v3.26.1
License Agreements - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Jan. 31, 2025
Feb. 28, 2025
Nov. 30, 2024
Mar. 31, 2026
Mar. 31, 2025
Dec. 31, 2025
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Research and development       $ 7,575 $ 10,837  
Accrued expenses and other current liabilities       8,101   $ 9,143
Allievex Purchase Agreement            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Consideration paid     $ 5,000      
Consideration assumed as certain liabilities       7,800    
Estimated receivable       2,600    
Sales milestones       100,000    
Allievex Purchase Agreement | Maximum | MPSIIIB            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Development and regulatory milestones       25,500    
HBM Alpha Therapeutics, Inc            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Upfront payments   $ 5,000        
Development and regulatory milestones       390,000    
Payments to acquire in process research and development       5,000    
Fair value of pre-funded warrants issued       700    
Percentage of issued pre-funded warrants 4.99%          
Pre-funded warrants, expiration period Dec. 31, 2025          
BioMarin [Member]            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Obligations to pay third party       $ 0