75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Consolidated Balance Sheets
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75020 - Statement - Condensed Consolidated Balance Sheets (Parenthetical)
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75030 - Statement - Condensed Consolidated Statements of Operations
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75040 - Statement - Condensed Consolidated Statements of Comprehensive Loss
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75050 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity
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75060 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity (Parenthetical)
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75070 - Statement - Condensed Consolidated Statements of Cash Flows
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75080 - Statement - Condensed Consolidated Statements of Cash Flows (Parenthetical)
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995455 - Disclosure - Nature of the Business and Basis of Presentation
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995465 - Disclosure - FA212 Asset Acquisition
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995475 - Disclosure - Outlicensing Agreements
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995485 - Disclosure - Acquisition
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995495 - Disclosure - Fair Value Measurements
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995505 - Disclosure - Available-for-Sale Securities
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995515 - Disclosure - Property and Equipment, Net
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995525 - Disclosure - Prepaid Expenses and Other Current Assets
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995535 - Disclosure - Accrued Expenses and Other Current Liabilities
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995545 - Disclosure - Stockholders' Equity
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995555 - Disclosure - Equity-Based Compensation
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995565 - Disclosure - Income Taxes
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995575 - Disclosure - Leases
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995585 - Disclosure - Commitments and Contingencies
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995595 - Disclosure - Net Loss Per Share
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995605 - Disclosure - Segment Reporting
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995615 - Disclosure - Subsequent Events
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995625 - Disclosure - Nature of the Business and Basis of Presentation (Policies)
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995635 - Disclosure - Collaborations (Tables)
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995645 - Disclosure - Acquisition (Tables)
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995655 - Disclosure - Fair Value Measurements (Tables)
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995665 - Disclosure - Available-for-Sale Securities (Tables)
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995675 - Disclosure - Property and Equipment, Net (Tables)
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995685 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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link:calculationLink
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995695 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995705 - Disclosure - Equity-Based Compensation (Tables)
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995715 - Disclosure - Net Loss Per Share (Tables)
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995725 - Disclosure - Segment Reporting (Tables)
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995735 - Disclosure - Restructuring (Tables)
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995745 - Disclosure - Nature of the Business and Basis of Presentation - Additional Information (Detail)
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995755 - Disclosure - FA212 Asset Acquisition - Additional Information (Detail)
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995765 - Disclosure - Outlicensing Agreements - Additional Information (Detail)
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995775 - Disclosure - Acquisition - Additional Information (Detail)
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995785 - Disclosure - Acquisition - Summary of Fair Values of Assets Acquired and Liabilities Assumed (Detail)
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995795 - Disclosure - Fair Value Measurements - Summary of Financial Assets and Liabilities that are Measured at Fair Value on a Recurring Basis (Detail)
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995805 - Disclosure - Fair Value Measurements - Summary of Significant Unobservable Inputs Used in Valuing Developmental Milestone Derivative Liabilities (Detail)
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995815 - Disclosure - Fair Value Measurements - Summary of Fair Value of Derivative Liabilities (Details)
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995825 - Disclosure - Fair Value Measurements - Additional Information (Detail)
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995835 - Disclosure - Available-for-Sale Securities - Schedule of Available-for-Sale Securities (Detail)
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995845 - Disclosure - Available-for-Sale Securities - Additional Information (Detail)
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995855 - Disclosure - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Detail)
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995865 - Disclosure - Accrued Expenses and Other Current Liabilities - Summary of Accrued Expenses and Other Current Liabilities (Detail)
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995875 - Disclosure - Stockholders' Equity - Additional Information (Detail)
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995885 - Disclosure - Equity-Based Compensation - Schedule of Equity-based Compensation Expense (Detail)
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995895 - Disclosure - Equity-Based Compensation - Additional Information (Detail)
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995905 - Disclosure - Equity Based Compensation - Summary Of Stock Option Activity (Detail)
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995915 - Disclosure - Equity-Based Compensation - Summary of Assumptions Used in Black-Scholes Option-Pricing Model for Stock Options Granted (Detail)
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995925 - Disclosure - Equity-Based Compensation - Summary of Restricted Stock Unit Activity (Detail)
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995935 - Disclosure - Equity-Based Compensation - Summary of Performance Stock Units Activity (Details)
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995945 - Disclosure - Income Taxes - Additional Information (Detail)
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995955 - Disclosure - Leases - Additional Information (Detail)
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995965 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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995975 - Disclosure - Net Loss Per Share - Schedule Computation of Basic and Diluted Net Loss (Detail)
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995985 - Disclosure - Net Loss Per Share - Additional Information (Detail)
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995995 - Disclosure - Net Loss Per Share - Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share (Detail)
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996005 - Disclosure - Segment Reporting - Additional Information (Detail)
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996015 - Disclosure - Segment Reporting - Schedule of Segment Expenses, Other Segment Items, and Segment Net Loss (Detail)
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996025 - Disclosure - Restructuring - Addition Information (Detail)
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996035 - Disclosure - Restructuring - Schedule of Accrued Restructuring Charges (Detail)
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Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Acquisition related costs
Business Combination, Acquisition-Related Cost, Expense
Research and development expense, other
Other Research and Development Expense
Stock units outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Beginning Balance
Vesting of restricted and performance stock, units
Vesting of Restricted and Performance Stock Units
Vesting of restricted and performance stock units.
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Preferred stock, shares issued
Balance Sheet Location
Statement of Financial Position Location, Balance [Domain]
Maugeri license agreement member.
Maugeri License Agreement [Member]
Maugeri License Agreement [Member]
Change in Fair Value Of Derivative Liabilities
Change in fair value of derivative liabilities.
Change in fair value of derivative liabilities
Change in fair value of derivative liabilities
Change in fair value of derivative liabilities
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing, financing and operating activities:
Plan Name [Axis]
Plan Name
Prepaid other and other current assets
Prepaid Other and Other Current Assets
Prepaid other and other current assets.
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Amendment and restatement of ESPP member.
Amendment and Restatement of ESPP [Member]
Amendment and Restatement of ESPP [Member]
Operating Expenses [Abstract]
Operating expenses:
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Product and Service [Axis]
Fair value, assets, transfers into level 1, amount
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In To Level 1
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In To Level 1.
Amended and Restated 2020 Plan [Member]
Amended and Restated Two Thousand And Twenty Incentive Plan [Member]
Amended and restated two thousand and twenty incentive plan.
Document Fiscal Period Focus
Document Fiscal Period Focus
Entity Shell Company
Entity Shell Company
Segment Reporting, Policy [Policy Text Block]
Segment Data
Cash and Cash Equivalent
Cash and cash equivalents
Cash and cash equivalents as presented on balance sheet
Cash and Cash Equivalents, at Carrying Value, Total
Restructuring charges expected to be paid
Restructuring charges expected to be paid
Restructuring charges expected to be paid.
Common Stock, Shares, Issued
Common stock, shares issued
Statement [Table]
Statement [Table]
Prepaid expenses and other current assets.
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid Expenses and Other Current Assets
Restricted cash, non-current, as presented on balance sheet
Restricted cash, as presented on balance sheet
Restricted cash, non-current
Restricted cash, net of current portion
FA212 LLC [Member]
FA212 LLC.
FA212 LLC [Member]
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of-use assets acquired through operating leases
Sale [Member]
Sale.
Sale [Member]
Ultragenyx
Ultragenyx [Member]
Ultragenyx [Member]
Weighted average grant date fair value of stock options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Cash payment
Payments to Acquire Businesses, Gross
Transaction costs
Asset Acquisition Transaction Costs
Asset acquisition transaction costs.
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Expired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Warrants [Member]
Warrant [Member]
Entity Filer Category
Entity Filer Category
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Liabilities and Equity
Total liabilities and stockholders’ equity
Total current liabilities
Business Combination, Recognized Liability Assumed, Liability, Current
Payables and Accruals [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable at March 31, 2026
Restructuring Type [Axis]
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Severance Costs
Restructuring charges related to severance payment and other employee-related costs
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Summary of Fair Value of Derivative Liabilities
Shares Issued, Price Per Share
Common stock issued price per share
Adjustments to additional paid in capital, pre-funded warrants issued, issuance costs.
Adjustments to Additional Paid in Capital, Pre-funded Warrants Issued, Issuance Costs
Pre-funded warrants issuance costs
Other Noncash Income (Expense)
Other Noncash Income (Expense), Total
Other
Options to Purchase Common Stock [Member]
Investment Income, Interest
Interest income
Derivative Liabilities, Unobservable Input
Derivative Liability, Measurement Input
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of underwriting discounts and commissions
Proceeds From Issuance Of Common Stock And PreFunded Warrants In Public Offering, Net Of Underwriting Discounts And Commissions
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of underwriting discounts and commissions.
Non-current assets:
Assets, Noncurrent [Abstract]
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block]
Schedule of Segment Expenses, Other Segment Items, and Segment Net Loss
Additional Paid in Capital, Common Stock
Additional paid-in capital
Related Party [Member]
Related Party [Member]
Fair value, liabilities, transfers out of level 1, amount
Fair value measurement with unobservable inputs reconciliation recurring basis liability transfers out of level 1.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Transfers Out Of Level 1
Accrued expenses and other current liabilities.
Accrued Expenses And Other Current Liabilities Table [Text Block]
Summary of Accrued Expenses and Other Current Liabilities
Vesting [Domain]
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Common stock purchased
Schedule of Computation of Basic and Diluted Net Loss per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Investments Classified by Contractual Maturity Date [Table Text Block]
Summary Estimated Fair Value and Amortized Cost of Available-for-Sale Securities by Contractual Maturity
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Stock options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Outstanding at January 1, 2026
Outstanding at March 31, 2026
Total current assets
Business Combination, Recognized Asset Acquired, Asset, Current
Liabilities, Current
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Significant Unobservable Inputs Used in Valuing Developmental Milestone Derivative Liabilities
Consolidation Items [Domain]
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Number of headcount reduced, percentage
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Entity Small Business
Entity Small Business
Available For Sale Securities Weighted Average Maturity period
Available For Sale Securities Weighted Average Maturity Period
Available-for-sale securities weighted average contractual maturity period
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Fair value asset level 1 to level 2 transfers amount.
Fair Value Asset Level 1 To Level 2 Transfers Amount
Fair value, assets, level 1 to level 2 transfers, amount
Forfeitures
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Net proceeds from offering
Proceeds from Issuance Initial Public Offering
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Liabilities Accrued expenses
Accrued expenses
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Liabilities Accrued expenses
Share-Based Payment Arrangement [Text Block]
Equity-Based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Lease Contractual Term [Axis]
Leases [Abstract]
Adjustments to additional paid in capital, net of sales commissions.
Adjustments to Additional Paid in Capital, Net Of Sales Commissions
Sales commissions
Contract with Customer, Liability
Deferred revenue, Ending balance
Deferred revenue, Beginning balance
Deferred revenue - related party
Contract with Customer, Liability, Total
Amendment Flag
Amendment Flag
Product and Service [Domain]
Liabilities and Equity [Abstract]
Liabilities and Stockholders’ Equity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Change in operating lease liability
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Segment reporting, CODM, profit (loss) measure, how used, description
Common Stock [Member]
Common Stock [Member]
Common Stock [Member]
Fair value, assets, transfers into level 2, amount
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In to Level 2
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In to Level 2
Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Debt Securities, Available-for-Sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers out of Level 3
Fair value, assets, transfers out of level 3, amount
Summary of Assumptions Used in Black-Scholes Option-Pricing Model for Stock Options Granted
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Fair Value Hierarchy and NAV [Axis]
Level 3 [Member]
Earnings Per Share [Abstract]
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Vesting of Restricted and Performance Stock Units Value
Vesting of restricted and performance stock units value.
Vesting of restricted and performance stock units
Statement of Financial Position Location, Balance [Axis]
Balance Sheet Location
Right of use asset
Operating Lease, Right-of-Use Asset
Operating lease, right-of-use assets
Maximum percentage of royalty or sublicense income payments of world-wide licensed product sales
Maximum percentage of royalty or sublicense income payments of world-wide licensed product sales.
Payments to Acquire Debt Securities, Available-for-Sale
Purchases of available-for-sale securities
Operating lease, right-of-use asset
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Operating lease, right-of-use asset
Business combination, Recognized identifiable assets acquired and liabilities assumed, Operating lease, Right-of-use asset.
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Debt Securities, Available-for-Sale [Table Text Block]
Schedule of Available-for-Sale Securities
Asset Acquisition [Table]
Investments, Debt and Equity Securities [Abstract]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase in cash, cash equivalents, and restricted cash
Subsequent Event Type [Domain]
Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Common stock equivalents excluded from calculation of diluted net loss per share
Number of share reserved for future issuance
Deferred Compensation Arrangement with Individual, Common Stock Reserved for Future Issuance
Asset acquisition, assumed cumulative sales milestone payments.
Asset Acquisition, Assumed Cumulative Sales Milestone Payments
Assumed cumulative sales milestone payments
Common Stock, Par or Stated Value Per Share
Common stock, par value
Accrued restructuring costs.
Accrued restructuring charges, ending balance
Accrued restructuring charges, beginning balance
Accrued restructuring costs
Share-Based Payment Arrangement, Tranche One [Member]
Tranche One [Member]
Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Expected volatility, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Total available-for-sale securities
Fair Value
Debt Securities, Available-for-Sale
Total available-for-sale securities, fair value
Outlicense Agreements [Member]
Outlicense Agreements.
Exercises of common stock options, units
Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Fair Value Measurements
Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]
Accrued expenses and other current liabilities
Accrued Liabilities, Current
Accrued expenses and other current liabilities
Accrued Liabilities, Current, Total
Accrued compensation.
Accrued Compensation [Member]
Accrued Compensation [Member]
Asset acquisition, assumed contingent development milestone payments.
Asset Acquisition, Assumed Contingent Development Milestone Payments
Assumed contingent development milestone payments
External Research And Development Other [Member]
External research and development other.
External Research and Development Other [Member]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Document Quarterly Report
Document Quarterly Report
Other non-current assets
Business Combination, Recognized Asset Acquired, Other Asset, Noncurrent
Entity Address, State or Province
Entity Address, State or Province
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Nonvested RSUs/PSUs at January 1, 2026
Nonvested RSUs/PSUs at March 31, 2026
Summary of Fair Values of Assets Acquired and Liabilities Assumed
Business Combination [Table Text Block]
Asset Acquisition [Domain]
Total financial liabilities
Financial Liabilities Fair Value Disclosure
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Gross Unrealized Gain
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Equity-based Compensation Expense
Exercises of common stock options
Stock Issued During Period, Value, Stock Options Exercised
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Expenses and Other Current Liabilities
Collaborative Arrangement Disclosure [Text Block]
Outlicensing Agreements
Nonvested Performance Stock Units [Member]
Performance Stock Units [Member]
Performance Shares [Member]
Non-cash lease expense
Non cash Lease Expense
Non-cash lease expense.
Subsequent Event [Member]
Subsequent Event [Member]
Issuance of common stock in private placement for payment of developmental milestone consideration, units
Issuance Of Common Stock In Private Placement For Payment Of Developmental Milestone Consideration
Issuance of common stock in private placement for payment of developmental milestone consideration.
Property, Plant and Equipment [Abstract]
Number of shares of common stock reserved for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Number of additional shares authorized for common stock for equity awards
Other Assets, Noncurrent
Other non-current assets
Fair Value Measurement Inputs and Valuation Techniques [Table]
Debt Securities, Available-for-Sale, Current
Available-for-sale securities
Antidilutive Securities [Axis]
Antidilutive Securities
Prepaid expenses and other current assets
Business Combination, Recognized Asset Acquired, Prepaid Expense and Other Asset, Current
Expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Percentage of vesting
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Vested and expected to vest, Aggregate Intrinsic Value
Fair value, liabilities, transfers out of level 2, amount
Fair value measurement with unobservable inputs reconciliation recurring basis liability transfers out of level 2.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Transfers Out Of Level 2
Vesting of restricted stock units value.
Vesting Of Restricted Stock Units Value
Vesting of restricted stock units
Milestone payments upon achievement of regulatory milestone.
Milestone Payments Upon Achievement Of Regulatory Milestone
Milestone payments upon achievement of regulatory milestone
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income [Member]
Derivative Liability, Total
Derivative liabilities
Derivative liabilities at fair value
Derivative Liabilities, Fair Value
Fair value of derivative liabilities as of January 1, 2025
Fair value of derivative liabilities as of September 30, 2025
Cash and Cash Equivalents [Domain]
Total consideration paid
Total consideration paid
Total purchase price
Cash
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value - 10,000,000 shares authorized at March 31, 2026 and December 31, 2025; no shares issued or outstanding at March 31, 2026 and December 31, 2025
Minimum [Member]
Minimum [Member]
Weighted average grant date fair value
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table]
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Financial liabilities
Liabilities, Fair Value Disclosure [Abstract]
AavantiBio, Inc [Member]
AavantiBio, Inc.
Segment Reporting [Abstract]
Total assets
Business Combination, Recognized Asset Acquired, Asset
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets and Liabilities that are Measured at Fair Value on a Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 1
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 1.
Fair value, assets, transfers out of level 1, amount
Current assets:
Business Combination, Recognized Asset Acquired, Asset, Current [Abstract]
Shares, Outstanding
Ending balance, units
Beginning balance, units
Sublease income
Sublease Income
Gabriel Brooks, M.D [Member]
Gabriel Brooks, M.D.
Gabriel Brooks, M.D [Member]
Commitments and Contingencies
Commitments and contingencies (Note 10)
Leases
Lessee, Leases [Policy Text Block]
One time transaction costs
Business Combination, Separately Recognized Transaction, Acquisition-Related Cost, Incurred
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Nonvested RSUs/PSUs at March 31, 2026
Nonvested RSUs/PSUs at January 1, 2026
Accrued Milestone Payment [Member]
Accrued milestone payment.
Accrued Milestone Payment [Member]
General and Administrative Expense [Member]
General and Administrative [Member]
Forcast [Member]
Forecast [Member]
Issuance of common stock,to a related party, in connectionwith the Stock Purchase Agreement
Issuance Of Common Stock Value To Related Party In Connection With Stock Purchase Agreement
Issuance of common stock value to related party in connection with stock purchase agreement.
Issuance of common stock in connection with employee stock purchase plan
Restricted Cash, Current
Restricted cash, current
Common Stock Issued As Payment For Developmental Milestone Consideration
Common stock issued as payment for developmental milestone consideration.
Common stock issued as payment for developmental milestone consideration
Common stock issued as payment for developmental milestone consideration
Gain (Loss) on Derivative Instruments, Net, Pretax
Gain (Loss) on Derivative Instruments, Net, Pretax, Total
Change in fair value of derivative liabilities
Finance lease liabilities
Finance Lease, Liability, Current
Prepaid research and development expenses, current.
Prepaid Research And Development Expenses Current
Prepaid research and development expenses
Non-current liabilities:
Liabilities, Noncurrent [Abstract]
Schedule of Accrued Restructuring Charges
Schedule of Restructuring Reserve by Type of Cost [Table Text Block]
Capital Expenditures Incurred but Not yet Paid
Property and equipment purchases included in accounts payable and accrued expenses
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net loss
Net loss
Condensed consolidated net loss
Lease Contractual Term [Domain]
Cash and cash equivalents
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Share-Based Payment Arrangement, Recognized Amount [Abstract]
Development milestone payments
Development milestone payments.
Development Milestone Payments
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average shares of common stock outstanding, basic
Weighted average shares of common stock outstanding used to compute basic net loss per share
First development milestone payment in shares
First development milestone payment in shares.
Scenario [Axis]
Payments for (Proceeds from) Available-for-Sale Securities, Short-Term
Proceeds from sales and maturities of available-for-sale securities
Exercisable, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Arkea bio corp.
Arkea Bio Corp [Member]
Arkea Bio Corp [Member]
Net proceeds from private placement
Company received net proceeds
Proceeds from Issuance of Private Placement
Subsequent Events [Text Block]
Subsequent Events
Asset Acquisition, Consideration Transferred, Transaction Cost
Aggregate acquisition cost
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Equity-based compensation expense
Timing of achieving certain development milestones.
Timing Of Achieving Certain Development Milestones [Member]
Timing of Achieving Certain Development Milestones [Member]
Beginning balance
Equity, Attributable to Parent
Ending balance
Total stockholders’ equity
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Statement of Stockholders' Equity [Abstract]
Tranche Two [Member]
Share-Based Payment Arrangement, Tranche Two [Member]
Type of Restructuring [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Property and equipment
Business Combination, Recognized Asset Acquired, Property, Plant, and Equipment
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Property, Plant, and Equipment, Total
Building Interior [Member]
building interior [Member]
Building interior.
Accrued Expenses And Other Current Liabilities [Line Items]
Accrued Expenses And Other Current Liabilities [Line Items]
Accrued Expenses And Other Current Liabilities [Line Items]
Two thousand and twenty four inducement stock incentive plan.
Two Thousand and Twenty Four Inducement Stock Incentive Plan [Member]
2024 Inducement Stock Incentive Plan [Member]
Proceeds from issuance of common stock in at-the-market public offering, net of sales commissions
Proceeds From Issuance Of Common Stock In At The Market Public Offering Net Of Sales Commissions
Proceeds from issuance of common stock in at the market public offering net of sales commissions.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Discount Rate [Member]
Measurement Input, Discount Rate [Member]
Business acquisition, effective date of acquisition
Business Combination, Effective Date of Acquisition
Upfront payment
Asset Acquisition Upfront Payment
Asset Acquisition Upfront Payment
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, Other Segment Item, Amount
Other segment items
Plan Name
Plan Name [Domain]
Cumulative sales milestone payments.
Cumulative Sales Milestone Payments
Cumulative sales milestone payments
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Business Description and Basis of Presentation [Text Block]
Nature of the Business and Basis of Presentation
Description of vesting rights
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights
Certificates of Deposit [Member]
Certificates of Deposit [Member]
Warrants outstanding
Class of Warrant or Right, Outstanding
Issuance of common stock in private placement for payment of developmental milestone consideration
Issuance Of Common Stock Value In Private Placement For Payment Of Developmental Milestone Consideration
Issuance of common stock value in private placement for payment of developmental milestone consideration.
Liabilities and Stockholders' Equity
Business Combination, Recognized Liability Assumed, Liability [Abstract]
Restructuring Plan [Axis]
Related and Nonrelated Parties [Axis]
Asset Acquisition [Text Block]
FA212 Asset Acquisition
Fair Value, Measurement with Unobservable Inputs Reconciliation, Liability, Transfers Into Level 3
Fair value, liabilities, transfers into level 3, amount
Area of subleased agreement
Area of Real Estate Property
Entity Address, City or Town
Entity Address, City or Town
Number of reportable segment
Number of Reportable Segments
Security Exchange Name
Security Exchange Name
Business acquisition, Acquisition completion date
Business Combination, Date of Acquisition Agreement
Counterparty Name [Axis]
Counterparty Name
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest at March 31, 2026
Shares Issued for Milestone Payment
Shares issued for milestone payment.
Shares issued for second milestone payment
Internal General And Administrative Expense [Member]
Internal general and administrative expense.
Internal General and Administrative Expense [Member]
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Asset acquisition
Asset acquisition.
Asset Acquisition [Policy Text Block]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, cash equivalents, and restricted cash at end of period
Cash, cash equivalents, and restricted cash at beginning of period
Total cash, cash equivalents, and restricted cash, as reported in the condensed consolidated statements of cash flows
Cash paid for Interest
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Statistical Measurement [Domain]
Statistical Measurement
Alexander Cumbo [Member]
Alexander Cumbo.
Alexander Cumbo [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Common stock warrants exercise price per share
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Document Period End Date
Document Period End Date
SGT-212 [Member]
SGT-212 member.
SGT-212 [Member]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Exercisable at March 31, 2026
Fair value measurement with unobservable inputs reconciliation recurring basis liability transfers in to level 1.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Transfers In To Level 1
Fair value, liabilities, transfers into level 1, amount
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Member]
Nonvested Restricted Stock Units [Member]
Accrued Expenses Other and Other Current Liabilities [Member]
Accrued espenses other and other current liabilities.
Accrued Other and Other Current Liabilities [Member]
Commercial milestone payments.
Commercial Milestone payments
Commercial milestone payments
Assets
Business Combination, Recognized Asset Acquired, Asset [Abstract]
February 2025 Offering [Member]
February 2025 offering.
February 2025 Offering [Member]
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Vesting [Axis]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Other comprehensive loss:
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Other Receivables
Related party collaboration receivables
Liabilities
Total liabilities
Financial Instruments [Domain]
Probability of achieving certain development milestones.
Probability Of Achieving Certain Development Milestones [Member]
Probability of Achieving Certain Development Milestones [Member]
Restricted cash
Restricted Cash
Restricted Cash, Total
Warrants exercised
Class Of Warrant Or Rights Exercised
Class of warrant or rights exercised.
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Recently issued accounting pronouncements not yet adopted.
Recently Issued Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Recently Issued Accounting Pronouncements Not Yet Adopted
Current liabilities:
Business Combination, Recognized Liability Assumed, Liability, Current [Abstract]
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average shares of common stock outstanding, diluted
Weighted average shares of common stock outstanding, used to compute diluted net loss per share
Securities Act File Number
Entity File Number
Percentage of option to fund of development cost.
Percentage Of Option To Fund Of Development Cost
Percentage of option to fund of development cost
Unrealized gain (loss) on available-for-sale securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized loss on available-for-sale securities
Cover [Abstract]
Expected volatility, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Measurement Input Type [Axis]
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Prepaid expenses and other current assets
Forfeitures
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Percentage of number of shares outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Fair Value, Measurement with Unobservable Inputs Reconciliation, Liability, Transfers out of Level 3
Fair value, liabilities, transfers out of level 3, amount
Subleased description
Subleased description.
Scenario [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Number of shares authorized for common stock for equity awards
Number of operating segment
Number of Operating Segments
Sale of Stock [Domain]
Sale of Stock
Segment Reporting Disclosure [Text Block]
Segment Reporting
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
General and administrative expense
Share-Based Payment Arrangement, Performance Shares, Activity [Table Text Block]
Summary of Performance Stock Units Activity
Share based compensation arrangement by share based payment award offering period.
Share Based Compensation Arrangement By Share Based Payment Award Offering Period
Offering period
Related party transaction.
Related Party Transaction Policy [Text Block]
Related Parties
Paul Herzich [Member]
Paul Herzich.
Paul Herzich [Member]
Accounts payable
Business Combination, Recognized Liability Assumed, Accounts Payable, Current
Adjustments to Additional Paid in Capital, Warrant Issued
Issuance of pre-funded warrants in public offering/private placement
Common stock price
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions Common Stock Price
Share-based compensation arrangement by share-based payment award, fair value assumptions common stock price.
External General And Administrative Expense [Member]
External general and administrative expense.
External General and Administrative Expense [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Vested and expected to vest at March 31, 2026
Accrued Research And Development Expense [Member]
Accrued research and development expense.
Accrued Research and Development Expenses [Member]
Accrual recorded as a result of restructuring charges
Restructuring charges
Restructuring Charges
Restructuring Charges, Total
Remaining Contractual Life (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Issuance of common stock to related party in connection with stock purchase agreement.
Issuance Of Common Stock To Related Party In Connection With Stock Purchase Agreement
Issued and sold shares of common stock
Issuance of common stock in connection with employee stock purchase plan, units
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Fair value asset level 2 to level 1 transfers amount.
Fair Value Asset Level 2 To Level 1 Transfers Amount
Fair value, assets, level 2 to level 1 transfers, amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Total liabilities
Business Combination, Recognized Liability Assumed, Liability
Financial Liabilities Fair Value Disclosure [Abstract]
Risk-free rate, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Unrecognized equity-based compensation
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Operating Lease, Liability, Current
Operating lease liabilities, current
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
At The Market Public Offering [Member]
At the market public offering.
At-the-Market Public Offering [Member]
Document Transition Report
Document Transition Report
Share-Based Payment Arrangement, Additional Disclosure [Abstract]
Operating Expenses
Total operating expenses
Research and Development Expense
Research and development
Research and Development Expense, Total
Research and development expense
Amended and Restated 2020 Equity Incentive Plan [Member]
Amended and Restated Two Thousand And Twenty Equity Incentive Plan [Member]
Amended and restated 2020 equity incentive plan member.
Restructuring Charges [Abstract]
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest
Comprehensive loss
Statement of Cash Flows [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value
Stock Issued During Period, Value, New Issues
Issuance of common stock, net of issuance costs
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Assets, Fair Value Disclosure [Abstract]
Financial assets
Equity [Text Block]
Stockholders' Equity
Earnings Per Share [Text Block]
Net Loss Per Share
Operating lease liabilities
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Current Liabilities Operating lease liabilities
Business combination recognized identifiable assets acquired and liabilities assumed current liabilities operating lease liabilities.
Summary of Restricted Stock Unit Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Outstanding, Aggregate Intrinsic Value
2020 equity incentive plan.
Two Thousand And Twenty Equity Incentive Plan [Member]
2020 Equity Incentive Plan [Member]
Two thousand and twenty one employee stock purchase plan.
Two Thousand And Twenty One Employee Stock Purchase Plan [Member]
2021 Employee Stock Purchase Plan [Member]
Transaction price.
Transaction Price
Transaction price
Expected dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Earnings Per Share Basic [Line Items]
First development milestone payable
First development milestone payable.
S G T 003 [Member]
SGT-003.
SGT-003 [Member]
Office and laboratory lease.
Office And Laboratory Lease [Member]
Office and Laboratory Lease [Member]
Assets [Abstract]
Assets
Risk-free rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other assets
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Interest Expense, Nonoperating, Total
Interest Expense, Nonoperating
Interest expense
Business Acquisition, fair value
Business Combination, Achieved in Stages, Preacquisition Equity Interest in Acquiree, Fair Value
Research and Development Expense [Member]
Research and Development [Member]
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Available-for-Sale Securities
Upfront license fee.
Upfront License Fee
Upfront license fee
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Summary of Changes in Balances of Company's Related Party Collaboration Receivables and Contract Liabilities
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Schedule of Prepaid Expenses and Other Current Assets
Agreement date
Asset Acquisition, Date of Acquisition Agreement
Restructuring Cost and Reserve [Line Items]
Payments of principal portion of finance lease obligations
Repayment of Long-Term Debt, Long-Term Lease Obligation, and Capital Security
Repayment of Long-Term Debt, Long-Term Lease Obligation, and Capital Security, Total
November 2022 Plan [Member]
November 2022 Plan Member
November 2022 Plan.
Gain on acquisition of business
Gain on acquisition
Gain (Loss) On Acquisition Of Business
Gain (loss) on acquisition of business.
Proceeds from Stock Options Exercised
Proceeds from exercises of common stock options
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Net Income (Loss) Available to Common Stockholders, Basic
Net loss attributable to common stockholders
Net Income (Loss) Available to Common Stockholders, Basic, Total
Net assets acquired
Net assets acquired
Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less)
Payments Of Common Stock And Pre Funded Warrants Issuance Costs In Public Offering
Payments of common stock and pre funded warrants issuance costs in public offering.
Payments of common stock and pre-funded warrants issuance costs in public offering
Net loss before taxes
Business Combination, Pro Forma Information, Pro Forma Income (Loss) from Continuing Operations, after Tax
Share-Based Payment Arrangement [Abstract]
Assets, Fair Value Disclosure
Total financial assets
Sale of Stock [Axis]
Sale of Stock
Derivatives, Policy [Policy Text Block]
Derivative liabilities
Revenues, Total
Revenues
Collaboration revenue - related party
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by (used in) investing activities
Transaction price determined under ASC 606
Transaction Price Determined Under A S C 606
Transaction price determined under ASC 606.
Private Placement [Member]
Private Placement [Member]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Fair value, assets, transfers into level 3, amount
Title of 12(b) Security
Title of 12(b) Security
Forfeitures
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeitures
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Money Market Funds [Member]
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Income Tax Disclosure [Text Block]
Income Taxes
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Restructuring Plan [Domain]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Business acquisition, share price
Business Combination, Price Per Share
Property, Plant and Equipment [Table Text Block]
Summary of Property and Equipment, Net
Letter of credit amount
Letter of credit outstanding amount
Letters of Credit Outstanding, Amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Outstanding at March 31, 2026
Outstanding at January 1, 2026
Income Tax Disclosure [Abstract]
April 2022 Plan [Member]
April 2022 Plan Member
April 2022 Plan.
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Accrued Liabilities and Other Liabilities [Abstract]
Acquisition
Business Combination [Text Block]
Unrecognized Tax Benefits
Unrecognized tax benefits
Unrecognized Tax Benefits, Beginning Balance
Unrecognized Tax Benefits, Ending Balance
Additional Paid-in Capital [Member]
Additional Paid in Capital [Member]
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Accrued expenses and other liabilities
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Change in fair value of derivative liabilities
Liabilities, Fair Value Adjustment
Gain (losses) recorded for a change in fair value
Common stock issuable upon exercise of prefunded warrants
Common Stock Issuable Upon Exercise of Prefunded Warrants
Common stock issuable upon exercise of pre-funded warrants
Recently issued accounting pronouncements
Recently issued accounting pronouncements.
Recently Issued Accounting Pronouncements [Policy Text Block]
Recently Issued Accounting Pronouncements
Risk-free rate, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Subsequent Event Type [Axis]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Entity Ex Transition Period
Entity Ex Transition Period
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Equity Components [Axis]
Equity Components
Unvested Stock Options [Member]
Unvested Stock Options [Member]
Unvested stock options member.
Total other income, net
Nonoperating Income (Expense)
Other income (expense), net
2018 Omnibus Incentive Plan.
Two Thousand And Eighteen Omnibus Incentive Plan [Member]
2018 Omnibus Incentive Plan [Member]
Equity Component [Domain]
Equity Component
Jessie Hanrahan Ph. D. [Member]
Jessie Hanrahan Ph. D.
Jessie Hanrahan Ph. D. [Member]
Business Combination [Axis]
Class of warrant or right price per share.
Class Of Warrant Or Right Price Per Share
Common stock warrants price per share
IPO [Member]
Public Offering [Member]
Government Bonds Maturing in One Year or Less [Member]
Government Bonds.
Government Bonds [Member]
Issuance of common stock under employee stock purchase plan, units
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Depreciation, Depletion and Amortization, Nonproduction
Depreciation, Depletion and Amortization, Nonproduction, Total
Depreciation and amortization expense
Statement of Comprehensive Income [Abstract]
Accrued Expenses And Other Current Liabilities [Table]
Accrued Expenses And Other Current Liabilities [Table]
Accrued Expenses And Other Current Liabilities [Table]
Maximum [Member]
Maximum [Member]
Statistical Measurement [Axis]
Statistical Measurement
Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
One-Time Employee Termination Benefits [Member]
One-time Termination Benefits [Member]
April 2022 Corporate Strategy Change [Member]
April 2022 Corporate Strategy Change [Member]
April 2022 Corporate Strategy Change.
Common Stock, Value, Issued
Common stock, $0.001 par value - 240,000,000 shares authorized at March 31, 2026 and December 31, 2025; 98,394,720 and 78,967,888 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively
Service Based Awards [Member]
Service Based Awards [Member]
Service based awards.
Accrued other.
Accrued Expenses And Other [Member]
Accrued Other [Member]
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Kevin Tan [Member]
Kevin Tan.
Kevin Tan [Member]
Percentage of net income and net losses on net sales.
Percentage Of Net Income And Net Losses On Net Sales
Percentage of net income and net losses on net sales
Shares Subject to Employee Stock Purchase Plan [Member]
Employee Stock [Member]
Business Combination [Table]
Entity Registrant Name
Entity Registrant Name
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Loss
Restructuring Costs [Abstract]
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income, net
Subsequent Events [Abstract]
Agreement termination notice period.
Agreement Termination Notice Period
Agreement termination notice period
Income Tax Expense (Benefit)
Income tax expense (benefit)
Income Tax Expense (Benefit), Total
Asset acquisition, assumed regulatory milestone payments.
Asset Acquisition, Assumed Regulatory Milestone Payments
Assumed regulatory milestone payments
Milestone Liability Payment
Milestone liability payment.
Milestone payment
Cumulative developmental, regulatory, and commercial milestone payments.
Cumulative Developmental, Regulatory, and Commercial Milestone Payments
Cumulative developmental, regulatory, and commercial milestone payments
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Fair value, assets, transfers out of level 2, amount
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 2
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 2.
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Equity-based compensation
Compensation Related Costs, Policy [Policy Text Block]
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income
Consolidation Items [Axis]
Amounts paid during the period
Amounts paid during the period
Restructuring charges were paid
Payments for Restructuring
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Assets
Total assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable at March 31, 2026
Income Statement [Abstract]
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]
Restructuring Cost [Table]
At-the-market offering sales agreement member.
At-the-Market Offering Sales Agreement [Member]
At-the-Market Offering Sales Agreement [Member]
Percentage of outstanding common stock.
Percentage Of Outstanding Common Stock
Percentage of outstanding common stock
Weighted Average [Member]
Average [Member]
March 2026 Private Placement [Member]
March 2026 Private Placement.
Development Milestone Payable
Development milestone payable .
Development milestone payable
Stock issued and sold
Common stock shares issued
Issuance of common stock, net of issuance costs, units
Vested
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Business Combination [Abstract]
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share, diluted
Operating Segments [Member]
Operating segment [Member]
Asset Acquisition [Axis]
City Area Code
City Area Code
Inducement Award [Member]
Inducement Award [Member]
Inducement award.
Operating and financing leases.
Operating And Financing Leases Disclosure [Text Block]
Leases
Revenues
Business Combination, Pro Forma Information, Pro Forma Revenue
Vesting of restricted stock units.
Vesting Of Restricted Stock Units
Vesting of restricted stock, units
Finance Lease, Liability, Noncurrent
Finance lease liabilities, excluding current portion
Business Combination [Line Items]
Counterparty Name [Domain]
Counterparty Name
Treasury Bills Maturing in One Year or Less [Member]
Treasury Bills [Member]
Treasury bill.
Treasury Bill [Member]
Pre-funded warrants outstanding.
Pre Funded Warrants Outstanding
Pre-funded warrants outstanding
Issuance of common stock under employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Derivative Liability, Current
Derivative liabilities
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Remaining accrued restructuring charges to be paid in next three months.
Remaining Accrued Restructuring Charges To Be Paid In Next Three Months
Remaining accrued restructuring charges to be paid in next three months
Corporate Bond Securities [Member]
Corporate Bond Securities [Member]
Operating Income (Loss)
Loss from operations
Pre-funded warrants.
Pre Funded Warrants [Member]
Pre-Funded Warrants [Member]
Retained Earnings [Member]
Accumulated Deficit [Member]
Cash and Cash Equivalents [Axis]
Total non-current assets
Assets, Noncurrent
Share-Based Payment Arrangement, Noncash Expense
Equity-based compensation expense
Share-Based Payment Arrangement, Noncash Expense, Total
Volatility [Member]
Measurement Input, Price Volatility [Member]
Payments of Stock Issuance Costs
Payments of common stock and pre-funded warrants issuance costs in private placement
Milestone payments upon achievement of net sales milestones.
Milestone Payments Upon Achievement Of Net Sales Milestones
Milestone Payments upon achievement of net sales milestones
Total non-current liabilities
Liabilities, Noncurrent
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 1
Class of Stock [Line Items]
Class Of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Increase (decrease) in right of use asset due to lease termination.
Increase Decrease In Right Of Use Asset Due To Lease Termination
Decrease in right-of-use assets due to lease termination
Asset Acquisition [Abstract]
November 2022 Workforce Reduction plan [Member]
November 2022 Workforce Reduction plan [Member]
November 2022 Workforce Reduction plan.
Other income, net:
Nonoperating Income (Expense) [Abstract]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Calculation of Diluted Net Loss per Share
Schedule of Antidilutive Securities Excluded from Calculation of Net Loss
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Asset Acquisition [Line Items]
Securities Purchase Agreement.
Securities Purchase Agreement [Member]
Securities Purchase Agreement [Member]
Accretion (Amortization) of Discounts and Premiums, Investments
Amortization of discount on available-for-sale securities
Number of shares of common stock
Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares
S G T 501 [Member]
SGT-501.
SGT-501 [Member]
Total cash equivalents
Cash Equivalents, at Carrying Value
Cash Equivalents, at Carrying Value, Total
Entity Tax Identification Number
Entity Tax Identification Number
Operating lease liabilities, excluding current portion
Business Combination, Recognized Identifiable Asset Acquired and Liability Assumed, Operating lease liabilities, excluding current portion
Business combination, Recognized identifiable asset acquired and liability assumed, Operating lease liabilities, excluding current portion.
Warrants issued
Warrants Issued
Warrants issued.
Incentive Stock Options [Member]
Incentive stock options.
Local Phone Number
Local Phone Number
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Proceeds from issuance of common stock and pre-funded warrants in private placement.
Proceeds from Issuance of Common Stock and Pre-funded Warrants in Private Placement
Proceeds from issuance of common stock and pre-funded warrants in private placement
Other Liabilities, Current
Other current liabilities
Milestone payments upon achievement of development milestone.
Milestone Payments Upon Achievement Of Development Milestone
Milestone payments upon achievement of development milestone
Milestone payment upon achievement of certain milestones.
Milestone Payment Upon Achievement Of Certain Milestones
Milestone payment upon achievement of certain milestones
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Issuance costs
Accounting Policies [Abstract]
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Schedule Of Earnings Per Share Basic By Common Class [Table]
Fair value measurement with unobservable inputs reconciliation recurring basis liability transfers in to level 2.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Transfers In to Level 2
Fair value, liabilities, transfers into level 2, amount
Internal Research And Development Expense [Member]
Internal research and development expense.
Internal Research and Development Expense [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Number of shares available for future issuance
Unrecognized equity-based compensation cost, weighted average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Cash, cash equivalents and available-for-sale securities
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest at March 31, 2026