Stockholders' Equity - Company's Shares of Common Stock Reserved for Issuance (Detail) - shares	Mar. 31, 2026	Dec. 31, 2025
Class Of Warrant Or Right [Line Items]
Total shares reserved	68,351,663	68,826,467
April 2017 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	24,725	24,725
June 2017 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	41,736	41,736
December 2018 Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	11,332	11,332
Pre-Funded PIPE Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	3,615,516	3,615,516
2021 Pre-funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	32,175,172	32,175,172
2023 Pre-funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	5,666,667	5,666,667
2025 Pre-funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	7,142,857	7,142,857
Stock Options [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	12,873,658	13,243,462
Issued and nonvested RSUs [Member]
Class Of Warrant Or Right [Line Items]
Total shares reserved	6,800,000	6,905,000