v3.26.1
Preferred Stock and Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
 3 Months Ended
Dec. 30, 2025
Nov. 13, 2025
Nov. 12, 2025
Sep. 20, 2024
Mar. 31, 2026
Mar. 31, 2025
Dec. 31, 2025
Jun. 10, 2025
Jun. 09, 2025
Dec. 31, 2024
Apr. 28, 2023
Class Of Stock [Line Items]                      
Common stock, shares authorized         300,000,000   300,000,000 300,000,000 200,000,000    
Common stock, shares issued         75,851,722   75,430,033        
Convertible preferred stock, shares authorized         5,000,000            
Convertible preferred stock, par value         $ 0.001            
Underwriting Agreement [Member] | Leerink Partners LLC [Member]                      
Class Of Stock [Line Items]                      
Proceeds from issuance offering   $ 57.5                  
Net proceeds after deducting offering costs     $ 53.6                
Series X1 Non-voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Convertible preferred stock, shares authorized         515,000   515,000        
Convertible preferred stock, par value         $ 0.001   $ 0.001        
Convertible preferred stock, shares issued         110,086   110,086        
Convertible preferred stock, shares outstanding         110,086 110,086 110,086     110,086  
Series X Non-Voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Convertible preferred stock, shares authorized         10,000   10,000        
Convertible preferred stock, par value         $ 0.001   $ 0.001        
Convertible preferred stock, shares issued         4,422   4,422        
Convertible preferred stock, shares outstanding         4,422 4,422 4,422     4,422  
Common Stock [Member]                      
Class Of Stock [Line Items]                      
Shares of common stock issued upon conversion of each share of preferred stock         55.5556   55.5556        
Common Stock [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                      
Class Of Stock [Line Items]                      
Warrant exercise price per share     $ 0.001                
Common Stock Warrants and Pre-Funded Warrants [Member]                      
Class Of Stock [Line Items]                      
Warrants available for exercise         51,781,090            
Warrant exercise price per share         $ 3            
Private Placement Warrants [Member] | Accredited Investor [Member]                      
Class Of Stock [Line Items]                      
Warrant exercise price per share                     $ 3
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] | Accredited Investor [Member]                      
Class Of Stock [Line Items]                      
Common stock, shares issued                     15,151,518
Common stock warrants exercisable                     15,151,518
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] | Accredited Investor [Member]                      
Class Of Stock [Line Items]                      
Common stock, shares issued                     909,088
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] | Accredited Investor [Member]                      
Class Of Stock [Line Items]                      
Common stock, shares issued                     1,727,400
2025 Warrant Exchange Agreement [Member]                      
Class Of Stock [Line Items]                      
Conversion of stock, shares issued 4,203,764                    
2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member]                      
Class Of Stock [Line Items]                      
Common stock warrants exercisable 4,203,764                    
Cancelled common stock shares delivered in exchange of warrants 4,203,764                    
Underwritten Public Offering [Member] | Underwriting Agreement [Member]                      
Class Of Stock [Line Items]                      
Conversion of stock, shares issued     15,152,485                
Stock price per share     $ 1.65                
Warrant exercise price per share     $ 1.649                
Maximum [Member] | Common Stock [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                      
Class Of Stock [Line Items]                      
Common stock warrants exercisable     15,151,515                
Maximum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Conversion of preferred stock, conversion blocker, percent           9.99%          
Maximum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Conversion of preferred stock, conversion blocker, percent         9.99%            
Maximum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                      
Class Of Stock [Line Items]                      
Options issued to purchase common stock     4,545,600                
Maximum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                      
Class Of Stock [Line Items]                      
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage     19.99%                
Maximum [Member] | 2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                      
Class Of Stock [Line Items]                      
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage 19.99%                    
Minimum [Member]                      
Class Of Stock [Line Items]                      
Percentage of exchange offer by third party to common stockholders         50.00%            
Minimum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Conversion of preferred stock, conversion blocker, percent           9.90%          
Minimum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                      
Class Of Stock [Line Items]                      
Conversion of preferred stock, conversion blocker, percent         9.90%            
Minimum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                      
Class Of Stock [Line Items]                      
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage     4.99%                
Minimum [Member] | 2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                      
Class Of Stock [Line Items]                      
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage 4.99%                    
Guggenheim Securities LLC [Member] | Maximum [Member] | Equity Distribution Agreement [Member]                      
Class Of Stock [Line Items]                      
Proceeds from issuance of common stock       $ 75.0