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TRAWS PHARMA, INC.
true
<div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;"> <span style="letter-spacing:0.2pt;">We do not have a written policy in place regarding the timing of the grant and issuance of stock options in relation to the release of material non-public information. Historically, we have typically granted option awards in the first quarter of the year, to the extent that options are awarded as a component of annual bonuses, shortly after the completion of our annual meeting of shareholders, and as may otherwise be deemed appropriate by our Board or Compensation Committee from time to time based on the facts and circumstances, as applicable. We have not intentionally timed the grant of stock options in anticipation of the release of material nonpublic information, nor have we intentionally timed the release of material nonpublic information based on stock option grant dates. </span> </div>
<div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;"> <span style="letter-spacing:0.2pt;">We do not have a written policy in place regarding the timing of the grant and issuance of stock options in relation to the release of material non-public information. Historically, we have typically granted option awards in the first quarter of the year, to the extent that options are awarded as a component of annual bonuses, shortly after the completion of our annual meeting of shareholders, and as may otherwise be deemed appropriate by our Board or Compensation Committee from time to time based on the facts and circumstances, as applicable. We have not intentionally timed the grant of stock options in anticipation of the release of material nonpublic information, nor have we intentionally timed the release of material nonpublic information based on stock option grant dates. </span> </div><div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;">
<span style="letter-spacing:0.2pt;">The date on which an equity award is granted is the date specified in the resolutions of the Board or Compensation Committee, as applicable, authorizing the grant. The grant date must fall on or after the date on which the resolutions are adopted by the Board or Compensation Committee. For stock options, the exercise price is the closing sale price of the Company’s common stock on the grant date, as reported by the Nasdaq Capital Market, or as otherwise required or permitted by the applicable equity plan under which the option is granted. Under our equity plans, the per share exercise price of an option cannot be less than the fair market value of a share of our common stock on the date of grant. </span>
</div><div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;">
<span style="letter-spacing:0.2pt;">During fiscal year 2025, we did not grant stock options (or similar awards) to any of our named executive officers during the period beginning four business days before and ending one business day after the filing of any Company periodic report on Form 10-Q or Form 10-K, or the filing or furnishing of any Company Form 8-K that disclosed any material non-public information.</span>
</div>
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We have not intentionally timed the grant of stock options in anticipation of the release of material nonpublic information, nor have we intentionally timed the release of material nonpublic information based on stock option grant dates.
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<table style="width:456pt;height:101.48pt;margin-top:10pt;border-collapse: collapse;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <tr style="line-height:8.44pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:7.5pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt; width:114.43pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.15pt;">Fiscal Year</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">SCT Total <br/> for PEO 1 <br/> ($)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">SCT Total <br/> for PEO 2 <br/> ($)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">Average SCT <br/> Total <br/> Compensation <br/> for Non-PEO <br/> NEOs <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">CAP to <br/> PEO 1 <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">CAP to <br/> PEO 2 <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">Average <br/> CAP to <br/> Non-PEO <br/> NEOs <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">Value of <br/> Initial Fixed <br/> $100 <br/> Investment <br/> Based on <br/> TSR <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:2.5pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.562pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.15pt;">GAAP Net <br/> Income <br/> (Loss) <br/> ($)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;"></td> </tr> <tr style="line-height:8.96999999999997pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:9pt;"> <td style="padding:3.27pt 0pt 1.79pt 0pt; width:114.43pt;text-align:left;"> <span style="letter-spacing:0.18pt;">2025</span><span style=" position:relative; bottom:3.75pt;font-size:5.5pt;letter-spacing:0.14pt;">(1)</span> </td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">353,897 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">1,401,924 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">874,425 </td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">218,333 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">985,755 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">669,789 </td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:19.5pt; text-align:right; white-space:nowrap;">1.77 </td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.27pt 0pt 1.79pt 0pt; min-width:39pt; text-align:right; white-space:nowrap;">9,170,000 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:8.96999999999997pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:9pt;"> <td style="padding:3.52pt 0pt 1.79pt 0pt; width:114.43pt;text-align:left;"> <span style="letter-spacing:0.18pt;">2024</span><span style=" position:relative; bottom:3.75pt;font-size:5.5pt;letter-spacing:0.14pt;">(2)</span> </td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">410,000 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">647,582 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">520,592 </td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">233,040 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">518,622 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">470,327 </td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:19.5pt; text-align:right; white-space:nowrap;">13.93 </td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.52pt 0pt 1.79pt 0pt; min-width:39pt; text-align:right; white-space:nowrap;">(166,523,000<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:8.96999999999997pt;background-color:#CCEEFF;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:9pt;"> <td style="padding:3.53pt 0pt 1.79pt 0pt; width:114.43pt;text-align:left;"> <span style="letter-spacing:0.18pt;">2023</span><span style=" position:relative; bottom:3.75pt;font-size:5.5pt;letter-spacing:0.14pt;">(3)</span> </td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">1,106,747 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-1">—</span> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">574,694 </td> <td style="padding:0pt;padding-left:7.465pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:32.25pt; text-align:right; white-space:nowrap;">1,296,543 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;"><span style="-sec-ix-hidden: hidden-fact-2">—</span> </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">623,539 </td> <td style="padding:0pt;padding-left:1.255pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:19.5pt; text-align:right; white-space:nowrap;">10.67 </td> <td style="padding:0pt;padding-left:8.94pt;width:0pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt; width:2.5pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.53pt 0pt 1.79pt 0pt; min-width:39pt; text-align:right; white-space:nowrap;">(18,948,000<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> </table>
<div style="margin-top:12.81pt; width:456pt;">
<div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; "></div>
</div>
<div style=" float:left; margin-top:8pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(1)</span> <br/> </div>
<div style=" margin-top:8pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;"> <span style="letter-spacing:0.2pt;">The PEO 1 for 2025 is Werner Cautreels, Ph.D., who served as Chief Executive Officer of the Company until March 31, 2025. The PEO 2 for 2025 is Iain Dukes, D. Phil., who served as Interim Chief Executive Officer from March 31, 2025 to October 1, 2025 and as Chief Executive Officer since October 1, 2025. Non-PEO NEOs for 2025 are Charles Pauza and Nikolay Savchuk, Ph.D. </span> </div>
<div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div>
<div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(2)</span> <br/> </div>
<div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;">
<span style="letter-spacing:0.2pt;">The PEO 1 for 2024 is Steven M. Fruchtman, M.D., who served as Chief Executive Officer of the Company until April 1, 2024. The PEO 2 for 2024 is Werner Cautreels, Ph.D., who served as Chief Executive Officer of the Company from April 1, 2024 through the year ended December 31, 2024. Non-PEO NEOs for 2024 are Mark P. Guerin and Victor Moyo. </span>
</div>
<div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div>
<div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(3)</span> <br/> </div>
<div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;">
<span style="letter-spacing:0.2pt;">The PEO 1 for 2023 is Steven M. Fruchtman, M.D.; there was no PEO 2 for 2023. Non-PEO NEOs for 2023 are Mark P. Guerin and Victor Moyo. </span>
</div>
<div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div>
<div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;font-size:10pt;">
<span style="letter-spacing:0.2pt;">The following table provides additional information on how the preliminary 2025 CAP amounts were determined, starting with SCT compensation and applying the required adjustments, as applicable, in accordance with the PVP rules. Prior-year PVP amounts are carried forward from the Company’s previously disclosed pay versus performance table. </span>
</div><table style="width:456pt;height:125.5pt;margin-top:0pt;border-collapse: collapse;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:40pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Fiscal Year</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:138.51pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Covered Executive(s)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">SCT Total <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Less: <br/> Grant-Date <br/> Fair Value <br/> of Stock <br/> and Option <br/> Awards <br/> Reported <br/> in SCT <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add: Year-End /</span><br/><span style="letter-spacing:-0.16pt;">Vest-Date Fair<br/>Value of Equity<br/>Awards Included<br/>for CAP <br/>($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span></div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add/(Deduct): <br/> Change in Fair Value <br/> of Prior-Year Awards <br/> Included for CAP <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(2)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">CAP <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:138.51pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">PEO 1 – Werner Cautreels,Ph.D. </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">353,897</td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(130,157<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">54,253</td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(59,660<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">218,333 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">PEO 2 – Iain Dukes, D. Phil.</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">1,401,924 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(625,549<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">229,515 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(20,135<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">985,755 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">Average Non-PEO NEOs</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">874,425 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(285,772<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">105,745 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(24,610<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">669,789</td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> </table>
<div style="margin-top:12.5pt; width:456pt;">
<div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; "></div>
</div>
<div style=" float:left; margin-top:8pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(1)</span>
<br/>
</div>
<div style=" margin-top:8pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the fair value as of the indicated fiscal year-end, or the vesting date if earlier, of applicable equity awards, calculated using the methodology used for financial reporting purposes. </span>
</div>
<div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div>
<div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(2)</span>
<br/>
</div>
<div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the change in fair value during the indicated fiscal year of applicable equity awards granted in a prior fiscal year and that remained outstanding and unvested as of the last day of the indicated fiscal year or vested during the indicated fiscal year, calculated in accordance with the methodology used for financial reporting purposes. </span>
</div>
<div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div>
353897
1401924
874425
218333
985755
669789
1.77
9170000
410000
647582
520592
233040
518622
470327
13.93
-166523000
1106747
574694
1296543
623539
10.67
-18948000
<div style=" float:left; margin-top:8pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(1)</span> <br/> </div><div style=" margin-top:8pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;"> <span style="letter-spacing:0.2pt;">The PEO 1 for 2025 is Werner Cautreels, Ph.D., who served as Chief Executive Officer of the Company until March 31, 2025. The PEO 2 for 2025 is Iain Dukes, D. Phil., who served as Interim Chief Executive Officer from March 31, 2025 to October 1, 2025 and as Chief Executive Officer since October 1, 2025. Non-PEO NEOs for 2025 are Charles Pauza and Nikolay Savchuk, Ph.D. </span> </div>
Werner Cautreels
Iain Dukes
<div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(2)</span> <br/> </div><div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;">
<span style="letter-spacing:0.2pt;">The PEO 1 for 2024 is Steven M. Fruchtman, M.D., who served as Chief Executive Officer of the Company until April 1, 2024. The PEO 2 for 2024 is Werner Cautreels, Ph.D., who served as Chief Executive Officer of the Company from April 1, 2024 through the year ended December 31, 2024. Non-PEO NEOs for 2024 are Mark P. Guerin and Victor Moyo. </span>
</div>
<div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;font-size:10pt;"> <span style="letter-spacing:0.2pt;">(3)</span> <br/> </div><div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;font-size:10pt;">
<span style="letter-spacing:0.2pt;">The PEO 1 for 2023 is Steven M. Fruchtman, M.D.; there was no PEO 2 for 2023. Non-PEO NEOs for 2023 are Mark P. Guerin and Victor Moyo. </span>
</div>
<table style="width:456pt;height:125.5pt;margin-top:0pt;border-collapse: collapse;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:40pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Fiscal Year</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:138.51pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Covered Executive(s)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">SCT Total <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Less: <br/> Grant-Date <br/> Fair Value <br/> of Stock <br/> and Option <br/> Awards <br/> Reported <br/> in SCT <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add: Year-End /</span><br/><span style="letter-spacing:-0.16pt;">Vest-Date Fair<br/>Value of Equity<br/>Awards Included<br/>for CAP <br/>($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span></div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add/(Deduct): <br/> Change in Fair Value <br/> of Prior-Year Awards <br/> Included for CAP <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(2)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">CAP <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:138.51pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">PEO 1 – Werner Cautreels,Ph.D. </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">353,897</td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(130,157<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">54,253</td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(59,660<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">218,333 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">PEO 2 – Iain Dukes, D. Phil.</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">1,401,924 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(625,549<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">229,515 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(20,135<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">985,755 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">Average Non-PEO NEOs</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">874,425 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(285,772<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">105,745 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(24,610<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">669,789</td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; "></div><div style=" float:left; margin-top:8pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(1)</span>
<br/>
</div><div style=" margin-top:8pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the fair value as of the indicated fiscal year-end, or the vesting date if earlier, of applicable equity awards, calculated using the methodology used for financial reporting purposes. </span>
</div><div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div><div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(2)</span>
<br/>
</div><div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the change in fair value during the indicated fiscal year of applicable equity awards granted in a prior fiscal year and that remained outstanding and unvested as of the last day of the indicated fiscal year or vested during the indicated fiscal year, calculated in accordance with the methodology used for financial reporting purposes. </span>
</div>
<table style="width:456pt;height:125.5pt;margin-top:0pt;border-collapse: collapse;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <tr style="line-height:9pt;white-space:nowrap;text-align:center;vertical-align:bottom;font-style:normal;font-weight:bold;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:8pt;"> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:40pt;text-align:left;"> <div style="white-space:nowrap;"> <span style="letter-spacing:-0.16pt;">Fiscal Year</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt; width:138.51pt;"> <div style="white-space:nowrap; text-align:center;"> <span style="letter-spacing:-0.16pt;">Covered Executive(s)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">SCT Total <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Less: <br/> Grant-Date <br/> Fair Value <br/> of Stock <br/> and Option <br/> Awards <br/> Reported <br/> in SCT <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add: Year-End /</span><br/><span style="letter-spacing:-0.16pt;">Vest-Date Fair<br/>Value of Equity<br/>Awards Included<br/>for CAP <br/>($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(1)</span></div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">Add/(Deduct): <br/> Change in Fair Value <br/> of Prior-Year Awards <br/> Included for CAP <br/> ($)</span><span style=" position:relative; bottom:3.25pt;line-height:5pt;font-size:5pt;letter-spacing:-0.12pt;">(2)</span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:3.31pt;"></td> <td colspan="4" style="border-bottom:1px solid #000000;padding:0pt 0pt 2.167pt 0pt;"> <div style="text-align:center;"> <span style="letter-spacing:-0.16pt;">CAP <br/> ($) </span> </div> </td> <td style="padding:0pt;border-bottom:1px solid #FFFFFF; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; width:138.51pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">PEO 1 – Werner Cautreels,Ph.D. </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">353,897</td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(130,157<span style="position:absolute;">)</span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">54,253</td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(59,660<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.25pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">218,333 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">PEO 2 – Iain Dukes, D. Phil.</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">1,401,924 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(625,549<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">229,515 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(20,135<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">985,755 </td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> <tr style="line-height:10pt;background-color:#CCEEFF;white-space:nowrap;text-align:left;vertical-align:bottom;font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;color:#000000;font-family:Times New Roman, Times, serif ;font-size:10pt;"> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:40pt;"> <div style="white-space:nowrap;"> <span style="letter-spacing:0.2pt;">2025 </span> </div> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; width:138.51pt;"> <span style="letter-spacing:0.2pt;">Average Non-PEO NEOs</span> </td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:33.75pt; text-align:right; white-space:nowrap;">874,425 </td> <td style="padding:0pt;padding-left:0.00500000000000256pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27pt; text-align:right; white-space:nowrap;">(285,772<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:1.35pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">105,745 </td> <td style="padding:0pt;padding-left:10.94pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:23.25pt; text-align:right; white-space:nowrap;">(24,610<span style="position:absolute;">) </span></td> <td style="padding:0pt;padding-left:20.14pt;width:0pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt; width:3.31pt;"></td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:0pt; text-align:right; "></td> <td style="padding:3.5pt 0pt 1.5pt 0pt; min-width:27.75pt; text-align:right; white-space:nowrap;">669,789</td> <td style="padding:0pt;padding-left:0pt;width:0pt;"></td> <td style="padding:0pt; width:0pt;"></td> </tr> </table><div style="margin-left: 0pt; width: 108pt; margin-top: 0pt; font-size: 1pt; line-height: 0pt; border-bottom: 1pt solid #000000; "></div><div style=" float:left; margin-top:8pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(1)</span>
<br/>
</div><div style=" margin-top:8pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the fair value as of the indicated fiscal year-end, or the vesting date if earlier, of applicable equity awards, calculated using the methodology used for financial reporting purposes. </span>
</div><div style="clear:both; padding:0pt; margin:0pt;font-size:0pt;line-height:0pt;"></div><div style=" float:left; line-height:12pt; margin-top:4pt; margin-bottom:0pt; text-align:left; width:20pt;white-space:nowrap;">
<span style="letter-spacing:0.2pt;">(2)</span>
<br/>
</div><div style=" margin-top:4pt; margin-bottom:0pt; line-height:12pt; text-align:left; margin-left:20pt;">
<span style="letter-spacing:0.2pt;">These amounts represent the change in fair value during the indicated fiscal year of applicable equity awards granted in a prior fiscal year and that remained outstanding and unvested as of the last day of the indicated fiscal year or vested during the indicated fiscal year, calculated in accordance with the methodology used for financial reporting purposes. </span>
</div>
353897
-130157
54253
-59660
218333
1401924
-625549
229515
-20135
985755
874425
-285772
105745
-24610
669789
<div style="margin-top:12pt; width:456pt; line-height:12pt;font-style:italic;">
<span style=" text-decoration:underline #000000 solid;letter-spacing:0.2pt;">Relationship between CAP and TSR</span><span style="font-style:normal;letter-spacing:0.2pt;"> </span>
</div>
<div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;">
<span style="letter-spacing:0.2pt;">During fiscal 2023, 2024 and 2025, the value of an initial fixed $100 investment based on total shareholder return was $10.67, $13.93 and $1.77, respectively. CAP amounts for the PEOs and average CAP for the non-PEO NEOs did not move in lockstep with TSR over this period. The differences reflect, among other things, the impact of changes in the fair value of equity awards used in calculating CAP and the Company’s CEO transitions during 2024 and 2025. </span>
</div>
<div style="margin-top:12pt; width:456pt; line-height:12pt;font-style:italic;">
<span style=" text-decoration:underline #000000 solid;letter-spacing:0.2pt;">Relationship between CAP and Net Income (Loss)</span><span style="font-style:normal;letter-spacing:0.2pt;"> </span>
</div>
<div style="text-indent:20pt; margin-top:8pt; width:456pt; line-height:12pt;">
<span style="letter-spacing:0.2pt;">During fiscal 2023, 2024 and 2025, the Company reported GAAP net income (loss) of $(18.9) million, $(166.5) million and $9.2 million, respectively. CAP did not correlate directly with GAAP net income (loss) during the period, as CAP is significantly affected by equity award valuation changes and executive transitions, while GAAP net income (loss) is affected by broader operating results and non-cash accounting items. </span>
</div>
PRE 14A
0001130598
false