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  <xsd:element id="fenc_ExpiryDateDomain" name="ExpiryDateDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityFinancingAxis" name="EquityFinancingAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityFinancingDomain" name="EquityFinancingDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ProcessaPharmaceuticalsIncMember" name="ProcessaPharmaceuticalsIncMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_LicenseAgreementMember" name="LicenseAgreementMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_CollaborativeArrangementSharesToBeIssued" name="CollaborativeArrangementSharesToBeIssued" nillable="true" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="fenc_MilestoneEventAxis" name="MilestoneEventAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ShareRestrictionExpirationTrancheAxis" name="ShareRestrictionExpirationTrancheAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_ShareRestrictionExpirationTrancheDomain" name="ShareRestrictionExpirationTrancheDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_MilestoneEventDomain" name="MilestoneEventDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="fenc_EquityIncentivePlanMember" name="EquityIncentivePlanMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element name="PedmarkMember" id="fenc_PedmarkMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DiscountsForPromptPayment" id="fenc_DiscountsForPromptPayment" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfPromptPaymentDiscountsExpectedToPayOut" id="fenc_PercentageOfPromptPaymentDiscountsExpectedToPayOut" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="GrossProductRevenue" id="fenc_GrossProductRevenue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ContributionOfRevenuePercentageDenotingSignificantCustomers" id="fenc_ContributionOfRevenuePercentageDenotingSignificantCustomers" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ChargebacksDiscountsForPromptPayAndOtherAllowancesMember" id="fenc_ChargebacksDiscountsForPromptPayAndOtherAllowancesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RebatesCustomerFeesCreditsAndCoPayAssistanceMember" id="fenc_RebatesCustomerFeesCreditsAndCoPayAssistanceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DiscountsAndAllowancesProvisionForCurrentPeriodSales" id="fenc_DiscountsAndAllowancesProvisionForCurrentPeriodSales" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DiscountsAndAllowancesPaymentsAndCustomerCreditsIssued" id="fenc_DiscountsAndAllowancesPaymentsAndCustomerCreditsIssued" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventory" id="fenc_ManufacturingCostsCapitalizedToInventory" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryWorkInProcess" id="fenc_ManufacturingCostsCapitalizedToInventoryWorkInProcess" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryFinishedGoods" id="fenc_ManufacturingCostsCapitalizedToInventoryFinishedGoods" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ManufacturingCostsCapitalizedToInventoryCostOfProductsSold" id="fenc_ManufacturingCostsCapitalizedToInventoryCostOfProductsSold" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CanadianFundsTranslatedIntoUsdMember" id="fenc_CanadianFundsTranslatedIntoUsdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LeaseContingenciesMember" id="fenc_LeaseContingenciesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExecutiveSeveranceMember" id="fenc_ExecutiveSeveranceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfSeverancePayments" id="fenc_NumberOfSeverancePayments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="TriangleParkNorthCarolinaMember" id="fenc_TriangleParkNorthCarolinaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="HobokenNewJerseyMember" id="fenc_HobokenNewJerseyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OfficeServiceAgreementMember" id="fenc_OfficeServiceAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OperatingLeaseDaysNoticeRequiredToTerminateAgreement" id="fenc_OperatingLeaseDaysNoticeRequiredToTerminateAgreement" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="OperatingLeaseNumberOfScheduledPaymentIncreases" id="fenc_OperatingLeaseNumberOfScheduledPaymentIncreases" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="OperatingLeasePenaltiesAndContingentPaymentsPayable" id="fenc_OperatingLeasePenaltiesAndContingentPaymentsPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LitigationCiplaAndaMember" id="fenc_LitigationCiplaAndaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DaysFollowingReceiptOfNoticeLetterToFilePatentInfringementSuit" id="fenc_DaysFollowingReceiptOfNoticeLetterToFilePatentInfringementSuit" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DurationOfFdaSAbilityToGiveFinalApprovalToProposedProductsThatReferencePedmark" id="fenc_DurationOfFdaSAbilityToGiveFinalApprovalToProposedProductsThatReferencePedmark" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PedmarkSOrphanDrugExclusivityPeriod" id="fenc_PedmarkSOrphanDrugExclusivityPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProvisionForDiscountsAndAllowances" id="fenc_ProvisionForDiscountsAndAllowances" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProductSalesDiscountsAndAllowancesPolicyTextBlock" id="fenc_ProductSalesDiscountsAndAllowancesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="RefundsDiscountsAndAllowances" id="fenc_RefundsDiscountsAndAllowances" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LicenseAgreementFundingReceived" id="fenc_LicenseAgreementFundingReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LicenseAgreementFundingPotentialMilestonePayments" id="fenc_LicenseAgreementFundingPotentialMilestonePayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ExclusiveLicensingAgreementMember" id="fenc_ExclusiveLicensingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NorgineLtdMember" id="fenc_NorgineLtdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementPolicyPolicyTextBlock" id="fenc_LicenseAgreementPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="IncrementalCostsCapitalizedToOtherNonCurrentAssets" id="fenc_IncrementalCostsCapitalizedToOtherNonCurrentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="IncrementalCostsPaid" id="fenc_IncrementalCostsPaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CostOfProductSales" id="fenc_CostOfProductSales" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ScheduleOfPedmarkRevenuesDiscountsAndAllowancesTableTextBlock" id="fenc_ScheduleOfPedmarkRevenuesDiscountsAndAllowancesTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ScheduleOfPedmarkRevenuesNetTableTextBlock" id="fenc_ScheduleOfPedmarkRevenuesNetTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DilutiveEffectOfRestrictedShareUnits" id="fenc_DilutiveEffectOfRestrictedShareUnits" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TermOfExecutiveSeveranceInEventOfTermination" id="fenc_TermOfExecutiveSeveranceInEventOfTermination" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SecondOfficeServiceAgreementMember" id="fenc_SecondOfficeServiceAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RostislavRaykovBoardOfDirectorsMember" id="fenc_RostislavRaykovBoardOfDirectorsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsToPurchaseCommonSharesMember" id="fenc_WarrantsToPurchaseCommonSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RestrictedStockOptionsMember" id="fenc_RestrictedStockOptionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OptionsToPurchaseCommonSharesMember" id="fenc_OptionsToPurchaseCommonSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnrealizedLossOnAvailableForSaleSecurities" id="fenc_UnrealizedLossOnAvailableForSaleSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AllowanceForTradeCreditLossesPolicyTextBlock" id="fenc_AllowanceForTradeCreditLossesPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConvertibleNotesToCommonStockMember" id="fenc_ConvertibleNotesToCommonStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExecutiveSeveranceMonthsOfCurrentBaseSalaryPayable" id="fenc_ExecutiveSeveranceMonthsOfCurrentBaseSalaryPayable" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="EquityIncentivePlanAmendmentMember" id="fenc_EquityIncentivePlanAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ChrisRallisMember" id="fenc_ChrisRallisMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicensingAgreementTable" id="fenc_LicensingAgreementTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="LicenseAgreementLineItems" id="fenc_LicenseAgreementLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfCustomersWithConcentrationRisk" id="fenc_NumberOfCustomersWithConcentrationRisk" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ReclassificationsPolicyPolicyTextBlock" id="fenc_ReclassificationsPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
</xsd:schema>
