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Issuance of common stock upon vesting and exercise of stock options, Shares Stock Issued During Period Shares Stock Options Vested And Exercised Property, Plant and Equipment [Abstract] Other assets Other Assets, Noncurrent, Total Other Assets, Noncurrent 2024 Warrants Two Zero Two Four Warrants Member Two Zero Two Four Warrants. Stock Issued During Period Shares Vesting of Restricted Stock Units Net of Shares Withheld for Taxes Exercise of Stock Options and Issuance of Common Stock Under Employee Stock Purchase Plan Stock issued during period shares vesting of restricted stock units net of shares withheld for taxes exercise of stock options and issuance of common stock under employee stock purchase plan. Issuance of common stock upon vesting of RSUs, net of shares withheld for taxes, exercise of stock options, and issuance of common stock under ESPP, Shares Antidilutive Securities Antidilutive Securities [Axis] AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income (Loss) Furniture, fixtures and other. Furniture, Fixtures and Other Furniture, Fixtures and Other [Member] Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued Preferred stock, $0.0001 par value; 10,000,000 shares authorized as of March 31, 2026 and December 31, 2025; 0 shares issued and outstanding as of March 31, 2026 and December 31, 2025 Weighted average grant date fair value of restricted stock, granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Financial Instrument Financial Instrument [Axis] 2025 Warrants Two Zero Two Five Warrants Member 2025 Warrants. 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Restructuring and Related Activities Disclosure [Text Block] Restructuring Plan Related Party Transactions [Abstract] Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Summary of Amortized Cost and Estimated Fair Value of Marketable Securities by Contractual Maturity Maturing after One Year through Five Years Maturing After One Year Through Five Years [Member] Maturing after one year through five years. General and Administrative General and Administrative Expense [Member] General and Administrative Expense Total lease liabilities Operating Lease, Liability Reverse stock split description Stockholders' Equity, Reverse Stock Split US Treasury Bill Securities [Member] U.S. Treasury Bill Lessee Lease Description [Table] Lessee, Lease, Description [Table] Liabilities, Noncurrent [Abstract] Non-current liabilities: Schedule of Restructuring Reserve by Type of Cost [Table Text Block] Summary of Severance and Benefit Cost with Balance of Liability Capital Expenditures Incurred but Not yet Paid Purchases of property and equipment in accounts payable and accrued liabilities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Lease Contractual Term Lease Contractual Term [Domain] Significant Agreements Significant Agreements [Text Block] Significant Agreements. 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Weighted average purchase price Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Weighted-average price per share Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Plan Name [Domain] Plan Name Increase (Decrease) in Other Operating Assets, Total Other assets Increase (Decrease) in Other Operating Assets Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Credit Facility Credit Facility [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights Vesting rights description 30day Option to Purchase Additional Shares Under November 2025 Offering [Member] 30day option to purchase additional shares under November 2025 offering. 30day Option to Purchase Additional Shares Under November 2025 Offering Related and Nonrelated Parties [Axis] Restricted Cash Equivalents Restricted Cash Equivalents [Member] Restricted cash equivalents. 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Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Employee Severance [Member] Severance and Benefits Costs Former Address [Member] Former Address Depreciation, Total Depreciation expense Depreciation Issuance of common stock upon vesting of RSUs, net of shares withheld for taxes, and exercise of stock options Stock Issued During Period Value Stock Options Vested of Restricted Stock Units and Exercised Stock issued during period value stock options vested of restricted stock units and exercised Issuance of common stock upon vesting of RSUs, net of shares withheld for taxes, and exercise of stock options Unrecognized compensation expense related to related to restricted stock units Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Common Stock, Shares, Outstanding Common stock, shares outstanding Beginning Balance, Shares Ending Balance, Shares Restricted cash equivalents Restricted Cash Equivalent, Noncurrent Restricted cash Operating lease liabilities Operating lease liabilities, current Operating Lease, Liability, Current Document Transition Report Document Transition Report Operating Expenses Total operating expenses Research and Development Expense, Total Research and development Research and Development Expense Research and development expense Leases Lessee, Operating Leases [Text Block] Statement of Cash Flows [Abstract] Stock Issued During Period Value Private Placement, Net of Issuance Costs Stock issued during period value private placement, net of issuance costs. Issuance of common stock from private placement, net of issuance costs Equity [Text Block] Stockholders' Equity and Warrants Earnings Per Share [Text Block] Net Loss Per Share Net loss Net loss Other Nonoperating Income Other income Operating lease cost Operating Lease, Cost Warrants and Rights Outstanding, Term Warrants expiration period Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Summary of Amounts Reported in Condensed Consolidated Balance Sheets and Weighted-average Lease Term and Discount rate Information Schedule of operating lease assets and liabilities, weighted average lease term and discount rate. Schedule of Operating Lease Assets and Liabilities, Weighted Average Lease Term and Discount Rate [Table Text Block] Issuance costs related to private placement included in accounts payable and accrued expenses Issuance costs related to private placement included in accounts payable and accrued expenses. Issuance costs related to private placement included in accounts payable and accrued expenses Operating cash flows for operating leases Operating Lease, Payments Assets Assets [Abstract] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Rule 10b5-1 Trading Arrangement Plan [Member] Rule 10b5-1 Trading Arrangement Plan. Restructuring and Related Activities [Abstract] Document Fiscal Year Focus Document Fiscal Year Focus RemeGen Warrant [Member] RemeGen Warrant. RemeGen Warrant Credit losses related to marketable securities Debt Securities Available For Sale Change In Present Values Expense Reversal Debt securities available for sale change in present values expense reversal Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Cash flows from investing activities Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Underwritten Public Offering [Member] Underwritten public offering. Underwritten Public Offering Research and Development Research and Development Expense [Member] Research and Development Expense Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Restructuring Cost and Reserve [Line Items] Schedule of Fair Value and Gross Unrealized Losses of Marketable Securities Unrealized Gain (Loss) on Investments [Table Text Block] Fair Value Disclosures [Abstract] Regulatory Milestone Payments Related To Agreement Regulatory milestone payments related to agreement. Regulatory milestone payments related to agreement Share-Based Payment Arrangement [Abstract] Assets, Fair Value Disclosure, Total Assets, Fair Value Disclosure Assets Sale of Stock Sale of Stock [Axis] Lessee, Operating Sublease, Existence of Option to Extend [true false] Operating sublease, option to extend Lessee, Operating Sublease, Option to Extend Lessee operating option to extend Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash used in investing activities Private Placement [Member] Private Placement Fair value assets, transfers into level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3 Title of 12(b) Security Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Money Market Funds Money Market Funds [Member] Related and Nonrelated Parties [Domain] Unrealized (loss) Gain on Available-for-Sale Securities Unrealized (loss) gain on available-for-sale securities. Unrealized (loss) gain on available-for-sale securities Document Information [Table] Stock Issued During Period Value, Private Placement Stock issued during period value, private placement. Issuance costs for private placement Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Salaries and Benefits [Member] Salaries and benefits. Salaries and Benefits Schedule of Property and Equipment, Net Property, Plant and Equipment [Table Text Block] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Additional Paid-In Capital Additional Paid-in Capital [Member] Measurement Frequency [Domain] Measurement Frequency Income Statement Location Statement of Income Location, Balance [Axis] Trading Symbol Trading Symbol Property and Equipment, Net Property, Plant and Equipment Disclosure [Text Block] Related Party Transaction [Table] Series A-1 Redeemable Convertible Preferred Stock Series A One Redeemable Convertible Preferred Stock [Member] Series A - one redeemable convertible preferred stock. Subsequent Event Type [Axis] Employee-related Liabilities, Current, Total Employee-related Liabilities, Current Employee-related expenses, including Restructuring Liability (Note 12) Liabilities Operating Lease, Liability [Abstract] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Cash flows from financing activities Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Fair Value, Recurring Fair Value, Recurring [Member] Entity Ex Transition Period Entity Ex Transition Period Restructuring plan, loss on disposal Restructuring plan, loss on disposal Liabilities [Member] Liabilities. Liabilities Other than Temporary Impairment, Credit Losses Recognized in Earnings, Categories of Investments Other than Temporary Impairment, Credit Losses Recognized in Earnings, Categories of Investments [Domain] Equity Components Equity Components [Axis] RemeGen Warrants [Member] RemeGen Warrants. RemeGen Warrant Nonoperating Income (Expense) Total other (expense) income Equity Component Equity Component [Domain] Asset Class Asset Class [Axis] Address Type [Domain] Shares of common stock issued under ESPP Stock Issued During Period, Shares, Employee Stock Purchase Plans Contractual term Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Entity Addresses, Address Type [Axis] Liabilities Liabilities, Fair Value Disclosure Liabilities, Fair Value Disclosure, Total One-time Termination Benefits [Member] One-time termination benefits Prepaid Expense, Current, Total Prepaid expenses Prepaid Expense, Current Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Common stock, $0.0001 par value; 800,000,000 and 400,000,000 shares authorized as of March 31, 2026 and December 31, 2025, respectively; 54,185,582and 38,720,196 shares issued and outstanding as of March 31, 2025 and December 31, 2025, respectively Warrants And Rights Issued Warrants and rights issued. Amount of warrant issued Warrants and Rights Outstanding Warrants outstanding Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Preferred stock, shares authorized Preferred Stock, Shares Authorized Corporate bonds Corporate Bonds [Member] Corporate bonds member. Repurchases of shares for tax withholdings upon vesting of restricted stock unit awards Payment, Tax Withholding, Share-Based Payment Arrangement Total Unrealized loss Total Unrealized loss Total Unrealized loss Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Total Unrealized loss Debt Security Category Debt Security Category [Axis] Related Party Transaction [Line Items] Employee Stock [Member] Employee Stock Purchase Plan Entity Registrant Name Entity Registrant Name Gross Unrealized Holding losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Subsequent Events [Abstract] Measurement Frequency Measurement Frequency [Axis] Summary of Right-of-Use Assets and Lease Liabilities Summary Of Right Of Use Assets And Lease Liabilities Table [Text Block] Summary of right-of-use assets and lease liabilities . Proceeds from the issuance of common stock from at-the-market sales agreement, net of issuance costs Aggregate net proceeds Net proceeds after deducting offering expenses Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive (loss) income Cash payments Payments for Restructuring Cash payments Payments to Acquire Property, Plant, and Equipment, Total Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Restricted stock units granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Total assets Assets Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Income Statement [Abstract] Restructuring Cost [Table] Trem-cel [Member] Trem-cel. Trem-cel Fair value assets, level 2 to level 1 transfers amount Fair value assets level2 to level1 transferred amount. Fair Value Assets Level2 to Level1 Transferred Amount Stock Issued During Period, Shares, New Issues Common stock shares sold Denominator, diluted Earnings Per Share, Diluted [Abstract] Net loss per share attributable to common stockholders, diluted Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Summary of the Segment Profit or Loss, Including Significant Segment Expenses Schedule of Segment Reporting Information, by Segment [Table Text Block] City Area Code City Area Code Schedule of other lease activity. Schedule of Other Lease Activity [Table Text Block] Summary of Other Lease Activity Variable lease cost Variable Lease, Cost Transaction costs related to license agreement Transaction Costs Related to License Agreement Transaction costs related to license agreement. Weighted-average remaining lease term (years) Operating Lease, Weighted Average Remaining Lease Term Segment Reporting Information [Line Items] Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split conversion ratio Lease Expiration Date Lease expiration date Total lease cost Lease, Cost Manufacturing expenses Manufacturing Expenses, Current Manufacturing expenses, current. Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property and equipment, net Property and equipment, net Property, Plant and Equipment, Net Stock Issued During Period Value Issuance Of Common Stock From Exercise of Warrants Stock issued during period value issuance of common stock from exercise of warrants. Issuance of common stock from exercise of pre-funded warrants Total cash, cash equivalents and restricted cash equivalents as shown on the statements of cash flows Cash, cash equivalents and restricted cash equivalents, beginning of period Cash, cash equivalents and restricted cash equivalents, end of period Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Corporate Bond Securities [Member] Corporate Bonds Loss from operations Loss from operations Operating Income (Loss) Accumulated Deficit Retained Earnings [Member] Yankee Bonds[Member] Yankee bonds Yankee bonds Yankee Bonds Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Share-based Payment Arrangement, Noncash Expense, Total September 2025 Reverse Stock Split Reverse Stock Split Policy Text Block Reverse stock split. Payments of Stock Issuance Costs Cash payment related to warrant issued Payment of issuance costs related to private placement Restructuring and Related Cost, Number of Positions Eliminated Reduction of workforce, number of full time employees Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Less than twelve months, Fair value Interest amortization on marketable securities. Interest Amortization On Marketable Securities Interest amortization on marketable securities Stock Issued During Period Shares Private Placement Stock issued during period shares private placement. Issuance costs for private placement, shares Operating Lease, Weighted Average Discount Rate, Percent Weighted-average discount rate Operating lease liabilities, non-current Operating Lease, Liability, Noncurrent Operating lease liabilities, less current portion Level 1 Fair Value, Inputs, Level 1 [Member] Class Of Stock [Line Items] Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by (used in) financing activities Summary of Lease Expense Lease, Cost [Table Text Block] Investments [Member] Marketable Securities Issuance of common stock upon vesting and exercise of stock options Stock Issued During Period Value Stock Options Vested And Exercised Stock issued during period value stock options vested and exercised. Potential Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Debt Securities Available For Sale [Table] Debt Securities, Available-for-Sale [Table] Entity Interactive Data Current Entity Interactive Data Current Income Statement Location Statement of Income Location, Balance [Domain] Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Series A-2 Series A-2 Redeemable Convertible Preferred Stock Series A Two Redeemable Convertible Preferred Stock [Member] Series A - two redeemable convertible preferred stock. Expected Proceeds From Issuance Of Common Stock Expected proceeds from issuance of common stock. Additional expected net proceeds Segment Reporting, Expense Information Used by CODM, Type [Extensible Enumeration] Segment Expenses Income Segment expenses income. Segment expenses Entity Tax Identification Number Entity Tax Identification Number Stock-based Compensation Stock Based Compensation [Member] Stock Based Compensation. VCAR33 [Member] VCAR33. VCAR33 Increase in annual fixed rental payments Increase In Annual Fixed Rental Payments Increase in annual fixed rental payments. Local Phone Number Local Phone Number Unrecognized compensation expense related to stock options Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Restructuring Reserve Accelerated Amortization of Right-of-use Assets Restructuring Reserve Accelerated Amortization of Right-of-use Assets Restructuring reserve accelerated amortization of right-of-use assets Accounting Policies [Abstract] Numerator: Net Income (Loss) Attributable to Parent [Abstract] Class of Stock [Domain] Class of Stock Stock Issued During Period Shares Private Placement, Net of Issuance Costs Stock issued during period shares private placement, net of issuance costs. Issuance of common stock from private placement, net of issuance costs, shares Number of shares available for future issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Number of additional shares to be purchased Unrecognized share based compensation expense, recognition period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Accrued Professional Fees, Current Professional fees Cash and marketable securities Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-Term Investments, Total Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Loss on Disposal of Long-lived Assets [Member] Loss on Disposal of Long-lived Assets. Loss on Disposal of Long-lived Assets Entity Emerging Growth Company Entity Emerging Growth Company General Corporate Activities [Member] General corporate activities. General Corporate Activities