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Warrants Associated With March 2026 Private Placement Sale of Stock Sale of Stock [Axis] Proceeds from employee stock purchase plan issuances Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash (used in) provided by investing activities Title of Each Class Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Long term restricted cash balance Restricted Cash Noncurrent Fair Value Disclosure Restricted cash noncurrent fair value disclosure. Forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Money market funds Money Market Funds [Member] Increase (decrease) in license agreement receivable Increase (Decrease) In License Agreement Receivable License agreement receivable Private Placement proceeds receivable (in shares) Private Placement Proceeds Receivable Private placement proceeds receivable. Preclinical Expense Preclinical expense. Preclinical expense Beginning balance - Outstanding (in dollars per share) Ending balance - Outstanding (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price March 2019 Notes Six Percent Convertible Senior Notes Due Two Thousand And Twenty Five [Member] Six percent convertible senior notes due two thousand and twenty five. Additional Paid-in Capital Additional Paid-in Capital [Member] Measurement Frequency Measurement Frequency [Domain] Income Statement Location Statement of Income Location, Balance [Axis] Trading Symbol Trading Symbol Subsequent Event Type [Axis] Poxel's Right, Title and Interest Poxels Right, Title and Interest [Member] Poxels Right, Title and Interest [Member] Cash flows from financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Fair Value, Recurring [Member] Fair Value, Measurements, Recurring Accrued Expenses Accounts Payable and Accrued Liabilities Disclosure [Text Block] Equity Components Equity Components [Axis] Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Summary of Investments Debt Securities, Held-to-Maturity [Table Text Block] Nonoperating Income (Expense), Total Nonoperating Income (Expense) Total other expense (income) Equity Component Equity Component [Domain] Deferred revenue, long term Deferred revenue Deferred Revenue, Noncurrent, Total Investments Investments Investments, Total Prepaid insurance Prepaid Insurance Common stock issued through employee stock purchase (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Accrued other rebates. 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Accrued Severance Accrued severance Deferred Costs, Current Deferred Costs, Current, Total Deferred offering costs Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Repayments of Convertible Debt Payment of convertible debt Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Registrant Name Entity Registrant Name Entity Registrant Name Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Additional Paid in Capital, Total Additional paid-in capital Additional Paid in Capital Subsequent Events [Abstract] Proceeds allocated for Shares issued in April 2026 Proceeds Allocated For Shares Issued Proceeds allocated for shares issued. Income tax expense Income Tax Expense (Benefit), Total Income tax (benefit) expense Income tax (benefit) expense Offering Costs for Private Placement Warrant Issuance Offering costs for private placement warrant issuance. 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Proceeds allocated for Pre-Funded Warrants Net (loss) income per share - diluted Earnings Per Share, Diluted, Total Earnings Per Share, Diluted Net loss per share - diluted Schedule of Drug Development Segment and Reconciliation to Consolidated Net (Loss) Income Segment Operations Schedule of Segment Reporting Information, by Segment [Table Text Block] Ownership Rights Percentage Ownership Rights Percentage Owns percentage of right Asset Acquisition [Axis] City Area Code City Area Code Total principal and final fee payment Face amount Debt Instrument, Face Amount Counterparty Name [Domain] Common stock issued through employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Segment Reporting Information [Line Items] Common stock issued for vested restricted stock units (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Gross Common stock issued for restricted stock units (in shares) Placement agent commissions and other offering costs Proceeds From Issuance Of Common Stock And Prefunded Warrants From Private Placement Net Of Placement Agent Commissions And Other Offering Costs Proceeds from issuance of common stock and prefunded warrants from private placement net of placement agent commissions and other offering costs. 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Operating lease liability, long-term portion Operating Lease, Liability, Noncurrent Operating lease liability Quoted Prices in Active Markets for Identical Assets (Level 1) Fair Value, Inputs, Level 1 [Member] Class of Stock [Line Items] Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash used in by financing activities Net cash provided by (used in) financing activities Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Asset Acquisition [Abstract] Other (income) expense: Nonoperating Income (Expense) [Abstract] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of Antidilutive Securities Excluded from Computation of Diluted Net Loss per Share Entity Interactive Data Current Entity Interactive Data Current Chemistry, manufacturing, and controls Chemistry Manufacturing And Controls Expense Chemistry manufacturing and controls expense. 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Agency Bonds [Member] Agency bonds Net product (loss) revenue Total revenue Total revenue Total revenue Maturities Greater than 1 Year Long Term Investment [Member] Long term investment. Class of Stock [Domain] Possible future issuance under equity compensation plan (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Cash and cash equivalents and investments Cash, Cash Equivalents, and Short-Term Investments Cash, Cash Equivalents, and Short-Term Investments, Total Schedule of Accrued Expenses Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Entity Emerging Growth Company Entity Emerging Growth Company Vested or expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Indefinite-Lived Intangible Assets [Axis]