v3.26.1
Segments (Tables)
 3 Months Ended
Mar. 31, 2026
Segment Reporting [Abstract]  
Schedule of Significant Expense Categories Reviewed by CODM The following table summarizes the significant expense categories regularly reviewed by the CODM for the three months ended March 31, 2026 and 2025.

 

 

 

Three months ended March 31

 

(in thousands)

 

2026

 

 

2025

 

Revenue

 

$

4,580

 

 

$

—

 

 

 

 

 

 

 

 

Operating expenses:

 

 

 

 

 

 

Research and development

 

 

 

 

 

 

JAK2 V617F

 

 

1,412

 

 

 

1,175

 

KAT6A

 

 

791

 

 

 

506

 

Discovery programs

 

 

54

 

 

 

787

 

Other

 

 

838

 

 

 

9,901

 

General costs, including personnel related

 

 

10,506

 

 

 

16,447

 

Total research and development

 

 

13,601

 

 

 

28,816

 

General and administrative

 

 

5,156

 

 

 

5,790

 

Total operating expenses

 

$

18,757

 

 

$

34,606

 

Loss from operations

 

 

(14,177

)

 

 

(34,606

)

Other income, net

 

 

3,792

 

 

 

2,521

 

Net loss

 

$

(10,385

)

 

$

(32,085

)