Document and Entity Information Document Type Document Quarterly Report Document Period End Date Document Transition Report Entity File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Adress Line Two Entity Address, City or Town Entity Address State Or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Ex Transition Period Entity Shell Company Title of 12(b) Security Trading Symbol Security Exchange Name Entity Common Stock, Shares Outstanding Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Condensed Consolidated Balance Sheets Statement [Table] Statement [Line Items] Statement Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Short-Term Investments Short-term investments Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Total current assets Property, Plant and Equipment, Net Property and equipment, net Operating Lease, Right-of-Use Asset Operating lease right-of-use assets, net Long-Term Investments Long-term investments Other Assets, Noncurrent Other non-current assets Total other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and Stockholders' Equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Total accrued expenses Accrued expenses Operating Lease, Liability, Current Operating lease liabilities, current Liabilities, Current Total current liabilities Liabilities, Noncurrent [Abstract] Long-term liabilities: Amount of royalty obligation classified as non-current. Royalty Obligation, Non Current Royalty obligation Secured Long-Term Debt, Noncurrent Senior secured term loan, net Notes Payable, Noncurrent Convertible senior notes, net Operating Lease, Liability, Noncurrent Operating lease liabilities, less current portion Liabilities, Noncurrent Total long-term liabilities Liabilities Total liabilities Commitments and Contingencies. Commitments and contingencies (Note 13) Equity, Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, par value $0.0001 per share; 25,000,000 shares authorized and no shares issued and outstanding as of March 31, 2026 and December 31, 2025 Common Stock, Value, Issued Common stock, par value $0.0001 per share; 175,000,000 shares authorized at March 31, 2026 and December 31, 2025, respectively; 62,383,377 and 54,485,518 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Retained Earnings (Accumulated Deficit) Accumulated deficit Accumulated deficit Equity, Attributable to Parent Balance at end Balance at the beginning Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollar per share) Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value (in dollar per share) Common Stock, Shares Authorized Common stock, shares authorized Common stock, shares authorized (in shares) Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common Stock, shares outstanding Condensed Consolidated Statements of Operations and Comprehensive Loss Revenues [Abstract] Revenue: Revenue from Contract with Customer, Excluding Assessed Tax License and collaboration revenue Revenue Revenues Total revenue Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development expenses Research and development General and Administrative Expense General and administrative Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Nonoperating Income (Expense) [Abstract] Other income (expense), net: The interest expense recognized during the period on account of royalty obligation. Interest Expense, Royalty Interest expense on royalty obligation Interest Expense, Debt Interest expense on senior secured term loan Interest expense on senior secured term loan Total interest expense Investment Income, Interest Interest income Other Nonoperating Income (Expense) Other (expense) income, net Nonoperating Income (Expense) Total other income (expense), net Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest Loss before income taxes Income Tax Expense (Benefit) Income tax provision (benefit) Net loss Net loss Net loss Earnings Per Share, Basic Net loss per share - basic (in dollars per share) Earnings Per Share, Diluted Net loss per share - diluted (in dollars per share) Weighted Average Number of Shares Outstanding, Basic Weighted-average common stock outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Diluted Weighted-average common stock outstanding - diluted (in shares) Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Comprehensive loss: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income (loss): OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized (loss) gain on investments Unrealized gain (loss) on investments Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Foreign currency translation adjustment Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Condensed Consolidated Statements of Stockholders' Equity Equity Components [Axis] Equity Component [Domain] Common Stock [Member] Common Stock Additional Paid-in Capital [Member] Additional Paid-in Capital AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income (Loss) Retained Earnings [Member] Accumulated Deficit Sale of Stock [Axis] Sale of Stock [Domain] Represents information pertaining to at the market offering. At The Market Offering [Member] ATM Program Represents information pertaining to equity offering. Equity Offering [Member] Equity Offering Increase (Decrease) in Stockholders' Equity [Roll Forward] Changes in Stockholders' Equity (Deficit) Shares, Outstanding Balance at end (in shares) Balance at beginning (in shares) Stock Issued During Period, Value, Stock Options Exercised Exercises of common stock options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised (in shares) Exercises of common stock options (in shares) Stock Issued During Period, Value, New Issues Issuance of common stock Stock Issued During Period, Shares, New Issues Issuance of common stock (in shares) Number of common stock issued APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense Stock Issued During Period, Value, Employee Stock Purchase Plan Purchases of common stock under the Employee Stock Purchase Plan Stock Issued During Period, Shares, Employee Stock Purchase Plans Shares issued under ESPP Purchases of common stock under the Employee Stock Purchase Plan (in shares) Condensed Consolidated Statements of Cash Flows Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation Depreciation expense Gain (Loss) on Disposition of Property Plant Equipment Loss on disposal of property and equipment Amortization of Debt Discount (Premium) Net amortization of premiums and accretion of discounts on investments Amount of noncash interest expense on royalty obligation. Noncash Interest Expense On Royalty Obligation Non-cash interest expense on royalty obligation Interest expense related to royalty obligation Amount of noncash interest expense on debt. Noncash Interest Expense On Debt Non-cash interest expense on senior secured term loan Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Amount of non-cash lease expense. Non-cash lease expense Non-cash lease expense Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses Increase (Decrease) in Operating Lease Liability Operating lease liabilities Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Investments Purchases of investments Proceeds from Sale, Maturity and Collection of Investments Proceeds from sales and maturities of investments Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Payments of Stock Issuance Costs Payments of other offering costs for the ATM offering Commission costs Payments of Debt Issuance Costs Payments of debt issuance costs Payments of debt issuance costs Proceeds from Stock Options Exercised Proceeds from exercise of stock options Proceeds from Stock Plans Proceeds from issuance of common stock under employee stock purchase plan Proceeds from Issuance of Common Stock Proceeds from issuance of common stock Proceeds from Issuance of Common Stock Proceeds from Issuance of Secured Debt Proceeds from senior secured term loan, net of discount Proceeds from Convertible Debt Proceeds from the issuance of convertible senior notes, net of commissions Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Effect of exchange rate changes on cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Supplemental Cash Flow Information [Abstract] Supplemental disclosure of non-cash investing and financing activities: Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Right-of-use assets obtained under operating lease arrangements The amount of deferred offering and debt issuance costs included in accounts payable and accrued expenses. Deferred Offering Costs And Debt Issuance Costs Included In Accounts Payable and Accrued Expenses Deferred offering costs and debt issuance costs in accounts payable and accrued expenses Nature of Business Nature of Operations [Text Block] Nature of Business Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Other Non-Current Assets Other Assets Disclosure [Text Block] Other Non-Current Assets Accrued Expenses Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued Expenses Long - Term Obligations Long-Term Debt [Text Block] Long - Term Obligations N/a. License and Collaboration Revenue Collaborative Arrangement Disclosure [Text Block] License and Collaboration Revenue No definition available. License Agreements The entire disclosure for license agreements. License Agreements [Text Block] License Agreements No definition available. Royalty Obligation Debt Disclosure [Text Block] Royalty Obligation Common Stock Equity [Text Block] Common Stock Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Stock-Based Compensation Net Loss Per Share Earnings Per Share [Text Block] Net Loss Per Share Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Related Party Transactions Related Party Transactions Disclosure [Text Block] Related Party Transactions Segment Information Segment Reporting Disclosure [Text Block] Segment Information Subsequent Events Subsequent Events [Text Block] Subsequent Events Disclosure of accounting policy for basis of presentation and consolidation. Basis Of Presentation And Consolidation [Policy Text Block] Basis of Presentation and Consolidation Disclosure of accounting policy for unaudited interim financial information. Unaudited Interim Financial Information, Policy [Policy Text Block] Unaudited Interim Financial Information Use of Estimates, Policy [Policy Text Block] Use of Estimates Derivatives, Embedded Derivatives [Policy Text Block] Embedded Derivative Financial Instruments Disclosure of accounting policy for convertible debt. Convertible Debt, Policy [Policy Text Block] Convertible Instruments Debt, Policy [Policy Text Block] Debt and Debt Issuance Costs New Accounting Pronouncements, Policy [Policy Text Block] Recently Adopted Accounting Standards and Recent Accounting Pronouncements