3.26.1 html 242 344 1 false 88 0 false 12 false false R1.htm 995200090 - Document - Document And Entity Information Sheet http://orchestrabiomed.com/role/DocumentDocumentAndEntityInformation Document And Entity Information Cover 1 false false R2.htm 995200100 - Statement - Condensed Consolidated Balance Sheets Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedBalanceSheets Condensed Consolidated Balance Sheets Statements 2 false false R3.htm 995200105 - Statement - Condensed Consolidated Balance Sheets (Parentheticals) Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedBalanceSheetsParentheticals Condensed Consolidated Balance Sheets (Parentheticals) Statements 3 false false R4.htm 995200200 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedStatementsOfOperationsAndComprehensiveLoss Condensed Consolidated Statements of Operations and Comprehensive Loss Statements 4 false false R5.htm 995200300 - Statement - Condensed Consolidated Statements of Stockholders' Equity Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedStatementsOfStockholdersEquity Condensed Consolidated Statements of Stockholders' Equity Statements 5 false false R6.htm 995200305 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Parenthetical) Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedStatementsOfStockholdersEquityParenthetical Condensed Consolidated Statements of Stockholders' Equity (Parenthetical) Statements 6 false false R7.htm 995200400 - Statement - Condensed Consolidated Statements of Cash Flows Sheet http://orchestrabiomed.com/role/StatementCondensedConsolidatedStatementsOfCashFlows Condensed Consolidated Statements of Cash Flows Statements 7 false false R8.htm 995210101 - Disclosure - Organization and Basis of Presentation Sheet http://orchestrabiomed.com/role/DisclosureOrganizationAndBasisOfPresentation Organization and Basis of Presentation Notes 8 false false R9.htm 995210201 - Disclosure - Summary of Significant Accounting Policies Sheet http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPolicies Summary of Significant Accounting Policies Notes 9 false false R10.htm 995210301 - Disclosure - Medtronic Agreement Sheet http://orchestrabiomed.com/role/DisclosureMedtronicAgreement Medtronic Agreement Notes 10 false false R11.htm 995210401 - Disclosure - Financial Instruments and Fair Value Measurements Sheet http://orchestrabiomed.com/role/DisclosureFinancialInstrumentsAndFairValueMeasurements Financial Instruments and Fair Value Measurements Notes 11 false false R12.htm 995210501 - Disclosure - Marketable Securities and Strategic Investments Sheet http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestments Marketable Securities and Strategic Investments Notes 12 false false R13.htm 995210601 - Disclosure - Balance Sheet Components Sheet http://orchestrabiomed.com/role/DisclosureBalanceSheetComponents Balance Sheet Components Notes 13 false false R14.htm 995210701 - Disclosure - Common and Preferred Stock Sheet http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStock Common and Preferred Stock Notes 14 false false R15.htm 995210801 - Disclosure - Derivative Liability Sheet http://orchestrabiomed.com/role/DisclosureDerivativeLiability Derivative Liability Notes 15 false false R16.htm 995210901 - Disclosure - Warrants Sheet http://orchestrabiomed.com/role/DisclosureWarrants Warrants Notes 16 false false R17.htm 995211001 - Disclosure - Stock-Based Compensation Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensation Stock-Based Compensation Notes 17 false false R18.htm 995211101 - Disclosure - Leases Sheet http://orchestrabiomed.com/role/DisclosureLeases Leases Notes 18 false false R19.htm 995211201 - Disclosure - Related Party Transactions Sheet http://orchestrabiomed.com/role/DisclosureRelatedPartyTransactions Related Party Transactions Notes 19 false false R20.htm 995211301 - Disclosure - Royalty Purchase Agreement Sheet http://orchestrabiomed.com/role/DisclosureRoyaltyPurchaseAgreement Royalty Purchase Agreement Notes 20 false false R21.htm 995211401 - Disclosure - Debt Financing Sheet http://orchestrabiomed.com/role/DisclosureDebtFinancing Debt Financing Notes 21 false false R22.htm 995211501 - Disclosure - Segment Disclosures Sheet http://orchestrabiomed.com/role/DisclosureSegmentDisclosures Segment Disclosures Notes 22 false false R23.htm 995211601 - Disclosure - Net Loss Per Share Sheet http://orchestrabiomed.com/role/DisclosureNetLossPerShare Net Loss Per Share Notes 23 false false R24.htm 995410 - Disclosure - Pay vs Performance Disclosure Sheet http://xbrl.sec.gov/ecd/role/PvpDisclosure Pay vs Performance Disclosure Notes 24 false false R25.htm 995445 - Disclosure - Insider Trading Arrangements Sheet http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements Insider Trading Arrangements Notes 25 false false R26.htm 99920202 - Disclosure - Summary of Significant Accounting Policies (Policies) Sheet http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPoliciesPolicies Summary of Significant Accounting Policies (Policies) Policies http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPolicies 26 false false R27.htm 99930203 - Disclosure - Summary of Significant Accounting Policies (Tables) Sheet http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPoliciesTables Summary of Significant Accounting Policies (Tables) Tables http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPolicies 27 false false R28.htm 99930403 - Disclosure - Financial Instruments and Fair Value Measurements (Tables) Sheet http://orchestrabiomed.com/role/DisclosureFinancialInstrumentsAndFairValueMeasurementsTables Financial Instruments and Fair Value Measurements (Tables) Tables http://orchestrabiomed.com/role/DisclosureFinancialInstrumentsAndFairValueMeasurements 28 false false R29.htm 99930503 - Disclosure - Marketable Securities and Strategic Investments (Tables) Sheet http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestmentsTables Marketable Securities and Strategic Investments (Tables) Tables http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestments 29 false false R30.htm 99930603 - Disclosure - Balance Sheet Components (Tables) Sheet http://orchestrabiomed.com/role/DisclosureBalanceSheetComponentsTables Balance Sheet Components (Tables) Tables http://orchestrabiomed.com/role/DisclosureBalanceSheetComponents 30 false false R31.htm 99930703 - Disclosure - Common and Preferred Stock (Tables) Sheet http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStockTables Common and Preferred Stock (Tables) Tables http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStock 31 false false R32.htm 99930803 - Disclosure - Derivative Liability (Tables) Sheet http://orchestrabiomed.com/role/DisclosureDerivativeLiabilityTables Derivative Liability (Tables) Tables http://orchestrabiomed.com/role/DisclosureDerivativeLiability 32 false false R33.htm 99930903 - Disclosure - Warrants (Tables) Sheet http://orchestrabiomed.com/role/DisclosureWarrantsTables Warrants (Tables) Tables http://orchestrabiomed.com/role/DisclosureWarrants 33 false false R34.htm 99931003 - Disclosure - Stock-Based Compensation (Tables) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationTables Stock-Based Compensation (Tables) Tables http://orchestrabiomed.com/role/DisclosureStockBasedCompensation 34 false false R35.htm 99931103 - Disclosure - Leases (Tables) Sheet http://orchestrabiomed.com/role/DisclosureLeasesTables Leases (Tables) Tables http://orchestrabiomed.com/role/DisclosureLeases 35 false false R36.htm 99931303 - Disclosure - Royalty Purchase Agreement (Tables) Sheet http://orchestrabiomed.com/role/DisclosureRoyaltyPurchaseAgreementTables Royalty Purchase Agreement (Tables) Tables http://orchestrabiomed.com/role/DisclosureRoyaltyPurchaseAgreement 36 false false R37.htm 99931403 - Disclosure - Debt Financing (Tables) Sheet http://orchestrabiomed.com/role/DisclosureDebtFinancingTables Debt Financing (Tables) Tables http://orchestrabiomed.com/role/DisclosureDebtFinancing 37 false false R38.htm 99931503 - Disclosure - Segment Disclosures (Tables) Sheet http://orchestrabiomed.com/role/DisclosureSegmentDisclosuresTables Segment Disclosures (Tables) Tables http://orchestrabiomed.com/role/DisclosureSegmentDisclosures 38 false false R39.htm 99931603 - Disclosure - Net Loss Per Share (Tables) Sheet http://orchestrabiomed.com/role/DisclosureNetLossPerShareTables Net Loss Per Share (Tables) Tables http://orchestrabiomed.com/role/DisclosureNetLossPerShare 39 false false R40.htm 99940101 - Disclosure - Organization and Basis of Presentation (Details) Sheet http://orchestrabiomed.com/role/DisclosureOrganizationAndBasisOfPresentationDetails Organization and Basis of Presentation (Details) Details http://orchestrabiomed.com/role/DisclosureOrganizationAndBasisOfPresentation 40 false false R41.htm 99940201 - Disclosure - Summary of Significant Accounting Policies - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPoliciesOtherDetails Summary of Significant Accounting Policies - Other (Details) Details http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPoliciesTables 41 false false R42.htm 99940202 - Disclosure - Summary of Significant Accounting Policies - Schedule of property and equipment (Details) Sheet http://orchestrabiomed.com/role/DisclosureSummaryOfSignificantAccountingPoliciesScheduleOfPropertyAndEquipmentDetails Summary of Significant Accounting Policies - Schedule of property and equipment (Details) Details 42 false false R43.htm 99940301 - Disclosure - Medtronic Agreement (Details) Sheet http://orchestrabiomed.com/role/DisclosureMedtronicAgreementDetails Medtronic Agreement (Details) Details http://orchestrabiomed.com/role/DisclosureMedtronicAgreement 43 false false R44.htm 99940401 - Disclosure - Financial Instruments and Fair Value Measurements - Schedule of financial assets and liabilities measured at fair value (Details) Sheet http://orchestrabiomed.com/role/DisclosureFinancialInstrumentsAndFairValueMeasurementsScheduleOfFinancialAssetsAndLiabilitiesMeasuredAtFairValueDetails Financial Instruments and Fair Value Measurements - Schedule of financial assets and liabilities measured at fair value (Details) Details 44 false false R45.htm 99940501 - Disclosure - Marketable Securities and Strategic Investments - Schedule of marketable securities (Details) Sheet http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestmentsScheduleOfMarketableSecuritiesDetails Marketable Securities and Strategic Investments - Schedule of marketable securities (Details) Details 45 false false R46.htm 99940502 - Disclosure - Marketable Securities and Strategic Investments - (Other Information) (Details) Sheet http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestmentsOtherInformationDetails Marketable Securities and Strategic Investments - (Other Information) (Details) Details http://orchestrabiomed.com/role/DisclosureMarketableSecuritiesAndStrategicInvestmentsTables 46 false false R47.htm 99940601 - Disclosure - Balance Sheet Components - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureBalanceSheetComponentsOtherDetails Balance Sheet Components - Other (Details) Details 47 false false R48.htm 99940602 - Disclosure - Balance Sheet Components - Schedule of property and equipment, net (Details) Sheet http://orchestrabiomed.com/role/DisclosureBalanceSheetComponentsScheduleOfPropertyAndEquipmentNetDetails Balance Sheet Components - Schedule of property and equipment, net (Details) Details 48 false false R49.htm 99940603 - Disclosure - Balance Sheet Components - Schedule of accrued expenses and other liabilities (Details) Sheet http://orchestrabiomed.com/role/DisclosureBalanceSheetComponentsScheduleOfAccruedExpensesAndOtherLiabilitiesDetails Balance Sheet Components - Schedule of accrued expenses and other liabilities (Details) Details 49 false false R50.htm 99940701 - Disclosure - Common and Preferred Stock - Other Information (Details) Sheet http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStockOtherInformationDetails Common and Preferred Stock - Other Information (Details) Details 50 false false R51.htm 99940702 - Disclosure - Common and Preferred Stock - Schedule of roll-forward of the Series A Preferred Stock activity (Details) Sheet http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStockScheduleOfRollForwardOfSeriesPreferredStockActivityDetails Common and Preferred Stock - Schedule of roll-forward of the Series A Preferred Stock activity (Details) Details 51 false false R52.htm 99940703 - Disclosure - Common and Preferred Stock - At-the-Market Offering and Shelf Registration Statement (Details) Sheet http://orchestrabiomed.com/role/DisclosureCommonAndPreferredStockAtMarketOfferingAndShelfRegistrationStatementDetails Common and Preferred Stock - At-the-Market Offering and Shelf Registration Statement (Details) Details 52 false false R53.htm 99940801 - Disclosure - Derivative Liability - Reconciliation of the derivative liability associated with the series A preferred stock (Details) Sheet http://orchestrabiomed.com/role/DisclosureDerivativeLiabilityReconciliationOfDerivativeLiabilityAssociatedWithSeriesPreferredStockDetails Derivative Liability - Reconciliation of the derivative liability associated with the series A preferred stock (Details) Details 53 false false R54.htm 99940802 - Disclosure - Derivative Liability - Assumptions for derivative components (Details) Sheet http://orchestrabiomed.com/role/DisclosureDerivativeLiabilityAssumptionsForDerivativeComponentsDetails Derivative Liability - Assumptions for derivative components (Details) Details 54 false false R55.htm 99940901 - Disclosure - Warrants - Summarized Outstanding Warrants (Details) Sheet http://orchestrabiomed.com/role/DisclosureWarrantsSummarizedOutstandingWarrantsDetails Warrants - Summarized Outstanding Warrants (Details) Details 55 false false R56.htm 99941001 - Disclosure - Stock-Based Compensation - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationOtherDetails Stock-Based Compensation - Other (Details) Details 56 false false R57.htm 99941002 - Disclosure - Stock-Based Compensation - Schedule of cost related to stock-based compensation (Details) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationScheduleOfCostRelatedToStockBasedCompensationDetails Stock-Based Compensation - Schedule of cost related to stock-based compensation (Details) Details 57 false false R58.htm 99941003 - Disclosure - Stock-Based Compensation - Schedule of stock option activity (Details) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationScheduleOfStockOptionActivityDetails Stock-Based Compensation - Schedule of stock option activity (Details) Details 58 false false R59.htm 99941004 - Disclosure - Stock-Based Compensation - Schedule of restricted stock activity (Details) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationScheduleOfRestrictedStockActivityDetails Stock-Based Compensation - Schedule of restricted stock activity (Details) Details 59 false false R60.htm 99941005 - Disclosure - Stock-Based Compensation - Schedule of estimated grant-date fair value calculated using Black-Scholes option pricing model (Details) Sheet http://orchestrabiomed.com/role/DisclosureStockBasedCompensationScheduleOfEstimatedGrantDateFairValueCalculatedUsingBlackScholesOptionPricingModelDetails Stock-Based Compensation - Schedule of estimated grant-date fair value calculated using Black-Scholes option pricing model (Details) Details 60 false false R61.htm 99941101 - Disclosure - Leases - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureLeasesOtherDetails Leases - Other (Details) Details 61 false false R62.htm 99941102 - Disclosure - Leases - Schedule of recognized as an asset and operating lease liabilities (Details) Sheet http://orchestrabiomed.com/role/DisclosureLeasesScheduleOfRecognizedAsAssetAndOperatingLeaseLiabilitiesDetails Leases - Schedule of recognized as an asset and operating lease liabilities (Details) Details 62 false false R63.htm 99941103 - Disclosure - Leases - Components of lease expense (Details) Sheet http://orchestrabiomed.com/role/DisclosureLeasesComponentsOfLeaseExpenseDetails Leases - Components of lease expense (Details) Details 63 false false R64.htm 99941104 - Disclosure - Leases - Schedule of future minimum rental payments, exclusive of taxes, insurance and other costs, under the leases (Details) Sheet http://orchestrabiomed.com/role/DisclosureLeasesScheduleOfFutureMinimumRentalPaymentsExclusiveOfTaxesInsuranceAndOtherCostsUnderLeasesDetails Leases - Schedule of future minimum rental payments, exclusive of taxes, insurance and other costs, under the leases (Details) Details 64 false false R65.htm 99941201 - Disclosure - Related Party Transactions (Details) Sheet http://orchestrabiomed.com/role/DisclosureRelatedPartyTransactionsDetails Related Party Transactions (Details) Details http://orchestrabiomed.com/role/DisclosureRelatedPartyTransactions 65 false false R66.htm 99941301 - Disclosure - Royalty Purchase Agreement - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureRoyaltyPurchaseAgreementOtherDetails Royalty Purchase Agreement - Other (Details) Details 66 false false R67.htm 99941302 - Disclosure - Royalty Purchase Agreement - Activity of the Revenue purchase agreement (Details) Sheet http://orchestrabiomed.com/role/DisclosureRoyaltyPurchaseAgreementActivityOfRevenuePurchaseAgreementDetails Royalty Purchase Agreement - Activity of the Revenue purchase agreement (Details) Details 67 false false R68.htm 99941401 - Disclosure - Debt Financing - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureDebtFinancingOtherDetails Debt Financing - Other (Details) Details 68 false false R69.htm 99941402 - Disclosure - Debt Financing - Schedule of amount of principal payments (Details) Sheet http://orchestrabiomed.com/role/DisclosureDebtFinancingScheduleOfAmountOfPrincipalPaymentsDetails Debt Financing - Schedule of amount of principal payments (Details) Details 69 false false R70.htm 99941501 - Disclosure - Segment Disclosures (Details) Sheet http://orchestrabiomed.com/role/DisclosureSegmentDisclosuresDetails Segment Disclosures (Details) Details http://orchestrabiomed.com/role/DisclosureSegmentDisclosuresTables 70 false false R71.htm 99941601 - Disclosure - Net Loss Per Share - Other (Details) Sheet http://orchestrabiomed.com/role/DisclosureNetLossPerShareOtherDetails Net Loss Per Share - Other (Details) Details 71 false false R72.htm 99941602 - Disclosure - Net Loss Per Share - Schedule of calculation of diluted net loss per share (Details) Sheet http://orchestrabiomed.com/role/DisclosureNetLossPerShareScheduleOfCalculationOfDilutedNetLossPerShareDetails Net Loss Per Share - Schedule of calculation of diluted net loss per share (Details) Details 72 false false All Reports Book All Reports obio-20260331.xsd obio-20260331_cal.xml obio-20260331_def.xml obio-20260331_lab.xml obio-20260331_pre.xml obio-20260331x10q.htm obio-20260331x10q001.jpg http://fasb.org/us-gaap/2025 http://xbrl.sec.gov/dei/2025 http://xbrl.sec.gov/ecd/2025 true true