0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Organization and Operations link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Basis of Presentation, Liquidity and Risks and Uncertainties link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Critical Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Short-term Investments and Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Certain Balance Sheet Items link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Related Party Transactions link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Collaborative Agreements link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Geneos Therapeutics, Inc. link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Basis of Presentation, Liquidity and Risks and Uncertainties (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Short-term Investments and Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Certain Balance Sheet Items (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Stockholders' Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Basis of Presentation, Liquidity and Risks and Uncertainties (Details) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Short-term Investments and Fair Value Measurements - Summary of Available-for-sale Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Short-term Investments and Fair Value Measurements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Short-term Investments and Fair Value Measurements - Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Short-term Investments and Fair Value Measurements - Changes in Level 3 Asset Values (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Short-term Investments and Fair Value Measurements - Schedule of Assumptions Used To Estimate The Fair Value Of Warrants (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Short-term Investments and Fair Value Measurements - Changes In Fair Value Of The Company’s Total Level 3 Financial Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Certain Balance Sheet Items - Prepaid and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Certain Balance Sheet Items - Accounts Payable and Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Stockholders' Equity - Summary of Authorized and Issued Common and Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Stockholders' Equity - Offering of Common Stock, Warrants, and Pre-funded Warrants (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Stockholders' Equity - Common Stock Warrants (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Stockholders' Equity - At-The-Market Sales Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Stockholders' Equity - Stock Options and Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Net Loss Per Share - Anti-dilutive (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Stock-Based Compensation - Weighted Average Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Stock-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Stock-Based Compensation - Significant Assumption Used in Monte Carlo Simulation Method (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Related Party Transactions (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Lease Payments (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Lease Payments (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Collaborative Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Geneos Therapeutics, Inc. (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Segment Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Subsequent Events (Details) link:presentationLink link:calculationLink link:definitionLink