v3.26.1
COLLABORATIONS, LICENSES AND REVENUE (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 30, 2026
USD ($)
Mar. 31, 2026
USD ($)
Mar. 31, 2026
EUR (€)
Mar. 31, 2025
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2025
USD ($)
COLLABORATIONS, LICENSES AND REVENUE            
Deferred revenue, current   $ 12,000,000       $ 12,000,000
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States            
COLLABORATIONS, LICENSES AND REVENUE            
Deferred revenue liability   0       0
Revenue   0   $ 0    
Accounts receivable   0       0
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan            
COLLABORATIONS, LICENSES AND REVENUE            
Potential milestone payments         $ 89,000,000  
Upfront payment         $ 12,000,000  
Deferred revenue liability   12,000,000        
Deferred revenue, current   12,000,000        
Japan Distribution Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Deferred revenue liability   12,000,000       12,000,000
Upfront for performance obligation   $ 0       $ 0
JHU License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Threshold period to cure breach   30 days 30 days      
Notice period   60 days 60 days      
JHU License Agreement | Subsequent events            
COLLABORATIONS, LICENSES AND REVENUE            
Milestone payments accrued $ 500,000          
CSMC License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Notice period   90 days 90 days      
Exosomes License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Notice period   90 days 90 days      
Minimum | Rome License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Minimum annual royalty payments | €     € 20,000      
Minimum | JHU License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Potential milestone payments   $ 1,850,000        
Obtention of FDA Approval | JHU License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Milestone payments to be made upon completion of certain phases   $ 1,000,000        
Patent rights | JHU License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Agreement effective period   20 years 20 years      
Non Payment of Royalties | CSMC License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Agreement termination period   30 days 30 days      
Non Payment of Royalties | Exosomes License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Threshold period to cure breach   30 days 30 days      
CSMC Agreement Compliance | CSMC License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Agreement termination period   90 days 90 days      
CSMC Agreement Compliance | Exosomes License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Threshold period to cure breach   90 days 90 days      
Material Breach Has Not Been Cured | CSMC License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Agreement termination period   90 days 90 days      
Material Breach Has Not Been Cured | Exosomes License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Threshold period to cure breach   90 days 90 days      
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Agreement termination period   90 days 90 days      
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement            
COLLABORATIONS, LICENSES AND REVENUE            
Threshold period to cure breach   90 days 90 days