v3.26.1
Segment Reporting
3 Months Ended
Mar. 31, 2026
Segment Reporting [Abstract]  
Segment Reporting

14. Segment reporting

The Company operates and manages its business as a single operating segment for the purposes of assessing performance and making operating decisions. The Company’s current focus is on the development of a broad, advanced, and differentiated portfolio of clinical-stage injectable and oral therapies for the treatment of obesity. The Company has one reportable segment. The determination of reportable segments is based on the CODM's use of financial information provided for the purpose of assessing performance and making operating decisions. The Company's CODM is its Chief Executive Officer.

The CODM assesses performance for the segment based on net loss. The measure of segment assets is reported on the balance sheet as total assets.

To date, the Company has not generated any product revenue. The Company expects to continue to incur significant expenses and operating losses for the foreseeable future as it advances product candidates through all stages of development and clinical trials and, ultimately, seeks regulatory approval. As such, the CODM uses cash forecast models in deciding how to invest into the segment. Such cash forecast models are reviewed to assess the entity-wide operating results and performance. Net loss is used to monitor budget versus actual results. Monitoring budgeted versus actual results is used in assessing performance of the segment, along with cash forecast models.

The table below summarizes the expense categories reviewed by the CODM for the three months ended March 31, 2026 and 2025:

 

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

External research and development(1)

 

 

 

 

 

 

Ribupatide injection

 

$

(50,571

)

 

$

(4,469

)

KAI-7535

 

 

(4,483

)

 

 

(374

)

KAI-4729

 

 

(410

)

 

 

(232

)

Ribupatide oral

 

 

(361

)

 

 

-

 

Unallocated research and development and other(2)

 

 

(3,574

)

 

 

(796

)

General and administrative(3)

 

 

(4,417

)

 

 

(3,586

)

Personnel related (including stock-based compensation)(4)

 

 

(20,844

)

 

 

(11,001

)

Interest income

 

 

5,716

 

 

 

1,675

 

Other income (expense), net

 

 

79

 

 

 

800

 

Net loss

 

$

(78,865

)

 

$

(17,983

)

 

1)
External research and development is allocated to the Company’s programs, and includes nonclinical, clinical trial, contract manufacturing, non-employee consultant and contractor, and other research and development costs.
2)
Unallocated research and development includes external costs that are not program specific primarily related to consultant and contractor costs, in addition to research and development allocated rent expense and depreciation.
3)
General and administrative includes external costs related to the Company’s executive, finance, legal, and other administrative functions, such as professional fees for legal, patent, consulting, accounting, audit and tax services. General and administrative also includes information technology costs and general and administrative allocated rent expense and depreciation.
4)
Internal costs includes salaries and related costs, including stock-based compensation, for employees.