0001479615 dei:AdrMember 2026-05-18 2026-05-18 0001479615 2026-05-18 2026-05-18 0001479615 us-gaap:CommonStockMember 2026-05-18 2026-05-18 true 0001479615 false 00-0000000 8-K 2026-05-18 Silence Therapeutics plc X0 001-39487 12 Hammersmith Grove London GB W6 7AP 44 20 3457 6900 false false false false American Depositary Shares, each representing three ordinary shares, nominal value £0.05 per share SLN NASDAQ Ordinary share, nominal value £0.05 per share NASDAQ false