v3.26.1
Segment Reporting - Schedule of Functional Operating Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Research and Development Expenses    
Research and development expenses $ 13,004 $ 25,378
General and Administrative Expenses    
General and administrative expenses 5,938 5,943
Loss from operations (18,942) (31,321)
Other income (expense):    
Interest income 1,250 1,122
Other (expense) income, net (56) (3)
Total other income, net 1,194 1,119
Income tax expense (15) 0
Net loss (17,763) (30,202)
Direct Research and Development Expenses | PGN-EDODM1    
Research and Development Expenses    
Research and development expenses 5,995 11,708
Direct Research and Development Expenses | PGN-EDO51    
Research and Development Expenses    
Research and development expenses 20 3,416
Platform and External    
Research and Development Expenses    
Research and development expenses 86 370
Personnel-related (Including Stock-based Compensation)    
Research and Development Expenses    
Research and development expenses 5,115 7,471
General and Administrative Expenses    
General and administrative expenses 3,457 3,595
Facility Related and Other    
Research and Development Expenses    
Research and development expenses 1,210 1,264
General and Administrative Expenses    
General and administrative expenses 514 457
Other Research and Development Expenses    
Research and Development Expenses    
Research and development expenses 578 1,149
Other General and Administrative    
General and Administrative Expenses    
General and administrative expenses $ 1,967 $ 1,891