75000 - Document - Document and Entity Information
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75010 - Statement - Consolidated Balance Sheets (Unaudited)
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75020 - Statement - Consolidated Balance Sheets (Parenthetical) (Unaudited)
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75030 - Statement - Consolidated Statements of Loss and Comprehensive Loss (Unaudited)
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75040 - Statement - Consolidated Statements of Cash Flows (Unaudited)
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75050 - Statement - Consolidated Statements of Stockholder's Equity (Unaudited)
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995455 - Disclosure - Nature of Business, Basis of Presentation and Liquidity Risk
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995465 - Disclosure - Accounting Policies
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995475 - Disclosure - Government Grant
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995485 - Disclosure - Intangible Assets
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995495 - Disclosure - License Agreements
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995505 - Disclosure - Fair Value Measurements
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995515 - Disclosure - Convertible Debt
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995525 - Disclosure - Common Stock
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995535 - Disclosure - Related Party Transactions
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995545 - Disclosure - Commitments and Contingencies
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995555 - Disclosure - Subsequent Events
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995565 - Disclosure - Accounting Policies (Policies)
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995575 - Disclosure - Intangible Assets (Tables)
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995585 - Disclosure - Fair Value Measurements (Tables)
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995595 - Disclosure - Convertible Debt (Tables)
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995605 - Disclosure - Common Stock (Tables)
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995615 - Disclosure - Commitments and Contingencies (Tables)
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995625 - Disclosure - Nature of Business, Basis of Presentation and Liquidity Risk - Additional Information (Detail)
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995635 - Disclosure - Government Grant - Additional Information (Details)
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995645 - Disclosure - Intangible Assets - Additional Information (Detail)
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995655 - Disclosure - Intangible Assets - Components of Intangible Assets (Detail)
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995665 - Disclosure - Intangible Assets - Estimated Future Amortization Expense Related to Intangible Assets (Detail)
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995675 - Disclosure - License Agreements - Additional Information (Detail)
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995685 - Disclosure - Fair Value Measurements - Additional Information (Detail)
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995695 - Disclosure - Fair Value Measurements - Summary of Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail)
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995705 - Disclosure - Fair Value Measurements - Summary of Money Market Securities (Detail)
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995715 - Disclosure - Fair Value Measurements - Schedule of Corporate Bonds and Commercial Paper (Details)
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995725 - Disclosure - Fair Value Measurements - Schedule of Aggregate Fair Value of Principal Amount of Convertible Debt (Detail)
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995735 - Disclosure - Fair Value Measurements - Schedule of Changes in Fair Value of Liabilities (Details)
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995745 - Disclosure - Convertible Debt - Additional Information (Details)
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995755 - Disclosure - Convertible Debt - Schedule of Convertible Term Loan Balance Including Convertible Debt Balance (Details)
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995765 - Disclosure - Common Stock - Authorized - Additional Information (Detail)
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995775 - Disclosure - Common Stock - Issued and Outstanding Shares - Additional Information (Detail)
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995785 - Disclosure - Common Stock - Open Market Sales Agreement - Additional Information (Detail)
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995795 - Disclosure - Common Stock - Public Offering - Additional Information (Detail)
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995805 - Disclosure - Common Stock - Equity Awards - Additional Information (Detail)
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995815 - Disclosure - Common Stock - Summary of Stock Options Activity (Detail)
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995825 - Disclosure - Common Stock - Summary of Fair Value of Each Stock Award for Employees and Directors (Detail)
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995835 - Disclosure - Common Stock - Summary of Stock-Based Compensation Expense (Detail)
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995845 - Disclosure - Common Stock - Loss Per Common Share - Additional Information (Details)
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995855 - Disclosure - Common Stock - Restricted Stock Unit Awards - Additional Information (Detail)
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995865 - Disclosure - Common Stock - Summary of Restricted Stock Unit Award Activity (Detail)
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995875 - Disclosure - Common Stock - Employee Share Purchase Plan - Additional Information (Detail)
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995885 - Disclosure - Common Stock - Summary of Outstanding Warrants (Detail)
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995895 - Disclosure - Common Stock - Stock Warrants - Additional Information (Detail)
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995905 - Disclosure - Related Party Transactions (Additional Information) (Details)
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995915 - Disclosure - Commitments and Contingencies - Summary of Contractual Obligations (Detail)
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995925 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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995935 - Disclosure - Commitments and Contingencies - Summary of Other Information Related to Leases (Detail)
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995945 - Disclosure - Subsequent Events - Additional Information (Details)
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Weighted-Average Grant Date Fair Value, Released
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Beginning Balance
Restricted shares reserved for issuance under incentive plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred stock, shares issued
Preferred Stock, Shares Issued
Entity Addresses [Table]
Expenses related to indemnification issues
Indemnification Expense
Indemnification expense.
Loss on contingent consideration
Change in fair value of contingent consideration [note 4 and note 5]
Change in fair value of contingent consideration [note 4 and note 5]
Change in fair value of contingent consideration [note 4 and note 5]
Gain (loss) on contingent consideration
Plan Name
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Pike [Member]
Pike [Member]
Pike.
Proceeds from exercise of warrants
Proceeds from exercise of warrants
Proceeds from Warrant Exercises
Warrants Issued In June Two Thousand Twenty Five [Member]
Warrants issued in June two thousand twenty five.
Warrants Issued in June 2025 [Member]
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Restricted cash [Member]
Restricted Cash [Member]
Restricted cash.
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, shares authorized
Common Stock, Shares Authorized
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2029
Short-Term Investments
Investment, Policy [Policy Text Block]
Fair Value by Liability Class [Domain]
Document Fiscal Period Focus
Document Fiscal Period Focus
Convertible debt, stated rate
Convertible debt compound interest
Debt Instrument, Interest Rate, Stated Percentage
Entity Shell Company
Entity Shell Company
Total
Contractual Obligation
Accrued liabilities other
Other Accrued Liabilities, Current
Convertible Debt [Member]
Convertible Debt [Member]
Forfeiture rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Forfeiture Rate
Share based compensation arrangement by share based payment award fair value assumptions expected forfeiture rate.
Cash,cash equivalents and short-term investments
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalent
Cash and cash equivalents [note 5]
Regulatory Agency
Regulatory Agency [Domain]
Common stock, shares issued
Common Stock, Shares, Issued
Lease agreement
Lessee, Operating Lease, Description
Asset Class
Asset Class [Domain]
Statement [Table]
Statement [Table]
Operating leases
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Business Combination, Contingent Consideration, Liability, Measurement Input [Extensible Enumeration]
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock [Member]
Series A convertible preferred stock.
Research And Development To Related Parties
Research and development to related parties.
Research and development - related parties [note 8]
Area of office space leased
Area Of Office Space Leased
Area of office space leased.
Statement [Line Items]
Statement [Line Items]
Maturity Period Of Securities
Maturity period of securities
Maturity period of securities.
Weighted Average Exercise Price, Expired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Warrant [Member]
Warrant [Member]
Common Warrants
Entity Filer Category
Entity Filer Category
Total liabilities and stockholders' equity
Liabilities and Equity
Increase (Decrease) in Employee Related Liabilities, Total
Accrued compensation
Increase (Decrease) in Employee Related Liabilities
Purchase of marketable securities
Payments to Acquire Marketable Securities
Related Party Consulting Fee Incurred
Related party consulting fee incurred.
Consulting fees incurred
Employees and Consultants [Member]
Employees And Consultants [Member]
Employees and consultants.
Share issued, price per share
Common stock, price per share
Shares Issued, Price Per Share
Subsequent Event [Line Items]
Goodwill, Ending Balance
Goodwill, Beginning Balance
Goodwill, Total
Goodwill
Goodwill
Stock Options
Interest income
Investment Income, Interest
Convertible Debt [Table]
Convertible Debt [Table]
Convertible debt.
Proceeds from Convertible Debt
Receipt of 2024 SVB convertible term loan less transaction costs [note 6]
Geographical
Geographical [Domain]
Assets, Noncurrent [Abstract]
Non-current assets:
Financing costs
Adjustments To Additional Paid In Capitals Additional Costs To Financings Charged To APIC
Adjustments to additional paid in capitals additional costs to financings charged to APIC.
Pre Funded Warrants [Member]
Pre-funded warrants.
Pre-Funded Warrants
Additional paid-in capital
Additional Paid in Capital, Common Stock
Debt Issuance Costs, Net
Transaction costs
Related Parties
Adare Pharma Solutions [Member]
Related Parties [Member]
Accounting Policies
Significant Accounting Policies [Text Block]
Intangible assets, Useful life
Finite-Lived Intangible Asset, Useful Life
Grant awarded
Grant Awarded
Grant awarded.
Two Thousand Twenty Three Non Employee Director Equity Incentive Plan.
Two Thousand Twenty Three Non Employee Director Equity Incentive Plan [Member]
2023 Non Employee Director Equity Incentive Plan [Member]
Nonrelated Party [Member]
Number of Optioned Common Shares, Granted
Number of shares granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Operating lease, initial monthly base rent expenses
Operating Lease Initial Monthly Base Rent Expenses
Operating lease, initial monthly base rent expenses.
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Basic net loss per common share [note 7[d]]
Common stock available for sale under offering
Common Stock Shares Available For Future Grant
Common stock, shares available for future grant.
Other Comprehensive Income (Loss), before Tax [Abstract]
OTHER COMPREHENSIVE LOSS
Percentage of outstanding shares of common stock.
Percentage of Outstanding Shares of Common Stock
Percentage of outstanding shares of common stock
Common shares reserved for options currently outstanding
Number of Optioned Common Shares, Beginning Balance
Number of Optioned Common Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Reimbursements received.
Reimbursements Received
Reimbursements received.
Total current liabilities
Liabilities, Current
Net cash proceeds from the sale and issuance of equity securities
Net cash proceeds from the issuance equity interests
Proceeds from Sale of Equity Securities, FV-NI
Stockholders' equity:
Equity, Attributable to Parent [Abstract]
Entity Small Business
Entity Small Business
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Other Commitments [Line Items]
Other Commitments [Line Items]
Preferred stock [Member]
Preferred Stock [Member]
Grant receivable
Grant receivable [note 3]
Grants Receivable, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of Optioned Common Shares, Cancelled/Forfeited
Number of Optioned Common Shares, Cancelled/Forfeited
Sale of Stock, Price Per Share
Sale of common stock and warrant, public offering price
Sale of stock, Offering price per unit
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Reduction in R&D expense
Research And Development Expenses Increase Decrease
Research and development expenses increase (decrease).
Registration Rights Agreement [Member]
Registration Rights Agreement [Member]
Registration rights agreement.
Amendment Flag
Amendment Flag
Security Owned and Sold, Not yet Purchased, at Fair Value [Axis]
Warrants to purchase common stock
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
LIABILITIES AND STOCKHOLDERS’ EQUITY
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Board of Directors [Member]
Board Of Directors [Member]
Board of directors.
Net cash used in operating activities
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
July 2020 Registered Direct Offering [Member]
Direct Offering [Member]
Direct offering.
Direct Offering [Member]
Common Stock [Member]
Common Stock [Member]
Weighted Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Exercise price per share
Government Grant [Line Items]
Government Grant [Line Items]
Government grant.
Business Combination, Contingent Consideration, Liability, Measurement Input
Measurement Input
Entity Address, Address Line One
Entity Address, Address Line One
Summary of Fair Value of Each Stock Award for Employees and Directors
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Maximum number of shares authorized to purchased
Share Based Compensation Maximum Number Of Shares Authorized To Purchased
Share based compensation, maximum number of shares authorized to purchased.
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Government Grant [Table]
Government Grant [Table]
Government grant.
2010 Performance Incentive Plan [Member]
Two Thousands And Ten Performance Incentive Plan [Member]
Information pertaining to 2010 performance incentive plan.
November2022 Private Placement.
November 2022 Private Placement [Member]
November 2022 Private Placement [Member]
Other Assets And Restricted Cash
Other assets and restricted cash.
Other assets and restricted cash [note 5]
Operating Lease, Right-of-Use Asset
Right-of-use assets [note 9]
Indemnification obligations
Guarantor Obligations, Current Carrying Value
Class of Warrant or Right
Class of Warrant or Right [Axis]
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Public Offering [Member]
Public Offering.
Public Offering [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
June Twenty Twenty Five Public Offering [Member]
June twenty twenty five public offering.
June 2025 Public Offering [ Member]
Underwriting Discounts
Underwriting discounts.
Underwriting discounts
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase (decrease) in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Anti-dilutive securities excluded from earning per share computation
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Pre-Funded Warrants Issued in August 2020 [Member]
Warrants Issued In August Two Thousand Twenty [Member]
Warrants issued in August two thousand twenty.
Sopharma
Sopharma [Member]
Common stock, par value
Common Stock, Par or Stated Value Per Share
Security deposit
Security Deposit
Operating Costs and Expenses
Operating Costs and Expenses, Total
Expenses incurred
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Estimated Fair Value
Debt Securities, Available-for-Sale
Estimated Fair Value
Debt Disclosure [Abstract]
Number of Securities Exercised Overallotment Option to Purchase
Number of securities exercised overallotment option to purchase.
Number of securities exercised overallotment option to purchase
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Accrued liabilities
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Ownership [Domain]
Current Fiscal Year End Date
Current Fiscal Year End Date
Lease, security deposit, annual payment
Lease Security Deposit Annual Payment
Lease security deposit annual payment.
Document Quarterly Report
Document Quarterly Report
Receivables [Abstract]
Fair Value By Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Entity Address, State or Province
Entity Address, State or Province
Number of Shares, Beginning Balance
Number of Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of Shares, Beginning Balance
Number of Shares, Ending Balance
Increase (Decrease) in Other Accrued Liabilities
Accrued liabilities, other
Threshold consecutive trading days
Debt Instrument, Convertible, Threshold Consecutive Trading Days
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Total
Class of Warrant or Right
Class of Warrant or Right [Domain]
Geographical [Axis]
Geographical
Line of Credit Facility, Lender
Line of Credit Facility, Lender [Domain]
Marketable securities [note 5]
Marketable Securities, Current
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Stock-Based Compensation Expense
Lease, security deposit payment remaining amount
Lease Security Deposit Thereafter
Lease security deposit thereafter.
License Agreements
Collaborative Arrangement Disclosure [Text Block]
2018 Equity Incentive Plan [Member]
Two Thousand And Eighteen Equity Incentive Plan [Member]
Two thousand and eighteen equity incentive plan.
Proceeds from Sale and Maturity of Marketable Securities
Maturities of marketable securities
Subsequent Event [Member]
Subsequent event [Member]
Subsequent Event
June 2025 Public Offering [Member]
June 2025 Public Offering [Member]
June 2025 public offering.
Share holding percentage of shares issued and outstanding.
Share holding percentage of shares issued and outstanding
Share Holding Percentage Of Shares Issued And Outstanding
Antidilutive Securities
Antidilutive Securities [Axis]
Number of Optioned Common Shares, Expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Vesting percentage
More than 5 years
Contractual Obligation, to be Paid, after Year Five
Accrued Interest On S V B Convertible Debt
Accrued interest on SVB convertible debt.
Accrued interest on 2023 SVB convertible term loan [note 6]
Seattle Lease Arrangement [Member]
Seattle Office Operating Lease [Member]
Seattle office operating lease.
Lease agreement commencement date
Lease Agreement Commencement Date
Lease agreement commencement date.
Accumulated other comprehensive income (loss) [Member]
AOCI Attributable to Parent [Member]
Finite-Lived Intangible Assets, Major Class Name
Finite-Lived Intangible Assets, Major Class Name [Domain]
Cash and Cash Equivalents [Domain]
Other Commitments [Table]
Other Commitments [Table]
Operating lease, option to extend, description
Lessee, Operating Lease, Option to Extend
Convertible Debt, Current
Current portion of convertible debt [note 5 and note 6]
Convertible preferred stock, value
Preferred Stock, Value, Issued
Maturity date
Debt Instrument, Maturity Date
Minimum [Member]
Minimum [Member]
Minimum
Weighted-Average Grant Date Fair Value, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
License agreement amortization expense
Amortization of Intangible Assets
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Liabilities, Fair Value Disclosure [Abstract]
Liabilities
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Summary of Assets and Liabilities Measured at Fair Value on Recurring Basis
Schedule of Corporate Bonds and Commercial Paper
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Current liabilities:
Liabilities, Current [Abstract]
New Convertible Term Loan Member
New Convertible Term Loan [Member]
Placement agent fees and offering expenses
Placement Agent Fees And Offering Expenses
Placement agent fees and offering expenses.
Related Party Transactions [Abstract]
Operating lease, extension term
Lessee, Operating Lease, Renewal Term
Restricted Cash and Cash Equivalents, Total
Restricted Cash and Cash Equivalent
Total money market securities
Proceeds from Stock Plans
Proceeds from employee share purchase plan
Commitments and Contingencies
Commitments and contingencies [note 9]
Stock issued during period shares restricted stock unit settlement withheld and retired to treasury.
Stock Issued During Period Shares Restricted Stock Unit Settlement Withheld And Retired To Treasury
Restricted stock unit settlements withheld and retired to treasury, Shares
Weighted-Average Grant Date Fair Value, Ending Balance
Weighted-Average Grant Date Fair Value, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Ending Balance
Weighted-Average Grant Date Fair Value, Beginning Balance
Prepayment fee percentage on or after first anniversary
Debt Prepayment Fee Percentage On Or After First Anniversary
Debt prepayment fee percentage on or after first anniversary.
General and administrative [Member]
General and Administrative Expense [Member]
Convertible debt, interest rate
Debt Instrument, Basis Spread on Variable Rate
Convertible debt.
Convertible Debt [Line Items]
Convertible Debt [Line Items]
Cash paid for amounts included in the measurement of lease liabilities:
Cash Flow, Operating Activities, Lessee [Abstract]
Equity Instrument Convertible Beneficial Ownership Percentage for Exercise Option
Equity instrument convertible beneficial ownership percentage for exercise option.
Equity instrument, convertible beneficial ownership percentage for exercise by holder
Performance restricted share unit.
PRSUs
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Effect of exchange rate changes on cash
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Jefferies Open Market Sale Agreement [Member]
Jefferies open market sale agreement.
NIDA
National Institute On Drug Abuse [Member]
National Institute on Drug Abuse.
Long-Term Debt, Type
Long-Term Debt, Type [Domain]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average shares used in computation of basic net loss per common share [note 7[d]]
ORCA-V1 Clinical Study Costs
O R C A V1 Clinical Study Costs [Member]
ORCA-V1 Clinical study costs.
Document Information [Line Items]
Additional number of shares to be issued accompanying warrants
Additional Number of Securities Called by Warrants or Rights
Additional number of securities called by warrants or rights.
General And Administrative To Related Parties
General and administrative to related parties.
General and administrative - related parties [note 8]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Operating Leased Assets [Table]
Schedule of Operating Leased Assets [Table]
Proceeds from Issuance of Private Placement
Net proceeds
Subsequent Events [Text Block]
Subsequent Events
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Cash
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Business Combination, Contingent Consideration, Liability, Current
Current contingent consideration [note 4 and note 5]
Variable Rate [Domain]
Variable Rate
Total stockholders' equity
Beginning Balance
Ending Balance
Equity, Attributable to Parent
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Lessee, Operating Lease, Existence of Option to Extend [true false]
Lessee, Operating Lease, Existence of Option to Extend [true false]
Prepayment fee percentage on original aggregate principal
Debt Prepayment Fee Percentage On Original Aggregate Principal
Debt Prepayment Fee Percentage On Original Aggregate Principal
Statement of Stockholders' Equity [Abstract]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Proceeds From Issuance Of Private Placement Gross Before Deducting Placement Agent Fees and other Expenses
Proceeds from issuance of private placement gross before deducting placement agent fees and other expenses.
Gross proceeds
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
2025
2026
Percentage of outstanding shares acquired.
Percentage of Outstanding Shares Acquired
Percentage of outstanding shares acquired
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Measurements
Fair Value Disclosures [Text Block]
2017 Equity Incentive Plan [Member]
Two Thousands And Seventeen Equity Incentive Plan [Member]
Information pertaining to 2017 equity incentive plan.
Security Owned and Sold, Not yet Purchased Fair Value, Security Name [Domain]
Debt Instrument, Name
Debt Instrument, Name [Domain]
Right-of-use assets obtained in exchange for lease obligations:
Right Of Use Assets Obtained In Exchange For Lease Obligations [Abstract]
Right-of-use assets obtained in exchange for lease obligations.
Measurement Input, Discount Rate [Member]
Measurement Input, Discount Rate [Member]
Silicon Valley Bank And S V B Innovation Credit Fund V I I I L P [Member]
SVB [Member]
Silicon Valley Bank and SVB Innovation Credit Fund VIII, L.P.
Proceeds from Issuance Public Offering
Proceeds from issuance public offering.
Proceeds from public offering, net of issuance costs
Deferred Costs, Noncurrent, Total
Deferred Costs, Noncurrent
Deferred payment
Lease, security deposit payment first anniversary
Lease Security Deposit Year One
Lease security deposit year one.
Plan Name
Plan Name [Domain]
Contingent Consideration.
Contingent Consideration [Member]
Contingent Consideration [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrants Issued in May 2019 [Member]
Warrants Issued In May Two Thousand Ninteen [Member]
WarrantsIssuedInMayTwoThousandNinteenMember.
Vancouver Lease Arrangement [Member]
Vancouver Office Operating Lease [Member]
Vancouver Office Operating Lease [Member]
Vancouver office operating lease.
Business Description and Basis of Presentation [Text Block]
Nature of Business, Basis of Presentation and Liquidity Risk
Total Outstanding and Exercisable
Class of Warrant or Right, Outstanding
Warrants to purchase common stock
Measurement input, probability of success.
Measurement Input, Probability of Success [Member]
Measurement Input, Probability of Success [Member]
Related and Nonrelated Parties [Axis]
Related party
Class Of Warrant Or Right [Table]
Class of Warrant or Right [Table]
Convertible Debt, Fair Value
Convertible Debt, Fair Value Disclosures
February 2024 Registered Direct Offering [Member]
February 2024 Registered Direct Offering [Member]
February 2024 registered direct offering.
Entity Address, City or Town
Entity Address, City or Town
Increase decrease in grants receivable.
Increase Decrease In Grants Receivable
Grant receivable
Business Combination, Contingent Consideration, Liability, Total
Business Combination, Contingent Consideration, Liability
Fair value of the contingent consideration
Contingent consideration [note 4 and note 5]
Security Exchange Name
Security Exchange Name
Regulatory Agency
Regulatory Agency [Axis]
Intangible Assets Disclosure [Text Block]
Intangible Assets
Counterparty Name
Counterparty Name [Axis]
Additional paid-in capital [Member]
Common Stock Including Additional Paid in Capital [Member]
Conversion price percentage of average closing sale price
Conversion Price Percentage Of Average Closing Sale Price
Conversion price percentage of Average closing sale price.
Measurement Input Type [Domain]
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Contingent Convertible Debt Agreement [Member]
Contingent Convertible Debt Agreement [Member]
Contingent convertible debt agreement.
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement
Statistical Measurement [Domain]
Exercise price per unit of warrant
Exercise price per Share
Exercise price per share of warrant
Total current assets
Assets, Current
Stock based compensation expense
Share-Based Payment Arrangement, Expense
Document Period End Date
Document Period End Date
Warrants Issued in November 2022 [Member]
Warrants Issued In November Two Thousand Twenty Two [Member]
Warrants Issued In November Two Thousand Twenty Two.
Title and Position [Axis]
Title of Individual
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Related Party Transaction Amounts Payable
Related party transaction amounts payable.
Amounts payable
Percentage of voting power.
Percentage Of Voting Power
Percentage of voting power
Number of shares purchased
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Purchased for Award
Statement of Financial Position [Abstract]
NIDA/NIH
National Institute On Drug Abuse And National Institutes Of Health [Member]
National institute on drug abuse and national institutes of health.
Maximum maturity period of cash and cash equivalents
Maximum Maturity Period Of Cash And Cash Equivalents
Maximum maturity period of cash and cash equivalents.
Restricted Stock Unit [Member]
Restricted Stock Units (RSUs) [Member]
RSUs
Convertible Debt Agreement [Member]
Convertible Debt Agreement.
Class of Stock
Class of Stock [Axis]
Proceeds from June 2025 public offering exercise of overallotment option, net of issuance costs [note 7b]
Proceeds From Exercise Of Overallotment Option Net Of Issuance Costs
Proceeds from exercise of overallotment option, net of issuance costs.
Total liabilities
Liabilities
Intangible assets, Fair Value
Finite-Lived Intangible Assets, Fair Value Disclosure
US Government Securities [Member]
US Government Debt Securities [Member]
Financial Instruments [Domain]
Restricted Cash
Restricted Cash, Total
Restricted cash, amortized cost and estimated fair value
Variable Rate
Variable Rate [Axis]
Finite-Lived Intangible Assets, Gross, Total
Intangible assets, Gross Carrying Value
Finite-Lived Intangible Assets, Gross
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average shares used in computation of diluted net loss per common share [note 7[d]]
Jefferies open market sales agreement.
Jefferies Open Market Sales Agreement [Member]
Entity File Number
Securities Act File Number
Virtu at-the-market sales agreement.
Virtu At-the-Market Sales Agreement [Member]
Virtu At-the-Market Sales Agreement [Member]
Cover [Abstract]
Measurement Input Type [Axis]
Construction allowance
Operating Lease Construction Allowance
Operating lease construction allowance.
Prepaid expenses and other assets
Prepaid Expense and Other Assets, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares, Cancelled/Forfeited
Number of Shares, Cancelled/Forfeited
Non-Convertible Term Loans [Member]
Non Convertible Term Loans [Member]
Non-convertible term loans.
Contractual Obligation Fiscal Year Maturity Schedule [Line Items]
Contractual Obligation Fiscal Year Maturity Schedule [Line Items]
Contractual obligation fiscal year maturity schedule.
Sale of Stock
Sale of Stock [Domain]
May twenty twenty three private placement.
May Twenty Twenty Three Private Placement [Member]
May 2023 Private Placement [Member]
Amortization of transaction costs
Amortization of Transaction Cost
Amortization of transaction cost.
General and Administrative Expense, Total
General and administrative
General and Administrative Expense
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Business Combination, Contingent Consideration, Liability, Noncurrent
Non-current contingent consideration [note 4 and note 5]
Subsequent Event [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Number of shares issued
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Short-Term Debt, Type [Domain]
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net
Intangible assets, Net Carrying Value
License agreement [note 3 and note 4]
Total
Conversion price
Conversion price per share
Debt Instrument, Convertible, Conversion Price
Warrants Issued in December 2020 [Member]
Warrants Issued In December Two Thousand Twenty [Member]
Warrants issued In December two thousand twenty.
Consolidated rent expense
Operating Lease, Expense
Gain (Loss) on Extinguishment of Debt, Total
Gain (Loss) on Extinguishment of Debt
Loss on extinguishment of 2023 SVB convertible term loan
Loss on extinguishment of 2023 SVB convertible term loan
Loss on extinguishment of 2023 SVB convertible term loan [note 6]
Loss on extinguishment of 2023 SVB convertible term loan [note 6]
Short-Term Debt, Type [Axis]
Dr. Slaoui.
Dr. Slaoui [Member]
Ownership [Axis]
Award vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Number of Securities Exercised Accompanying Warrants
Number of securities exercised accompanying warrants.
Number of securities exercised accompanying warrants
Contractual Obligation Fiscal Year Maturity Schedule [Table]
Contractual Obligation Fiscal Year Maturity Schedule [Table]
Contractual obligation fiscal year maturity schedule table.
Total unrecognized compensation expense related to the Company's restricted stock unit awards
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Stock trigger price
Debt Instrument, Convertible, Stock Price Trigger
Share purchase agreement.
Share Purchase Agreement [Member]
Share Purchase Agreement
Share Purchase Agreement [Member]
Operating lease, term of contract
Lessee, Operating Lease, Term of Contract
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, shares outstanding
Operating Lease, Liability, Current
Current portion of long-term obligations [note 9]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Summary of Contractual Obligations
Contractual Obligation, Fiscal Year Maturity [Table Text Block]
Two thousand twenty four silicon valley bank convertible debt.
Two Thousand Twenty Four Silicon Valley Bank Convertible Debt [Member]
2024 SVB Convertible Debt
Document Transition Report
Document Transition Report
Short-term investments [note 6]
Short-Term Investments
Research and Development Expense, Total
Research and development
Research and Development Expense
Research and development expense
Common Stock and Warrants Member
Common stock and warrants.
Common Stock and Warrants [Member]
Increase Decrease In Lease Obligations
Increase decrease in lease obligations.
Lease obligation [note 9]
Statement of Cash Flows [Abstract]
Expiration Date
Class Of Warrants Or Right Expiration Date
Class of warrants or right expiration date.
Monthly base rent, maximum annual increase
Monthly Base Rental Payments Maximum Annual Increase
Monthly base rental payments maximum annual increase.
Stock Issued During Period, Value, New Issues
Shares issued
Assets
Assets, Fair Value Disclosure [Abstract]
Sale of Stock, Additional Number of Shares to be Issued in Transaction
Sale of stock, additional number of shares to be issued in transaction.
Additional number of shares to be issued as option in part
Additional number of shares to be issued as option in part
Equity [Text Block]
Common Stock
Finite Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets [Line Items]
Beginning Balance, Shares
Ending Balance, Shares
Shares, Issued
Summary of Restricted Stock Unit Award Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Debt Agreement Period
Debt agreement period
Debt Agreement Period
Sale of stock, gross proceeds
Sale of Stock, Consideration Received Per Transaction
Net loss
Net loss
Convertible Debt [Abstract]
Convertible Term Loan Information
Debt Instrument, Covenant Compliance
Covenant compliance
Warrants and Rights Outstanding, Term
Warrants term
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Contractual Obligation, to be Paid, Year Two and Three, Total
1-3 years
Contractual Obligation, to be Paid, Year Two and Three
Other Address
Other Address [Member]
Operating cash flows to operating leases
Operating Lease, Payments
ASSETS
Assets [Abstract]
Risk-free interest rates
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Related party transaction expenses expected to incur
Related party transaction expenses expected to incur.
Expenses expected to incur
Document Fiscal Year Focus
Document Fiscal Year Focus
Investing Activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense [note 6]
Research and development [Member]
Research and Development Expense [Member]
Gross proceeds from issuance of common stock
Gross Proceeds From Issuance Of Common Stock
Gross proceeds from issuance of common stock.
Finite-Lived Intangible Asset, Expected Amortization, Year One
2026
2027
Convertible debt
Convertible Debt, Carrying Value
Convertible Debt
Accrued clinical liabilities
Accrued Liabilities Clinical Current
Accrued liabilities clinical current.
Conversion price percentage of closing trading share price
Conversion Price Percentage Of Closing Trading Share Price
Conversion Price Percentage Of Closing Trading Share Price
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Two thousand twenty three silicon valley bank convertible debt.
Two Thousand Twenty Three Silicon Valley Bank Convertible Debt [Member]
2023 SVB Convertible Debt
Nature Of Business And Basis Of Presentation [LineItems]
Nature of business and basis of presentation.
Sale of Stock, Consideration Received on Transaction
Sale of stock, net proceeds
Loan amount drawn
Long-Term Line of Credit
Long-Term Line of Credit, Total
Debt Instrument
Debt Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Warrants Issued In February Two Thousand And Twenty Four.
Warrants Issued in February 2024 [Member]
Assets, Fair Value Disclosure, Total
Total assets
Assets, Fair Value Disclosure
Sale of Stock
Sale of Stock [Axis]
Prepayment fee percentage after second anniversary before maturity
Debt Prepayment Fee Percentage After Second Anniversary And Before Maturity
Debt prepayment fee percentage after second anniversary before maturity.
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by (used in) investing activities
November 2022 Private Placement [Member]
Private Placement [Member]
Private Placement
Title of 12(b) Security
Title of 12(b) Security
Monthly base rent
Monthly Base Rental Payments
Monthly base rental payments.
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Cancelled/Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Cancelled/Forfeited
Money market securities [Member]
Money market securities (cash equivalents) [Member]
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Related party
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Series A convertible preferred stock member.
Corporate bonds and commercial paper cash equivalents [Member]
Corporate Bonds And Commercial Paper Cash Equivalents Member
Corporate bonds and commercial paper cash equivalents.
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Class of Warrant or Right [Line Items]
Class of Warrant or Right [Line Items]
Adjustments to additional paid in capitals additional costs to financings charged to APIC, Shares.
Adjustments To Additional Paid In Capitals Additional Costs To Financings Charged To APIC, Shares
Financing costs, Shares
May 2023 Registered Direct Offering [Member]
May 2023 Registered Direct Offering [Member]
May 2023 registered direct offering
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Accrued clinical liabilities
Increase Decrease In Accrued Clinical Liabilities
Increase decrease in accrued clinical liabilities.
Number Of Days Option Granted To Purchase Additional Shares
Number of days option granted to purchase additional shares.
Number of days option granted to purchase additional shares
Weighted Average Exercise Price, Beginning Balance
Weighted Average Exercise Price, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Measurement Frequency
Measurement Frequency [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Trading Symbol
Trading Symbol
Schedule Of Finite Lived Intangible Assets [Table]
Intangible Asset, Finite-Lived [Table]
Schedule Of Money Market Securities Table Text Block
Schedule of money market securities table text block.
Schedule of Money Market Securities
Liabilities, Fair Value Adjustment
Common stock aggregate maximum offering amount
Common Stock Aggregate Maximum Offering Amount
Common stock aggregate maximum offering amount.
Related Party Transaction [Table]
Shares issued on exercise of warrants, Shares
Shares Issued On Exercise Of Warrants
Shares issued on exercise of warrants.
Subsequent Event Type [Axis]
Components of Intangible Assets
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Employee-related Liabilities, Current, Total
Accrued compensation
Employee-related Liabilities, Current
Financing Activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Expected life
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Fair Value, Measurements, Recurring [Member]
Fair Value, Recurring [Member]
Finite-Lived Intangible Assets, Amortization Expense, Maturity Schedule [Abstract]
Finite-Lived Intangible Assets, Amortization Expense, Maturity Schedule [Abstract]
Equity Components
Equity Components [Axis]
June 2025 Financing [Member]
June Twenty Twenty Five Financing [Member]
June 2025 financing [Member]
Nature Of Business And Basis Of Presentation [Table]
Nature of business and basis of presentation.
Nonoperating Income (Expense)
Total other income (expense)
Total other income
Equity Component
Equity Component [Domain]
Asset Class [Axis]
Asset Class
Goodwill and Intangible Assets Disclosure [Abstract]
Sale of Stock, Percentage of Ownership before Transaction
Sale of stock, permitted ownership percentage
Address Type [Domain]
Contractual Obligation, to be Paid, Year Four and Five, Total
3-5 years
Contractual Obligation, to be Paid, Year Four and Five
Exercisable Subject to Certain Ownership Limitations [Member]
Exercisable subject to certain ownership limitations.
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total
Restricted stock unit settlements
Restricted stock unit settlements, Shares
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Sweep account.
Sweep Account [Member]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Shares issued under employee share purchase plan, Shares
Award expiration period
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Depreciation, Depletion and Amortization, Nonproduction, Total
Depreciation, Depletion and Amortization, Nonproduction
Depreciation and amortization [note 3]
Preferred stock, shares designated
Preferred Stock Shares Designated
Preferred stock shares designated.
Statement of Comprehensive Income [Abstract]
Warrants Issued in April 2020 [Member]
Warrants Issued In April Two Thousand Twenty1 [Member]
Warrants issued in April two thousand twenty 1.
Maximum [Member]
Maximum [Member]
Maximum
Entity Addresses, Address Type [Axis]
Liabilities, Fair Value Disclosure
Total liabilities
Fair value of total financial liabilities
Fair value of total financial liabilities
Statistical Measurement
Statistical Measurement [Axis]
Confidentially Marketed Public Offering [Member]
Confidentially marketed public offering.
Confidentially Marketed Public Offering [Member]
Intangible assets, Accumulated Amortization
Finite-Lived Intangible Assets, Accumulated Amortization
Common Stock, Value, Issued
Common stock, $0.001 par value, 150,000,000 shares authorized, 53,240,988 issued and outstanding at March 31, 2026 and 53,233,988 issued and outstanding at December 31, 2025
Term loan maturity date
Loan agreement expiration date
Line of Credit Facility, Expiration Date
Working capital
Working capital
Working Capital Balance
The capital of a business which is used in its day-to-day trading operations, calculated as the current assets minus the current liabilities.
Sale of Stock, Potential Number of Shares to be Issued in Transaction
Sale of stock, potential number of shares to be issued in transaction.
Number of shares agreed to issue and sell
Operating lease, revised monthly base rent expenses
Operating Lease Revised Monthly Base Rent Expenses
Operating lease, revised monthly base rent expenses.
June Twenty Twenty Five Public Offering Exercise of Overallotment Option [Member]
June 2025 public offering exercise of overallotment option [Member]
June 2025 Public Offering Exercise of Overallotment Option [Member]
Placement Agent Fees and Other Expenses
Placement Agent Fees and Other Expenses [Member]
Placement agent fees and other expenses.
Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent
Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent, Total
Net unrealized gain on marketable securities
Net unrealized loss on marketable securities
Amortization of Debt Issuance Costs
Amortization of 2024 SVB convertible term loan transaction costs [note 6]
Estimated Future Amortization Expense Related to Intangible Assets
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Warrants Issued in April 2020 [Member]
Warrants Issued In April Two Thousand Twenty [Member]
Warrants issued in April two thousand twenty.
Shares issued on exercise of warrants
Shares Issued On Exercise Of Warrants Value
Shares issued on exercise of warrants value.
Summary of Other Information Related to Leases
Schedule Of Supplemental Cash Flows Information Related To Leases Table [Text Block]
Schedule of supplemental cash flows information related to leases.
Lease, security deposit payment two anniversary
Lease Security Deposit Year Two
Lease security deposit year two.
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Total operating expenses
Costs and Expenses
Finite-Lived Intangible Assets by Major Class
Finite-Lived Intangible Assets by Major Class [Axis]
Taxes paid related to net share settlement of equity awards
Payment, Tax Withholding, Share-Based Payment Arrangement
Taxes paid related to net share settlement of equity awards
Lender Name
Lender Name [Axis]
Repayment of 2023 SVB convertible term loan [note 6]
Repayments of Convertible Debt
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Cash, Cash Equivalent, and Investment [Table Text Block]
Summary of Cash Equivalents and Restricted Cash
Related Party Transaction [Line Items]
Employee Share Purchase Plan
Employee Stock [Member]
Prepayment fee percentage occurs after first anniversary but on or prior to the second anniversary
Debt Prepayment Fee Percentage Occurs After First Anniversary But On Or Prior To The Second Anniversary
Debt prepayment fee percentage occurs after first anniversary but on or prior to the second anniversary.
Entity Registrant Name
Entity Registrant Name
Convertible Debt
Debt Disclosure [Text Block]
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Losses
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax, Total
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Finite-Lived Intangible Asset, Expected Amortization, Year Two
2027
2028
Other Nonoperating Income (Expense), Total
Other Nonoperating Income (Expense)
Other (expenses) income
Subsequent Events [Abstract]
Finite-Lived Intangible Asset, Expected Amortization, Year Three
2028
2029
Measurement Frequency
Measurement Frequency [Axis]
Proceeds from issuance of common stock
Proceeds from the May 2021 public offering, net of issuance costs
Estimated placement agent fees and other expenses
Finite lived intangible assets amortization expense after year three.
Finite Lived Intangible Assets Amortization Expense After Year Three
Thereafter
EXPENSES
Costs and Expenses [Abstract]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Liability Class [Axis]
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income
Accumulated Other Comprehensive Income (Loss), Net of Tax
Schedule of Aggregate Fair Value of Principal Amount of Convertible Debt
Convertible Debt [Table Text Block]
Purchase of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Number of Shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
February 2024 private placement.
February 2024 Private Placement [Member]
Total assets
Assets
Underwriting Member
Underwriting.
Underwriting [Member]
Fair Value of Financial Instruments
Fair Value of Financial Instruments, Policy [Policy Text Block]
Subscription Agreements Executed In November Two Thousand Twenty Two [Member]
Subscription Agreements Executed In November Two Thousand Twenty Two [Member]
Subscription Agreements Executed In November Two Thousand Twenty Two.
Sale of Stock, Number of Shares Issued in Transaction
Number of shares sold and issued
Common stock, shares issued
Shares issued, Shares
Stock Issued During Period, Shares, New Issues
Number of Shares, Released
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Diluted net loss per common share [note 7[d]]
Accounts payable
Increase (Decrease) in Accounts Payable, Trade
Title of Individual
Title and Position [Domain]
City Area Code
City Area Code
Schedule of changes in fair value of liabilities.
Schedule of Changes in Fair Value of Liabilities [Table Text Block]
Schedule of Changes in Fair Value of Liabilities
2024 Equity Inducement Plan [Member]
Two Thousand Twenty Four Equity Incentive Plan [Member]
Two thousand twenty four equity incentive plan.
Annual rent expense
Payments for Rent
Other Comprehensive Income (Loss), Net of Tax
Other comprehensive income
Total other comprehensive income
Total other comprehensive loss
Other comprehensive income (loss)
License Agreements [Member]
Licensing Agreements [Member]
Convertible debt principal amount
Convertible Debt, Principal Amount
Debt Instrument, Face Amount
Counterparty Name
Counterparty Name [Domain]
Commercial Paper Marketable Securities [Member]
Commercial paper marketable securities.
Commercial paper (marketable securities)
Convertible Debt, Noncurrent
Non-current portion of convertible debt [note 5 and note 6]
Number of Days Prior Notice to Increase or Decrease Ownership Limitation on Warrants
Number of days prior notice to increase or decrease ownership limitation on warrants.
Number of days prior notice to increase or decrease ownership limitation on warrants
Stock Issued During Period, Value, Employee Stock Purchase Plan
Shares issued under employee share purchase plan
Weighted Average Remaining Lease Term Operating leases
Operating Lease, Weighted Average Remaining Lease Term
SVB and Lender [Member]
Silicon Valley Bank And Lender [Member]
Silicon Valley Bank And Lender [Member]
Warrants Issued in April 2020 [Member]
Warrants Issued In April Two Thousand Twenty2 [Member]
Warrants issued in April two thousand twenty 2.
Initial term of lease expiration date
Lease Expiration Date
Restricted stock unit settlements
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures, Total
Impairment of intangible assets
Impairment of Intangible Assets, Finite-Lived
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash, cash equivalents and restricted cash at beginning of the period
Cash, cash equivalents and restricted cash at end of the period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Corporate Bonds [Member]
Corporate Bond Securities [Member]
Accretion of discount on modification of debt.
Accretion Of Discount On Modification Of Debt
Accrued interest on 2023 SVB convertible term loan [note 6]
Accumulated deficit [Member]
Retained Earnings [Member]
Entity Address, Country
Entity Address, Country
Cash and Cash Equivalents [Axis]
February Twenty Twenty Four Direct Offering [Member]
February 2024 Direct Offering [Member]
February 2024 Direct Offering [Member]
Share-Based Payment Arrangement, Noncash Expense, Total
Total stock-based compensation
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation [note 7[c], note 7[e] and note 7[f]]
Payments of Stock Issuance Costs
Placement agent fees and offering expenses
Government Grant
Government Grants [Text Block]
Government grants.
Weighted Average Discount Rate Operating leases
Operating Lease, Weighted Average Discount Rate, Percent
Operating Lease, Liability, Noncurrent
Long-term obligations [note 9]
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Proceeds from issuance of registered direct offering.
Proceeds from Issuance of Registered Direct Offering
Proceeds from registered direct offering, net of issuance costs
Custodian deposits.
Custodian Deposits
Custodian deposits
Summary of Outstanding Warrants
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Nonoperating Income (Expense) [Abstract]
OTHER INCOME
Convertible Term Loan [Member]
Convertible term loan.
Convertible Term Loan [Member]
Entity Interactive Data Current
Entity Interactive Data Current
Income Statement Location
Statement of Income Location, Balance [Domain]
Stock issued during period value restricted stock unit settlement withheld and retired to treasury.
Stock Issued During Period Value Restricted Stock Unit Settlement Withheld And Retired To Treasury
Restricted stock unit settlements withheld and retired to treasury
Operating Activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Vancouver, British Columbia [Member]
BRITISH COLUMBIA
Cash equivalents
Cash Equivalents, at Carrying Value, Total
Cash equivalents, amortized cost and estimated fair value
Cash Equivalents, at Carrying Value
Entity Tax Identification Number
Entity Tax Identification Number
Prepaid Expenses Related Party
Prepaid expenses related party.
Prepayment of expenses
Long-Term Debt, Type
Long-Term Debt, Type [Axis]
SVB convertible debt refinancing discount
Adjustment to Additional Paid in Capital Convertible Debt Refinancing Discount
Adjustment to additional paid in capital convertible debt refinancing discount.
Number of development agreements
Number of development agreements.
Summary of Stock Options Activity
Schedule of Stock Options Roll Forward [Table Text Block]
Warrant Ownership Change Notice Period Term
Warrant ownership change notice period term.
Warrant ownership change notice period term
Local Phone Number
Local Phone Number
Threshold percentage of conversion amount of debt
Debt Instrument Convertible Threshold Percentage Of Conversion Amount Of Debt
Debt instrument convertible threshold percentage of conversion amount of debt.
Prime Rate Minus 1.0% [Member]
Prime Rate Minus One Percentage [Member]
Prime rate minus one percentage.
Unrecognized compensation expense related to stock options granted
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
New Employee Inducement Grants [Member]
New Employee Inducement Grants [Member]
New employee inducement grants.
Accounting Policies [Abstract]
Additional Number of Securities Underwriters Exercised by Warrants or Rights
Additional Number of Securities Underwriters Exercised by Warrants or Rights
Additional number of securities underwriters exercised by warrants or rights in part
Class of Stock
Class of Stock [Domain]
Debt conversion description
Debt Conversion, Description
Commercial Paper [Member]
Commercial Paper [Member]
Common shares reserved for issuance under incentive plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Weighted-average period, restricted stock awards
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Cash,cash equivalents and short-term investments
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Warrants Issued in December 2019 [Member]
Warrants Issued In December Two Thousand Nineteen [Member]
Warrants issued in december two thousand nineteen.
Average Maturity Period Of Cash Equivalents and Marketable Securities
Average maturity period of cash equivalents and marketable securities.
Average maturity period of cash equivalents and marketable securities
Less than 1 year
Contractual Obligation, to be Paid, Year One
Entity Emerging Growth Company
Entity Emerging Growth Company