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Measurement Input, Premium Measurement Input, Premium [Member] Measurement Input, Premium Total current liabilities Liabilities, Current Positions eliminated (as a percent) Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Collaboration agreement term Collaboration Agreement, Term Collaboration Agreement, Term Individual: Individual [Axis] Collaboration and license revenue Collaboration And License Revenue [Member] Collaboration And License Revenue Sale of common stock, premium on stock price (as a percent) Sale Of Stock, Premium On Stock Price, Percentage Sale Of Stock, Premium On Stock Price, Percentage Other current assets Other Assets, Current Research and development Research and Development Expense [Member] Investment in joint venture Investments in and Advance to Affiliates, Subsidiaries, Associates, and Joint Ventures Net cash provided by investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Document Fiscal Year Focus Document Fiscal Year Focus Schedule of License and Collaboration Agreements [Line Items] Schedule of License and Collaboration Agreements [Line Items] Schedule of License and Collaboration Agreements Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Compensation and related expenses Accrued Employee Benefits, Current Entity Interactive Data Current Entity Interactive Data Current Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] Percentage of common stock beneficially owned not exceed (as a percent) Percentage of Common Stock Beneficially Owned Not Exceed Percentage of common stock beneficially owned not exceed. 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