0000310158 2026-05-19 2026-05-19 0000310158 1 2026-05-19 2026-05-19 0000310158 2 2026-05-19 2026-05-19 0000310158 3 2026-05-19 2026-05-19 0000310158 4 2026-05-19 2026-05-19 0000310158 5 2026-05-19 2026-05-19 0000310158 6 2026-05-19 2026-05-19 0000310158 7 2026-05-19 2026-05-19 iso4217:USD pure shares S-3 424B5 EX-FILING FEES 333-278066 0000310158 Merck & Co., Inc. N/A N/A S-3 Merck & Co., Inc. false Debt Floating Rate Notes due 2028 true 500000000 500000000.00 0.0001381 69050.00 false Debt 4.300% Notes due 2028 true 1000000000 999600000.00 0.0001381 138044.76 false Debt 4.650% Notes due 2031 true 500000000 499690000.00 0.0001381 69007.19 false Debt 4.950% Notes due 2033 true 1000000000 999300000.00 0.0001381 138003.33 false Debt 5.200% Notes due 2036 true 1500000000 1496640000.00 0.0001381 206685.98 false Debt 5.750% Notes due 2046 true 500000000 498585000.00 0.0001381 68854.59 false Debt 5.850% Notes due 2056 true 1000000000 997610000.00 0.0001381 137769.94 5991425000.00 827415.79 0.00 0.00 827415.79 This registration fee table shall be deemed to update the "Calculation of Filing Fee Tables" in the registrant's Registration Statement on Form S-3ASR (Registration No. 333-278066), originally filed with the Securities and Exchange Commission (the "Commission") on March 19, 2024 and subsequently amended by Post-Effective Amendment No. 1 filed with the Commission on May 14, 2024, in accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended. See note 1. See note 1. See note 1. See note 1. See note 1. See note 1. 5991425000.00 true