disclosure - Related Party Transactions - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995955 - Disclosure - Segment Reporting - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 995965 - Disclosure - Segment Reporting - Summary of Expense Categories Reviewed (Details) link:presentationLink link:calculationLink link:definitionLink 995975 - Disclosure - Subsequent Events - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink Unallocated research and development and other Other Research and Development Expense Unallocated research and development and other Entity Incorporation, State or Country Code Ribupatide injection Ribupatide Injection [Member] Ribupatide Injection Member Increase (Decrease) in Accounts Payable Increase (Decrease) in Accounts Payable, Total Accounts payable Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash investing and financing activities: Plan Name [Axis] Equity [Abstract] Entity Current Reporting Status US Government Agencies Debt Securities [Member] U.S. Government Agency Debt Securities Operating expenses Operating Expenses [Abstract] Fair Value, Inputs, Level 2 [Member] Fair Value, Inputs, Level 2 Commitments and Contingencies Disclosure [Text Block] Commitments and contingencies Common stock, shares authorized Common Stock, Shares Authorized MASSACHUSETTS Waltham, Massachusetts Preferred stock, par value Temporary Equity, Par or Stated Value Per Share Accrued Expenses and Other Liabilities, Current The amount of current portion of accrued expenses and other liabilities as at the end of the reporting period. Total accrued expenses and other current liabilities Preferred Stock, Voting Rights Voting right shares Document Fiscal Period Focus Entity Shell Company Preferred stock, shares outstanding Temporary Equity, Shares Outstanding Balance at end of period, convertible preferred stock, shares Balance at beginning of period, convertible preferred stock, shares Expected contractual obligation Contractual Obligation Contractual Obligation, Total Other Accrued Liabilities, Current Other Cash and cash equivalents Cash and Cash Equivalent Cash and Cash Equivalent, Total Noncash Lease Income (Expense) Noncash lease income (expense). Non-cash lease expense Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Common Stock, Shares, Issued Common stock, shares issued Statement [Table] Restricted cash Restricted Cash, Noncurrent 2024 Equity Incentive Plan Two Thousand Twenty Four Equity Incentive Plan [Member] Two Thousand Twenty Four Equity Incentive Plan. Statement [Line Items] Entity Filer Category Total liabilities, convertible preferred stock and stockholders' deficit Liabilities and Equity Payables and Accruals [Abstract] Payments to Acquire Marketable Securities Purchases of marketable securities Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted-average exercise price, Exercisable Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents License and Collaboration Agreement [Member] License and collaboration agreement. License and collaboration agreement Subsequent Event [Line Items] Other Noncash Income (Expense) Other Noncash Income (Expense), Total Other Series A Two Preferred Stock [Member] Series A-2 preferred stock. Series A-2 preferred stock Options to Purchase Common Stock Geographical [Domain] Oral Ribupatide Oral Ribupatide [Member] Oral Ribupatide. Incentive stock option percentage Share Based Compensation Arrangement by Share Based Payment Award, Incentive Stock Option, Percentage Share based compensation arrangement by share based payment award, incentive stock option, percentage. Additional paid-in capital Additional Paid in Capital, Common Stock Summary of significant accounting policies Significant Accounting Policies [Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Number of options, Granted Number of common shares issued Equity compensation plans Share-Based Payment Arrangement [Member] Net loss per share attributable to common stockholders - basic Earnings Per Share, Basic Earnings Per Share, Basic, Total Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Number of options outstanding, Beginning balance Number of options outstanding, Ending balance Interest income Interest Income (Expense), Nonoperating Interest Income (Expense), Nonoperating, Total Liabilities, Current Total current liabilities Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Consolidation Items [Domain] Changes in instrument-specific credit risk Fair Value, Option, Credit Risk, Gains (Losses) on Assets Equity, Attributable to Parent [Abstract] Stockholders' deficit: Entity Small Business Series B Convertible Preferred Stock [Member] Series B convertible preferred stock. Series B Convertible Preferred Stock [Member] Series B Convertible Preferred Stock Retained Earnings (Accumulated Deficit) Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Additional share purchase obligation, shares Additional Share Purchase Obligation Number of Shares The obligation for the holders of the share to purchase additional shares. Nature of Operations [Text Block] Nature of the Business Number of options, Cancelled or forfeited Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Proceeds from Issuance Initial Public Offering Gross proceeds from initial public offering Price per share Sale of Stock, Price Per Share Share-Based Payment Arrangement [Text Block] Stock-based Compensation Organization, Consolidation and Presentation of Financial Statements [Abstract] Leases [Abstract] Accrued Research And Development Expenses, Current Carrying amount as of the balance sheet date of current portion of accrued research and development expenses. Accrued other research and development Lessee, Lease, Description [Line Items] Amendment Flag Loss Contingencies [Line Items] Liabilities and Equity [Abstract] Liabilities, convertible preferred stock and stockholders' deficit Entity Address, Postal Zip Code Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Increase (Decrease) in Operating Lease Liability Operating lease liabilities CODM Description Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description Common Stock [Member] Common Stock Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted-average exercise price, Granted Weighted-average grant-date fair value of stock options granted Interest Receivable, Current Interest receivable Lessee, Operating Lease, Liability, to be Paid, Year Three 2029 Other Operating Income (Expense), Net Other income (expense), net Debt Securities, Available-for-Sale [Line Items] Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Entity Address, Address Line One Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Stock Option Valuation Assumptions Fair Value Hierarchy and NAV [Axis] Earnings Per Share [Abstract] Temporary Equity, Carrying Amount, Attributable to Parent Convertible preferred stock Carrying value Balance at beginning of period, convertible preferred stock Balance at end of period, convertible preferred stock Weighted average incremental borrowing rate Operating Lease Weighted Average Incremental Borrowing Rate Operating lease weighted average incremental borrowing rate. Operating Lease, Right-of-Use Asset Operating lease right-of-use assets Debt Securities, Available-for-Sale, Unrealized Loss Position Debt Securities, Available-for-Sale, Unrealized Loss Position, Total Total fair market value in an unrealized loss position Document Type Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Entity Central Index Key Debt Securities, Available-for-Sale [Table Text Block] Schedule of Marketable Securities Investments, Debt and Equity Securities [Abstract] Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation Net decrease in cash, cash equivalents and restricted cash Subsequent Event Type [Domain] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities excluded from computation of diluted net loss per share attributable to common stockholders Common Stock, Par or Stated Value Per Share Common stock, par value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted-average remaining contractual term (years), Outstanding Debt Securities, Available-for-Sale, Amortized Cost Amortized Cost Amortized cost Debt Securities, Available-for-Sale Debt Securities, Available-for-Sale, Total Fair Value Technology transfer fee Technology Transfer Fee Technology transfer fee. Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Number of options, Exercised Exercise of stock options (in shares) Prepaid Bonuses Prepaid bonuses. Prepaid bonuses Accrued Liabilities, Current Accrued Liabilities, Current, Total Accrued expenses and other current liabilities Accrued expenses Current Fiscal Year End Date Percentage of preferred stock holding total capital Debt Instrument, Convertible, Threshold Percentage of Preferred Stock Holding Total Capital Debt instrument, convertible, threshold percentage of preferred stock holding total capital. KAI-4729 [Member] KAI-4729. KAI-4729 Document Quarterly Report Fair Value, by Balance Sheet Grouping [Table] Entity Address, State or Province Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Gross Unrealized Gains Common Stock, Capital Shares Reserved for Future Issuance Total shares of authorized common stock reserved for future issuance Geographical [Axis] Conversion of Stock, Shares Converted Conversion of preferred stock Marketable Securities, Current Marketable securities Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Accrued Expenses and Other Current Liabilities Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Equity Option [Member] Stock Option Other Comprehensive Income (Loss), Net of Tax [Abstract] Other comprehensive loss Maturities of marketable securities Proceeds from Sale and Maturity of Marketable Securities Subsequent Event [Member] Subsequent Events Area of Office Space Area of office space. Area of office space Other non-current assets Other Assets, Noncurrent Antidilutive Securities [Axis] Schedule of Stock-based Compensation Expense Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Related Party Transaction [Axis] AOCI Attributable to Parent [Member] Accumulated other comprehensive (loss) income Cash and Cash Equivalents [Domain] Maturity date Debt Instrument, Maturity Date Marketable Securities Noncurrent [Member] Marketable securities, noncurrent. Long-term Marketable Securities Minimum [Member] Minimum Financial Instrument [Axis] Assets, Current [Abstract] Current assets: Fair Value, Inputs, Level 3 [Member] Fair Value, Inputs, Level 3 Segment Reporting [Abstract] Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Summary Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis Current liabilities: Liabilities, Current [Abstract] Related Party Transactions [Abstract] Shares, Outstanding Balance at beginning of period, shares Balance at end of period, shares Clinical and Regulatory Milestone Payments Clinical and regulatory milestone payments. Clinical and regulatory milestone payments Series A-2 Nonvoting Convertible Preferred Stock Series A-2 Nonvoting Convertible Preferred Stock [Member] Series A-2 nonvoting convertible preferred stock. Restricted Cash and Cash Equivalent Restricted Cash and Cash Equivalent, Total Restricted cash Commitments and Contingencies Commitments and contingencies (Note 12) General and Administrative Expense [Member] General and Administrative Share Based Compensation Arrangement by Share Based Payment Award, Common Stock Fair Market Value, Percentage Share based compensation arrangement by share based payment award, common stock fair market value, percentage. Fair market value percentage of common stock Operating Lease, Liability Total lease liabilities Total lease liabilities Issuance of equity awards Stock Issued During Period, Shares, Incentive Stock Purchase Plans Number of shares issued during the period as a result of an incentive award purchase plan. Marketable Securities, Noncurrent Long-term marketable securities Commercial Milestone Payments Commercial milestone payments. Commercial milestone payments Lessee, Lease, Description [Table] Interest Income (Expense), Operating Interest Income (Expense), Operating, Total Interest income Loss Contingencies [Table] Weighted Average Number of Shares Outstanding, Basic Weighted Average Number of Shares Outstanding, Basic, Total Weighted-average common stock outstanding - basic Temporary Equity [Abstract] Convertible preferred stock: Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Aggregate intrinsic value, Exercisable Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Subsequent Events [Text Block] Subsequent events Related Party Transactions Disclosure [Text Block] Related Party Transactions APIC, Share-Based Payment Arrangement, Increase for Cost Recognition APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation expense Emerging Growth Company Status and Smaller Reporting Company Status [Policy Text Block] Emerging growth company status and smaller reporting company status. Emerging growth company status and smaller reporting company status Equity, Attributable to Parent Total stockholders' deficit Balance at end of period Balance at beginning of period Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Lessee, Operating Lease, Existence of Option to Extend [true false] Option to extend the lease Statement of Stockholders' Equity [Abstract] Prepaid Other Research and Development Expenses Prepaid other research and development expenses. Prepaid other research and development Temporary Equity, Par Value Cash consideration Combined voting power Share Based Compensation Arrangement by Share Based Payment Award, Combined Voting Power, Percentage Share based compensation arrangement by share based payment award, combined voting power, percentage. Over-Allotment Option [Member] Underwriters Overallotment Entity Address, Address Line Two Fair Value Disclosures [Text Block] Fair Value of Financial Assets and Liabilities Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Schedule of Accrued Expenses and Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] Debt Instrument, Name [Domain] Other Assets, Current Other Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Plan Name [Domain] Preferred Stock, Convertible, Conversion Ratio Conversion ratio Entity Address, City or Town Number of Reportable Segments Number of reporting segment Security Exchange Name Schedule of Preferred Stock Temporary Equity [Table Text Block] Prepaid clinical Prepaid Clinical Expenses Current Prepaid clinical expenses current. Series A Convertible Preferred Stock [Member] Series A Convertible Preferred Stock. Series A Convertible Preferred Stock [Member] Antidilutive Securities, Name [Domain] Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation, Ending Balance Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation, Beginning Balance Total cash, cash equivalents and restricted cash Statistical Measurement [Domain] Total current assets Assets, Current Share-Based Payment Arrangement, Expense Stock-based compensation expense Document Period End Date Fair Value Hierarchy and NAV [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Number of options, Exercisable Statement of Financial Position [Abstract] Increase In Base Rent Percentage Increase in base rent percentage. Percentage of annual increase in rent Antidilutive Security, Excluded EPS Calculation [Table] Reconciliation of cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract] Class of Stock [Axis] Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Number of securities in unrealized loss position Liabilities Total liabilities Financial Instruments [Domain] Lessee, Operating Lease, Liability, to be Paid, Year Two 2028 Prepaid Expense and Other Assets, Current [Abstract] Series A-2 Convertible Preferred Stock [Member] Series A-2 convertible preferred stock. Series A-2 Convertible Preferred Stock Weighted-average common stock outstanding - diluted Weighted Average Number of Shares Outstanding, Diluted Weighted Average Number of Shares Outstanding, Diluted, Total Entity File Number Unrealized loss on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized loss Cover [Abstract] Payments for Repurchase of Initial Public Offering Payments of deferred offering costs related to initial public offering Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Total Number of operating segment Number of Operating Segments Sale of Stock [Domain] Segment Reporting Disclosure [Text Block] Segment Reporting General and Administrative Expense General and Administrative Expense, Total General and administrative General and administrative Series B Preferred Stock [Member] Series B preferred stock Total Series A-2 Convertible Preferred Stock [Member] Total Series A-2 Convertible Preferred Stock. Total Series A-2 Convertible Preferred Stock Conversion price Preferred Stock, Convertible, Conversion Price Temporary Equity, Liquidation Preference Liquidation preference Subsequent Event [Table] Operating Lease, Expense Operating lease base rent Lessee Operating Lease Liability Payments Due After Year Four and Thereafter Lessee operating lease liability payments due after year four and thereafter. 2031 and thereafter Share Based Compensation Arrangement by Share Based Payment Award, Term of Stock Options Share based compensation arrangement by share based payment award, term of stock options. Term of stock options New Accounting Pronouncements, Policy [Policy Text Block] Recently issued and adopted accounting pronouncements Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Summary of Future Minimum Lease Payments under Operating Leases Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Stock options vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Lessee, Operating Lease, Term of Contract Term of agreement Common Stock, Shares, Outstanding Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common stock, shares outstanding Operating Lease, Liability, Current Operating lease liabilities, current Depreciation, Depletion and Amortization Depreciation, Depletion and Amortization, Total Depreciation and amortization expense Document Transition Report Series A-2 (NV) convertible preferred stock [Member] Series A-2 (NV) convertible preferred stock. Series A-2 (NV) Convertible Preferred Stock Operating Expenses Total operating expenses Research and development Research and Development Expense Research and Development Expense, Total Research and development expense Research and development Lessee, Operating Leases [Text Block] Leases Convertible Preferred Stock [Member] Convertible Preferred Stock Statement of Cash Flows [Abstract] Share-Based Payment Arrangement, Option, Activity [Table Text Block] Schedule of Stock Option Activity Ribupatide oral Ribupatide Oral [Member] Ribupatide Oral [Member] Preferred stock, liquidation value Preferred Stock, Liquidation Preference, Value Equity [Text Block] Common Stock Earnings Per Share [Text Block] Net Loss Per Share Net loss Net loss Net loss Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Aggregate intrinsic value, Outstanding Change in fair value of preferred stock tranche right liability Change in Fair Value of Preferred Stock Tranche Right Liability Change in fair value of preferred stock tranche right liability. Other Nonoperating Income Other income, net Operating Lease, Cost Operating lease costs Unaudited Interim Financial Information Policy [Policy Text Block] Unaudited interim financial information policy policy text block Unaudited interim financial information Preferred Stock, Convertible, Shares Issuable Common stock issuable upon conversion Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Operating Lease, Payments Cash payments for operating leases Assets Assets [Abstract] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Document Fiscal Year Focus Debt Conversion, Converted Instrument, Shares Issued Shares issued to convert notes Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Cash flows from investing activities: Accounts payable Accounts Payable, Current Accounts Payable, Current, Total Research and Development Expense [Member] Research and Development Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Increase (Decrease) in Other Noncurrent Assets Other non-current assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Prepaid Expenses and Other Current Assets Debt Conversion, Converted Instrument, Amount Aggregate purchase price Non Refundable Upfront Payment in Cash Non refundable upfront payment in cash. Non-refundable upfront payment Series A-1 Convertible Preferred Stock Series A-1 Convertible Preferred Stock [Member] Series A-1 convertible preferred stock. Proceeds from Stock Options Exercised Proceeds from the exercise of stock options Fair Value Disclosures [Abstract] Commitments and Contingencies Disclosure [Abstract] Schedule of Prepaid Expenses And Other Current Assets [Table Text Block] Tabular disclosure of prepaid expenses and other current assets. Schedule of Prepaid Expenses and Other Current Assets Lessee, Operating Lease, Liability, to be Paid, Year One 2027 Operating Leases, Rent Expense Base rent Debt Instrument [Axis] Derivative Instrument [Axis] Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total Unrecognized compensation cost Accrued Interest Accrued interest. Accrued interest Assets, Fair Value Disclosure Total assets Sale of Stock [Axis] Series A One Preferred Stock [Member] Series A - 1 preferred stock. Series A-1 preferred stock Marketable Securities Current [Member] Marketable securities, current. Marketable Securities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by (used in) investing activities Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Debt Conversion, Converted Instrument, Rate Interest rate Accrued Clinical, Current Carrying amount as of the balance sheet date of current portion of accrued clinical expenses. Accrued clinical Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted-average exercise price, Cancelled or forfeited Money Market Funds [Member] Money Market Funds Income Tax Disclosure [Text Block] Income taxes Allowances for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss Debt Securities, Available-for-Sale, Allowance for Credit Loss, Ending Balance Debt Securities, Available-for-Sale, Allowance for Credit Loss, Beginning Balance Debt Securities, Available-for-Sale, Allowance for Credit Loss, Total Preferred stock, shares issued Temporary Equity, Shares Issued Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year 2026 Other non-current liabilities Other Liabilities, Noncurrent Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Letters of Credit Outstanding, Amount Letter of credit outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding, Weighted-average exercise price, Beginning Balance Outstanding, Weighted-average exercise price, Ending Balance Preferred Stock [Text Block] Convertible preferred stock Income Tax Disclosure [Abstract] Additional Paid-in Capital [Member] Additional paid-in capital Measurement Frequency [Domain] Statement of Income Location, Balance [Axis] Trading Symbol Related Party Transaction [Table] Subsequent Event Type [Axis] Accrued employee compensation and benefits Employee-related Liabilities, Current Employee-related Liabilities, Current, Total Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Cash flows from financing activities: Expected option life (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Fair Value, Recurring [Member] Fair Value, Recurring Entity Ex Transition Period Percentage Of Capital Stock Issued Percentage of capital stock issued. Shares issued as a percentage of outstanding capital stock Lessee, Operating Lease, Liability, to be Paid Total lease payments Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: interest Equity Components [Axis] Equity Component [Domain] Percentage of Lease Incremental Borrowing Rate Percentage of lease incremental borrowing rate. Incremental borrowing rate IPO [Member] Initial Public Offering Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock Stock options expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Common Stock, Voting Rights Voting right Maximum [Member] Maximum Schedule of Stock by Class [Table Text Block] Schedule of Common Stock Shares Reserved for Future Issuance Statistical Measurement [Axis] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted-average exercise price, Exercised Prepaid expenses Prepaid Expense, Current Prepaid Expense, Current, Total Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Accrued expenses and other current liabilities Common Stock, Value, Issued Common stock Other Nonoperating Income (Expense) [Abstract] Other income Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility Preferred Stock, Shares Authorized Preferred stock, shares authorized Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Related Party Transaction [Line Items] Entity Registrant Name Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Gross Unrealized Losses Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total Fair value, transfers between level 1, level 2 and level 3 Other Nonoperating Income (Expense) Total other income Subsequent Events [Abstract] KAI-7535 [Member] KAI-7535. KAI-7535 Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Income tax expense (benefit) Measurement Frequency [Axis] Partnership payments Partnership Payments Partnership payments. Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Hengrui License Agreement [Member] Hengrui license agreement. Hengrui License Agreement Deferred Offering Costs Included in Accounts Payable and Accrued expenses Deferred offering costs included in accounts payable and accrued expenses. Deferred offering costs included in accounts payable and accrued expenses Entity Common Stock, Shares Outstanding Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive (loss) income Consolidation Items [Axis] Total assets Assets Weighted-average remaining contractual term (years), Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Income Statement [Abstract] Series A-2 Voting Convertible Preferred Stock [Member] Series A-2 voting convertible preferred stock. Series A-2 Voting Convertible Preferred Stock Stock Issued During Period, Shares, New Issues Number of share issued Temporary Equity, Shares Authorized Preferred stock, shares authorized Accrued manufacturing, Current Carrying amount as of the balance sheet date of current portion of accrued manufacturing expenses. Accrued manufacturing Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Net loss per share attributable to common stockholders - diluted Debt Conversion, Original Debt, Amount Notes settlement value Schedule of Segment Reporting Information, by Segment [Table Text Block] Summary of Expense Categories Reviewed Segments Operating Segments [Member] City Area Code Clinical Deposits Non Current Clinical deposits non current. Non-current clinical deposits Variable Lease, Cost Variable lease costs Dividends, Cash Dividends, Cash, Total Cash dividends Weighted average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Segment Reporting Information [Line Items] Lease, Cost Total lease costs Property, Plant and Equipment, Net Property, Plant and Equipment, Net, Total Property and equipment, net Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation, Total Cash and cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Operating Income (Loss) Loss from operations Retained Earnings [Member] Accumulated deficit Cash and Cash Equivalents [Axis] Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense, Total Weighted average incremental borrowing rate Operating Lease, Weighted Average Discount Rate, Percent Operating Lease, Liability, Noncurrent Operating lease liabilities, non-current Fair Value, Inputs, Level 1 [Member] Fair Value, Inputs, Level 1 Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash used in financing activities Lease, Cost [Table Text Block] Schedule of Lease Costs Investments, Fair Value Disclosure Investments, Fair Value Disclosure, Total Marketable securities Prepaid manufacturing Prepaid Manufacturing Expense Prepaid manufacturing expense. Derivative Contract [Domain] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of Potentially Dilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Corporate Debt Securities [Member] Corporate Debt Securities Debt Securities, Available-for-Sale [Table] Entity Interactive Data Current Statement of Income Location, Balance [Domain] Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Cash flows from operating activities: Accretion of discounts on investments, net Accretion (Amortization) of Discounts and Premiums, Investments Increase (Decrease) in Other Noncurrent Liabilities Other non-current liabilities Entity Tax Identification Number Stock price Share Price Local Phone Number Related Party Transaction [Domain] Accounting Policies [Abstract] Percentage of preferred stockholders at election Debt Instrument, Convertible, Threshold Percentage of Election Preferred Stockholders Debt instrument, convertible, threshold percentage of election preferred stockholders. Increase Decrease In Non-Current Clinical Deposits Increase Decrease In Non-Current Clinical Deposits Non-current clinical deposits Lessee, Operating Lease, Liability, to be Paid, Year Four 2030 Class of Stock [Domain] Commercial Paper [Member] Commercial Paper Labor and Related Expense Personnel related (including stock-based compensation) Personnel related (including stock-based compensation) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Common stock shares available for grant (in shares) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Weighted-average period expected to be recognized Accrued professional services Accrued Professional Fees, Current Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-Term Investments, Total Cash, cash equivalents, and marketable securities Stock, Class of Stock [Table] Entity Emerging Growth Company