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  <xsd:element name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityAdditionsFromDebtExtinguishment" id="nwbo_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityAdditionsFromDebtExtinguishment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ScheduleOfStockholdersEquityNoteWarrantModificationsTableTextBlock" id="nwbo_ScheduleOfStockholdersEquityNoteWarrantModificationsTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ChangeInFairValueOfConvertibleDebt" id="nwbo_ChangeInFairValueOfConvertibleDebt" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CommonStockWarrantsEquityClassifiedMember" id="nwbo_CommonStockWarrantsEquityClassifiedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CommonStockWarrantsLiabilityClassifiedMember" id="nwbo_CommonStockWarrantsLiabilityClassifiedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityDebtConversion" id="nwbo_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityDebtConversion" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="StockIssuedDuringPeriodSharesCashlessWarrantsExercise" id="nwbo_StockIssuedDuringPeriodSharesCashlessWarrantsExercise" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SharePayableMember" id="nwbo_SharePayableMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LesseeOperatingLeaseQuarterlyTerminationCost" id="nwbo_LesseeOperatingLeaseQuarterlyTerminationCost" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LesseeOperatingLeaseMaximumTermOfLeaseTerminationContract" id="nwbo_LesseeOperatingLeaseMaximumTermOfLeaseTerminationContract" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="BusinessCombinationConsiderationPaymentDueTerm" id="nwbo_BusinessCombinationConsiderationPaymentDueTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TwoYearConvertibleNotesMember" id="nwbo_TwoYearConvertibleNotesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ConvertibleNotesPayableNetNoncurrent" id="nwbo_ConvertibleNotesPayableNetNoncurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentConvertibleSpecifiedNumberOfRollingTradingDays" id="nwbo_DebtInstrumentConvertibleSpecifiedNumberOfRollingTradingDays" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentConvertibleThresholdNumberOfConsecutiveTradingDaysAfterNoticeOfConversion" id="nwbo_DebtInstrumentConvertibleThresholdNumberOfConsecutiveTradingDaysAfterNoticeOfConversion" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtInstrumentConvertibleLimitOnConversionPercentage" id="nwbo_DebtInstrumentConvertibleLimitOnConversionPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsByMajorClassTableTextBlock" id="nwbo_ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsByMajorClassTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="BusinessCombinationAccountsPayableAmountExcludedFromTransaction" id="nwbo_BusinessCombinationAccountsPayableAmountExcludedFromTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="BusinessCombinationUnpaidAccountsPayableStatedInterestRate" id="nwbo_BusinessCombinationUnpaidAccountsPayableStatedInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="LossContingencyAccrualAdditionalLiabilityRecognized" id="nwbo_LossContingencyAccrualAdditionalLiabilityRecognized" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="TemporaryEquityStockConversionDuringPeriodShares" id="nwbo_TemporaryEquityStockConversionDuringPeriodShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TemporaryEquityStockConversionDuringPeriodValue" id="nwbo_TemporaryEquityStockConversionDuringPeriodValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="BusinessCombinationConsiderationTransferredLiabilitiesAssumed" id="nwbo_BusinessCombinationConsiderationTransferredLiabilitiesAssumed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour" id="nwbo_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="BusinessCombinationAccruedInterestExpense" id="nwbo_BusinessCombinationAccruedInterestExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LongTermConvertibleNotesAtFairValueNinePercentUnsecuredMember" id="nwbo_LongTermConvertibleNotesAtFairValueNinePercentUnsecuredMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdditionalConvertibleNoteMember" id="nwbo_AdditionalConvertibleNoteMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DebtInstrumentContractualTerm" id="nwbo_DebtInstrumentContractualTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConvertibleNotesAtFairValueMember" id="nwbo_ConvertibleNotesAtFairValueMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfInstallmentsForRepaymentsOfLoans" id="nwbo_NumberOfInstallmentsForRepaymentsOfLoans" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="OriginalInterestRate" id="nwbo_OriginalInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="DebtInstrumentRepaymentPercentage" id="nwbo_DebtInstrumentRepaymentPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
</xsd:schema>
