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Plan Name [Axis] Hanmi Licensing Agreement [Member] Hanmi Licensing Agreement. Entity Current Reporting Status Negative shareholder's equity Negative Shareholder's Equity Negative shareholder's equity. Operating Expenses [Abstract] Operating expenses: Level 2 [Member] Fair Value, Inputs, Level 2 [Member] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Document Fiscal Period Focus Loan interest rate Debt Instrument, Interest Rate, Stated Percentage Entity Shell Company Other accrued expenses Other Accrued Liabilities, Current Minimum amount available under single advance Minimum Amount Available Under Single Advance Minimum amount available under single advance. Keystone Capital Partners, LLC [Member] Keystone Capital Partners, LLC. Common Stock, Share issued Common Stock, Shares, Issued Asset Class [Domain] September Five Two Thousand Twenty Nine [Member] September five two thousand twenty nine. September 5, 2029 [Member] Statement [Table] Prepaid expenses Increase (Decrease) in Prepaid Expense Prepaid expenses Interest on related party loan payable Interest on related party loan payable. Interest on related party loan payable Respective affiliates, for a consideration Payments to Acquire Businesses, Gross Statement [Line Items] Warrant [Member] Warrant [Member] Entity Filer Category Liabilities and Equity Total liabilities and shareholders' deficit Payables and Accruals [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Debt Instrument, Frequency of Periodic Payment Interest payments frequency Series A Warrants [Member] Series A Warrants [Member] Series A warrants. Hanmi Facility Agreement [Member] Hanmi Facility Agreement. January Thirty Two Thousand And Twenty Nine [Member] January thirty two thousand and twenty nine. January 30, 2029 [Member] Cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Shares Issued, Price Per Share Shares Issued, Price Per Share (in dollars per share) Common share exchange price Subsequent Event [Line Items] January Thirty One Thousand And Twenty Nine [Member] January thirty one thousand and twenty nine. January 31, 2029 [Member] Non-current assets: Assets, Noncurrent [Abstract] Two thousand twenty three committed equity facility. Two Thousand Twenty Three Committed Equity Facility [Member] 2023 Committed Equity Facility [Member] Loan payable maturity date. Loan payable maturity date Significant accounting policies Significant Accounting Policies [Text Block] Class Of Warrant Or Right Exercise Price Of Warrants Or Rights Two Class of warrant or right exercise price of warrants or rights two. Exercise price Restricted cash equivalents Restricted Cash Equivalent Restricted Cash Equivalents, Total Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Exercised Share based compensation arrangement by share based paymet award weighted average exercise price exercised. Weighted average exercise price, Exercised Maximum Number of Advances Maximum number of advances. Maximum number of advances Vesting [Domain] Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Stock options granted in the period (in shares) Percentage of shares outstanding for issuance of warrant. Percentage of shares outstanding for issuance of warrant Percentage of shares outstanding Schedule of Earnings Per Share, Basic and Diluted Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Investment, Name [Axis] Earnings Per Share, Basic, Total Earnings Per Share, Basic Net loss per common share - basic Net loss per common share, basic Stock Issued During Period, Value, Licensing Fee Common shares issued pursuant to the Hanmi licensing fees Value of stock issued as a result of licensing fee. Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Outstanding, options (in shares) Outstanding, options (in shares) Current liabilities Liabilities, Current Total current liabilities Investment for ownership interest Equity Method Investment, Quoted Market Value Class Of Warrant Or Right Outstanding One Class of warrant or right outstanding one. Shares issuable upon exercise Information regarding continuing vesting options with no service requirement. Continuing Vesting Options with No Service Requirement [Member] Equity, Attributable to Parent [Abstract] Shareholders' deficit: Entity Small Business Accrued liabilities Increase (Decrease) in Accrued Liabilities, Total Increase (Decrease) in Accrued Liabilities Accumulated deficit Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit) Accumulated deficit Placement agent warrants. Placement Agent Warrants [Member] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Forfeited, options (in shares) Employee Stock Purchase Plan [Member] Employee stock purchase plan. ESPP [Member] Sale of Stock, Price Per Share Sale of stock price per share Note To Financial Statement Details Textual Note To Financial Statement Details Textual Stock-based compensation Share-Based Payment Arrangement [Text Block] Organization, Consolidation and Presentation of Financial Statements [Abstract] Restricted Cash Disclosure [Text Block] Restricted Cash Disclosure. Restricted Cash Two Thousand Twenty Five Committed Equity Facility [Member] Two thousand twenty five committed equity facility. 2025 Committed Equity Facility [Member] Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Exercisable Share based compensation arrangement by share based paymet award weighted average exercise price exercisable. Weighted average exercise price, Exercisable Amendment Flag Warrants to purchase common shares, number of warrants Class of Warrant or Right, Number of Securities Called by Warrants or Rights Hanmi Pharmaceuticals Co., Ltd. [Member] Hanmi Pharmaceuticals Co Ltd [Member] Hanmi Pharmaceuticals Co., Ltd. Chief Executive Officer [Member] CEO [Member] Entity Address, Postal Zip Code Share Based Compensation Arrangement By Share Based Paymet Award Weighted Average Exercise Price Granted Share based compensation arrangement by share based paymet award weighted average exercise price granted. Weighted average exercise price, Issued Interest on Related Party Loan Payable [Member] Interest on Related Party Loan Payable [Member] Interest on related party loan payable. Warrants Disclosure [Text Block] Warrants. Warrants Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Cash used in operating activities Change in operating lease liability Increase (Decrease) in Operating Lease Liability Common Stock [Member] Common Shares [Member] Public Offering [Member] Represents information pertaining to public offering. Public Offering [Member] Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Related Party Transaction, Date Transaction date Loan is repayable date Series B warrants. Series B Warrants [Member] Series B Warrants [Member] Entity Address, Address Line One Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Fair Value Hierarchy and NAV [Axis] Earnings Per Share [Abstract] Foreign currency Foreign Currency Transactions and Translations Policy [Policy Text Block] Right-of-use assets, operating leases Operating Lease, Right-of-Use Asset Right-of use assets, operating leases, net Transaction cost including placement agent fees and professional fees Transaction Cost Including Placement Agent Fees and Professional Fees Transaction cost including placement agent fees and professional fees. Class of Warrant or Right [Axis] Document Type Collaborative Arrangement and Arrangement Other than Collaborative [Axis] The amount of accrual of interest on investments. apto_InterestAccruedOnInvestments Accrued interest on investments Warrants issued Warrants Issued Warrants issued. Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Entity Central Index Key Foreign exchange gain/(loss) Foreign exchange loss Stock issuance program authorized shares Stock Issuance Program Authorized Shares Stock issuance program authorized shares. Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Increase (decrease) in cash and restricted cash Subsequent Event Type [Domain] Noncash Operating Lease Expense Noncash operating lease expense. Noncash operating lease expense Proceeds from Issuance of Warrants Cash proceeds Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Statement-Statement-Note-11-Stockbased-Compensation-Stock-Option-Transactions-Details Note 14 - Stock-based Compensation - Stock Option Transactions (Details) Amount Agreed To Pay For Reasonable Expenses Under Purchase Agreement Amount agreed to pay for reasonable expenses under purchase agreement. Amount agreed to pay for reasonable expenses under purchase agreement Retention bonuses Restructuring and Related Cost, Expected Cost Restructuring and Related Cost, Expected Cost, Total Second Back-End Commitment Shares [Member] Second Back-End Commitment Shares [Member] Second back-end commitment shares. Repayments of Related Party Debt Repayment of loan with related party Accrued liabilities Accrued Liabilities, Current Total The amount of interest expense related to lease liabilities Interest on lease liabilities Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Current Fiscal Year End Date Newbridge Warrants [Member] Newbridge warrants. Document Quarterly Report Hanmi Loan Agreement. Hanmi Loan Agreement [Member] Information pertaining to the 2020 ATM Offering. The 2020 ATM Offering [Member] The 2020 ATM Offering Weighted average exercise price, Beginning Weighted average exercise price, Ending Share Based Compensation Arrangement By Share Based Paymet Award Non Option Outstanding Weighted Average Exercise Price Share based compensation arrangement by share based paymet award non option outstanding weighted average exercise price. Entity Address, State or Province Investment, Name [Domain] Investment Owned, Balance, Shares Number of common shares held Common stock capital shares reserved for future issuance Common Stock, Capital Shares Reserved for Future Issuance Shares available for future issuance Class of Warrant or Right [Domain] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Share-based Payment Arrangement, Expensed and Capitalized, Amount Professional fees Professional Fees Common shares issued upon exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Subsequent Event [Member] Stock Issued During Period Value Debt Conversion Stock issued during period value debt conversion. Common shares issued pursuant to Hanmi debt conversion Other Assets, Noncurrent Other long-term assets Common warrants offering price Common Warrants Combined Offering Price Common warrants combined offering price. H.C. Wainwright [Member] H C Wainwright [Member] H.C. Wainwright. Related Party Transaction [Axis] AOCI Attributable to Parent [Member] Warrants And Rights Outstanding Maturity Date One Warrants and rights outstanding maturity date one. Expiration date Repayment date Debt Instrument, Maturity Date Minimum [Member] Minimum [Member] Current assets: Assets, Current [Abstract] Nasdaq Listing Rule, minimum requirement for stockholders' equity Nasdaq Listing Rule Minimum Requirement For Stockholders Equity Nasdaq listing rule minimum requirement for stockholders equity. Capital raise, amount Capital Raise Amount Capital raise amount. Level 3 [Member] Fair Value, Inputs, Level 3 [Member] Unrealized Gain (Loss) on Investments Unrealized gain on short-term investment Cost of offering Cost Of Offering Cost of offering. Assets Measured on a Recurring Basis Fair Value, Assets Measured on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Current liabilities: Liabilities, Current [Abstract] Amended Facility Agreement [Member] Amended facility agreement. HM43239 [Member] Information related to HM43239. Related Party Transactions [Abstract] Balance (in shares) Shares, Outstanding Balance (in shares) The 2023 equity facility. The 2023 Equity Facility [Member] General and Administrative Expense [Member] Stockholders' Equity, Reverse Stock Split Reverse stock split Short-Term Advance Short-Term Debt Common Stock, No Par Value Common Stock, No Par Value Common shares, no par value New Incentive Plan [Member] New Incentive Plan [Member] The 2022 ATM Offering [Member] The 2022 Atm Offering [Member] The 2022 atm offering. Non-current liabilities: Liabilities, Noncurrent [Abstract] Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Effect of exchange rate fluctuations on cash High Interest Savings Account [Member] Bank Time Deposits [Member] High Interest Savings Accounts [Member] Interest Income (Expense), Operating Interest Income (Expense), Operating, Total Interest (expense) income Weighted Average Number of Shares Outstanding, Basic, Total Weighted Average Number of Shares Outstanding, Basic Weighted-average number of common shares outstanding - basic Weighted-average number of common shares outstanding, basic Restrictions on Cash and Cash Equivalents [Table] Statement-Statement-Note-11-Stockbased-Compensation-Sharebased-Payment-Expense-Details Note 14 - Stock-based Compensation - Share-based Compensation Expense (Details) Loan payable maturity date Long-Term Debt, Maturity Date Warrants And Rights Outstanding Maturity Date Two Warrants and rights outstanding maturity date two. Expiration date Initial Commitment Shares [Member] Initial Commitment Shares [Member] Initial commitment shares. Subsequent events Subsequent Events [Text Block] Long-Term Debt, Total Long-Term Debt Loan payable Related Party Transactions Disclosure [Text Block] Related party transactions Cash Cash Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Percentage of common shares outstanding. Percentage of Common Shares Outstanding Percentage of common shares outstanding. Negative shareholder's equity Positive shareholder's equity Equity, Attributable to Parent Balance Balance Total shareholders' deficit Basis of Accounting, Policy [Policy Text Block] Basis of presentation - going concern Statement of Stockholders' Equity [Abstract] Significant accounting policies, estimates and judgments Use of Estimates, Policy [Policy Text Block] Equity Method Investment [Table] Over-Allotment Option [Member] Over-Allotment Option [Member] Entity Address, Address Line Two Fair value measurements and financial instruments Fair Value Disclosures [Text Block] Debt Modification Description Debt modification description. Debt modification description Warrants and Rights Note Disclosure [Abstract] March Five Two Thousand And Twenty Six [Member] March five two thousand and twenty six. March 5, 2026 [Member] Schedule of Accrued Liabilities [Table Text Block] Schedule of Accrued Liabilities Other current assets Other Assets, Current Payment of supply costs. Payment Of Supply Costs Payment of supply costs Hanmi Second Amended Facility Agreement [Member] Hanmi second amended facility agreement . Plan Name [Domain] Increase (Decrease) in Other Operating Assets Other current assets Increase (Decrease) in Other Operating Assets, Total Other assets Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Entity [Domain] Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Exercisable Weighted Average Remaining Contractual Life Share based compensation arrangement by share based payment award non option equity instruments exercisable weighted average remaining contractual life. Weighted average remaining contractual life (years) Percentage of investment Percentage of ownership common shares outstanding Equity Method Investment, Ownership Percentage Warrants outstanding Shares Issuable Upon Exercise Shares issuable upon exercise Related and Nonrelated Parties [Axis] Statement-Statement-Note-11-Stockbased-Compensation-Tables Note 11 - Stock-based Compensation Class of Warrant or Right [Table] Reverse Stock Split [Policy Text Block] Reverse Stock Split [Policy Text Block] Reverse stock split Entity Address, City or Town Security Exchange Name Maximum Amount Available Under Single Advance Maximum amount available under single advance. Maximum amount available under single advance The percent maximum payroll deduction under an employee stock purchase plan. apto_EmployeeStockPurchasePlanMaximumPayrollDeductionPercent Employee Stock Purchase Plan, Maximum Payroll Deduction, Percent Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted Common shares issuable upon exercise, Issued Information related to vested options. Vested Options [Member] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Statistical Measurement [Domain] Warrants to purchase common shares, exchange price Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price Assets, Current Total current assets Share-Based Payment Arrangement, Expense Share-Based Payment Arrangement, Expense Document Period End Date Equity Method Investments and Joint Ventures [Abstract] Title and Position [Axis] Fair Value Hierarchy and NAV [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number January 30, 2029 [Member] January Thirty Two Thousand And Twenty Nine, One [Member] January thirty two thousand and twenty nine. Statement of Financial Position [Abstract] Two Thousand Twenty Five ATM Facility [Member] Two Thousand Twenty Five ATM Facility [Member] The 2025 ATM Offering [Member] Amount received cash equal to shareholder Amount received cash equal to shareholder Vesting [Axis] Working capital Working Capital Working capital. Warrants and Rights Outstanding, Maturity Date Warrants, maturity date Expiration date Summary of Number of Outstanding Warrants by Exercise Price and Date of Expiration Schedule Of Number Of Outstanding Warrants by exercise Price And Date Of Expirations Schedule of number of outstanding warrants by exercise price and date of expirations. Liabilities Total liabilities Registered Direct Offering [Member] Registered direct offering. Restricted Cash and Cash Equivalent Item [Line Items] Restricted Cash and Cash Equivalents Items [Line Items] Restricted Cash Restricted cash Restricted Cash, Total Weighted-average common shares - diluted Weighted Average Number of Shares Outstanding, Diluted, Total Weighted-average number of common shares outstanding - diluted Weighted-average number of common shares outstanding, diluted Securities Act File Number Initial Proceeds from Related Party Debt Initial proceeds from related party debt. Initial proceeds from related party debt Cover [Abstract] United States Treasury Bills [Member] US Treasury Securities [Member] Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized (in shares) Sale of Stock [Domain] General and administrative General and Administrative Expense, Total General and Administrative Expense Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract] Adjustments to reconcile net loss to cash used in operating activities: The gross amount of cash inflow received from the issuance of common stock, before stock issuance costs. apto_ProceedsFromIssuanceOfCommonStockGross Proceeds from Issuance of Common Stock, Gross Revenue Revenue from Contract with Customer, Including Assessed Tax Subsequent Event [Table] First Back-End Commitment Shares [Member] First Back-End Commitment Shares [Member] First back-end commitment shares. Cash transaction costs Cash Transaction Costs Cash transaction costs. Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price New Accounting Pronouncements, Policy [Policy Text Block] Recent accounting pronouncements Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Schedule of Future Minimum Payments of Lease Liabilities Underwriting costs (as percent) Percentage of Underwriting Cost Percentage of underwriting cost. Depreciation of property and equipment Depreciation Depreciation, Total Common Stock, Shares Outstanding Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding Current portion of lease liability, operating leases Operating Lease, Liability, Current Lease liability, current portion Less: current portion of lease liability Document Transition Report Operating Expenses Total operating expenses Accrued Liabilities, Current [Abstract] Research and development Research and Development Expense, Total Research and Development Expense The 2023 CMPO [Member] The 2023 CMPO [Member] The 2023 CMPO. Statement of Cash Flows [Abstract] Alliance Global Partners [Member] Alliance Global Partners. Stock Issued During Period, Value, New Issues Cash proceeds from issuing shares Common shares issued under 2025 ATM/ 2023 Committed Equity Facility Share-based Payment Arrangement, Option, Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Share capital Equity [Text Block] Common share exercise price Shares, Issued Share-based Payment Arrangement, Vesting and Redemption of the RSUs Granted Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Net loss for the period Net loss and comprehensive loss Net loss and comprehensive loss Warrants expiration period Warrants, Remaining contractual life Warrants and Rights Outstanding, Term The amount of research and development liabilities classified as current. Accrued research and development expenses Premium share price (as a percent) Premium Share Price Percent Premium share price percent. Operating Lease, Payments Operating lease payments Lease payment per month Cash flows from operating leases Document Fiscal Year Focus Debt Conversion, Converted Instrument, Shares Issued Common shares converted Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Exercisable Number Share based compensation arrangement by share based payment award non option equity instruments exercisable number. Common Shares Issuable upon Exercise, Exercisable Class Of Warrant Or Right Outstanding Two Class of warrant or right outstanding two. Shares issuable upon exercise Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Cash flows from investing activities: Accounts Payable, Current, Total Accounts Payable, Current Accounts payable Statement-Statement-Note-9-Lease-Liability-Tables Note 9 - Commitments and Contingencies Keystone [Member] Keystone [Member] Keystone. Interest Expense, Long-Term Debt, Total Interest Expense, Long-Term Debt Interest expense Research and Development Expense [Member] Total Accrued Liabilities Current Net Accrued liabilities current net. Short-Term Advance from CEO [Member] Short-term advance from CEO. Short-Term Advance from CEO [Member] Debt Conversion, Converted Instrument, Amount Conversion of loan payable with related party to common shares Information pertaining to the 2020 ATM Offering. The 2020 ATM Offering [Member] Convertible Debt Convertible Debt, Total Convertiable debt amount November Twenty Five Two Thousand Twenty Nine [Member] November twenty five two thousand twenty nine. November 25, 2029 [Member] Fair Value Disclosures [Abstract] Commitments and Contingencies Disclosure [Abstract] Loan payable to related parties, non-current. Loan payable to related parties, Non-current Loan payable to related party License Fee, Total apto_LicenseFeeTotal Represents total license fee. Change In Fair Value Of Warrant Liability Change in fair value of warrant liability. Change in fair value of warrants Interest Expenses Related Party Interest expenses related party. Interest expense, related party Interest expense, related party Derivative Instrument [Axis] Share-Based Payment Arrangement [Abstract] Stock Issued During Period Shares Debt Conversion Stock issued during period shares debt conversion. Common shares issued pursuant to Hanmi debt conversion (in shares) Assets, Fair Value Disclosure Assets, Fair Value Disclosure, Total Assets, Fair Value Disclosure Sale of Stock [Axis] Schedule of Share-based Payment Award, Options, Grants in Period Tabular disclosure of share options granted during the period. Schedule of Share-based Payment Award, Options, Grants in Period [Table Text Block] Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Cash provided by investing activities Private Placement [Member] Private Placement [Member] Commitment Shares [Member] Commitment Shares [Member] Commitment shares. Statement-Statement-Note-7-Fair-Value-Measurements-And-Financial-Instruments-Tables Note 7 - Fair Value Measurements and Financial Instruments Title of 12(b) Security Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted average exercise price, Forfeited/expired Related and Nonrelated Parties [Domain] January 2024 Public Offering [Member] January Two Thousand And Twenty Four Public Offering [Member] January two thousand and twenty four public offering. Class of Warrant or Right [Line Items] The percent of cash commission payable to the broker of a stock issuance. apto_StockIssuancePercentOfCashCommissionToBroker Stock Issuance, Percent of Cash Commission to Broker Legal Entity [Axis] cash flows pursuant to the revised cash flows pursuant to the revised Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Change in operating assets and liabilities: Notes To Financial Statements Abstract Notes To Financial Statements [Abstract] Amount of stock issuance plan authorized. apto_StockIssuanceProgramAuthorizedAmount Stock Issuance Program, Authorized Amount Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding, weighted average exercise price (in dollars per share) Outstanding, weighted average exercise price (in dollars per share) Fair Value, Recurring and Nonrecurring [Table] Additional Paid-in Capital [Member] Statement of Income Location, Balance [Axis] Trading Symbol Summary of Weighted Average Remaining Term of Leases and Weighted Average Discount Rate Tabular disclosure of lessee's operating lease liability and weighted average of operating lease liability. Lessee, Operating Lease Liability and Weighted Average [Table Text Block] Subsequent Event Type [Axis] Supply agreement. Supply Agreement [Member] Accrued personnel related costs Employee-related Liabilities, Current, Total Employee-related Liabilities, Current Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Cash flows from financing activities: Annual Escalation Rate Annual escalation rate. Annual escalation rate Accrued liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Future milestone payments. Future Milestone Payments Future milestone payments Schedule of Equity Method Investments [Line Items] Equity Components [Axis] Second Tranche [Member] Equity Method Investment Second Tranche [Member] Equity method investment second tranche. Nonoperating Income (Expense) Total other expenses Equity Component [Domain] Asset Class [Axis] June 2024 Registered Direct Offering [Member] June 2024 Registered Direct Offering [Member] June 2024 Registered Direct Offering. The 2025 A T M Offering [Member] The 2025 ATM Offering. The 2025 ATM Offering [Member] Shares issued under ESPP Common shares issued under the ESPP plan (Shares) Common shares issued under the ESPP (shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year) Interest On Loan Payable To Related Party Interest on loan payable to related party. Interest on loan payable to related party Maximum [Member] Maximum [Member] Statement-Statement-Note-8-Accrued-Liabilities-Tables Note 8 - Accrued Liabilities Liabilities, Fair Value Disclosure Liabilities, Fair Value Disclosure, Total Statistical Measurement [Axis] Total Prepaid expenses Prepaid Expense, Current Common shares, no par value, unlimited authorized shares, 2,552,429 issued and outstanding as of March 31, 2026 and December 31, 2025 Common shares, no par value, unlimited authorized shares, 2,552,429 issued and outstanding as of March 31, 2026 and December 31, 2025, respectively Cash and Cash Equivalents [Abstract] Basis of consolidation Consolidation, Policy [Policy Text Block] Loan Payable to Related Party [Member] Loan payable to related party. Loan Payable to Related Party [Member] Offered shares. Offered Shares [Member] Offered Shares [Member] Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Exercised Common shares issuable upon exercise, Exercised Entity Registrant Name Lessee Disclosure [Abstract] Other Nonoperating Income (Expense) Other Nonoperating Income (Expense), Total Other (expense) income, net Other (expense) income, net Additional paid-in capital Additional Paid in Capital, Total Additional Paid in Capital Interest on Related Party Loan Payable, Noncurrent Interest on related party loan payable. Interest on related party loan payable Subsequent Events [Abstract] Proceeds from Issuance of Common Stock Issuance of common shares under the ESPP share purchase Issuance of common shares Entity Common Stock, Shares Outstanding Concentration of risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Lease term Lessee, Operating Lease, Remaining Lease Term Proceeds From Issuance Of Common Stock and Warrants Proceeds from issuance of common stock and warrants. Issuance of common shares and warrants Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated Other Comprehensive Income (Loss), Net of Tax Number of options, Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period January Thirty Two Thousand And Twenty Eight [Member] January thirty two thousand and twenty eight. January 30, 2028 [Member] Assets Total assets Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term (Month) Income Statement [Abstract] 2023 Committed Equity Facility [Member] 2023 Committed Equity Facility [Member] 2023 committed equity facility. Pre-Funded Warrants [Member] Pre Funded Warrants [Member] Pre-funded warrants. Number of shares sold Sale of Stock, Number of Shares Issued in Transaction Payments for License Fee apto_PaymentsForLicenseFee Represents cash outflow for license fee. Common shares issued Common shares issued (in shares) Common shares issued under 2025 ATM/ 2023 Committed Equity Facility (in shares) Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Net loss per common share - diluted Net loss per common share, diluted Debt Conversion, Original Debt, Amount Convertible debt conversion Title and Position [Domain] City Area Code November Two Thousand Twenty Four Public Offering [Member] November 2024 public offering. November 2024 Public Offering [Member] Proceeds from Lines of Credit Proceeds from Lines of Credit, Total Total received Tuspetinib Licensing Agreement [Member] Tuspetinib Licensing Agreement. Debt Instrument, Face Amount Loan agreement amount Additional proceeds from related party debt Additional Proceeds from Related Party Debt Additional proceeds from related party debt. Stock Issued During Period, Value, Employee Stock Purchase Plan Common shares issued under the ESPP Property, Plant and Equipment, Net, Total Property, Plant and Equipment, Net Property and equipment, net Officer [Member] Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Cash and restricted cash, beginning of period Cash and restricted cash, end of period Retained Earnings [Member] Assets, Noncurrent Total non-current assets Share-Based Payment Arrangement, Noncash Expense, Total Share-Based Payment Arrangement, Noncash Expense Stock-based compensation Liabilities, Noncurrent Total non-current liabilities Level 1 [Member] Fair Value, Inputs, Level 1 [Member] Class of Stock [Line Items] Disclosure Text Block [Abstract] Notes to Financial Statements Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Cash provided by financing activities Lease, Cost [Table Text Block] Summary of Operating Lease Costs and Operating Cash Flows from Operating Leases Debt Conversion Agreement [Member] Debt conversion agreement. Short term investments Investments, Fair Value Disclosure Investments, Fair Value Disclosure, Total Summary of Warrant Activity Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Nonoperating Income (Expense) [Abstract] Other income (expenses): Derivative Contract [Domain] Pre-Funded warrants exercised. Pre-Funded Warrants exercised Pre-Funded warrants exercised Placement Agent Fees Placement agent fees. Placement agent fees Entity Interactive Data Current June three two thousand and twenty nine [Member] June three two thousand and twenty nine. June 3, 2029 [Member] Statement of Income Location, Balance [Domain] Costs and Expenses, Related Party Expenses Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Cash flows from operating activities: Proceeds from Related Party Debt Proceeds from loan payable with related parties Proceeds from loan payable with related party Interest expense paid Debt Instrument, Periodic Payment, Interest Entity Tax Identification Number Reporting entity Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Net proceeds Proceeds from Issuance or Sale of Equity Proceeds from Issuance or Sale of Equity, Total Proceeds of sale stock Local Phone Number Related Party Transaction [Domain] Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures Common shares issuable upon exercise, Forfeited/expired Class Of Warrant Or Right Exercise Price Of Warrants Or Rights Three Class of warrant or right exercise price of warrants or rights three. Exercise price Accounting Policies [Abstract] Financing costs including underwriting costs, professional fees and recognition of deferred financing costs Financing Costs Including Underwriting Costs, Professional Fees and Recognition of Deferred Financing Costs Financing costs including underwriting costs, professional fees and recognition of deferred financing costs. Debt Conversion, Description Debt conversion, description Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Cash and investment Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-Term Investments, Total Stock, Class of Stock [Table] Hanmi Private Placement [Member] Hanmi private placement. Common stock, Shares authorized Negative working capital Negative Working Capital Negative working capital. Entity Emerging Growth Company Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term