75000 - Document - Document and Entity Information
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75010 - Statement - Unaudited Consolidated Balance Sheets
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75020 - Statement - Unaudited Consolidated Balance Sheets (Parenthetical)
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75030 - Statement - Unaudited Consolidated Statements of Operations and Comprehensive Loss
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75040 - Statement - Unaudited Consolidated Statements of Stockholders' Equity (Unaudited)
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75050 - Statement - Unaudited Consolidated Statements of Cash Flows
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995455 - Disclosure - Nature of Business
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Revision of Previously Issued Financial Statements
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995485 - Disclosure - Fair Value of Financial Instruments
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995495 - Disclosure - Available-for-Sale Securities
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995505 - Disclosure - Property and Equipment, Net
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995515 - Disclosure - Assets Held for Sale
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995525 - Disclosure - Prepaid Expenses and Other Current Assets
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995535 - Disclosure - Accrued Expenses
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995545 - Disclosure - Restructuring and Other Charges
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995555 - Disclosure - Stockholders' Equity
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995565 - Disclosure - Equity based Compensation
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995575 - Disclosure - Collaboration Agreements
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995585 - Disclosure - Net Income per Share
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995595 - Disclosure - Share Repurchase
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995605 - Disclosure - Commitments and Contingencies
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995615 - Disclosure - Related-Party Transactions
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995625 - Disclosure - Income Taxes
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995635 - Disclosure - Subsequent Events
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995645 - Disclosure - Segment Information
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995655 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995665 - Disclosure - Revision of Previously Issued Financial Statements (Tables)
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995675 - Disclosure - Fair Value of Financial Instruments (Tables)
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995685 - Disclosure - Available-for-Sale Securities (Tables)
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995695 - Disclosure - Property and Equipment, Net (Tables)
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995705 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995715 - Disclosure - Accrued Expenses (Tables)
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995725 - Disclosure - Stockholders' Equity (Tables)
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995735 - Disclosure - Equity based Compensation (Tables)
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995745 - Disclosure - Net Income per Share (Tables)
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995755 - Disclosure - Segment Information (Tables)
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995765 - Disclosure - Nature of Business - Additional Information (Detail)
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995775 - Disclosure - Summary of Significant Accounting Policies (Additional Information) (Details)
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995785 - Disclosure - Revision of Previously Issued Financial Statements - Revised prior period amounts on the consolidated financial statements to correct the misstatement (Details)
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995795 - Disclosure - Fair Value of Financial Instruments - Schedule of Company's Classified Assets Measured at Fair Value on Recurring Basis (Detail)
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995805 - Disclosure - Fair Value of Financial Instruments - Schedule of Assets measured at fair value and the gross unrealized holding gains and losses (Details)
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995815 - Disclosure - Fair Value of Financial Instruments - Schedule of Assumptions Used in Determining Fair Value of Warrants (Details)
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995825 - Disclosure - Available-for-Sale Securities - Summary of Available-for-Sale Securities Held (Detail)
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995835 - Disclosure - Available-for-Sale Securities - Additional Information (Detail)
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995845 - Disclosure - Assets Held for Sale (Additional Information) (Details)
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995855 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail)
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995865 - Disclosure - Prepaid Expenses and Other Current Assets (Details)
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995875 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail)
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995885 - Disclosure - Restructuring and Other Charges (Additional Information) (Details)
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995895 - Disclosure - Stockholders Equity - Additional Information (Detail)
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995905 - Disclosure - Stockholders Equity - Schedule of Shares of Common Stock Reserved for Future Issuance (Detail)
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995915 - Disclosure - Equity-based Compensation - Additional Information (Detail)
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995925 - Disclosure - Equity-based Compensation - Schedule of Equity-based Compensation Expenses (Detail)
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995935 - Disclosure - Equity-based Compensation - Schedule of Equity-based Compensation Expenses by Award Type (Detail)
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995945 - Disclosure - Collaboration Agreements - Additional Information (Detail)
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995955 - Disclosure - Net Income per Share - Additional Information (Detail)
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995965 - Disclosure - Net Income per Share - Summary of Computation of Basic and Diluted Net Loss per Share (Details)
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995975 - Disclosure - Net Income per Share - Schedule of Potentially Common Shares Excluded from Calculation of Net Loss Per share (Details)
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995985 - Disclosure - Share Repurchase (Additional Information) (Details)
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995995 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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996005 - Disclosure - Related-Party Transactions - Additional Information (Detail)
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996015 - Disclosure - Income Taxes (Additional Information) (Details)
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996025 - Disclosure - Segment Information (Additional Information) (Details)
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996035 - Disclosure - Segment Information - Summary of Research and Development, General and Administrative Expenses, and Restructuring Charges are Significant Segment Expenses (Details)
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996045 - Disclosure - Subsequent Events (Additional Information) (Details)
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Proceeds from the sale of property and equipment
Proceeds from the sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment
Other Research and Development Expense
Other Research and Development Expense
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Balance Sheet Location
Statement of Financial Position Location, Balance [Domain]
Revision of Prior Period [Axis]
Plan Name
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Proceeds from Warrant Exercises
Proceeds from exercise of warrants
Proceeds from exercise of pre-funded warrants
Operating Expenses [Abstract]
Operating expenses:
Significant Other Observable Inputs (Level 2)
Fair Value, Inputs, Level 2 [Member]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, authorized
Common Stock, Shares Authorized
Document Fiscal Period Focus
Document Fiscal Period Focus
Entity Shell Company
Entity Shell Company
Other
Other Accrued Liabilities, Current
Supplemental disclosure of non-cash investing activities:
Noncash Investing Items [Abstract]
Noncash investing items.
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalent
Cash and cash equivalents
Operating Lease, Impairment Loss
Impairment loss on ROU assets
Impairment related to lease
Long Term Incentive Plan 2025 [Member]
Long Term Incentive Plan 2025 [Member]
Plan 2025
Common stock, Issued
Common Stock, Shares, Issued
Asset Class [Domain]
Statement [Table]
Statement [Table]
Restricted cash
Restricted Cash, Noncurrent
Statement [Line Items]
Statement [Line Items]
Warrant [Member]
Warrant
Warrants exercise price per share paid at closing of offering
Class Of Warrant Or Right Exercise Price Of Warrants Paid At Closing Of Offering
Class of warrant or right exercise price of warrants paid at closing of offering.
Entity Filer Category
Entity Filer Category
Total liabilities and stockholders' equity
Liabilities and Equity
Payables and Accruals [Abstract]
Gain Contingencies [Line Items]
Gain Contingencies [Line Items]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Severance Costs
Severance and related costs
Plan 2015
Long Term Incentive Plan2015 [Member]
Long Term Incentive Plan 2015.
Cash and Cash Equivalents, Fair Value Disclosure
Estimated Fair Value
Public offering price
Shares Issued, Price Per Share
Related party transaction collaboration agreement, initial term
Related party transaction collaboration agreement, initial term
Related Party Transaction Collaboration Agreement Initial Term
Related party transaction collaboration agreement, initial term.
Subsequent Event [Line Items]
Stock Option [Member]
Income Tax Jurisdiction [Axis]
Facility and All Other Costs [Member]
Facility and All Other Costs [Member]
Facility and all other costs
ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentsTextBlock
Schedule of Error Corrections and Prior Period Adjustments [Table Text Block]
Pre-Funded Warrants To Purchase
Pre-funded warrants to purchase
Pre-funded warrants to purchase
Schedule of Shares of Common Stock Reserved for Future Issuance
Schedule Of Shares Of Common Stock Reserved For Future Issuance Table [Text Block]
Schedule of shares of common stock reserved for future issuance.
Research and development
Accrued Research And Development Current
Accrued research and development, current.
Additional paid-in capital
Additional Paid in Capital, Common Stock
Additional paid-in capital
Two Thousand Seventeen And Two Thousand Twenty Five Equity Incentive Award Plan [Member]
Two Thousand Seventeen And Two Thousand Twenty Five Equity Incentive Award Plan [Member]
2017 Plan and 2025 Plan
U.S. treasuries
U S Government Agencies Debt Securities And Treasuries [Member]
US government agencies debt securities and treasuries.
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property Plant And Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Aggregate Purchase Per Share
Aggregate Purchase Per Share
Aggregate Purchase Per Share
Number of stock options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Schedule of Computation of Basic and Diluted Net Loss per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Share-Based Payment Arrangement [Member]
Potential shares issuable under the ESPP
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net income (loss per share) - basic
Basic EPS
2017 Plan and 2015 Plan
Two Thousand Seventeen And Two Thousand Fifteen Equity Incentive Award Plan [Member]
Two thousand seventeen and two thousand fifteen equity incentive award plan.
Summary of Available-for-Sale Securities Held
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Total current liabilities
Liabilities, Current
Options Exercisable to Purchase Common Stock
Options Exercisable To Purchase Common Stock [Member]
Options exercisable to purchase common stock.
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net income to net cash used in operating activities:
Pledging Purpose [Axis]
Effective Income Tax Rate Reconciliation [Table]
Existing lease obligations
Existing lease obligations
Existing Lease Obligations
Stockholders' equity
Equity, Attributable to Parent [Abstract]
Entity Small Business
Entity Small Business
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Prior Period Adjustment [Abstract]
Research and Development
Research and Development
Research and development
Preferred Stock [Member]
Sale of stock, price per share
Sale of Stock, Price Per Share
Share-Based Payment Arrangement [Text Block]
Equity-based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Amendment Flag
Amendment Flag
Long-Lived Asset, Held-for-Sale, Type [Axis]
Compensation and Benefits [Member]
Compensation and Benefits [Member]
Compensation and benefits
Roche Collaboration and Option Agreement
Roche Collaboration And Option Agreement [Member]
Roche collaboration and option agreement.
Warrants to purchase shares of common stock
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Liabilities and Stockholders' Equity
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Common Stock
Common Stock $0.001 Par Value
Common Stock [Member]
Research and development
Total Research and Development Expense
Total Research and Development Expense
Research and development
Research and development
Related Party Transaction Collaboration Agreement Initial Term Extended
Related Party Transaction Collaboration Agreement Initial Term Extended
Related Party Transaction Collaboration Agreement Initial Term Extended
Weighted average exercise price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Amortized Cost Fair Value
Amortized Cost Fair Value
Amortized Cost
Schedule of Available-for-sale Securities [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
Pre-funded warrant public offering price
Pre-Warrant at a public offering price
Pre-Warrant at a public offering price
Balance Sheet Location
Statement of Financial Position Location, Balance [Axis]
Investment Type [Axis]
Investment Type
Right of use asset - operating lease
Operating Lease, Right-of-Use Asset
Debt Securities, Available-for-Sale, Unrealized Loss Position, Total
Aggregate fair value of securities in unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position
Purchases of marketable securities
Payments to Acquire Debt Securities, Available-for-Sale
Class of Warrant or Right
Class of Warrant or Right [Axis]
Document Type
Document Type
Cash paid for income taxes
Income Taxes Paid, Net
Income Taxes Paid, Net, Total
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Investments, Debt and Equity Securities [Abstract]
Available-for-Sale Securities
Available For Sale Securities Disclosure [Text Block]
Available for sale securities disclosure.
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net decrease in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Change in fair value of purchase warrant liability
Fair Value Adjustment of Warrants
Fair Value Adjustment of Warrants
Change in fair value of purchase warrant liability
Anti-dilutive potential common shares excluded from the EPS computation above
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Option Indexed to Issuer's Equity
Option Indexed to Issuer's Equity [Axis]
Strike price
Share Based Compensation Arrangement By Shares Based Payment Award Fair Value Assumptions Strike Price
Share Based Compensation Arrangement By Shares Based Payment Award Fair Value Assumptions Strike Price
Common stock, par value
Common Stock, Par or Stated Value Per Share
Public offering less exercise price
Public Offering Less Exercise Price
Public Offering Less Exercise Price
Amortized cost
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-Sale, Total
Fair Value
Debt Securities, Available-for-Sale
Gain on lease termination
Gain (Loss) on Termination of Lease
Gain on lease termination
Gain on lease termination
Exercise of options, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Other prepaid expenses
Other Prepaid Expense, Current
Other Prepaid Expense, Current
Total accrued expenses
Accrued expenses
Accrued Liabilities, Current
Issuance of restricted stock
Stock Issued During Period, Value, Restricted Stock Award, Gross
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid expenses and other current assets.
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Former Headquarter Member
Former Headquarter [Member]
Former Headquarter [Member]
Two Thousand Twenty Three Inducement Plan [Member]
Two Thousand Twenty Three Inducement Plan [Member]
Document Quarterly Report
Document Quarterly Report
Entity Address, State or Province
Entity Address, State or Province
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive income
Gross unrealized gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Total Shares of Common Stock Reserved for Future Issuance
Common Stock, Capital Shares Reserved for Future Issuance
Class of Warrant or Right
Class of Warrant or Right [Domain]
Schedule of Equity-based Compensation Expenses
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Exercise of options
Stock Issued During Period, Value, Stock Options Exercised
Accrued Expenses
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Collaboration Agreements
Collaborative Arrangement Disclosure [Text Block]
Proceeds from maturity of marketable securities
Proceeds from Sale and Maturity of Marketable Securities
Subsequent Event [Member]
Subsequent Event [Member]
Property, Plant and Equipment [Abstract]
Increase in number of shares available for issuance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Other assets
Other Assets, Noncurrent
Short-term marketable securities
Debt Securities, Available-for-Sale, Current
Antidilutive Securities [Axis]
Schedule of Fair Value Assets and Liabilities Measured Gross Unrealized Gains and Losses
Schedule of Fair Value Assets and Liabilities Measured Gross Unrealized Gains and Losses [TableText Block]
Schedule of Fair Value Assets and Liabilities Measured Gross Unrealized Gains and Losses [TableText Block]
Accumulated Other Comprehensive Income (Loss)
AOCI Attributable to Parent [Member]
Decrease In Right-Of-Use Asset And Operating Lease Liabilities
Decrease in right-of-use asset and operating lease liabilities
Decrease in right-of-use asset and operating lease liabilities due to lease termination
Balance (in Shares)
Balance (in Shares)
Treasury Stock, Common, Shares
Balance (in Shares)
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of prepaid expenses and other current assets.
Schedule of Prepaid Expenses and Other Current Assets
Cash and Cash Equivalents
Cash and Cash Equivalents [Domain]
Total termination payment
Total Termination Payment
Total Termination Payment
Minimum [Member]
Minimum
Weighted average grant date fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Purchase Warrant Liability
Purchase Warrant Liability
Purchase warrant liability
Prepaid research and development, net of current portion
Prepaid Research And Development Noncurrent
Prepaid research and development noncurrent.
Significant Unobservable Inputs (Level 3)
Fair Value, Inputs, Level 3 [Member]
Liabilities, Fair Value Disclosure [Abstract]
Segment Information
Segment Reporting [Abstract]
Schedule of Company's Classified Assets Measured at Fair Value on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Reduction in carrying amount of operating lease right of use asset
Reduction In Carrying Amount Of Operating Lease Right Of Use Asset
Reduction in carrying amount of operating lease right-of-use asset.
Current liabilities:
Liabilities, Current [Abstract]
Restructuring and Related Activities Disclosure [Text Block]
Restructuring and Other Charges
Related Party Transactions [Abstract]
Balance (in Shares)
Balance (in Shares)
Shares, Outstanding
Prepaid Expense, Noncurrent, Total
Non-current pre-paid research and development
Prepaid Expense, Noncurrent
October 2023 Financing [Member]
October 2023 Financing [Member]
October 2023 Financing
Commitments and Contingencies
Commitments and contingencies (Note 10)
General and Administrative Expense
General and Administrative Expense [Member]
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Reverse Stock Split , Description
Stockholders' Equity, Reverse Stock Split
Reverse Stock Split, Decsription
Computer and Office Equipment
Computer And Office Equipment [Member]
Computer and office equipment.
Finance lease obligations
Finance Lease, Liability, Current
Long-term liabilities:
Liabilities, Noncurrent [Abstract]
Text Block [Abstract]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net income
Proceeds from employee stock purchases and exercise of stock options
Proceeds From Employee Stock Purchases And Exercise Of Stock Options
Proceeds from employee stock purchases and exercise of stock options.
Weighted Average Number of Shares Outstanding, Basic
Basic weighted-average common shares outstanding
Weighted-average common shares - basic
Weighted Average Number of Shares Outstanding, Basic, Total
Current Pre-Paid Research and Development
Current Pre Paid Research And Development
Current Pre-Paid Research and Development.
Document Information [Line Items]
Common stock at an exercise price
Common Stock At An Exercise Price
Common Stock At An Exercise Price
Accrued restructuring charges
Accrued restructuring charges.
Accrued restructuring charges.
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Share Based Compensation Arrangement By ShareBased PaymentAward Fair Value Assumptions Stock Price
Share Based Compensation Arrangement By ShareBased PaymentAward Fair Value Assumptions Stock Price
Stock Price
Stock Issued During Period, Shares, Reverse Stock Splits
Reverse Split: fractional share adjustment
Subsequent Events
Subsequent Events [Text Block]
Related-Party Transactions
Related Party Transactions Disclosure [Text Block]
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Equity-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Net Income Per Share [Table]
Net Income Per Share [Table]
Total stockholders' equity
Balance
Balance
Equity, Attributable to Parent
Total stockholders' equity
Preferred Stock Par Value
Preferred Stock, Par or Stated Value Per Share
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Prepaid research and development expenses
Prepaid Research And Development Expenses
Prepaid research and development expenses.
Statement of Stockholders' Equity [Abstract]
Non Current Pre-Paid Research and Development
Non Current Pre Paid Research And Development
Non Current Pre-Paid Research and Development
Series A Preferred Stock [Member]
Series A Preferred Stock [Member]
Treasury Stock, Common [Member]
Treasury Stock
Restructuring Additional Gain
Restructuring Reserve, Foreign Currency Translation Gain (Loss)
Restructuring including legal and consulting fees
Leasehold Improvements
Leasehold Improvements [Member]
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Schedule of Equity-based Compensation Expenses by Award Type
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Reverse Stock Split Approval Date
Reverse Stock Split Approval Date
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Other Assets, Current
Other current assets
Lab Equipment [Member]
Lab Equipment [Member]
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price And Additional Disclosures [Abstract]
Share-based compensation arrangement by share-based payment award, options outstanding, weighted average exercise price, and additional disclosures.
Agreed to pay to renovate and upgrade cleanroom space
Agreed To Pay To Renovate And Upgrade Cleanroom Space
Agreed to pay to renovate and upgrade cleanroom space.
Plan Name
Plan Name [Domain]
Increase (Decrease) in Other Operating Assets, Total
Other assets
Increase (Decrease) in Other Operating Assets
Impairment for in-process research and development
Impairment for in-process research and development
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity
Entity [Domain]
CashEquivalentsAccumulatedGrossUnrealizedLoss
CashEquivalentsAccumulatedGrossUnrealizedLoss
Gross Unrealized Loss
Treasury Stock, Value
Treasury Stock, Value, Total
Treasury stock, at cost (279,792 shares at March 31, 2026 and at December 31, 2025)
Restructuring Plan [Axis]
Related Party
Related and Nonrelated Parties [Axis]
Non Rule 10b51 Arr Modified Flag
Non Rule 10b51 Arr Modified Flag
Entity Address, City or Town
Entity Address, City or Town
Security Exchange Name
Security Exchange Name
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property and equipment, gross
Property, Plant and Equipment, Gross
Share Repurchase [Abstract]
Share Repurchase [Abstract]
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income taxes
Loss before income taxes
Restructuring Charges Expense Acceleration [Member]
Restructuring Charges Expense Acceleration [Member]
Restructuring charges: expense acceleration
Pledging Purpose [Domain]
Antidilutive Securities, Name [Domain]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrants exercise price per share
Assets, Current
Total current assets
Equity-based compensation expense
Share-Based Payment Arrangement, Expense
Property and equipment sales included in other current assets
Noncash or Part Noncash Acquisition, Fixed Assets Acquired
Federal and State Deferred Tax [Member]
Federal and state deferred tax
Federal and State Deferred Tax [Member]
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Gain (Loss) on Disposition of Property Plant Equipment, Total
Gains on equipment sales
Gain (Loss) on Disposition of Property Plant Equipment
Statement of Financial Position [Abstract]
(Gain)/loss on disposal of property and equipment
Disposal Group, Not Discontinued Operation, Gain (Loss) on Disposal
Gain on disposal of property and equipment
Antidilutive Security, Excluded EPS Calculation [Table]
Class of Stock [Axis]
Number of investments in unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Financial Instruments
Financial Instruments [Domain]
Effect of dilutive securities
Dilutive Securities, Effect on Basic Earnings Per Share
Dilutive Securities, Effect on Basic Earnings Per Share, Total
Restricted Common Stock
Restricted Stock [Member]
Restricted Stock Awards [Member]
Number of investments in unrealized loss position, more than twelve months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Diluted weighted-average common shares outstanding
Entity File Number
Securities Act File Number
Unrealized gain (loss) on securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Net unrealized loss on marketable securities
Rule 10b51 Arr Modified Flag
Rule 10b51 Arr Modified Flag
Cover [Abstract]
Restructuring including legal fees
Restructuring including legal fees
Restructuring including legal fees
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Investment Income, Nonoperating, Total
Interest and investment income
Investment Income, Nonoperating
Total prepaid expenses and other current assets
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Investments
Investments [Domain]
Commissions and Offering Expenses Payable
Commissions and Offering Expenses Payable
Commissions and Offering Expenses Payable
Number of operating segment
Number of Operating Segments
Sale of Stock
Sale of Stock [Domain]
Segment Reporting Disclosure [Text Block]
Segment Information
General and Administrative Expense, Total
General and administrative
General and Administrative Expense
Supplemental disclosure of non-cash financing activities:
Noncash Financing Items [Abstract]
Noncash financing items.
Prepayment to related party for collaboration agreement
Prepayment to related party for collaboration agreement
Prepayment To Related Party For Collaboration Agreement
Prepayment to related party for collaboration agreement.
Subsequent Event [Table]
Adjustments to Additional Paid in Capital, Warrant Issued
The purchase warrants were recorded as a liability
Repurchase of common stock
Repurchase of common stock
Repurchase of common stock
Restructuring Charges, Total
Restructuring Charges
Restructuring and other charges
Restructuring charge
Fair Value Asset Measured On Recurring Basis [Table]
Fair Value Asset Measured On Recurring Basis [Table]
Fair Value Asset Measured On Recurring Basis [Table]
Recently Issued Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Current deferred revenue
Deferred revenue
Contract with Customer, Liability, Current
Gain on disposal
Gain (Loss) on Disposition of Assets
Gain (Loss) on Disposition of Assets, Total
Long-Lived Assets Held-for-Sale, Name [Domain]
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, outstanding
Common Stock, Shares, Outstanding
Lease liability - operating lease
Operating Lease, Liability, Current
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Document Transition Report
Document Transition Report
Total operating expenses
Operating Expenses
Research and Development Expense
Research and Development Expense, Total
Research and development
Impairment Charge
Asset Impairment Charges
Asset Impairment Charges, Total
Statement of Cash Flows [Abstract]
Schedule Of Option Pricing Model At Issuance Table Text Block
Schedule Of Option Pricing Model At Issuance Table Text Block
Schedule of Assumptions Used in Determining Fair Value of Warrants
Stock Issued During Period, Value, New Issues
Proceeds from issuance of common stock in connection with at-the-market offering, net of issuance costs
Assets, Fair Value Disclosure [Abstract]
Assets:
Stockholders' Equity
Equity [Text Block]
Earnings Per Share [Text Block]
Net Income per Share
Net loss
Net Income(Loss)
Net income
Net income
Compensation included in restructuring charges
Compensation included in restructuring charges
Compensation included in restructuring charges
Common Stock Issuable Under Pre-Funded Warrants
Pre-Funded Warrants
Pre Funded Warrants [Member]
Pre-Funded Warrants.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Assets
Assets [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Weighted-average, risk free interest rate
Construction in Progress
Construction in Progress [Member]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
Ginkgo Collaboration
Ginkgo Bioworks Inc [Member]
Ginkgo Bioworks, Inc.
Common stock issuable under Ginkgo pre-funded warrants
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Research and Development Expense
Research and Development Expense [Member]
Deferred revenue balance
Deferred Revenue
Deferred Revenue, Total
Reduction in WorkForce
Reduction in WorkForce
Reduction in WorkForce
Restructuring Cost and Reserve [Line Items]
Revision of Prior Period [Domain]
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Prepaid research and development, net of current portion
Increase Decrease In Prepaid Research And Development Net Of Current Portion
Increase (decrease) in prepaid research and development net of current portion.
Effective Income Tax Rate Reconciliation [Line Items]
Share-Based Payment Arrangement [Abstract]
Total assets
Assets, Fair Value Disclosure
Purchase Warrants [Member]
Purchase Warrants [Member]
Purchase warrants
Sale of Stock
Sale of Stock [Axis]
Revenues, Total
Recognition of revenue
Revenue
Revenues
Net cash provided by investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Common stock and warrants purchase
Common Stock And warrants Purchase
Common Stock And warrants Purchase
Gain Contingencies [Table]
Gain Contingencies [Table]
Money market funds
Money Market Funds [Member]
Related Party
Related and Nonrelated Parties [Domain]
Income Taxes
Income Tax Disclosure [Text Block]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Number of securities with other than temporary impairment
Other Than Temporary Impairment Losses Investments Number Debt Securities Available For Sale
Other than temporary impairment losses investments number debt securities available for sale.
Warrants exercised
Warrants Exercised
Warrants exercised.
Pre fund warrant purchase description
Warrant or Right, Reason for Issuance, Description
Document Information [Table]
Restructuring Plan [Domain]
Legal Entity
Legal Entity [Axis]
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Income Tax Disclosure [Abstract]
Unrecognized tax benefits
Unrecognized Tax Benefits
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Measurement Frequency
Measurement Frequency [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Prepaid research and development
Prepaid Research And Development Current
Prepaid research and development, current.
Prepaid Research And Development Current
Trading Symbol
Trading Symbol
Property and Equipment, Net
Property, Plant and Equipment Disclosure [Text Block]
Schedule Of Related Party Transactions By Related Party [Table]
Related Party Transaction [Table]
Subsequent Event Type [Axis]
Revision of Prior Period, Adjustment [Member]
RestatementAdjustmentMember
Employee-related Liabilities, Current, Total
Payroll related
Employee-related Liabilities, Current
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected Term
Recurring
Fair Value, Recurring [Member]
Property, Plant and Equipment Assets Held-for-Sale Disclosure [Abstract]
Accumulated Deficit
Equity Components [Axis]
Nonoperating Income (Expense)
Other income (expense), net
Total other income, net
Equity Component
Equity Component [Domain]
Asset Class [Axis]
Long-Lived Assets Held-for-Sale [Line Items]
Proceeds from issuance of common stock and pre-funded warrants
Proceeds From Issuance Of Common Stock And Pre Funded Warrants
Proceeds from issuance of common stock and pre funded warrants.
Lease Improvements
Leasehold Improvements, Gross
Common Stock And Warrants [Member]
Common Stock And Warrants [Member]
Common Stock And Warrants
Prepaid Insurance
Prepaid insurance
Aggregate Purchase
Aggregate Purchase
Aggregate Purchase
Estimated project cost for access personal support and other services
Estimated Project Cost For Access Personal Support And Other Services
Estimated project cost For access personal support and other services.
Issuance of common stock under employee stock purchase plan, Shares
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Statement of Comprehensive Income [Abstract]
Maximum [Member]
Maximum
Liabilities, Fair Value Disclosure
Total liability
Statistical Measurement [Axis]
Prepaid Expense, Current, Total
Current pre-paid research and development
Prepaid Expense, Current
Common Stock, Value, Issued
250,000,000 shares authorized as of March 31, 2026 and December 31, 2025; 11,978,711 shares issued and 11,698,919 shares outstanding as of March 31, 2026 and 11,978,711 shares issued and 11,698,919 shares outstanding as of December 31, 2025
Payments on finance lease obligations
Finance Lease, Principal Payments
At-the-market Offering
At The Market Offering [Member]
At-the-market offering,
Research and milestone payment
Research And Milestone Payment
Research And Milestone Payment
Principles of Consolidation
Consolidation, Policy [Policy Text Block]
Current Liabilities
Current Liabilities [Member]
Current liabilities.
Laboratory Equipment
Equipment [Member]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Comprehensive income:
Share Repurchase
Share Repurchase [Text Block]
Share Repurchase [Text Block]
Disclosure of Long-Lived Assets Held-for-Sale [Table Text Block]
Assets Held for Sale
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
ESPP
Employee Stock Purchase Plan
Employee Stock [Member]
Entity Registrant Name
Entity Registrant Name
Gross unrealized losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Other Nonoperating Income (Expense), Total
Other Nonoperating Income (Expense)
Other income (expense)
Assets acquired under operating lease obligation.
Assets Acquired Under Operating Lease Obligation
Assets acquired under operating lease obligation
Subsequent Events [Abstract]
Azzur
Azzur Group Limited Liability Company [Member]
Azzur Group Limited Liability Company.
Income tax expense
Income tax expense
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Measurement Frequency
Measurement Frequency [Axis]
Asset, Held-for-Sale, Not Part of Disposal Group, Current, Total
Asset, Held-for-Sale, Not Part of Disposal Group, Current
Assets held for sale
Proceeds from issuance of common stock in connection with at-the-market offering, net of issuance costs
Proceeds from Issuance of Common Stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Underwritten Public Offering [Member]
Underwritten Public Offering
Underwritten public offering.
Warrants To Purchase Shares Of Common Stock
Warrants To Purchase Shares Of Common Stock
Warrants To Purchase Shares Of Common Stock
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Number of restricted stock awards granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Unvested Restricted Stock Awards [Member]
Unvested Restricted Stock Awards [Member]
Unvested Restricted Common Stock Awards
Total assets
Assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Income Statement [Abstract]
Restructuring Cost [Table]
Treasury Stock Share
Treasury Stock Share
Treasury stock, shares
Number of shares sold
Sale of common stock, shares
Proceeds from issuance of common stock in connection with at-the-market offering, net of issuance costs, Shares
Restructuring, Settlement and Impairment Provisions, Total
Restructuring, Settlement and Impairment Provisions
Impairment for in-process research and development
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net income (loss per share) - diluted
Diluted EPS
Schedule of Research and Development, General and Administrative Expenses, and Restructuring Charges are Significant Segment Expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Error Correction [Table]
City Area Code
City Area Code
Restructuring costs
Accured Restructuring cost
Accured Restructuring cost
Transaction Costs Allocated To Warrant Liabilities
Transaction Costs Allocated To Warrant Liabilities
Transaction costs allocated to warrant liabilities
Impairment losses
Impairment Losses Related to Real Estate Partnerships
Issuance of common stock under employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Segment Reporting Information [Line Items]
Issuance of restricted stock, shares
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Award Date [Axis]
Letter Of Credit Member
Letter of Credit [Member]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Operating Income (Loss)
Loss from operations
Award Date [Domain]
Accumulated Deficit
Retained Earnings [Member]
Consulting and Professional Services [Member]
Consulting and Professional Services [Member]
Consulting and professional services
Cash and Cash Equivalents
Cash and Cash Equivalents [Axis]
Share-Based Payment Arrangement, Noncash Expense, Total
Equity-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Total long-term liabilities
Liabilities, Noncurrent
Lease liability - operating lease, net of current portion
Operating Lease, Liability, Noncurrent
Quoted Prices in Active Markets for Identical Assets (Level 1)
Fair Value, Inputs, Level 1 [Member]
Class Of Stock [Line Items]
Class of Stock [Line Items]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Investments, Fair Value Disclosure, Total
Short-term investments
Investments, Fair Value Disclosure
U.S. government agency securities and treasuries
U S Treasury And Government Long Term Debt Securities [Member]
US treasury and government long-term debt securities.
Restructuring Charges [Member]
Restructuring charges: expense acceleration
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan [Member]
Nonoperating Income (Expense) [Abstract]
Other income:
Schedule of Potentially Common Shares Excluded from Calculation of Net Loss Per share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Corporate Debt Securities
Corporate Debt Securities [Member]
Income Tax Jurisdiction [Domain]
Clinical Research and External Costs [Member]
Clinical Research and External Costs [Member]
Clinical research and external costs
Debt Securities Available For Sale [Table]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Income Statement Location
Statement of Income Location, Balance [Domain]
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Furniture and Fixtures [Member]
Furniture and Fixtures
Jefferies, LLC
Jefferies L L C [Member]
Jefferies, LLC
Option Indexed to Issuer's Equity, Type
Option Indexed to Issuer's Equity, Type [Domain]
Entity Tax Identification Number
Entity Tax Identification Number
Error Correction [Text Block]
Revision of Previously Issued Financial Statements
Fair Value Asset Measured On Recurring Basis [Line Items]
Fair Value Asset Measured On Recurring Basis [Line Items]
Fair Value Asset Measured On Recurring Basis [Line Items]
Nature of Business
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Local Phone Number
Local Phone Number
Long-Lived Asset, Held-for-Sale [Table]
Employee unrecognized compensation expense
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Denominator:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Loss on purchase warrant liability
Loss on Purchase Warrant Liability
Loss on Purchase Warrant Liability
Accounting Policies [Abstract]
Increase (Decrease) In Fair Value Warrant Liability
Increase (Decrease) In Fair Value Warrant Liability
Change in fair value of warrant liability
Previously Reported [Member]
ScenarioPreviouslyReportedMember
Cancellation of restricted stock
Stock Issued During Period, Shares, Restricted Stock Award, Forfeited
Cancellation of restricted stock
ATM
At The Market [Member]
at the market.
Gross Unrealized Gain
CashEquivalentsAccumulatedGrossUnrealizedGain
CashEquivalentsAccumulatedGrossUnrealizedGain
Cash and Cash Equivalents [Member]
Cash and Cash Equivalents
Cash And Cash Equivalents Member
Class of Stock [Domain]
Commercial Paper
Commercial Paper [Member]
Shares available for future grants
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Employee unrecognized compensation cost, period of recognition
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Professional fees
Accrued Professional Fees, Current
Cash, Cash Equivalents, and Short-Term Investments, Total
Cash, cash equivalents, and short-term marketable securities
Cash, Cash Equivalents, and Short-Term Investments
Net Income (Loss) Available to Common Stockholders, Diluted [Abstract]
Numerator:
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Percentage Of Common Stock Ownership To Exercise Warrant
Percentage Of Common Stock Ownership To Exercise Warrant
Percentage Of Common Stock Ownership To Exercise Warrant
Entity Emerging Growth Company
Entity Emerging Growth Company