3.26.1 html 140 239 1 false 51 0 false 5 false false R1.htm 75000 - Document - Document and Entity Information Sheet http://metagenomi.co/20260331/taxonomy/role/DocumentDocumentAndEntityInformation Document and Entity Information Cover 1 false false R2.htm 75010 - Statement - Condensed Balance Sheets Sheet http://metagenomi.co/20260331/taxonomy/role/StatementCondensedBalanceSheets Condensed Balance Sheets Statements 2 false false R3.htm 75020 - Statement - Condensed Balance Sheets (Parenthetical) Sheet http://metagenomi.co/20260331/taxonomy/role/StatementCondensedBalanceSheetsParenthetical Condensed Balance Sheets (Parenthetical) Statements 3 false false R4.htm 75030 - Statement - Condensed Statements of Operations and Comprehensive Loss Sheet http://metagenomi.co/20260331/taxonomy/role/StatementCondensedStatementsOfOperationsAndComprehensiveLoss Condensed Statements of Operations and Comprehensive Loss Statements 4 false false R5.htm 75040 - Statement - Condensed Statements of Stockholders' Equity Sheet http://metagenomi.co/20260331/taxonomy/role/StatementCondensedStatementsOfStockholdersEquity Condensed Statements of Stockholders' Equity Statements 5 false false R6.htm 75050 - Statement - Condensed Statements of Cash Flows Sheet http://metagenomi.co/20260331/taxonomy/role/StatementCondensedStatementsOfCashFlows Condensed Statements of Cash Flows Statements 6 false false R7.htm 995410 - Disclosure - Pay vs Performance Disclosure Sheet http://xbrl.sec.gov/ecd/role/PvpDisclosure Pay vs Performance Disclosure Notes 7 false false R8.htm 995445 - Disclosure - Insider Trading Arrangements Sheet http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements Insider Trading Arrangements Notes 8 false false R9.htm 995455 - Disclosure - Description of Business, Organization and Liquidity Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureDescriptionOfBusinessOrganizationAndLiquidity Description of Business, Organization and Liquidity Notes 9 false false R10.htm 995465 - Disclosure - Summary of Significant Accounting Policies Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSummaryOfSignificantAccountingPolicies Summary of Significant Accounting Policies Notes 10 false false R11.htm 995475 - Disclosure - Fair Value Measurements Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureFairValueMeasurements Fair Value Measurements Notes 11 false false R12.htm 995485 - Disclosure - Marketable Securities Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecurities Marketable Securities Notes 12 false false R13.htm 995495 - Disclosure - Long-Term Investments Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureLongtermInvestments Long-Term Investments Notes 13 false false R14.htm 995505 - Disclosure - Accrued Expenses and Other Current Liabilities Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilities Accrued Expenses and Other Current Liabilities Notes 14 false false R15.htm 995515 - Disclosure - Significant Agreements Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSignificantAgreements Significant Agreements Notes 15 false false R16.htm 995525 - Disclosure - Commitments and Contingencies Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureCommitmentsAndContingencies Commitments and Contingencies Notes 16 false false R17.htm 995535 - Disclosure - Common Stock Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureCommonStock Common Stock Notes 17 false false R18.htm 995545 - Disclosure - Stock-Based Compensation Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensation Stock-Based Compensation Notes 18 false false R19.htm 995555 - Disclosure - Segment Information Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSegmentInformation Segment Information Notes 19 false false R20.htm 995565 - Disclosure - Net Loss Per Share Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureNetLossPerShare Net Loss Per Share Notes 20 false false R21.htm 995585 - Disclosure - Summary of Significant Accounting Policies (Policies) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSummaryOfSignificantAccountingPoliciesPolicies Summary of Significant Accounting Policies (Policies) Policies http://metagenomi.co/20260331/taxonomy/role/DisclosureSummaryOfSignificantAccountingPolicies 21 false false R22.htm 995595 - Disclosure - Fair Value Measurements (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureFairValueMeasurementsTables Fair Value Measurements (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureFairValueMeasurements 22 false false R23.htm 995605 - Disclosure - Marketable Securities (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecuritiesTables Marketable Securities (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecurities 23 false false R24.htm 995615 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilitiesTables Accrued Expenses and Other Current Liabilities (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilities 24 false false R25.htm 995625 - Disclosure - Stock-Based Compensation (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationTables Stock-Based Compensation (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensation 25 false false R26.htm 995635 - Disclosure - Segment Information (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSegmentInformationTables Segment Information (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureSegmentInformation 26 false false R27.htm 995645 - Disclosure - Net Loss Per Share (Tables) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureNetLossPerShareTables Net Loss Per Share (Tables) Tables http://metagenomi.co/20260331/taxonomy/role/DisclosureNetLossPerShare 27 false false R28.htm 995655 - Disclosure - Description of Business, Organization and Liquidity - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureDescriptionOfBusinessOrganizationAndLiquidityAdditionalInformationDetails Description of Business, Organization and Liquidity - Additional Information (Details) Details 28 false false R29.htm 995665 - Disclosure - Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureFairValueMeasurementsSummaryOfFinancialAssetsMeasuredAtFairValueOnRecurringBasisDetails Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details) Details 29 false false R30.htm 995675 - Disclosure - Fair Value Measurements - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureFairValueMeasurementsAdditionalInformationDetails Fair Value Measurements - Additional Information (Details) Details 30 false false R31.htm 995695 - Disclosure - Marketable Securities - Summary of Amortized Cost, Unrealized Gains (Losses) and Fair Value of Available-for-sale Marketable Securities (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecuritiesSummaryOfAmortizedCostUnrealizedGainsLossesAndFairValueOfAvailableforsaleMarketableSecuritiesDetails Marketable Securities - Summary of Amortized Cost, Unrealized Gains (Losses) and Fair Value of Available-for-sale Marketable Securities (Details) Details 31 false false R32.htm 995705 - Disclosure - Marketable Securities - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecuritiesAdditionalInformationDetails Marketable Securities - Additional Information (Details) Details 32 false false R33.htm 995715 - Disclosure - Marketable Securities - Summary of Amortized Cost and Fair Value of Available-for-sale Marketable Securities by Contractual Maturity (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureMarketableSecuritiesSummaryOfAmortizedCostAndFairValueOfAvailableforsaleMarketableSecuritiesByContractualMaturityDetails Marketable Securities - Summary of Amortized Cost and Fair Value of Available-for-sale Marketable Securities by Contractual Maturity (Details) Details 33 false false R34.htm 995725 - Disclosure - Long-Term Investments - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureLongtermInvestmentsAdditionalInformationDetails Long-Term Investments - Additional Information (Details) Details 34 false false R35.htm 995735 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilitiesScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesDetails Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) Details 35 false false R36.htm 995745 - Disclosure - Significant Agreements - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSignificantAgreementsAdditionalInformationDetails Significant Agreements - Additional Information (Details) Details 36 false false R37.htm 995755 - Disclosure - Significant Agreements - Additional Information (Details1) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSignificantAgreementsAdditionalInformationDetails1 Significant Agreements - Additional Information (Details1) Details 37 false false R38.htm 995765 - Disclosure - Common Stock - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureCommonStockAdditionalInformationDetails Common Stock - Additional Information (Details) Details 38 false false R39.htm 995775 - Disclosure - Stock-Based Compensation - Addition Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationAdditionInformationDetails Stock-Based Compensation - Addition Information (Details) Details 39 false false R40.htm 995785 - Disclosure - Stock-Based Compensation - Summary of Unvested Common Stock Activity (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationSummaryOfUnvestedCommonStockActivityDetails Stock-Based Compensation - Summary of Unvested Common Stock Activity (Details) Details 40 false false R41.htm 995805 - Disclosure - Stock-Based Compensation - Summary of Common Stock Option Activity (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationSummaryOfCommonStockOptionActivityDetails Stock-Based Compensation - Summary of Common Stock Option Activity (Details) Details 41 false false R42.htm 995815 - Disclosure - Stock-Based Compensation - Summary of Common Restricted Stock Unit Activity (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationSummaryOfCommonRestrictedStockUnitActivityDetails Stock-Based Compensation - Summary of Common Restricted Stock Unit Activity (Details) Details 42 false false R43.htm 995825 - Disclosure - Stock-based Compensation - Summary of Classification of Stock-based Compensation Expense (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureStockbasedCompensationSummaryOfClassificationOfStockbasedCompensationExpenseDetails Stock-based Compensation - Summary of Classification of Stock-based Compensation Expense (Details) Details 43 false false R44.htm 995835 - Disclosure - Segment Information - Additional Information (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSegmentInformationAdditionalInformationDetails Segment Information - Additional Information (Details) Details 44 false false R45.htm 995845 - Disclosure - Segment Information - Summary of Results of Operations Provided to Company's CODM (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureSegmentInformationSummaryOfResultsOfOperationsProvidedToCompanysCodmDetails Segment Information - Summary of Results of Operations Provided to Company's CODM (Details) Details 45 false false R46.htm 995855 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share Attributable To Common Stockholders (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureNetLossPerShareScheduleOfBasicAndDilutedNetLossPerShareAttributableToCommonStockholdersDetails Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share Attributable To Common Stockholders (Details) Details 46 false false R47.htm 995865 - Disclosure - Net Loss Per Share - Summary of Outstanding Potentially Dilutive Securities that have been Excluded from Calculation of Diluted Net Loss Per Unit (Details) Sheet http://metagenomi.co/20260331/taxonomy/role/DisclosureNetLossPerShareSummaryOfOutstandingPotentiallyDilutiveSecuritiesThatHaveBeenExcludedFromCalculationOfDilutedNetLossPerUnitDet Net Loss Per Share - Summary of Outstanding Potentially Dilutive Securities that have been Excluded from Calculation of Diluted Net Loss Per Unit (Details) Details 47 false false All Reports Book All Reports mgx-20260331.htm mgx-20260331.xsd http://fasb.org/us-gaap/2025 http://xbrl.sec.gov/dei/2025 http://xbrl.sec.gov/ecd/2025 false false