v3.26.1
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Cash flows from operating activities:    
Net loss $ (46,313) $ (39,981)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 3,654 4,887
Foreign currency loss (gain) 2,837 (3,687)
Depreciation and amortization 3,008 3,081
Change in right-of-use assets 653 4,299
Gain on termination of lease liabilities   (1,365)
Loss (gain) on disposal of equipment, furniture and fixtures 55 (122)
Amortization of interest on asset retirement obligations 36 63
Amortization of debt discount 228 274
Acquired in-process research and development 499  
(Increase) decrease in operating assets:    
Accounts receivable - related party (260) (49)
Contract assets - related party   701
Inventory   (203)
Prepaid expenses (42) 7
Tax incentive receivable   4,851
Other current assets (113) 1,638
Other assets, net 1,276  
Increase (decrease) in operating liabilities:    
Accounts payable 7,909 (3,061)
Accrued expenses (9,904) (3,585)
Lease liabilities (1,266) (4,228)
Other current liabilities 55,603 (19)
Deferred revenue - related party (50) (329)
Net cash provided by (used in) operating activities 17,810 (36,828)
Cash flows from investing activities:    
Purchase of property, plant and equipment (2,008) (1,710)
Acquisition of in-process research and development assets (250)  
Net cash used in investing activities (2,258) (1,710)
Cash flows from financing activities:    
Exercise of share options 62 4
Payments of withholdings on shares withheld for income taxes (5,960) (2,761)
Payments on lease obligations - financing leases (14)  
Proceeds from the issuance of ordinary shares 14,027 4,482
Issuance costs in connection with ordinary shares (35) (12)
Payment for treasury shares (18,193)  
Net cash (used in) provided by financing activities (10,113) 1,713
Net increase (decrease) in cash, cash equivalents and restricted cash 5,439 (36,825)
Effect of exchange rate changes on cash, cash equivalents and restricted cash 126 (233)
Cash, cash equivalents and restricted cash at beginning of the period 68,193 105,668
Cash, cash equivalents and restricted cash at end of the period 73,758 68,610
Supplemental disclosure of non-cash transactions:    
Fixed asset acquisitions included in accounts payable and accrued expenses 920 615
Change in estimate of asset retirement obligation   (1,576)
Issuance of shares in connection with acquisition of in-process research and development asset 249  
Receivable from sale of fixed assets included in other current assets 9 125
Supplemental disclosure of cash flow information:    
Cash paid for interest $ 2,710 $ 2,863