75000 - Document - Document and Entity Information
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75010 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS
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75020 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical)
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75030 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
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75040 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSSES
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75050 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSSES 2
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75060 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' DEFICIT
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75070 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' DEFICIT (Parenthetical)
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75080 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
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75090 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical)
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995455 - Disclosure - Organization and Business
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurement
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995485 - Disclosure - Balance Sheet Components
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995495 - Disclosure - Debt - Notes Payable (Details) (calc 2)
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995505 - Disclosure - Related Party Transactions
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995515 - Disclosure - Commitments and Contingencies
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995525 - Disclosure - Debt
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995535 - Disclosure - Warrants
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995545 - Disclosure - Preferred Stock
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995555 - Disclosure - Temporary Equity
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995565 - Disclosure - Stockholders' Deficit
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995575 - Disclosure - Stock-based Compensation
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995585 - Disclosure - Net Loss Per Share
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995595 - Disclosure - Segment Data
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995605 - Disclosure - Subsequent Events
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995615 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995625 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995635 - Disclosure - Fair Value Measurement (Tables)
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995645 - Disclosure - Balance Sheet Components (Tables)
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995655 - Disclosure - Commitments and Contingencies (Tables)
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995665 - Disclosure - Debt (Tables)
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995675 - Disclosure - Warrants (Tables)
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995685 - Disclosure - Preferred Stock (Tables)
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995695 - Disclosure - Stockholders' Deficit (Tables)
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995705 - Disclosure - Stock-based Compensation (Tables)
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995715 - Disclosure - Net Loss Per Share (Tables)
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995725 - Disclosure - Segment Data (Tables)
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995735 - Disclosure - Organization and Business (Details)
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995745 - Disclosure - Organization and Business - Liquidity and Going Concern (Details)
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995755 - Disclosure - Summary of Significant Accounting Policies - Noncontrolling Interest (Details)
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995765 - Disclosure - Summary of Significant Accounting Policies - Variable Interest Entities (Details)
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995775 - Disclosure - Summary of Significant Accounting Policies - Accounts receivable, Accounts payable, Cost of Product Revenue and Concentrations (Details)
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995785 - Disclosure - Summary of Significant Accounting Policies - Inventory (Details)
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995795 - Disclosure - Summary of Significant Accounting Policies - Property and Equipment and Indefinite-lived Intangible Assets (Details)
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995805 - Disclosure - Summary of Significant Accounting Policies - Revenue Recognition (Details)
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995815 - Disclosure - Summary of Significant Accounting Policies - Revenue Recognition - Collaboration Revenue (Details)
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995825 - Disclosure - Summary of Significant Accounting Policies - Comprehensive Loss (Details)
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995835 - Disclosure - Fair Value Measurement - Fair Value of Liabilities Measured on a Recurring Basis (Details)
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995845 - Disclosure - Fair Value Measurement - Estimated Fair Value Asset of Level 3 (Details)
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995855 - Disclosure - Fair Value Measurement - Estimated Fair Value of Level 3 (Details)
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995865 - Disclosure - Fair Value Measurement - Additional Information (Details)
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995875 - Disclosure - Fair Value Measurement - Quantitative Information About The Significant Unobservable Inputs (Details)
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995885 - Disclosure - Fair Value Measurement - Fair Value Option - Hybrid Instruments (Details)
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995895 - Disclosure - Balance Sheet Components - Inventory (Details)
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995905 - Disclosure - Balance Sheet Components - Property and Equipment, Net (Details)
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995915 - Disclosure - Balance Sheet Components - Intangible assets (Details)
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995925 - Disclosure - Balance Sheet Components - Additional Information (Details)
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995935 - Disclosure - Balance Sheet Components - Estimated future amortization expense (Details)
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995945 - Disclosure - Balance Sheet Components - Accrued Liabilities (Details)
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995955 - Disclosure - Related Party Transactions - BOD Cash compensation (Details)
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995965 - Disclosure - Commitments and Contingencies - Commitments (Details)
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995975 - Disclosure - Commitments and Contingencies - Additional Details of Office Space Lease (Details)
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995985 - Disclosure - Commitments and Contingencies - Undiscounted Cash Payment Obligations (Details)
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995995 - Disclosure - Commitments and Contingencies - Undiscounted Cash Payment Obligations (Details) 2
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996005 - Disclosure - Commitments and Contingencies - Undiscounted Cash Payment Obligations (Details) 3
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996015 - Disclosure - Commitments and Contingencies - Purchase Commitment (Details)
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996025 - Disclosure - Commitments and Contingencies - Master Services Agreement (Details)
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996035 - Disclosure - Commitments and Contingencies - Asset Transfer and Transition Commitment Update (Details)
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996045 - Disclosure - Commitments and Contingencies - Revenue Sharing Commitment Update, Joint Venture and Legal Proceedings (Details)
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996055 - Disclosure - Commitments and Contingencies - Joint Venture - Income Statement Information (Details)
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996065 - Disclosure - Commitments and Contingencies - Securities Purchase and Licensing Agreement and April 2024 Agreement for Gelclair (Details)
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996075 - Disclosure - Debt - Notes Payable (Details)
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996085 - Disclosure - Debt - Sale of Future Royalty Interest (Details)
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996095 - Disclosure - Debt - Streeterville Note (Details)
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996105 - Disclosure - Debt - Convertible Notes (Details)
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996115 - Disclosure - Debt - Replacement Notes (Details)
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996125 - Disclosure - Debt - Securities Purchase Agreements and Promissory Notes (Details)
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996135 - Disclosure - Debt - Insurance Financing (Details)
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996145 - Disclosure - Debt - 2019 Tempesta Note (Details)
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996155 - Disclosure - Warrants - Warrants outstanding and exercisable (Details)
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996165 - Disclosure - Warrants - Agreements 2 (Details)
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996175 - Disclosure - Preferred Stock (Details)
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996185 - Disclosure - Preferred Stock - Series K Preferred Stock (Details)
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996195 - Disclosure - Preferred Stock - Series L Preferred Stock (Details)
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996205 - Disclosure - Preferred Stock - Series M Preferred Stock (Details)
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996215 - Disclosure - Preferred Stock - Series N Preferred Stock (Details)
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996225 - Disclosure - Preferred Stock - Series O Preferred Stock (Details)
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996235 - Disclosure - Temporary Equity (Details)
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996245 - Disclosure - Stockholders' Deficit - Reserved shares and Common stock (Details)
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996255 - Disclosure - Stockholders' Deficit - Reverse Stock Split and ATM (Details)
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996265 - Disclosure - Stockholders' Deficit - Noncontrolling Interest (Details)
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996275 - Disclosure - Stock-based Compensation - Summary of Stock Incentive Plans (Details)
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996285 - Disclosure - Stock-based Compensation - Stock-Based Compensation (Details)
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996295 - Disclosure - Stock-based Compensation - 401(k) Plan (Details)
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996305 - Disclosure - Net Loss Per Share - Calculation Of Basic And Diluted Net Loss Per Common Share (Details)
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996315 - Disclosure - Net Loss Per Share - Other Common Stock Equivalents (Details)
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996325 - Disclosure - Net Loss Per Share - Additional Information (Details)
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996335 - Disclosure - Segment Data (Details)
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996345 - Disclosure - Subsequent Events (Details)
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Series O Perpetual Preferred Stock [Member]
Series O perpetual preferred stock.
Series O Perpetual Preferred Stock
Percentage Of Preferred Return On Stated Value Year Three
Percentage of preferred return on stated value year three.
Percentage of preferred return on stated value year three
Aggregate shares issued
Stock Issued During Period, Shares, Issued for Royalty Interest
Number of stock issued in lieu of royalty interest.
Capped percentage of aggregate default
Capped Percentage of Aggregate Default
Capped percentage of aggregate default.
Total shares authorized
Shares Authorized
The maximum number of shares permitted to be issued by an entity's charter and bylaws.
Consideration payable on achievement of milestones
Payments for Services Subject to Achievement of Certain Milestones
Amount of consideration payable on achievement of milestones.
Segments [Domain]
Software
Software
Concentration Risk Type [Axis]
Ending fair value of Level 3 asset (liability)
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis with Unobservable Inputs
Beginning fair value of Level 3 asset (liability)
Entity Incorporation, State or Country Code
Issued
Convertible preferred stock, shares issued (in shares)
Preferred Stock, Shares issued
Balance Sheet Location [Domain]
Beginning fair value of Level 3 liability
Ending fair value of level 3 liability
Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value
Accounts payable
Increase (Decrease) in Accounts Payable
Percentage of default effect
Percentage of Default Effect
Percentage of default effect for each occurrence of default.
Plan Name [Axis]
Entity Current Reporting Status
Probability (as a percent)
Liabilities, Measurement Input Instruments Not Classified As Hybrid
Value of input used to measure liabilities for instruments not classified as hybrid instruments.
Balance Sheet Components [Table]
Balance sheet components.
Payment Of Convertible Notes
Amount of payment of convertible notes.
Payment of Convertible Notes
Operating expenses
Operating Expenses [Abstract]
Weighted Average Stock Option Exercise Price
Weighted Average Stock Option Exercise Price
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Series L Perpetual Preferred Stock
Series L Perpetual Preferred Stock [Member]
Series L perpetual preferred stock.
Finite-Lived Intangible Assets, Amortization Expense, Year Four
2030
Redeemable preferred stock, par value (in dollars per share)
Temporary Equity, Par or Stated Value Per Share
Warrants Expiration Period
Warrants expiration period.
Warrants expiration period
Products and Services [Axis]
Voting rights
Preferred Stock, Voting Rights
Warrants issued in exchange for Royalty Interest
Warrants Issued in Exchange for Royalty Interest
Warrants issued in exchange for Royalty Interest.
Fair Value by Liability Class [Domain]
Document Fiscal Period Focus
The amount of monthly base rent for the first two years.
Monthly Base Rent For First Two Years
Monthly base rent for first two years
Series K
Series K Convertible Preferred Stock [Member]
Series K Convertible Preferred Stock.
Interest rate (as a percent)
Debt Instrument, Interest Rate, Stated Percentage
Revenue
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Outstanding
Redeemable preferred stock, shares outstanding (in shares)
Beginning Balance, Redeemable preferred stock (in shares)
Ending Balance, Redeemable preferred stock (in shares)
Temporary Equity, Shares Outstanding
Other Accrued Liabilities, Current
Accrued other
Total
Convertible Notes Payable Gross
Amount of Convertible notes payable, including unamortized debt discount and debt issuance costs.
Cash
Cash and Cash Equivalent
Derivative Asset [Member]
Derivative asset.
Derivative Asset
Decrease in noncontrolling interest
Noncontrolling Interest, Decrease from Distributions to Noncontrolling Interest Holders
Streeterville Warrants
Streeterville Warrants [Member]
Represents the information pertaining to Streeterville Warrants.
Notes Payable, Current
Notes Payable, Current, Total
Notes payable - current, net
Notes payable, net of discount (includes note designated at Fair Value Option amounting to $18.9 million as of March 31, 2026, and $26.2 million as of December 31, 2025, respectively)
Class Of Warrant Or Right Beneficial Ownership Limitation Percentage
Class Of warrant or right beneficial ownership limitation percentage.
Beneficial ownership limitation
Number of suppliers
Concentration Risk Number Of Suppliers
Represents the number of suppliers as a concentration risk.
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Amount of comparable TDPRV
Tropical Disease Priority Review Voucher Sale Value
The amount of sale value of TRPRV compare sale value.
Beginning On April 2021
Represents information pertaining to period Beginning On April 2021.
Schedule of Short-term Debt [Table]
Asset Class [Domain]
Accumulated impairment
Finite-Lived Intangible Assets, Accumulated Impairment
Accumulated amount of impairment of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.
Indefinite lived intangible assets, net
Statement [Table]
Beginning On October 2021
Represents information pertaining to period Beginning On October 2021.
Present Value of Modified Cash Flows Differed from Original Terms Percentage
Present value of modified cash flows differed from original terms percentage.
Present value of modified cash flows differed from original terms percentage
Series D
Series D perpetual preferred stock
Represents information pertaining to Series D perpetual preferred stock.
Addition to right-of-use assets obtained from new and modified operating liabilities
Recognition of operating lease - right-of-use asset and operating lease liability
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Supplier 3
Supplier Three Member
Supplier 3.
Weighted average grant date fair value of stock options granted (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Global Amendment No 2 To October 2020 Royalty Interest Agreement [Member]
Global Amendment No 2 To October 2020 Royalty Interest Agreement [Member]
Global Amendment No 2 To October 2020 Royalty Interest
Statement
Statement [Line Items]
Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Schedule of reportable segments assets
Segment Reporting, Segment Assets [Table Text Block]
Tabular disclosure of segment assets.
Warrants issued and outstanding
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Other Comprehensive Income (Loss)
Changes in fair value
Entity Filer Category
Beginning On April 1, 2026 [Member]
Beginning On April 1, 2026.
Beginning On April 1 2026
Preferred returns to preferred stockholders
Preferred returns to preferred stockholders
RSUs Outstanding
RSUs Outstanding
Global Amendment No 2 to Royalty Interest October 2020 Purchase Agreement
Global Amendment No 2 to Royalty Interest October 2020 Purchase Agreement [Member]
Represents the information pertaining to Global Amendment No 2 to royalty interest October 2020 purchase agreement.
Liabilities and Equity
Total liabilities and stockholders' deficit
Vehicles [Member]
Vehicles
Debt Instrument [Line Items]
Payables and Accruals [Abstract]
Accrued Expenses
Shortfall restoration period
Accounts Receivable Purchase Agreement, Shortfall Restoration Period
The period within which the difference between the Threshold Price and the amount received under the purchase account (Shortfall) should be repaid under the accounts receivable purchase agreement.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Converted
Fair value measurement with unobservable inputs reconciliation recurring basis liability converted.
Converted
Property, Plant and Equipment, Type [Axis]
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent
Translation adjustments
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Summary of Information About The Company's Consolidated Financial Instruments That Were Measured At Fair Value On A Recurring Basis
Royalty expense Exchange period description
Royalty expense exchange period description.
Royalty Expense Exchange Period Description
Prepaid expenses and other current assets
Prepaid expenses and other current assets
Debt Instrument Unpaid Amount Interest Fees Charges And Late Fees Due Period
Debt instrument unpaid amount interest fees charges and late fees due period.
Debt instrument unpaid amount interest fees charges and late fees due period
Percentage of worldwide revenues
Percentage Of Worldwide Revenues
Percentage of worldwide revenues related to upfront licensing fees and milestone payments from licensees and/or distributors, but specifically excluding licensing fees and/or milestone payments that are reimbursements of clinical trial expenses.
Minimum volume weighted average price of stock
Minimum Volume Weighted Average Price
The minimum volume weighted average price of stock.
Series B
Series B convertible preferred stock
Represents the information pertaining to Series B convertible preferred stock.
Shares Issued, Price Per Share
Purchase price of common stock (per shares)
Shares Issued, Price Per Share
Capitalized costs
Prelaunch Inventory, Capitalized Costs
Amount of prelaunch inventory costs capitalized.
Subsequent Events.
Subsequent Events
Threshold for calculating concentration risk percentage
Threshold Used For Calculating Concentration Of Risk
Threshold used for calculating concentration risk percentage.
Warrants Issued In Exchange For Preferred Stock
Warrants issued in exchange for preferred stock.
Warrants issued in exchange for preferred stock
Royalty Interest August 2020 Purchase Agreement [Member]
Represents information pertaining to Royalty Interest August 2020 Purchase Agreement.
August 2020 Purchase Agreement
Proceeds from Convertible Notes
Proceeds from Convertible Debt
ATM Agreement [Member]
ATM Agreement.
ATM Agreement
Geographical [Domain]
Finished goods
Finished Goods
Royalty and Preferred Stock Exchange Transactions [Member]
Royalty and Preferred Stock Exchange Transactions.
Royalty and Preferred Stock Exchange Transactions
Percentage of preferred return on stated value thereafter
Percentage Of Preferred Return On Stated Value Thereafter
Percentage of preferred return on stated value thereafter.
Series E
Series E perpetual preferred stock
Represents information pertaining to Series E perpetual preferred stocks.
Schedule of inventory
Schedule of inventory
Three major pharmaceutical distributors
Represents the information pertaining to three major pharmaceutical distributors of the entity.
Additional paid-in capital
Additional Paid in Capital, Common Stock
Term for initiation of human trials
Term for Initiation of Human Trials
Term for initiation of human trials.
Percentage of revenue sharing commitment after first million dollars of revenue
Percentage of Revenue Sharing Commitment After the First Million Dollars Revenue
The percentage of revenue sharing commitment after the earning of first million dollars of revenue.
Warrants Issued to in Exchange for Notes Payable and Accrued Interest
Warrants issued to in exchange for notes payable and accrued interest.
Warrants issued in exchange for notes payable and accrued interest
Placement Agent
Placement Agent [Member]
Placement agent.
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Land, Property and Equipment
Property, Plant and Equipment [Line Items]
Incentive stock option term
Share-based Compensation Arrangement by Share-based Payment Award, Terms of Award
Risk free rate
Intangible asset amortization period
Finite-Lived Intangible Asset, Useful Life
Concentration Risk [Table]
Royalty expense first and last exchange period description
Royalty expense first and last exchange period description.
Royalty Expense First and Last Exchange Period Description
Options granted (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Disaggregation of Revenue [Table]
Schedule of calculation of basic and diluted net loss per common share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
March 2021 Purchase Agreement
Represents information pertaining to March 2021 Purchase Agreement.
Other receivable
Increase (Decrease) in Other Receivables
Investment, Name [Axis]
Net loss per share, basic
Net loss per share attributable to common stockholders, basic (in dollars per share)
Earnings Per Share, Basic
Options Available for Grant Under Stock Option Plans [Member]
Options available for grant under stock option plans.
Options available for grant under stock option plans
Issuances
Class of Warrant or Right, Issued
The number of warrants or rights issued during the period.
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax
Translation loss
Translation loss (gains)
Other comprehensive income from translation adjustments
Other comprehensive income from translation adjustments
Option outstanding
Options issued and outstanding
Beginning balance (in shares)
Ending balance (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Supplier Two [Member]
Supplier Two.
Supplier 2
Total current liabilities
Liabilities, Current
Amount of Collateral Requirement Automatically Terminates Once balance of Deposit Account
Amount of collateral requirement automatically terminates once balance of deposit account.
Amount of collateral requirement automatically terminates once balance of deposit account
Napo Therapeutics
Represents information pertaining to Napo Therapeutics.
Accounts receivable
Increase (Decrease) in Accounts Receivable
Lessee, Operating Lease, Liability, to be Paid, Year Five
2030
March 2024 First Insurance Financing
March 2024 First Insurance Financing [Member]
Represents the information pertaining to March 2024 First Insurance Financing.
Inducement options issued and outstanding
Represents information pertaining to inducement stock options.
Payments To Settle Note
Payments to settle note.
Payments to settle note
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Change In The Estimated Fair Value Of Level 3 Liabilities
Fair value
Notes Payable, Fair Value Disclosure
Fair value
Supplier [Axis]
Placement Agent Warrants
Placement Agent Warrants [Member]
Placement agent warrants.
Insurance Retention Amount
Insurance retention amount.
Insurance retention amount
Segment Reconciling Items
Consolidation Items [Domain]
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' deficit
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Change In The Estimated Fair Value Of Level 3 Asset
Sixth Pre-Funded Warrants
Sixth Pre-Funded Warrants [Member]
Sixth Pre-Funded Warrants.
Entity Small Business
Accrued liabilities
Increase (Decrease) in Accrued Liabilities
Notes payable
Basis point for adjustment of discount rate for non-hybrid instruments
Basis Points For Adjustment Of Discount Rate For Non Hybrid Instruments
Basis point for adjustment of discount rate for non-hybrid instruments.
Accumulated deficit
Retained Earnings (Accumulated Deficit)
PIPE Purchase Agreements [Member]
PIPE purchase agreements.
PIPE Purchase Agreements
Non-current notes designated at Fair Value Option
Notes Payable, Non-Current, Fair Value Disclosure
Non-current fair value portion of notes payable.
Restricted Stock, Value, Shares Issued Net of Tax Withholdings
RSUs issued
Preferred Stock
Preferred Stock [Member]
Options cancelled (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period
Carrying Value
Preferred Stock, Value, Outstanding
Standstill Agreement
This member represents standstill agreement.
The amount of monthly base rent due for year three and four.
Monthly Base Rent Due Year Three and Four
Monthly base rent for third and fourth year
Royalty Repayment Amount Reduction Percentage
Royalty repayment amount reduction percentage.
Royalty repayment amount reduction percentage
Warrants - Measurement input
Warrants and Rights Outstanding, Measurement Input
Stock-based Compensation
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
Organization and Business
Principal amount
Royalties Interest, Principal Amount
Principal amount of royalty interest arrangements.
Transaction fee
Payment Of Transaction Fee
The amount of cash outflow for payment of transaction fee under accounts receivable purchase agreement.
Inventory Valuation Reserves
Inventory provisions
Common shares issued to investors in exchange for Preferred Stock
Stock Issued During Period To Investors In Exchange of Preferred Stock
Stock issued during period to investors in exchange of preferred stock.
Deferred revenue recognized as revenue
Contract with Customer, Liability
Contract with Customer, Liability, Total
Financial liability
Amendment Flag
Iliad Warrants
Iliad Warrants [Member]
Represents the information pertaining to Iliad Warrants.
Changes in fair value of freestanding and hybrid financial instruments designated at Fair Value Option
Fair Value Adjustment of Warrants, Conversion Option and Derivative Liability
Amount of expense (income) related to adjustment to fair value of warrants, conversion option and derivative liability.
Products and Services [Domain]
Office space sub lease
Office space sub lease
Represents information pertaining to sub lease of office space.
Modifications to Equity-classified Instruments
Modifications to Equity Classified Instruments
Represents information pertaining to modifications to equity-classified instruments.
October 2020 royalty interest agreements
Represents information pertaining to October 2020 Royalty Interest Agreements.
October 2020 Royalty Interest Agreement
Warrants to purchase shares of Common stock
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Warrants to purchase shares of Common stock
Allowance for inventory obsolescence
Inventory Adjustments
Inventory Adjustments, Total
Accumulated provision for inventory obsolescence
Accumulated provision for inventory obsolescence
Other segment items
Other Segments
Amount of expense for other segment items.
Basic and Diluted Net Loss Per Share of Common Stock
Earnings Per Share, Policy [Policy Text Block]
Concentrations
Concentration Risk [Line Items]
Convertible non-voting common stock
Common stock securities that may be converted to another form of security and do not empower a holder to vote on corporate resolutions or the election of directors.
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Deficit
Percentage of shares issued and outstanding
Percentage of Shares Issued and Outstanding
Percentage of shares issued and outstanding.
Entity Address, Postal Zip Code
Accounts Receivable, net
Accounts Receivable [Policy Text Block]
Summary of warrant activity
Summary of warrant activity
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Total cash provided by (used in) operating activities
Common Stock
Common Stock
Balance Sheet Components [Line Items]
Balance sheet components.
Common And Wainwright Warrants [Member]
Common And Wainwright Warrants.
Common and Wainwright Warrants
Options granted (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
2029
Accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Shares Available for Grant
Share-based Compensation Arrangement by Share-based Payment Award, Shares Available for Grant [Roll Forward]
No definition available.
Debt Instrument, Interest Rate, Effective Percentage
Interest rate
Entity Address, Address Line One
March 2025 Convertible Notes [Member]
March 2025 convertible notes.
March 2025 Convertible Notes [Member]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of estimated grant-date fair value of stock options calculated using the Black-Scholes option-pricing model
Uptown and Streeterville Preferred Stock Exchange Agreements
Uptown and Streeterville Preferred Stock Exchange Agreements [Member]
Uptown and streeterville preferred stock exchange agreements.
Fair Value, Hierarchy [Axis]
Net Loss Per Share
Income Taxes
Income Tax, Policy [Policy Text Block]
Monthly base rent for final 12 months
Monthly Base Rent for Final Months
Represents the amount of monthly base rent for final months.
Beginning Balance, Redeemable preferred stock
Ending Balance, Redeemable preferred stock
Temporary Equity, Carrying Amount, Attributable to Parent
Series O Convertible Preferred stock: $0.0001 par value; 1,557,000 and 0 shares authorized at March 31, 2026 and December 31, 2025, respectively; 1,241,928 and 0 shares issued and outstanding at March 31, 2026 and December 31, 2025
Stock options
An arrangement whereby employees and non-employees are entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. Although there are variations, normally, after vesting, when an option is exercised, the holder pays the strike value in cash to the issuing employer-entity and receives equity shares. The equity shares can be sold into the market for cash at the current market price without restriction. Options may be used to attract, retain and incentivize employees, in addition to their regular salary and other benefits.
Supplemental schedule of cash flow information
Supplemental Cash Flow Information [Abstract]
Foreign Currency Remeasurement and Translation
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Derivative Asset
Derivative Asset, Total
Derivative asset
Royalty Interest Global Amendment Warrants
Royalty Interest Global Amendment Warrants [Member]
Represent the information pertaining to Royal Interest Global Amendment Warrants.
Transfer Of Manufacturing And Supply Agreement Amount
Transfer of manufacturing and supply agreement amount.
Transfer of manufacturing and supply agreement amount
Balance Sheet Location [Axis]
Dividend declared preferred share
Preferred Share Dividend Declared
Preferred share dividend declared.
Investment Type [Axis]
Operating lease - right-of-use asset
Operating Lease, Right-of-Use Asset
Right-of-use asset
Net loss attributable to non-controlling interests
Net loss attributable to noncontrolling interest
Net Income (Loss) Attributable to Noncontrolling Interest
Number of preferred shares surrendered
Number Of Preferred Shares Surrendered
Number of preferred shares surrendered.
At The Market Offering
This member stands for At The Market Offering.
Class of Warrant or Right [Axis]
Document Type
Indefinite-lived Intangible Assets
Goodwill and Intangible Assets, Policy [Policy Text Block]
Type of Arrangement and Non-arrangement Transactions [Axis]
Percentage of ownership interest by parent
Noncontrolling Interest, Ownership Percentage by Parent
Accrued Interest Rate on Royalty
Percentage of accrued interest rate on royalty.
Accrued interest rate on royalty
Arrangements and Non-arrangement Transactions [Domain]
Entity Central Index Key
Expirations and cancelations
Class of Warrant or Right, Subject to Expire
The number of warrants which are subject to expire.
Investors [Member]
Investors.
Investors
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net increase (decrease) in cash and restricted cash
Subsequent Event Type [Domain]
Temporary Equity
Temporary Equity [Text Block]
The entire disclosure for temporary equity.
License and Supply Agreements [Member]
License and Supply Agreements.
License and Supply Agreements
First Insurance Financing
Insurance Financing Non Cash
Represents information pertaining to insurance financing in a non-cash transaction not related to Umbrella insurance.
Total (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Balance Sheet Components
Stock Repurchased and Retired During Period, Shares
Shares retired (in shares)
Percentage of exercise price to offering price
Percentage of exercise price to offering price.
Tempesta Note
Represents the information pertaining to Notes payable.
Master Services Agreement With Integrium LLC, 2020
Master Services Agreement With Integrium LLC, 2020
Represents information relating to Master Services Agreement with Integrium, LLC , 2020.
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Supplier [Domain]
Less: unamortized discount and debt issuance costs
Convertible Notes Payable, Unamortized Discount (Premium) and Debt Issuance Costs, Net
Amount of unamortized debt discount (premium) and debt issuance costs on convertible notes payable.
Operating Lease, Right-of-Use Asset, Amortization Expense
Amortization of operating lease - right-of-use asset
Additional investment from non-controlling interests
Noncontrolling Interest, Increase from Subsidiary Equity Issuance
Additional investment from noncontrolling interests
Goodwill
Weighted Average Remaining Contractual Life (Years)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Finance charge
Debt Related Commitment Fees and Debt Issuance Costs
Series F
Series F perpetual preferred stock
Represents information pertaining to Series F perpetual preferred stocks.
Fair value increase (decrease)
Increase Decrease Liabilities Fair Value Disclosure
Represents increase (decrease) in fair value of financial and nonfinancial obligations.
Pre-Funded Warrants [Member]
Pre-funded warrants, member.
Pre-Funded Warrants
Segment expenses
Segment Expenses
Amount of expenses for segment items.
Sale Proceeds
Sale Proceeds
Represents the information pertaining to sales proceeds.
Options exercised (in shares)
Options exercised (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Debt Disclosure [Abstract]
Basis Points For Adjustment Of Option Adjusted Spread
Basis points for adjustment of option adjusted spread.
Basis point for adjustment of option adjusted spread
PIPE Purchase Agreement
PIPE Securities Purchase Agreement [Member]
Represents the information pertaining PIPE Securities Purchase Agreement.
RSUs Exercised (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Exercised in Period
The number of equity-based payment instruments, excluding stock (or unit) options, that were exercised during the reporting period.
Depreciation and amortization expense
Depreciation Depletion And Amortization Of Property And Equipment
Amount of depreciation depletion and amortization of property and equipment.
Suite 600
Leased Office Premises Suite 600 [Member]
Represents the information pertaining to Leased office premises suite 600.
Common shares issued to third party in exchange of license agreement
Stock Issued During Period, Value, Exchange Of License Agreement
Equity impact of value of new stock issued during the period in exchange for license agreement to third party.
Accrued liabilities
Accrued Liabilities, Current
Total
Minimum monthly royalty repayment amount
Minimum Monthly Royalty Repayment Amount
The amount of minimum monthly repayment of royalty.
Ownership [Domain]
Series J Redeemable Preferred Stock [Member]
Series J Redeemable Preferred Stock.
Series J Redeemable Preferred Stock
Current Fiscal Year End Date
Schedule of Long-term Debt Instruments [Table]
Suite 400
Leased Office Premises Suite 400 [Member]
Represents the information pertaining to Leased office premises suite 400.
Exercises
Class Of Warrant Or Right Exercises
The number of warrants or rights exercised during the period.
Stock Dividends Issued for Preferred Stock
Stock dividends issued for preferred stock.
Stock dividends issued for Preferred Stock
Stock dividends issued as Preferred Stock
Stock dividends issued as Preferred Stock
Document Quarterly Report
Arval Service Lease Italia Spa agreement
Arval Service Lease Italia Spa agreement
Represents information pertaining to Arval service lease italia spa agreement.
Entity Address, State or Province
Restricted stock unit awards issued and outstanding
Beginning balance (in shares)
Ending balance (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Software Developed for Internal Use
Internal Use Software, Policy [Policy Text Block]
Common shares issued from conversion
Stock Issued During Period, Value, Conversion of Convertible Securities
SEED
SEED
Represents information pertaining to Seed Mena Businessmen Services LLC ("SEED").
Investment, Name [Domain]
Fair Value Over (Under) Outstanding Balance
Fair Value, Option, Aggregate Differences, Long-term Debt Instruments
Outstanding
Convertible preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, Shares outstanding
Net comprehensive loss attributable to common stockholders
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Research and Development Expense
Research and Development Expense, Policy [Policy Text Block]
Total
Common Stock, Capital Shares Reserved for Future Issuance
Transaction expense
Transaction Cost
The amount of expenses incurred in connection with transaction cost.
Transaction expense
Class of Warrant or Right [Domain]
Geographical [Axis]
Contract with Customer, Liability, Revenue Recognized
Revenue recognized
Number of kilograms of crofelemer per agreement year
Number Of Kilograms Crofelemer
Represents the number of kilograms of crofelemer per year per agreement.
Shares converted
Conversion of Stock, Shares Converted
Amortization expense.
Amortization Expense
Amortization expense
Total accounts receivable
Raw Material
Raw materials
Non-controlling interest
Stockholders' Equity Attributable to Noncontrolling Interest
Noncontrolling interest
Royalties paid
Payments for royalties
Schedule of common reserved shares of common stock for issuance
Schedule Of Common Stock Reserved For Future Issuance
Represents the tabular disclosure of Common stock reserved for future issuance.
License [Member]
License revenue
License
Fair value increase (decrease) for non-hybrid investments
Increase Decrease Liabilities Fair Value Disclosure For Non Hybrid Investments
Represents increase (decrease) in fair value of financial and nonfinancial obligations for non-hybrid investments.
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Gain or Loss
Percentage of rental rate subject to annual escalations thereafter
Percentage of Rental Rate Subject to Annual Escalations Thereafter
Percentage of rental rate subject to annual escalations thereafter.
Subsequent event
Subsequent Event
Equity Method Investment, Nonconsolidated Investee [Domain]
Series G Preferred Stock
Series G convertible preferred stock
Represents the information pertaining to Series G preferred Stock.
Deferred Revenue, Current
Deferred Revenue, Current, Total
Deferred revenue, current
Additional shares authorized (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized
Percentage of reduction in return bonus
Percentage of Reduction in Return Bonus
Percentage of reduction in return bonus.
Expected life
Purchasers [Member]
Purchasers.
Purchasers
Preferred stock issued in exchange of notes payable and accrued interest (shares)
Preferred Stock Issued During Period, Shares, in Exchange of Notes Payable and Accrued Interest
The number of shares of preferred stock issued during period in exchange of notes payable and accrued interest.
Antidilutive Securities [Axis]
Adjustments to Additional Paid in Capital Increase Decrease in Deemed Dividends
Amount of Increase decrease in additional paid in capital (APIC) resulting from deemed dividend.
Deemed dividend
Interest expense
Interest Expense, Debt
Interest Expense, Debt, Total
Mytesi
This member represents information about Mytesi.
Related Party Transaction [Axis]
Accumulated other comprehensive loss
AOCI Attributable to Parent [Member]
Customer [Domain]
Derivative liability
Derivative Liability
Derivative Liability, Total
Finite-Lived Intangible Assets, Major Class Name [Domain]
Convertible Promissory Notes and Common Stock Warrants [Table]
Disclosure of convertible promissory notes and common stock warrants.
2014 Plan
Represents the information pertaining to 2014 plan of the entity.
Percentage Of Aggregate Number Of Shares Common Stock To Warrants
Percentage of aggregate number of shares common stock to warrants.
Number of common stock shares percentage
Increase (decrease) in Stockholders' Equity (Deficit)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Base rent
Monthly Base Rent
The amount of monthly base rent.
April 2024 Agreement for Gelclair
April 2024 Agreement for Gelclair [Member]
Represents the information relates to April 2024 Agreement for Gelclair.
Thereafter
Finite-Lived Intangible Asset, Expected Amortization, after Year Four
Amount of amortization for asset, excluding financial asset and goodwill, lacking physical substance with finite life expected to be recognized after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).
Not Insider [Member]
Not insider.
Non-Insiders
Woodward
Woodward Member
Woodward.
Preferred stock value
Preferred Stock, Value, Issued
Threshold monthly royalty payment payable
Threshold Monthly Royalty Payment, Payable
Threshold amount of monthly royalty payment payable under the agreement.
Debt Instrument, Maturity Date
Maturity date
Minimum
Minimum
Financial Instrument [Axis]
Current assets:
January 2026 Warrants
January Two Thousand Twenty Six Warrants [Member]
January two thousand twenty six warrants.
Number of royalty interests issued
Number of Outstanding Royalty Interest Issued
Number of royalty interests issued.
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right
Class of warrant shares exchange
Amortization expense
Amortization of Intangible Assets
Specialty Pharmacies
Represents information pertaining to Specialty Pharmacies.
Second Exchange Agreement [Member]
Second exchange agreement.
Second Exchange Agreement
Level 3
Level 3
Liabilities
Liabilities, Fair Value Disclosure [Abstract]
Segment Data
Shares issued in exchange of notes payable and accrued interest (in shares)
Stock Issued During Period, Shares, in Exchange of Notes Payable and Accrued Interest
The number of shares of stock issued during period in exchange of notes payable and accrued interest.
Current liabilities:
Product revenue, net
Description of special one time dividend
Description Of Special One Time Dividend
Description of special one time dividend.
Class of Warrant or Right Exercises Conversions
Class of warrant or right exercises conversions.
Exercises or conversions
Exercises or conversions
Total deposit paid
Operating Lease Deposits Paid
Amount of cash outflow towards payment of operating lease deposits.
Preferred Stock, Convertible, Terms
Preferred stock, convertible, terms
Percentage of Threshold Required for Extinguishment Treatment
Percentage of threshold required for extinguishment treatment.
Percentage of threshold required for extinguishment treatment
Internal use software costs - registry
Internal use software costs - registry
Represents information pertaining to internal use software costs, registry.
Related Party Transactions
Accounts receivable, net
Accounts Receivable, Net, Current
Extension period
Lessee, Operating Lease, Renewal Term
Restricted Cash and Cash Equivalent
Restricted Cash and Cash Equivalent, Total
Restricted cash
Commitments and Contingencies.
Commitments and contingencies (See Note 5)
Minimum Bid Price Requirement Per Share
Minimum bid price requirement per share.
Minimum bid price requirement, per share
Leases
Lessee, Leases [Policy Text Block]
Iliad and Streeterville [Member]
Iliad and Streeterville.
Iliad and Streeterville
Percentage of royalties collected from licenses
Percentage Of Royalties Collected From Licenses
Percentage of royalties collected from licenses.
Work in process
Work in Process
Accrued in-transit payable
Accrued in Transit Payable
Accrued in-transit payable.
General and administrative expense
General and administrative expense
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Noncontrolling Interest
Translation adjustments
Neonorm
Represents information pertaining to sales of Neonorm Calf and Foal.
Total operating lease liability
Lease liabilities
Operating Lease, Liability
Common Warrants [Member]
Common warrants.
Common Warrants
Stockholders' Equity, Reverse Stock Split
Monthly base rent for subsequent twelve months
Monthly Base Rent for Subsequent Twelve Months
Represents the amount of monthly base rent for subsequent twelve months.
Royalty expense last exchange period.
Royalty Expense Last Exchange Period
Restricted Cash, Current
Restricted cash
Bridge Financing
Bridge Loan [Member]
Royalty discount rate
Royalty Discount Rate
Royalty discount rate.
Concentration Risk Benchmark [Axis]
Cash flows from financing activities
Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract]
Royalty Interest Exchange Agreement December 2020 [Member]
Represents the information pertaining to December 2020 Royalty Interest Exchange Agreement.
Napo Therapeutics lease office [Member]
Napo Therapeutics lease office.
Napo Therapeutics Lease Office
Effects of foreign exchange rate changes on assets and liabilities
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
May 2025 First Insurance Financing
May 2025 First Insurance Financing [Member]
May 2025 first insurance financing.
Common stock - non-voting
Common stock - non-voting
Segment net loss
Net loss
Net loss
Net income (loss)
Net income (loss)
Partitioned Royalty
Partitioned Royalty Amount
Amount of partition a new royalty interest in the royalty repayment amount.
Cash Collateral for Borrowed Securities
Cash collateral
Schedule of reconciliation of segments assets to the consolidated assets
Reconciliation of Assets from Segment to Consolidated [Table Text Block]
Number of voting rights entitled for each share of common stock held
Common Stock Voting Rights Number
Represents the number of voting rights entitled for each share of common stock held.
Operating lease liability
Increase (Decrease) In Operating Lease Liabilities
Amount increase (Decrease) in operating lease liabilities.
Weighted-average common stock outstanding, basic
Shares used to compute net loss per common stock, basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Accrued payroll tax
Accrued Payroll Taxes, Current
Scenario [Axis]
Document and Entity Information
Document Information [Line Items]
Fair Value Measurement Inputs and Valuation Techniques Not Classified As Hybrid Instruments [Table Text Block]
Tabular disclosure of input and valuation technique used to measure fair value and change in valuation approach and technique for each separate class of asset and liability measured on recurring and nonrecurring basis for instruments not classified as hybrid instruments.
Summary of Information About The Significant Unobservable Inputs Used In Level 3 Fair Value Measurements For Instruments Not Classified As Hybrid Instruments
Common stock issued upon exercise of restricted stock units
Shares Issued Upon Vesting And Release Of Restricted Stock Units
Value of shares issued upon vesting and release of restricted stock units.
Current notes designated at Fair Value Option
Notes Payable, Current, Fair Value Disclosure
Current fair value portion of notes payable.
Total cost of product revenue
Cost of Goods and Service Benchmark [Member]
Supplier risk
Monthly base rent for first twelve months
Monthly Base Rent for First Twelve Months
Represents the amount of monthly base rent for first twelve months.
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Segments [Axis]
Property, Plant and Equipment, Type [Domain]
Stock Issued During Period, Shares, Reverse Stock Splits
Post reverse stock split number of publicly held shares of common stock
Two Thousand And Twenty Five Streeterville Note [Member]
Two thousand and twenty five streeterville note.
2025 Streeterville Note
Schedule of notes payable
Schedule of Short-term Debt [Table Text Block]
Proceeds from Issuance of Private Placement
Proceeds from Issuance of Private Placement
Increase in royalty repayment, percent
Increase in Royalty Repayment, Percent
The percentage of increase in royalty repayment.
Subsequent Events
Subsequent Events [Text Block]
Series N Perpetual Preferred Stock [Member]
Series N perpetual preferred stock.
Series N Perpetual Preferred Stock
Unpaid balance
Long-term Debt
Jaguar
Jaguar [Member]
Jaguar.
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Cash
Stock-based compensation
Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition
License termination activated upon written notice of material breach of Agreement
License Termination, Threshold Number Of Consecutive Trial Delay Payment Defaults
Number of days agreement can be terminated resulting from a written notice of a material breach.
Convertible preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
J A G X Holdings L L C [Member]
JAGX Holdings, LLC.
JAGX Holdings, LLC
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Work in process, net
Inventory, Work in Process and Raw Materials
Work in process, net
Third Pre-Funded Warrants [Member]
Third Pre-Funded Warrants.
Third Pre-Funded Warrants
Option to extend the lease
Lessee, Operating Lease, Existence of Option to Extend [true false]
Indefinite Lived Intangible Assets Gross Before Impairment
Indefinite lived intangible assets gross before impairment.
Total intangible assets
CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' DEFICIT
Preferred Stock
No definition available.
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Supplier One [Member]
Supplier One.
Supplier 1
Property, Plant, and Equipment, Right of Use Assets, and Intangible Assets [Member]
Property, plant, and equipment, right-of-use assets, and intangible assets.
Property, Plant, and Equipment, Right-of-Use Assets, and Intangible Assets
Carrying value of investment
Equity Method Investments
Finite-Lived Intangible Assets, Amortization Expense, Remainder of Fiscal Year
2026
Series Q Preferred Stock
Series Q Preferred Stock [Member]
Series Q preferred stock.
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Current Expected Credit Losses
Credit Loss, Financial Instrument [Policy Text Block]
Debt instruments maturity period
Debt Instruments Maturity Period
Debt instruments maturity period.
Embedded Derivative, Fair Value of Embedded Derivative Asset
Fair value of embedded derivative
Sales and marketing expense
Minimum Amount Available under Stockholders Equity Requirement by Nasdaq
Minimum amount available under stockholders equity requirement by Nasdaq.
Minimum amount available under stockholders equity requirement by Nasdaq
Fair Value Disclosures [Text Block]
Fair Value Measurement
Modifications to Liability-classified Instruments
Modifications To Liability Classified Instruments
Represents information pertaining to modifications to liability-classified instruments.
Number of remaining commitments of kilograms
Number of Remaining Commitments of Kilograms
Number of remaining commitments of kilograms.
UNITED STATES
US
Warrants
Royalty Interest
Represents the information pertaining to Royalty Interest.
Noncontrolling Interest
Stock Options Outstanding
Stock Options Outstanding
Schedule of Accrued Liabilities [Table Text Block]
Schedule of accrued Liabilities
Debt Instrument, Name [Domain]
Supplemental schedule of non-cash financing and investing activities
Noncash Investing and Financing Items [Abstract]
Discount rate
Discount rate
Share in joint venture's loss
Income (Loss) from Equity Method Investments
Minimum Stockholders Equity Requirement by Nasdaq
Minimum stockholders equity requirement by Nasdaq.
Minimum stockholders equity requirement by Nasdaq
Increase in share reserve based on outstanding number of shares (as a percent)
Percentage of Increase in Share Reserve Based on Outstanding Number of Shares
Represents the percentage of increase in share reserve based on outstanding number of shares.
Semi-annual principal and interest payments
Debt Instrument, Periodic Payment
In process research and development
In process research and development
Plan Name [Domain]
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Gain (Loss) Included in Earnings
Additions
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Settlements
Interest income (expense)
Interest
Interest Expense.
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis
Fair value of liabilities measured on a recurring basis
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity [Domain]
Payment of Tempesta Note
Payment of Tempesta Note
Amount of payment of tempesta note.
Percentage of equity method investment
Equity Method Investment, Ownership Percentage
Offering costs
Cost of Product and Service Sold
Additions
Fair value measurement with unobservable inputs reconciliation recurring basis liability additions.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Additions
Impairment of long lived assets
Impairment, Long-Lived Asset, Held-for-Use
Options exercisable (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Warrant Shares [Member]
Warrant shares.
Warrant Shares
Warrants outstanding, beginning balance
Warrants outstanding, ending balance
Class of Warrant or Right, Outstanding
Warrants outstanding
Leased vehicle
Leased vehicle
Represents information pertaining to leased vehicle.
RSUs granted (in shares)
Share Based Compensation Arrangement, ByShare Based Payment Award, Restricted Stock Units, Available For Grant, Reduced Upon Acquisition
The number of shares under RSU available for grant upon acquisition that were reduced during the reporting period.
New Warrants [Member]
New warrants.
New Warrants
Revised Rental Rate per Rentable Square Foot
Revised rental rate per rentable square foot.
Revised rental rate per rentable square foot
RSUs issued (in shares)
Restricted Stock, Shares Issued Net of Shares for Tax Withholdings
Customer 3
Customer Three Member
Represents the information pertaining to the customer three of the entity.
Related Party [Axis]
Leased office premises
Leased office premises
Represents information pertaining to leased office premises.
Class of Warrant or Right [Table]
Repayment of Unsecured Outstanding Obligations
Repayment of Unsecured Outstanding Obligations
Repayment of unsecured outstanding obligations
Voting Percentage Obtaining to Become Exercisable and Trade Independently
Voting percentage obtaining to become exercisable and trade independently.
Voting percentage obtaining to become exercisable and trade independently
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Net Proceeds From Issuance Of Private Placement
Net proceeds from issuance of private placement.
Net proceeds from issuance of private placement
Preferred Stock, Convertible, Conversion Ratio
Exchange ratio of preferred stock
Entity Address, City or Town
Stock options and RSUs
An arrangement whereby employees and non-employees are entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. Although there are variations, normally, after vesting, when an option is exercised, the holder pays the strike value in cash to the issuing employer-entity and receives equity shares. The equity shares can be sold into the market for cash at the current market price without restriction. Options may be used to attract, retain and incentivize employees, in addition to their regular salary and other benefits.
Stock Options and RSUs
If contracts are terminated within 12 months
If contracts are terminated within 12 months
Represents information pertaining to scenario for termination of lease within 12 months.
Extinguishments
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Extinguishments
Fair value measurement with unobservable inputs reconciliation recurring basis liability extinguishments.
JAGX Holdings [Member]
JAGX holdings member.
JAGX Holdings
Stock Issued During Period Shares To Investors In Exchange Of Preferred stock
Stock issued during period shares to investors in exchange of preferred stock.
Common shares issued to investors in exchange for Preferred Stock (in shares)
Surrender and cancellation of shares
Temporary Equity, Cancellation Of Shares
Number of shares surrendered and cancelled.
Number of reportable segments
Number of Reportable Segments
Number of common stock with dividend rights outstanding
Number Of Common Stock With Dividend Rights Outstanding
Number of common stock with dividend rights outstanding.
Replacement Notes Warrants [Member]
Replacement notes warrants.
Replacement Notes Warrants
Security Exchange Name
Europe
Europe [Member]
Indefinite-Lived Intangible Assets (Excluding Goodwill)
Indefinite lived intangible assets, net
Indefinite lived intangible assets, net
Financing balance
Unpaid Principal Balance
Long-term Debt, Gross
Total property and equipment at cost
Property, Plant and Equipment, Gross
Schedule of convertible preferred stock
Temporary Equity [Table Text Block]
Stock Issued During Period Value Issued For Purchase Agreement
Amount of stock issued in lieu of purchase agreement.
Aggregate shares value
Weighted average interest rate on short-term borrowings
Debt, Weighted Average Interest Rate
Intersegment Eliminations
Accrued share of joint venture losses
Accrued Share of Joint Venture Losses
Accrued share of joint venture losses.
Replacement Notes [Member]
Replacement Notes.
Replacement Notes
Counterparty Name [Axis]
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income tax
Loss before income tax
Income (loss) before income tax expense
Options vested and expected to vest (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Concentration Risk Type [Domain]
Accrued Royalties, Current
Accrued royalties
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Uptown
Uptown Hybrid Instruments [Member]
Represents the information pertaining to Uptown.
Stockholders' Equity
Percentage Of Holding Of Convertible Promissory Note And Warrants
Percentage of holding of convertible promissory note and warrants.
Percentage of holding of convertible promissory note and warrants
Inventory
Inventory, Net
Total inventory, net
Inventory, net
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Cash and restricted cash at end of the period
Cash and restricted cash at beginning of the period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation, Total
Total cash and restricted cash
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activity
Range [Domain]
Exercise price (in dollars per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Total current assets
Assets, Current
Total stock-based compensation expense
Allocated Share-based Compensation Expense
Document Period End Date
Title and Position [Axis]
Fair Value Hierarchy [Domain]
Employer contributions to the plan
Defined Contribution Plan Cost Recognized
Standstill warrants
Standstill Warrants [Member]
Represents the information pertaining to Standstill Warrants.
Impairment of indefinite-lived intangible assets
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)
Impairment
Impairment loss on indefinite-lived intangible assets
Accrued vacation
Accrued Vacation, Current
Purchase Commitment
Long-term Purchase Commitment [Line Items]
Long-term Purchase Commitment
Series A
Series A
Represents the information pertaining to redeemable convertible preferred stock.
Global Amendment No 2 to Royalty Interest August, 2022 Royalty Interest Agreement [Member]
Global Amendment No 2 to Royalty Interest August, 2022 Royalty Interest Agreement [Member]
Global Amendment No 2 to Royalty Interest August, 2022 Royalry Interest
Accrued Salaries, Current
Accrued payroll and commission
Streeterville
Streeterville
Represents the information pertaining to Streeterville Capital, Llc.
CONDENSED CONSOLIDATED BALANCE SHEETS
Restricted stock units issued and outstanding
Restricted Stock Units
Publicly Held Shares Requirement
Publicly held shares requirement.
Publicly held shares requirement
Debt redemption amount
Debt redemption amount.
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Other comprehensive loss attributable to common stockholders
Class of Stock [Axis]
First Exchange Agreement [Member]
First exchange agreement.
First Exchange Agreement
Stock Transactions, Parenthetical Disclosures
Stock Transactions, Parenthetical Disclosures [Abstract]
Streeterville 2022 Royalty Interest Global Amendment No. 4 [Member]
Streeterville 2022 Royalty Interest Global Amendment No. 4 member.
Streeterville 2022 Royalty Interest Global Amendment No. 4
Warrants expiration date
Warrants and Rights Outstanding, Maturity Date
Series B-2
Series B-2 Preferred Stock
Represents the information pertaining to Series B-2 Preferred Stock.
Debt instrument issue discount
Debt Instrument Issue Discount
Debt instrument issue discount.
Total liabilities
Liabilities
Iliad
Iliad Royalty Interest [Member]
Represents the information pertaining to Iliad.
Financial Instruments [Domain]
Timing of Cash Flows
Timing of Cash Flows
Measurement input using timing of cash flows.
Office Space.
Office Space [Member]
Office Space
Percentage of outstanding balance payable elected to prepay
Percentage of Outstanding Balance Payable the Company Elects to Prepay
Percentage of outstanding balance payable on which the company elects to prepay.
Lessee, Operating Lease, Liability, to be Paid, Year Two
2028
Restricted Cash
Restricted Cash, Total
Restricted cash
Aggregate purchase price
Royalty Repayment Amount
The aggregate purchase price of royalty for the entity.
Restricted Stock [Member]
Restricted Stock
Price per share
Exchange Price Per Common Share
Exchange price at rate of per share price of common stock.
Indefinite-lived Intangible Assets, Major Class Name [Domain]
Total intangible assets
Finite-Lived Intangible Assets, Gross
Weighted-average common stock outstanding, diluted
Shares used to compute net loss per common stock, diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Private Investors
Private Investors [Member]
Represents information pertaining to Private investors.
Entity File Number
Animal Health
Represents the information pertaining to animal health segment.
Other assets
Other Assets.
Cover [Abstract]
Measurement Input Type [Axis]
October 2020 Purchase Agreement
Represents information pertaining to Royalty Interest October 2020 Purchase Agreement.
October 2020 Agreement
First Pre-Funded Warrants [Member]
First Pre-Funded Warrants.
First Pre-Funded Warrants
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
RSUs Cancelled (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Brown Stone Capital Limited
Brown Stone Capital Limited [Member]
Brown Stone Capital Limited.
Investments [Domain]
Royalty discount
Discount On Royalty Interest
The amount of discount on royalty discount.
Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Increase in noncontrolling interest
Noncontrolling Interest, Increase from Sale of Parent Equity Interest
Preferred Stock Cancelled and Retired
Preferred stock cancelled and retired.
Preferred stock cancelled and retired
Right to exchange shares at per share price
Temporary Equity, Exchange Shares Issued, Stated Value, Per Share
Per share amount of par value or stated value of per shares of exchange shares issued pursuant to exchange agreement.
Stated value pers share
Bridge Gruber [Member]
Bridge Gruber.
Bridge Gruber
Total net revenue
Scenario, Unspecified [Domain]
Asset Fair value increase (decrease)
Increase (Decrease) Asset Fair Value Disclosure 1
Increase (decrease) asset fair value disclosure.
Number of shares reserved for issuance
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized
Number of Operating Segments
Number of operations segments
Sale of Stock [Domain]
Series H convertible preferred stock
Series H
Series H convertible preferred stock
Represents the information pertaining to Series H convertible preferred stock.
Segment Data
Segment Reporting Disclosure [Text Block]
Streeterville 2
Streeterville Royalty Interest [Member]
Represents the information pertaining to Streeterville royalty interest.
Cash compensation
General and administrative
General and Administrative Expense.
Stock Dividends To Preferred Stockholders
Stock dividends to preferred stockholders.
Stock dividends to preferred stockholders
Cash flows from operating activities
Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract]
License termination term option
Period In Which The License Can Be Terminated If Phase 2 Study Is Not Completed
The period in which the license can be terminated by either party.
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Adjustments to reconcile net comprehensive loss to net cash used in operating activities:
Percentage Of Amount Received To Be Paid To Alivus
Percentage of amount received to be paid to alivus.
Percentage of amount received to be paid to Alivus
Number of options vested (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares
Royalty expense first exchange period
Royalty Expense First Exchange Period
Subsequent Event [Table]
Weighted average fair value of options vested on grant date
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value, Amount
Amount of Weighted average grant-date fair value of options vested.
Represents information pertaining to New employee inducement award plan.
Inducement Award Plan
Inducement Award Plan
Second Pre-Funded Warrants [Member]
Second Pre-Funded Warrants.
Second Pre-Funded Warrants
Shares for royalty exchanged
Stock Issued During Period, Shares, Other
First and Second Pre-Funded Warrants [Member]
First and Second Pre-Funded Warrants.
First and Second Pre-Funded Warrants
Short-Term Debt, Type [Domain]
Finite-lived intangible assets, net
Finite-Lived Intangible Assets, Net
Debt Instrument, Convertible, Conversion Price
Conversion price
Royalty Interest Repayment Amount
Royalty interest repayment amount.
Royalty interest repayment amount
Adjustments to Additional Paid in Capital, Warrant Issued
Warrants issued
Warrants
Warrants issued
Debt
Convertible Promissory Notes and Common Stock Warrants [Line Items]
Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.
Total monthly lease payment, payable in advance
Operating Lease, Expense
Gain (loss) on extinguishment of debt
Gains (Losses) on Extinguishment of Debt
Loss on extinguishment of debt
Loss on extinguishment of debt
Accrued Customer Credits
Accrued customer credits.
Accrued customer credits
Options vested and expected to vest (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted Average Remaining Contractual Life (Years)
Series G Preferred Stock
Series G
Series G Preferred Stock
Represents information pertaining to Series G preferred stock.
Estimated useful lives
Property, Plant and Equipment, Useful Life
Short-Term Debt, Type [Axis]
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Schedule of Undiscounted Cash Payment Obligations
Shares issued
Temporary Equity, Stock Issued During Period, Shares, New Issues
Number of temporary equity issued during the period.
Outstanding common stock equivalents have been excluded from diluted net loss per common share
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Deferred revenue
Contract with Customer, Liability, Current
Stock Issued During Period, Shares, Conversion of Convertible Securities
Common shares issued from conversion (in shares)
Shares issued in exchange of convertible preferred stock
Deemed dividend related to conversion of preferred stock
Deemed Dividend Related To Conversion Of Preferred Stock
Deemed dividend related to conversion of preferred stock.
Ownership [Axis]
Number of major distributors
Concentration Risk, Number of Distributors
The number of major distributors represents the percentage of revenue.
Number of vehicles on lease
Number Of Vehicles On Lease
Number of vehicles on lease.
Repayment of insurance financing
Repayment of Insurance Premium Fee Classified as Financing Activity
The amount of cash outflow for repayment of insurance premium classified as financing activity.
Warrants Exercisable Period
Warrants exercisable period.
Warrants exercisable period
Other receivable
Other Receivables, Net, Current
Warrants
Stock Issued During Period, Value, Warrants
Stock issued during period, value, warrants.
Lease term
Lessee, Operating Lease, Term of Contract
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock with dividend rights outstanding
Less: Operating lease liability, current
Operating lease liability, current
Operating Lease, Liability, Current
Operating lease liability, current
Aggregate shares value
Stock Issued During Period, Value, Issued for Royalty Interest
Amount of stock issued in lieu of royalty interest.
Stockholders' Equity
Collaborative Arrangements and Non-collaborative Arrangement Transactions
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Depreciation and amortization expenses
Depreciation, Depletion and Amortization
Document Transition Report
Operating expenses
Operating Expenses
Operating expenses
Net comprehensive income (loss)
Comprehensive Income (Loss) Net Of Tax Including Portion Attributable To Noncontrolling Interest Deemed Dividends And Stock Dividends To Preferred Stockholders
Comprehensive income (loss) net of tax including portion attributable to noncontrolling interest deemed dividends and stock dividends to preferred stockholders.
Net comprehensive income (loss)
Net comprehensive income (loss)
Research and development
Research and Development Expense.
Sale of products amount
Sale Of Products Amount
Sale of products amount.
Warrants issued and outstanding
Share Based Compensation Arrangement By Share Based Payment Award Warrants Issued And Outstanding Number
No definition available.
Cost of revenue
Cost of product revenue
Cost of Revenue
Streeterville New Note [Member]
Streeterville new note.
Streeterville New Note
Series M Preferred Stock
Series M Preferred Stock [Member]
Series M Preferred Stock.
Series M
Preferred stock issued in exchange of notes payable and accrued interest
Preferred Stock Issued During Period in Exchange of Notes Payable and Accrued Interest
Preferred stock issued during period in exchange of notes payable and accrued interest.
Concentrations
Concentration Risk, Policy [Policy Text Block]
Disclosure of accounting policy for concentrations risk of the entity.
Additional royalty financings committed
Additional Royalty Financings Committed
The amount of additional royalty financings committed.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
Preferred stock voting power cap
Preferred Stock Voting Power Cap
Preferred stock voting power cap
Non-refundable license fee
Non-refundable license fee.
Non-refundable License Fee
Agreement term
Term of Agreement
Term of agreement from the effective date.
Aggregate offering price
Issuance of common stock
Stock Issued During Period, Value, New Issues
Fifth Pre-Funded Warrants [Member]
Fifth Pre-Funded Warrants.
Fifth Pre-Funded Warrants
Summary of incentive plan activity
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
Number of specialty pharmacies.
Number Of Specialty Pharmacies
Number of specialty pharmacies.
Assets, Fair Value Disclosure [Abstract]
Assets
December 2020 Purchase Agreement
December 2020 Purchase Agreement
Represents information pertaining to Royalty Interest December 2020 Purchase Agreement.
Net change in the fair value
Fair Value, Option, Changes in Fair Value, Gain (Loss)
Derivative Asset, Statement of Financial Position [Extensible Enumeration]
Stockholders' Equity Note Disclosure [Text Block]
Stockholders' Deficit
Canalevia-CA1
This member represents information about Canalevia.
Intangible assets
Finite-Lived Intangible Assets [Line Items]
Net Loss Per Share
Earnings Per Share [Text Block]
Royalty Repayment Amount Balance
Royalty repayment amount balance.
Royalty repayment amount balance
Temporary Equity
Temporary Equity [Line Items]
Beginning Balance (in shares)
Ending Balance (in shares)
Shares, Issued
Additional shares issued to satisfy accrued preferred returns
Additional Shares Issued to Satisfy Accrued Preferred Returns
Additional shares issued to satisfy accrued preferred returns.
Magdalena Biosciences, Inc.
Magdalena Biosciences, Inc. [Member]
Represents information pertaining to Magdalena Biosciences, Inc.
Probability (as a percent)
Liabilities, Measurement Input
Value of input used to measure liabilities.
Computers and peripherals
Computers and peripherals
Net loss attributable to common stockholders
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Noncontrolling Interest [Abstract]
Other comprehensive loss attributable to non-controlling interests
Other comprehensive loss attributable to noncontrolling interests
Inventory
Increase (Decrease) in Inventories
fair value of warrants
Fair Value of Warrants
Fair value of warrants.
Prelaunch Inventory
Prelaunch Inventory, Policy [Policy Text Block]
Disclosure of prelaunch inventory accounting policy for inventory classes, including, but not limited to, basis for determining inventory amounts, methods by which amounts are added and removed from inventory classes, loss recognition on impairment of inventories, and situations in which inventories are stated above cost.
Knight
Represents information about distribution, license and supply agreement with Knight Therapeutics, Inc.
Term of warrant
Warrants and Rights Outstanding, Term
The amount of monthly base rent due for year seven and eight.
Monthly Base Rent Due Year Seven and Eight
Monthly base rent for seventh and eighth year
Total intangible assets, net
Intangible assets, net
Intangible Assets, Net (Excluding Goodwill)
Proceeds From Cost Associated With Issuance Of Common Stock Through Stock Purchase Agreement
The cash outflow for payment of common stock issuance costs through stock purchase agreement.
Proceeds from issuance of shares in At the Market offering, net of issuance and offering costs of $0 and $17 in 2026 and 2025, respectively
Accrual for Taxes Other than Income Taxes, Current
Accrued local tax
Class Of Warrant Or Right Board Redemption Rights Price Per Stock Purchase Right
Class of warrant or right board redemption rights price per stock purchase right.
Redemption price per right
Cash paid for operating lease liabilities recognized under operating cash flows
Operating Lease, Payments
2013 Plan
Represents information pertaining to 2013 plan of the entity.
Assets
Assets [Abstract]
Beginning On September 2023
Represents information pertaining to period Beginning On September 2023.
December 2021 ATM Agreement
This member stands for December 2021 At The Market Offering Agreement.
Streeterville Note
Streeterville Note
Represents the information pertaining to Streeterville Note.
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Document Fiscal Year Focus
Uptown Common Stock Exchange Agreements [Member]
Uptown Common Stock Exchange Agreements.
Uptown Common Stock Exchange Agreements
Redeemable preferred stock
Increase (Decrease) in Temporary Equity [Roll Forward]
Common stock issued in exchange of debt
Debt Conversion, Converted Instrument, Shares Issued
Conversion Shares
Concentration Risk Benchmark [Domain]
March 2025 First Insurance Financing [Member]
March 2025 first insurance financing.
March 2025 First Insurance Financing
Beginning On September 2022
Represents information pertaining to period Beginning On September 2022.
Accounts payable
Accounts Payable, Current
Two Thousand And Twenty One Streeterville Note [Member]
Two thousand and twenty one streeterville note.
2021 Streeterville Note
Common shares issued to third party in exchange of license agreement (in shares)
Stock Issued During Period, Shares, Exchange Of License Agreement
Number of new stock issued during the period in exchange for license agreement to third party.
Research and development expense
Percentage of net sales
Percentage Of Net Sales Of Trademark
Percentage of net sales of trademark.
Represents information pertaining to New Employee Inducement Award Plan.
2020 New Employee Inducement Award Plan
2020 New Employee Inducement Award Plan
Other assets
Increase (Decrease) in Other Noncurrent Assets
Convertible Notes Payable [Member]
Convertible Promissory Notes
Convertible Notes
Asset Measurement Input
Asset measurement input.
Probability (as a percent)
Deferred Revenue
Deferred Revenue, Total
Deferred revenue
Amount of chargebacks and discounts, expected due within one year or the normal operating cycle, if longer.
Accrued Chargebacks And Discounts
Accrued chargebacks and discounts
Payments made to date to SEED
Payments Made to Date to SEED
The payments made till date to SEED.
Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months
2027
Series B-1
Series B-1 Preferred Stock
Represents the information pertaining to Series B-1 Preferred Stock.
Series I convertible preferred stock
Series I
Series I convertible preferred stock
Represents the information pertaining to Series I convertible preferred stock.
Fair Value
Fair Value Measurement, Policy [Policy Text Block]
Irving
Irving Park Capital, LLC [Member]
Represents information pertaining to Irving Park Capital, LLC.
Proceeds exceeding amount from financing or business development transaction to repay debt
Proceeds exceeding amount from financing or business development transaction to repay debt.
Temporary Equity
Temporary Equity Disclosure [Abstract]
Options vested, exercisable and expected to vest
No definition available
Shares of common stock reserved for issuance
Common Stock Reserved For Future Issuance Abstract
Fair Value Measurement
Basis point for adjustment of discount rate
Basis Points for Adjustment of Discount Rate
Basis point for adjustment of discount rate.
Commitments and Contingencies
Threshold price
Accounts Receivable Purchase Agreement, Threshold Price
The amount of threshold price under the accounts receivable purchase agreement.
Until One Year Anniversary
Represents information pertaining to until one year anniversary.
Lessee, Operating Lease, Liability, to be Paid, Year One
2027
license fees recognized
Proceeds from License Fees Received
Total net proceeds
Sale of Stock, Consideration Received on Transaction
Net loss attributable to common stockholders
Net loss attributable to common stockholders (basic)
Net Income (Loss) Available to Common Stockholders, Basic
Net loss attributable to common stockholders
May 2024 First Insurance Financing
May 2024 First Insurance Financing [Member]
Represents the information pertaining to May 2024 First Insurance Financing.
Debt Instrument [Axis]
Clinical Trial Accruals
Clinical Trial Accruals [Policy Text Block]
Disclosure of accounting policy for clinical trial accruals.
Fair value of IPR&D assets
Fair Value of Assets Acquired
Stock-based Compensation
Unrecognized stock-based compensation expense
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized
Assets, Fair Value Disclosure
Total fair value of assets
Sale of Stock [Axis]
Derivative Instrument
Derivatives, Policy [Policy Text Block]
Concentration risk (as a percentage)
Concentration Risk, Percentage
Liquidation Preference per Share
Temporary Equity, Liquidation Preference Per Share
Mandatory prepayments of outstanding balance percentage
Mandatory prepayments of outstanding balance percentage.
Indefinite-Lived License Agreements
Carrying amount of license
Fair value of notes
Debt Instrument, Fair Value Disclosure
Liability Classified Preferred Stock Policy Text Block
Liability classified preferred stock.
Liability-Classified Preferred Stock
External revenue
Total revenue, net
Revenue
Revenues, Total
Beginning On March 2024
Represents information pertaining to period Beginning On March 2024.
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Adjustments to Additional Paid in Capital, Warrant Issued, Shares
Adjustments to additional paid in capital, warrant issued, shares.
Warrants issued (in shares)
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Payments To Settle Convertible Notes
Payments to settle convertible notes.
Payments to settle convertible notes
Options cancelled (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Gen Ilac Ve Saglik Urunleri Sanayi Ve Ticaret, A.S
Gen Ilac Ve Saglik Urunleri Sanayi Ve Ticaret, A.S
Represents information pertaining to Gen Ilac Ve Saglik Urunleri Sanayi Ve Ticaret, A.S.
Gen
Customer 1
Represents the information pertaining to the customer one of the entity.
Related Party [Domain]
Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table]
Redeemable preferred stock, shares issued (in shares)
Temporary Equity, Shares Issued
Napo [Member]
Napo.
Napo
Class of Warrant or Right [Line Items]
Class of warrant or right, exercisable.
Class of Warrant or Right, Exercisable
Warrant exercisable
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Accounts Payable [Member]
Total accounts payable
Patents
Patents
Remainder of 2024
Lessee, Operating Lease, Liability, Payments, Remainder of Fiscal Year
2026
Document Information [Table]
Legal Entity [Axis]
Changes in assets and liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Property, Plant and Equipment [Table Text Block]
Schedule of property and equipment, net
Beginning balance (in dollars per share)
Ending balance (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Preferred Stock
Preferred Stock [Text Block]
Fair Value Measurements, Recurring and Nonrecurring [Table]
May 2023 First Insurance Financing
Represents the information pertaining to May 2023 First Insurance Financing.
Additional paid-in capital
Inventory
Inventory, Gross [Abstract]
Stockholder Rights Plan
Stockholder Rights Plan [Member]
Stockholder rights plan.
The number of shares under options available for grant upon acquisition that were reduced during the reporting period.
Share Based Compensation Arrangement by Share Based Payment Award Options Available for Grant Reduced Upon Acquisition
Options granted (in shares)
Common stock issued to other third party for services
Stock Issued During Period, Value, Issued for Services
Fair Value, Measurement Frequency [Domain]
Iliad
Represents information pertaining to Iliad capital.
Income Statement Location [Axis]
Cash received in the settlement
Cash Received In The Settlement
Cash received in the settlement as per agreement.
Payment of insurance financing
Payment of Insurance Financing
Payment of insurance financing.
Transfer price receivable upon achievement of certain regulatory and sales milestones
Receivable upon Achievement of Certain Regulatory and Sales Milestones
The amount receivable for all licensed products upon achievement of certain regulatory and sales milestones
Trading Symbol
Shares designated
Convertible preferred stock, shares designated (in shares)
Preferred Stock, Shares Designated
The number of shares designated of the maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws.
Schedule of Finite-Lived Intangible Assets [Table]
Schedule of Related Party Transactions, by Related Party [Table]
Increase (Decrease) In Fair Value Of Convertible Debt
Increase (decrease) in fair value of convertible debt.
Change in fair value of Convertible note
Proceeds from Notes Payable
Proceeds from Notes Payable, Total
Cash received from notes
Extinguishment of Debt [Axis]
Board of directors
Board of directors
Cash and Restricted Cash Policy Text Block
Disclosure of Cash and Restricted Cash.
Cash and Restricted Cash
Securities purchase agreement
Securities Purchase Agreement
Represents the information relates to Securities Purchase Agreement.
Subsequent Event Type [Axis]
Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued Legal Costs
Accrued legal costs
Schedule of intangible assets
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Common stock - voting
Common stock securities that do empower a holder to vote on corporate resolutions or the election of directors.
Series C
Series C perpetual preferred stock
Represents information pertaining to Series C perpetual preferred stocks.
Recurring
Series O Convertible Preferred Stock [Member]
Series O Convertible Preferred Stock.
Series O Convertible Preferred Stock
Total undiscounted operating lease payments
Lessee, Operating Lease, Liability, Payments, Due
Preferred Stock Liquidating Preference
Preferred stock liquidation preference per share
Imputed interest expenses
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Fair Value Measurement Inputs and Valuation Techniques
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Sales and marketing
Selling and Marketing Expense.
Agreement extension term
Collaboration Agreement Extension Term
Extension term of collaboration agreement.
License agreement term (in years)
Collaboration Agreement, Term
The period of collaboration agreement.
Number of distribution agreements
Number of Distribution Agreements
The number of distribution agreements.
Equity Components [Axis]
Options exercisable (in years)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term
Exchanges
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Exchanges
Amount of exchanges of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.
Equity Component [Domain]
Summary of stock-based compensation expense
Schedule of Share-based Compensation, Activity [Table Text Block]
Asset Class [Axis]
Maturity date
Maturity Date
Maturity date.
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Deferred revenue, noncurrent
Fourth Pre-Funded Warrants [Member]
Fourth Pre-Funded Warrants.
Fourth Pre-Funded Warrants
RSUs vested and released (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested And Released
The number of equity-based payment instruments, excluding stock (or unit) options, that were vested and released during the reporting period.
RSUs vested and released (in shares)
Common stock issued upon exercise of restricted stock units (in shares)
Shares Issued Upon Vesting And Release Of Restricted Stock Units, Shares
Number of shares issued upon vesting and release of restricted stock units.
Number of promises.
Number Of Promises
Number of promises
The Maximum Amount To Be Received By Alivus
The maximum amount to be received by Alivus.
Maximum amount to be received by Alivus
Redeemable preferred stock
Redeemable Preferred Stock [Member]
Beginning On October 2022
Represents information pertaining to period Beginning On October 2022.
The amount of monthly base rent due for year five and six.
Monthly Base Rent Due Year Five and Six
Monthly base rent for fifth and sixth year
Woodward and Future Pak
Woodward and Future Pak [Member]
Woodward and future pak.
Customer [Axis]
Notes payable - non-current, net
Notes Payable, Noncurrent
Notes payable, net of discount, net of current portion (includes notes designated at Fair Value Option amounting to $7.6 million as of March 31, 2026, and $5.7 million as of December 31, 2025, respectively)
Series N Preferred Stock [Member]
Series N preferred stock.
Series N Preferred Stock
Series N
Collaboration Revenue
Collaborative Arrangement, Accounting Policy [Policy Text Block]
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSSES
Beginning On April 2022
Represents information pertaining to period Beginning On April 2022.
Equity Method Investment, Nonconsolidated Investee [Axis]
Redeemable preferred stock, designated from authorized preferred stock
Temporary Equity Shares Designated
The number shares designated of the maximum number of temporary equity shares permitted to be issued by an entity's charter and bylaws.
Maximum
Maximum
Impairment of Intangible Assets (Excluding Goodwill)
Impairment of Intangible Assets (Excluding Goodwill), Total
Impairment loss on indefinite-lived intangible assets
Impairment loss on intangible assets
upfront revenue and royalties
Upfront revenue and royalties.
Upfront revenue and royalties
Notes designated at Fair Value Option
Liabilities, Fair Value Disclosure, Recurring
Total fair value of liabilities
Additions
Range [Axis]
Contract with Customer, Liability, Noncurrent
Deferred revenue, net of current portion
Uptown Park Capital, LLC
Uptown Park Capital, LLC
Represents information relating to Uptown Park Capital, LLC.
Accumulated amortization
Finite-Lived Intangible Assets, Accumulated Amortization
Global Amendment No 2 to Royalty Interest December, 2020 Purchase Agreement
Global Amendment No 2 to Royalty Interest December, 2020 Purchase Agreement [Member]
Represents the information pertaining to Global Amendment No 2 to royalty interest December 2020 purchase agreement.
Common Stock, Value, Issued
Common stock value
Carrying value of notes
Convertible Notes, Carrying Amount
The amount of carrying value of convertible notes.
Net loss attributable to common stockholders (diluted)
Net Income (Loss) Available to Common Stockholders, Diluted
Cash and Cash Equivalents [Abstract]
Cash and restricted cash
Principles of Consolidation
Consolidation, Policy [Policy Text Block]
Beginning Balance
Ending Balance
Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest
Total stockholders' deficit
Equipment
Common stockholders:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Exchanges
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Settlements
Preferred Stock Dividends, Income Statement Impact
Deemed dividend to preferred stockholders
Long-lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Percentage Of Preferred Return On Stated Value Year Two
Percentage of preferred return on stated value year two.
Percentage of preferred return on stated value year two
Other Risks and Uncertainties
Other Risks and Uncertainties [Policy Text Block]
Disclosure of accounting policy for other risks and uncertainties.
Schedule of estimated future amortization expense of intangible assets with finite lives
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Uptown 2020 Royalty Interest Global Amendment No. 4 [Member]
Uptown 2020 Royalty Interest Global Amendment No. 4 member.
Uptown 2020 Royalty Interest Global Amendment No. 4
Pre Funded Warrants [Member]
Pre funded warrants.
Pre-funded Warrants
Pre Funded Warrants
Summary of Significant Accounting Policies [Table]
Summary of Significant Accounting Policies.
Shares Authorized
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Accrued Interest
Interest Payable, Current
Royalties incurred
Royalty Expense
Royalty expense
Comprehensive Income (Loss), Net of Tax, Attributable to Noncontrolling Interest
Net comprehensive loss attributable to noncontrolling interests
Debt outstanding balance
Debt Instrument, Debt Default, Amount
Total operating expenses
Costs and Expenses
Percentage of return bonus payable
Percentage of Return Bonus Payable
Percentage of return bonus payable.
Finite-Lived Intangible Assets by Major Class [Axis]
Related party Transactions
Related Party Transaction [Line Items]
Entity Registrant Name
Debt
Debt Disclosure [Text Block]
Customer risk
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Finite-Lived Intangible Assets, Amortization Expense, Year Two
2028
Changes in fair value of freestanding and hybrid financial instruments designated at Fair Value Option
Fair Value Adjustment of Financial Instruments and Hybrid Instrument Designated at Fair Value of Option
The amount of fair value adjustments of financial instruments and hybrid instrument designated at fair value of option.
Other Nonoperating Income (Expense)
Other income (expense)
Represents the information pertaining to two major pharmaceutical distributors of the entity.
Two major pharmaceutical distributors
Global Amendment No 2 to Royalty Interest August, 2022 Purchase Agreement
Global Amendment No 2 to Royalty Interest August, 2022 Purchase Agreement [Member]
Represents the information pertaining to Global Amendment No 2 to Royalty Interest August, 2022 Purchase Agreement.
Royalty interest amount
Royalty Interests
The amount of royalty interest, treated as debt.
Series L
Series L Preferred Stock [Member]
Series L Preferred Stock.
Series L Preferred Stock
Subsequent Events
Umbrella Insurance Financing
Represents the information pertaining to Umbrella Insurance Financing.
Accounts Receivable Purchase Agreement
Represents the information pertaining to accounts receivable purchase agreement.
Finite-Lived Intangible Assets, Amortization Expense, Year Three
2029
Income tax expense
Income tax expense
Income Tax Expense (Benefit)
Measurement Frequency [Axis]
Beginning on March 2021
Represents the information pertaining to period beginning on March, 2021.
Gross proceeds from the issuance of common stock
Proceeds from issuance of Common stock
Net proceeds
Payment of 2025 Note Payable
Payment of Note Payable
c
Stock-based Compensation
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Summary of Information About The Significant Unobservable Inputs Used In Level 3 Fair Value Measurements
Amount of exchange of outstanding balance in royalty interest
Exchange Of Outstanding Balance In Royalty Interest
Represents the amount of exchange of outstanding balance in royalty interest.
Percentage of ownership interest by non-controlling owners
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners
Entity Common Stock, Shares Outstanding
Aggregate shares of common stock
Liability Class [Axis]
Aggregate shares issued
Stock Issued During Period Shares Issued For Purchase Agreement
Number of stock issued in lieu of purchase agreement.
Series J Perpetual Preferred Stock
Series J Perpetual Preferred Stock [Member]
Represents information relating to Series J perpetual preferred stock.
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Consolidation Items [Axis]
Percentage Of Preferred Return On Stated Value Year One
Percentage of preferred return on stated value year one.
Percentage of preferred return on stated value year one
Series J convertible preferred stock
Series J Preferred Stock
Series J Preferred Stock [Member]
Represents information relating to Series J preferred stock.
Number of shares to be exchanged
Number of Common Stock to be Issued in Exchange of Portioned Royalty
Number of common stock in exchange for portioned royalty.
Amount of Funds in Deposit Account Exceed Collateral Requirement
Amount of funds in deposit account exceed collateral requirement.
Amount of funds in deposit account exceed collateral requirement
Percentage of revenue sharing commitment
Percentage of Revenue Sharing Commitment
The percentage of revenue sharing commitment.
Uptown Exchange Agreement [Member]
Uptown exchange agreement.
Uptown Exchange Agreement
RSUs Granted (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period
Percentage of gross proceeds received from return
Percentage of Gross Proceeds Received from Return Bonus
Percentage of gross proceeds received from the sale of Tropical Disease Priority Review voucher, the return bonus.
Temporary Equity, by Class of Stock [Table]
Total assets
Segment assets
Assets
Inventory, Policy [Policy Text Block]
Inventory, net
Property and Equipment [Table]
Property, Plant and Equipment [Table]
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
After One Year Anniversary
Represents information pertaining to after one year anniversary.
Interest accrued.
Interest Accrued
Interest accrued
Warrants
Warrants, Fair Value Disclosure
Fair value portion of warrants classified as equity.
Fair Value Option
Fair Value of Financial Instruments, Policy [Policy Text Block]
Stock-based Compensation
Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block]
Weighted average
Weighted average
Number of shares issued
Sale of Stock, Number of Shares Issued in Transaction
Global Amendment No 2 To October 2020 Purchase Agreement [Member]
Global amendment no 2 to October 2020 purchase agreement.
Global Amendment No 2 To October 2020 Purchase Agreement
Issuance of common stock (in shares)
Stock Issued During Period, Shares, New Issues
Shares issued after balance sheet date
Redeemable preferred stock, shares authorized (in shares)
Temporary Equity, Shares Authorized
Initial term of contract
Initial Term of Contract
The initial period of contract.
RSUs Vested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Manufacturing and Supply Agreement with Alivus [Member]
Represents the information pertaining to manufacturing and supply agreement (the "Agreement") with with Alivus.
Manufacturing and Supply Agreement with Alivus
Number of accredited investors
Number of accredited investors.
Net loss per share, diluted
Net loss per share attributable to common stockholders, diluted (in dollars per share)
Earnings Per Share, Diluted
Insider [Member]
Insider.
Insiders
Insider
Schedule of reportable segments net revenue and net loss
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of reportable segments' net revenue and net loss
Operating Segments
Long-term Purchase Commitment [Table]
Deposit Account [Member]
Lakeside Bank Account
Title and Position [Domain]
Disaggregation of Product Revenue
Disaggregation of Revenue [Abstract]
Schedule Of Summarized Income Statement Information Using Equity Method [Table Text Block]
Tabular disclosure of summarized income statement information using equity method.
Schedule of Summarized Income Statement Information Using Equity Method
City Area Code
Description of Nasdaq Notification Related to Reverse Stock Split
Description of nasdaq notification related to reverse stock split.
Description of Nasdaq notification related to reverse stock split
Fair Value Option, Disclosures [Table Text Block]
Summary of The Fair Value And Unpaid Principal Balance For Items The Company Accounts For Under FVO
Series O Preferred Stock
Series O Preferred Stock [Member]
Series O Preferred Stock.
Number of plant extracts
Number of Plant Extracts
Number of plant extracts.
Warrants
Class Of Warrants Disclosure [Text Block]
The entire disclosure for information about different class of warrants.
Changes in fair value
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Period Increase (Decrease)
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Period Increase (Decrease), Total
Other Comprehensive Income (Loss), Net of Tax
Other comprehensive loss
The amount of monthly base rent due for year nine.
Monthly Base Rent Due Year Nine
Monthly base rent for ninth year
Insurance Financing
Represent the information relating to the Insurance Premium Financing
Principal amount
Debt Instrument, Face Amount
Aggregate principal amount
Collaboration revenue
Collaboration Revenue Net
Represents the amount pertains to recognition of collaboration revenue for the period
August 2022 Purchase Agreement
Represents the information pertaining to August 2022 Purchase Agreement.
Purchase Agreement
Represents the information pertaining to royalty interest purchase agreement.
Counterparty Name [Domain]
Measurement Input, Credit Spread [Member]
Adjusted Spread
Manufacturing and Supply Agreement with Glenmark Life Sciences Limited
Manufacturing and Supply Agreement with Glenmark Life Sciences Limited [Member]
Represents the information pertaining to manufacturing and supply agreement (the "Agreement") with Glenmark Life Sciences Limited.
Weighted-average remaining life (years)
Operating Lease, Weighted Average Remaining Lease Term
Segment Information
Segment Reporting Information [Line Items]
Reverse stock split ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Accredited Investors
Investor [Member]
Lease costs
Lease, Cost
Debt
Debt and warrants abstract
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
March 2026 First Insurance Financing [Member]
March 2026 first insurance financing.
March 2026 First Insurance Financing
The amount of amended monthly base rent for the remaining term.
Monthly Base Rent, Remaining Term
Monthly base rent for remaining term
Options exercisable (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Operating Income (Loss)
Income (loss) from operations
Accumulated deficit
RSUs exercised
Share Based Compensation Arrangement, By Share Based Payment Award, Restricted Stock Units, Available For Grant, Exercised
The number of shares under RSU available for grant that were exercised during the reporting period.
RSUs exercised
Supplier Four Member
Supplier 4.
Supplier 4
Stock-based compensation, vested and released restricted stock units, and exercised stock options
Share-based Compensation
Preferred stock issued on preferred returns of Series M Preferred Stock (in shares)
Preferred Stock Issued on Preferred Returns of Series M Preferred Stock
Preferred stock issued on preferred returns of series m preferred stock.
Volatility
Issuance costs
Payments of Stock Issuance Costs
Share-based Compensation Arrangement by Share-based Payment Award, Options Available for Grant, Forfeitures in Period upon Initial Public Offering
Options cancelled (in shares)
The number of shares under options available for grant upon initial public offering that were cancelled during the reporting period.
Series K Preferred Stock
Series K Preferred Stock [Member]
Series K preferred stock
Lessee, Operating Lease, Additional Details [Table Text Block]
Tabular disclosure of lessee operating lease additional details.
Schedule of Additional Details of Office Space Lease
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease liability, net of the current portion
Operating lease liability, net of current portion
Operating Lease, Liability, Noncurrent
Stockholders' Equity
Class of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Total cash provided by (used in) financing activities
Notes payable
Notes payable, net of discount
Notes Payable.
Short-term Debt [Line Items]
Series M Perpetual Preferred Stock
Series M Perpetual Preferred Stock [Member]
Series M perpetual preferred stock.
Eliminations And Reconciling Items [Member]
Represents the aggregate total of reconciling items and elimination items.
Developed technology
Developed technology
Extinguishment of Debt, Type [Domain]
Beginning On March 2023
Represents information pertaining to period Beginning On August 2022.
Derivative Liability, Noncurrent
Derivative liability
Schedule of Goodwill [Table]
Shares issued in exchange of notes payable and accrued interest
Stock Issued During Period in Exchange of Notes Payable and Accrued Interest
Stock issued during period in exchange of notes payable and accrued interest.
License Agreement
Represents information pertaining to the license agreement.
Grant [Member]
Grant revenue
Customer 2
Represents the information pertaining to the customer two of the entity.
Schedule of other common stock equivalents
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Entity Interactive Data Current
Shares issued in exchange of notes payable and accrued interest
Shares Issued In Exchange of Notes Payable and Accrued Interest
Shares issued in exchange of notes payable and accrued interest.
Non-controlling interest
Non-Controlling Interest [Policy Text Block]
Disclosure of accounting policy for non-controlling interest.
Noncontrolling interest
Deferred revenue
Increase (Decrease) in Contract with Customer, Liability
Deferred revenue
Income Statement Location [Domain]
Stock dividends issued for convertible preferred stock
Stock dividends issued for convertible preferred stock.
Stock dividends issued as Series O Convertible Preferred Stock
Stock dividends issued as Series O Convertible Preferred Stock
Furniture and fixtures
Furniture and fixtures
Number of shares issued for convertible preferred stock
Convertible Preferred Stock, Shares Issued upon Conversion
Participants Voting Power More than Ten Percent
Represents the information pertaining to participants voting power has more than ten percent.
Dividend payment rate variable
Preferred Stock, Dividend Payment Rate, Variable
Common stock issued to other third party for services (in shares)
Stock Issued During Period, Shares, Issued for Services
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]
Schedule of concentration risk
Number of highly characterized medicinal plants
Number of Highly Characterized Medicinal Plants
Number of highly characterized medicinal plants.
Payments to Alivus
Payments Made to Date to Alivus
Payments made to date to alivus.
Entity Tax Identification Number
Land
Land
Share Price
Share Price
Closing price
Notes payable
Short-term Debt [Abstract]
Options issued and outstanding
Stock Options Other Than Inducement Options [Member]
Represents information pertaining to stock options other than inducement stock options.
Debt term
Debt Instrument, Term
Royalty interest
Future Royalty Receivable
The amount of future royalty owed, treated as debt.
Organization and Business
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Vehicle lease agreement
ALD Automative Italia S r l [Member]
Represents information pertaining to ALD Automative Italia S.r.l agreement.
RSUs cancelled
Share Based Compensation Arrangement, By Share Based Payment Award, Restricted Stock Units, Available For Grant, Cancelled
The number of shares under RSU available for grant that were cancelled during the reporting period.
Non-controlling interests:
Noncontrolling interests:
Local Phone Number
Related Party Transaction [Domain]
Royalty instrument, Debt instrument carrying value
Royalty Instrument, Debt Instrument Carrying Value
The carrying value of royalty interest debt instrument.
Option shares outstanding
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Number of Outstanding Options
Commitments and Contingencies
Commitments and Contingencies [Line Items]
Commitments And Contingencies Line Items
Initial Collateral Requirement Subject to Reduction on Repayment of Unsecured Outstanding Obligations to Lender
Initial collateral requirement subject to reduction on repayment of unsecured outstanding obligations to lender.
Initial collateral requirement subject to reduction on repayment of unsecured outstanding obligations to lender
Office lease agreement
Office lease agreement
Represents information pertaining to an agreement for a lease of office premises.
Trademarks
Trademarks
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Stock issuance costs, issuance costs attributable to warrants
Uptown
Uptown [Member]
Uptown.
Goodwill impairment charges
Goodwill and Intangible Asset Impairment [Abstract]
Summary of Significant Accounting Policies
Disaggregation of Revenue [Line Items]
Uptown warrants
Uptown Warrants [Member]
Represents the information pertaining to Uptown Warrants.
Increase in royalty repayment amount
Increase In Royalty Repayment Amount
The amount of increase in royalty repayment amount.
License granted
Product revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Notes Designated at Fair Value Option
Notes designated at fair value option.
Notes designated at Fair Value Option
Lessee, Operating Lease, Liability, to be Paid, Year Four
2030
H C Wainwright and Co LLC [Member]
H.C. Wainwright & Co., LLC.
HC Wainwright And Co LLC
H C Wainwright and Co LLC
Reduced paid service for achievement of certain milestones
Reduced Paid Services Subject to Achievement of Certain Milestones
Amount of later reduced the paid on achievement of milestones.
Class of Stock [Domain]
Options available for grant under stock option plans
Beginning balance (in shares)
Ending balance (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Accrued audit and tax services
Accrued Professional Fees, Current
Human Health
Represents the information pertaining to human health segment.
Series J
Series J Convertible Preferred Stock [Member]
Represents the information pertaining to Series J convertible preferred stock.
Affiliated Entity
Affiliated Entity
Schedule of Stock by Class [Table]
Lab equipment
Lab equipment
Represents Lab equipment.
Entity Emerging Growth Company
Options vested and expected to vest (in years)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Indefinite-lived Intangible Assets [Axis]
Area (in square feet)
Area of Land
Percentage of Embedded Derivative Blended Exposure
Percentage of embedded derivative blended exposure.
Percentage of embedded derivative blended exposure