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  <xsd:element name="PreClinicalResearchPreclinicalOcularDiseases" id="mgtx_PreClinicalResearchPreclinicalOcularDiseases" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SegmentNetIncomeLoss" id="mgtx_SegmentNetIncomeLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SegmentGeneralAndAdministrativeExpenses" id="mgtx_SegmentGeneralAndAdministrativeExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestoneFundingUpfrontPaymentReceived" id="mgtx_MilestoneFundingUpfrontPaymentReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MilestoneFundingToProvideAdditionalCapital" id="mgtx_MilestoneFundingToProvideAdditionalCapital" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="HologenTransactionAgreementMember" id="mgtx_HologenTransactionAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="HologenLimitedMember" id="mgtx_HologenLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassSharesOfHologenReceivedInTransaction" id="mgtx_ClassSharesOfHologenReceivedInTransaction" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NonCashTransactionReceivableFromSaleOfFixedAssetsIncludedInOtherCurrentAssets" id="mgtx_NonCashTransactionReceivableFromSaleOfFixedAssetsIncludedInOtherCurrentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="GainOnTerminationOfLeaseLiabilities" id="mgtx_GainOnTerminationOfLeaseLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="Rule10b51ArrangementModifiedFlag" id="mgtx_Rule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NonRule10b51ArrangementModifiedFlag" id="mgtx_NonRule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="RelatedPartyServiceRevenueMember" id="mgtx_RelatedPartyServiceRevenueMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdditionalMilestonePaymentReceived" id="mgtx_AdditionalMilestonePaymentReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="EliLillyAndCompanyMember" id="mgtx_EliLillyAndCompanyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="EliLillyAndCompanyCollaborationAgreementMember" id="mgtx_EliLillyAndCompanyCollaborationAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MilestoneFundingAvailableUponCertainDevelopmentAndRegulatoryApprovals" id="mgtx_MilestoneFundingAvailableUponCertainDevelopmentAndRegulatoryApprovals" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ChangeInRightOfUseAssets" id="mgtx_ChangeInRightOfUseAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="UpfrontPaymentLiabilitiesCurrent" id="mgtx_UpfrontPaymentLiabilitiesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="StuartNaylorMember" id="mgtx_StuartNaylorMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareRepurchaseAgreementWithPerceptiveLifeSciencesMasterFundLtdMember" id="mgtx_ShareRepurchaseAgreementWithPerceptiveLifeSciencesMasterFundLtdMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DebtInstrumentPrincipalAmountAmountToRedeem" id="mgtx_DebtInstrumentPrincipalAmountAmountToRedeem" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="IncreaseDecreaseInLeaseLiabilities" id="mgtx_IncreaseDecreaseInLeaseLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ResearchDevelopmentAndOtherAssetsMember" id="mgtx_ResearchDevelopmentAndOtherAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PublicOfferingMember" id="mgtx_PublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="HologenNeuroAiLimitedMember" id="mgtx_HologenNeuroAiLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MeiragtxNeuroUkLimitedMember" id="mgtx_MeiragtxNeuroUkLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfLateStageClinicalPrograms" id="mgtx_NumberOfLateStageClinicalPrograms" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfGmpLicensedManufacturingFacilities" id="mgtx_NumberOfGmpLicensedManufacturingFacilities" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MinimumDevelopmentPeriodOfProprietaryManufacturingPlatform" id="mgtx_MinimumDevelopmentPeriodOfProprietaryManufacturingPlatform" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MinimumNumberOfDistinctViralVectorsUtilized" id="mgtx_MinimumNumberOfDistinctViralVectorsUtilized" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MaximumOwnershipPercentageMayHoldIfOptionIsExercised" id="mgtx_MaximumOwnershipPercentageMayHoldIfOptionIsExercised" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="MeiragtxManufacturingLimitedMember" id="mgtx_MeiragtxManufacturingLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AgreementOptionExercisePeriod" id="mgtx_AgreementOptionExercisePeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SalesThresholdRequiredToTriggerContingentConsiderationPayment" id="mgtx_SalesThresholdRequiredToTriggerContingentConsiderationPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MilestonePaymentToBeReceived" id="mgtx_MilestonePaymentToBeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="AgreementSellOrTransferOfSharesNoticePeriod" id="mgtx_AgreementSellOrTransferOfSharesNoticePeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
</xsd:schema>
