75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Consolidated Balance Sheets (Unaudited)
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75020 - Statement - Condensed Consolidated Balance Sheets (Unaudited) (Parenthetical)
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75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited)
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75040 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited)
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75050 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited) (Parenthetical)
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75060 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited)
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995455 - Disclosure - Organization and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995495 - Disclosure - Property and Equipment, Net
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995505 - Disclosure - Accrued Expenses and Other Current Liabilities
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995515 - Disclosure - Asset Acquisitions
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995525 - Disclosure - License Agreements
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995535 - Disclosure - Stockholders' Equity
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995545 - Disclosure - Stock-based Compensation
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995555 - Disclosure - Leases
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995565 - Disclosure - Commitments and Contingencies
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995575 - Disclosure - Income Taxes
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995585 - Disclosure - Net Loss Per Share
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995595 - Disclosure - Related Party Transactions
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995605 - Disclosure - Segment Information
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995615 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995625 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995635 - Disclosure - Fair Value Measurements (Tables)
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995655 - Disclosure - Property and Equipment, Net (Tables)
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995665 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995675 - Disclosure - Stockholders' Equity (Tables)
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995685 - Disclosure - Stock-based Compensation (Tables)
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995695 - Disclosure - Leases (Tables)
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995705 - Disclosure - Net Loss Per Share (Tables)
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995715 - Disclosure - Organization and Basis of Presentation - Additional Information (Details)
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995725 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995735 - Disclosure - Summary of Significant Accounting Policies - Reconciliation of Cash, Cash Equivalents and Restricted Cash (Details)
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995745 - Disclosure - Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details)
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995755 - Disclosure - Fair Value Measurements - Additional Information (Details)
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995775 - Disclosure - Marketable Securities - Summary of Fair Values and Gross Unrealized Losses for Available-for-sale Securities (Details)
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995795 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details)
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995805 - Disclosure - Property and Equipment, Net - Additional Information (Details)
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995815 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995825 - Disclosure - Asset Acquisitions - Additional Information (Details)
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995835 - Disclosure - License Agreements - Additional Information (Details)
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995845 - Disclosure - Stockholders' Equity - Additional Information (Details)
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995855 - Disclosure - Stockholders' Equity - Summary of Common Stock Reserved for Future Issuance (Details)
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995865 - Disclosure - Stock-based Compensation - Additional Information (Details)
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995875 - Disclosure - Stock-based Compensation - Summary of Stock Option Activity (Details)
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995885 - Disclosure - Stock-based Compensation - Assumptions used to Determine Fair Value of Stock Option Grants (Details)
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995895 - Disclosure - Stock-based Compensation - Assumptions used to Determine Fair Value of Stock Option Grants (Parenthetical) (Details)
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995905 - Disclosure - Stock-based Compensation - Schedule of Stock-based Compensation Expense (Details)
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995915 - Disclosure - Leases - Additional Information (Details)
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995925 - Disclosure - Leases - Schedule of Lease costs (Details)
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995935 - Disclosure - Leases - Schedule of Future Minimum Lease Payments under Operating Leases (Details)
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995945 - Disclosure - Leases - Schedule of Future Minimum Lease Payments under Operating Leases (Details) 2
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995955 - Disclosure - Leases - Schedule of Future Minimum Lease Payments under Operating Leases (Details) 3
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995965 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995975 - Disclosure - Income Taxes - Additional Information (Details)
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995985 - Disclosure - Net Loss Per Share - Summary of Computation of Basic and Diluted Net Loss Per Share (Details)
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995995 - Disclosure - Net Loss Per Share - Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Details)
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996005 - Disclosure - Segment Information - Additional Information (Details)
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Accrued compensation
Accrued Employee Benefits, Current
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Preferred Stock, Shares Issued, Total
Preferred stock, shares issued
Statement of Financial Position Location, Balance [Domain]
Balance Sheet Location
Aggregate Offering Price
Aggregate offering price
Aggregate offering price
Aggregate offering price
License agreements.
License Agreements [Line Items]
License Agreements [Line Items]
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Supplemental disclosure of noncash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of noncash investing and financing activity:
Plan Name [Axis]
Plan Name
Unrealized losses 12 months or greater, Fair value
Available of sale securities, unrealized loss position, greater than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Offering period
Share-based compensation arrangement by share-based payment award offering period.
Share-based Compensation Arrangement by Share-based Payment Award Offering Period
US Government Agency Securities
US Government Agencies Debt Securities [Member]
Operating Expenses [Abstract]
Operating expenses:
Leasehold improvements and furniture impairment
Impairment of Leasehold and Furniture
Impairment of leasehold and furniture.
Significant Other Observable Inputs (Level 2)
Fair Value, Inputs, Level 2 [Member]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
US Government agencies long term securities.
US Government Agencies Long Term Securities [Member]
US Government Agency Securities
Common Stock, Shares Authorized
Common stock, shares authorized
Product and Service [Axis]
Product and Service
Document Fiscal Period Focus
Document Fiscal Period Focus
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Entity Shell Company
Entity Shell Company
Short-Term Investments [Member]
Short-Term Investments
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalent
Cash and cash equivalents
Operating lease assets impairment
Operating Lease, Impairment Loss
Common stock, shares issued
Common Stock, Shares, Issued
Common Stock, Shares, Issued, Total
Ending balance, shares
Beginning balance, shares
Beginning balance, shares
Common stock, shares issued
Asset Class [Domain]
Asset Class
Statement [Table]
Statement [Table]
Laboratory equipment.
Laboratory Equipment [Member]
Laboratory Equipment
Restricted Cash, Noncurrent
Restricted cash
Letter of credit provided to lessor
Operating leases cancellable and non-cancellable expiration dates
Operating leases cancelable and non-cancellable expiration dates.
Operating Leases Cancelable and Non-Cancellable Expiration Dates
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value of options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Percentage of fair market value of common stock
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Entity Filer Category
Entity Filer Category
License Agreement Effective Termination Date
License agreement effective termination date.
License agreement effective termination date
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Payments to Acquire Marketable Securities, Total
Payments to Acquire Marketable Securities
Purchases of marketable securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted-average exercise price, Options exercisable at June 30, 2021
Weighted-average exercise price, Options exercisable at March 31, 2026
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Lessee operating lease liability payments due after Year four.
Lessee Operating Lease Liability Payments Due After Year Four
Operating Lease Payments, Thereafter
Operating Sublease Receipts Due Next Twelve Months
Operating sublease receipts due next twelve months.
Operating Sublease Receipts, 2027
Commercial paper short term.
Commercial Paper Short Term [Member]
Commercial Paper
Stock Options Issued and Outstanding
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Cash, Cash Equivalents and Restricted Cash
Debt Securities, Available-for-Sale, Term
Maturity
Additional paid-in capital
Additional Paid in Capital, Common Stock
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Share-based compensation, options granted that vest based on performance milestone
Stock options outstanding, granted
Shares Granted
Summary of Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
US Government Agency Securities
US Government Agencies Short Term Securities [Member]
US Government agencies short term securities.
Estimated Shares Purchasable Under The Employee Stock Purchase Plan Member
Estimated Shares Purchasable Under the ESPP
Estimated shares purchasable under the employee stock purchase plan.
Net loss per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Office Space [Member]
Office space.
Office Space
NonRule10b51ArrModifiedFlag
NonRule10b51ArrModifiedFlag
Non-Rule 10b5-1 Arrangement Modified
Stock options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Shares Outstanding at December 31, 2024
Shares Outstanding at March 31, 2026
Lessor, Operating lease existence of option to terminate [true false]
Lessor, Operating Lease, Existence of Option to Terminate [true false]
Interest Income (Expense), Nonoperating
Interest income
Liabilities, Current
Total current liabilities
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Accrued milestone payment as underlying contingencies
Accrued Milestone Payment as Underlying Contingencies
Accrued milestone payment as underlying contingencies.
Notice period for cancellation of lease.
Notice Period For Cancellation Of Lease
Notice period for cancellation of lease
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Entity Small Business
Entity Small Business
Amounts accrued for deferred offering costs.
Amounts Accrued For Deferred Offering Costs
Amounts accrued for deferred offering costs
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Shares Canceled
Weighted average price per share
Price per share
Sale of Stock, Price Per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Aggregate intrinsic value, Exercised
Intrinsic value of options exercised
In-process research and development expenses
In-process research and development
In Process Research And Development Expense
In process research and development expense.
Share-Based Payment Arrangement [Text Block]
Stock-based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
2018 equity incentive plan.
Two Thousand Eighteen Equity Incentive Plan [Member]
2018 Equity Incentive Plan
Lease Contractual Term [Axis]
David M. Chacko [Member]
David M. Chacko.
David M. Chacko [Member]
Leases [Abstract]
Lessee, Lease, Description [Line Items]
Lessee Lease Description [Line Items]
Amendment Flag
Amendment Flag
Product and Service
Product and Service [Domain]
Liabilities and Equity [Abstract]
Liabilities, Convertible Preferred Stock and Stockholders' Equity (Deficit)
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Joyo License Agreement
Joyo License Agreement [Member]
Joyo license agreement.
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Net proceeds from underwritten offering
Net Proceeds From Underwritten Offering
Net proceeds from underwritten offering.
Guangzhou Joyo Pharmatech Co., Ltd [Member]
Guangzhou Joyo Pharmatech Co., Ltd.
Gunagzhou Joyo Pharmatech Co., Ltd.
Common Stock [Member]
Common Stock
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted-average exercise price, Granted
Lessee, Operating Lease, Liability, to be Paid, Year Three
Operating Lease Payments, 2029
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less accumulated depreciation and amortization
Increase (decrease) in prepaid expenses and other current and long-term assets.
Increase Decrease In Prepaid Expenses And Other Current And Long Term Assets
Prepaid expenses and other current and long-term assets
Debt Securities, Available-for-Sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Term for cancellation of lease.
Term For Cancellation Of Lease
Term for cancellation of lease
Vesting of early exercised options.
Vesting Of Early Exercised Options
Vesting of early exercised options
Entity Address, Address Line One
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Assumptions used to Determine Fair Value of Stock Option Grants
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Earnings Per Share [Abstract]
Equity Securities without Readily Determinable Fair Value, Amount
Investment in equity securities
Statement of Financial Position Location, Balance [Axis]
Balance Sheet Location
Investment Type [Axis]
Investment Type
Operating Lease, Right-of-Use Asset
Operating lease assets
Fair value, Total
Available for sale securities, gross unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position
Total sublease receipts
Operating Sublease Receipts Due
Operating sublease receipts due.
Payment for option to expand territory of license after first dosing of first patient
Payment for Option to Expand Territory of License After First Dosing of First Patient
Payment for option to expand territory of license after first dosing of first patient.
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Unrealized (loss) gain on marketable securities, net
2024 ATM Offering.
Two Thousand Twenty Four ATM Offering [Member]
2024 ATM Offering
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Computer Equipment and Software
Computer Equipment And Software.
Computer Equipment And Software [ Member ]
Asset Acquisition [Table]
Investments, Debt and Equity Securities [Abstract]
Valuation Approach and Technique [Axis]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net (decrease) increase in cash, cash equivalents, and restricted cash
Subsequent Event Type [Domain]
Anti-dilutive securities excluded from calculation of diluted net loss per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Common Stock, Par or Stated Value Per Share
Common stock, par value
Security Deposit
Security deposit paid
Ebun Garner [Member]
Ebun Garner.
Ebun Garner [Member]
Weighted-average remaining contractual term (years), Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, maximum
Debt Securities, Available-for-Sale, Amortized Cost
Available for sale securities, Amortized cost
Debt Securities, Available-for-sale, Total
Debt Securities, Available-for-Sale
Available for sale securities, Estimated fair value
Reimbursement of certain initial manufacturing costs.
Reimbursement Of Certain Initial Manufacturing Costs
Reimbursement of certain initial manufacturing costs
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of stock options, shares
Shares Exercised
State and Local Income Tax Expense (Benefit), Continuing Operations, Total
State and Local Income Tax Expense (Benefit), Continuing Operations
Provision for state income taxes
Current Fiscal Year End Date
Current Fiscal Year End Date
NiKang Therapeutics, Inc.
Ni Kang Therapeutics Incorporation [Member]
NiKang Therapeutics, Inc.
Document Quarterly Report
Document Quarterly Report
Entity Address, State or Province
Entity Address, State or Province
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Preferred stock, shares outstanding
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Available for sale securities, Unrealized gains
Common stock reserved for future issuance
Common stock issuable upon conversion
Common Stock, Capital Shares Reserved for Future Issuance
Marketable Securities, Current, Total
Marketable Securities, Current
Short-term marketable securities
Schedule of Stock-based Compensation Expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Expenses and Other Current Liabilities
Second licensed product.
Second Licensed Product [Member]
Second Licensed Product
Subsequent Event [Member]
Subsequent Event
Marketable Securities, Policy [Policy Text Block]
Marketable Securities and Investments
Lease commencement month and year.
Lease Commencement Month And Year
Lease commencement month and year
Property, Plant and Equipment [Abstract]
Other Assets, Noncurrent, Total
Other Assets, Noncurrent
Other assets
Share-based compensation, options repriced
Share-Based Compensation Arrangement by Share-Based Payment Award, Options Repriced in Period
Share-based compensation arrangement by share-based payment award, options repriced in period.
Antidilutive Securities [Axis]
Antidilutive Securities
License agreements.
License Agreements [Abstract]
ATM Offering [Member]
ATM Offering.
ATM Offering
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Sales of marketable securities
Proceeds from Sale of Debt Securities, Available-for-Sale
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss)
Amendment To The September Two Thousand Twenty Four Sublease [Member]
Amendment to the september two thousand twenty four sublease.
Amendment to september 2024 Sublease
Office space leases
Building subject to ground leases.
Building Subject To Ground Leases
Operating lease option to extend
Lessee, Operating Lease, Option to Extend
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred stock, $0.0001 par value; 80,000,000 shares authorized at March 31, 2026 and December 31, 2025; no shares issued and outstanding at March 31, 2026 and December 31, 2025
Minimum [Member]
Minimum
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Underwriting discounts and commissions.
Underwriting Discounts And Commissions
Underwriting discounts and commissions
Fair Value, Inputs, Level 3 [Member]
Significant Unobservable Inputs (Level 3)
Segment Reporting [Abstract]
Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Current, Statement of Financial Position [Extensible Enumeration]
Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Current, Statement of Financial Position [Extensible Enumeration]
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets Measured at Fair Value on Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Options to purchase common stock.
Options To Purchase Common Stock [Member]
Options to Purchase Common Stock
Related Party Transactions [Abstract]
Schedule of Future Minimum Lease Payments and Sublease Receipts Under Operating Leases
Schedule Of Future Minimum Lease Payments And Sublease Receipts Under Operating Leases [Table Text Block]
Schedule of future minimum lease payments and sublease receipts under operating leases.
Underwriting discounts and commissions and offering costs, net
Underwriting Discounts and Commissions and Offering Costs, Net
Underwriting discounts and commissions and offering costs, net.
Summary of Fair Values and Gross Unrealized Losses for Available-for-sale Securities
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Sublease income
Sublease income
Sublease Income
Accounts Payable and Accrued Liabilities [Member]
Accrued Expenses and Other Current Liabilities
Restricted Cash and Cash Equivalents, Total
Restricted Cash and Cash Equivalent
Restricted cash
Accrued property and equipment current.
Accrued Property and Equipment Current
Accrued property and equipment
Commitments and Contingencies
Commitments and contingencies (Note 11)
September Two Thousand Twenty Four Sublease [Member]
September two thousand twenty four sublease.
September 2024 Sublease
General and Administrative Expense
General and Administrative Expense [Member]
General and Administrative
Operating lease liabilities
Operating Lease, Liability
Operating lease liabilities
License Agreement Termination Date
License agreement termination date
License agreement termination date
Marketable Securities, Noncurrent
Long-term marketable securities
Lessee, Lease, Description [Table]
Lessee Lease Description [Table]
Text Block [Abstract]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Lease Contractual Term [Domain]
Noncash impairment charge
Impairment charge on operating lease assets and property and equipment
Impairment Charge on Operating Lease Assets and Property and Equipment
Impairment charge on operating lease assets and property and equipment.
Weighted-average shares of common stock used in computing net loss per share, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Scenario [Axis]
Scenario
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value, Options exercisable at June 30, 2021
Aggregate intrinsic value, Options exercisable at March 31, 2026
Segment Reporting, Expense Information Used by CODM, Description
Share-based payment arrangement, incremental cost
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
License agreements.
License Agreements [Table]
License Agreements [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Unrealized losses 12 months or greater, Unrealized losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Laboratory Space [Member]
Laboratory space.
Laboratory Space
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Accrued Research and Development Expenses Current
Accrued research and development expenses current.
Accrued research and development expenses
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Preferred Stock, Par or Stated Value Per Share
Undesignated preferred stock par value
Preferred stock, par value
Operating lease option to extend
Lessee, Operating Lease, Existence of Option to Extend [true false]
Operating lease existence of option to extend [true false]
Statement of Stockholders' Equity [Abstract]
Valuation Approach and Technique [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Leasehold Improvements [Member]
Leasehold Improvements
Straight-line Basis Through Premium End Date
Straight-line Basis Through Premium End Date [Member]
Straight-line basis through premium end date.
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Disclosures [Text Block]
Fair Value Measurements
US treasury securities short term.
US Treasury Securities Short Term [Member]
US Treasury Securities
Accrued Liabilities and Other Liabilities
Accrued expenses and other current liabilities
Total
Common Stock Shares Issuable Value
Common stock shares issuable value.
Aggregate Offering Price
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Share based compensation by share based payment award common stock granted in period, term.
Share Based Compensation By Share Based Payment Award Common Stock Granted In Period Term
Share-based compensation, common stock grant in period, term
Plan Name [Domain]
Plan Name
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Credit Facility [Axis]
Credit Facility
Increase (decrease) in operating lease assets and liabilities, net.
Increase Decrease In Operating Lease Assets And Liabilities Net
Operating lease assets and liabilities, net
Available-for-sale securities, accrued interest
Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Current
Other Noncurrent Assets [Member]
Other Assets
Development and regulatory milestone payments obligation if territory expanded
Development and Regulatory Milestone Payments Obligation if Territory Expanded
Development and regulatory milestone payments obligation if territory expanded.
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Related and Nonrelated Parties [Axis]
Marketable Security, Realized Gain (Loss)
Realized gain from sales of marketable securities, net
Realized gain from sales of marketable securities, net
Asset Acquisitions
Asset Acquisition [Text Block]
Medshine Discovery Inc.
Medshine Discovery Inc. [Member]
Medshine Discovery Inc.
Unvested early exercised stock option liability.
Unvested Early Exercised Stock Option Liability
Unvested early exercised stock option liability
Entity Address, City or Town
Entity Address, City or Town
2021 Incentive Award Plan
Two thousand twenty one incentive award plan.
Two Thousand Twenty One Incentive Award Plan [Member]
Number of reporting segment
Number of Reportable Segments
Upfront payment.
Upfront Payment
Upfront payment
Security Exchange Name
Security Exchange Name
Credit Facility [Domain]
Credit Facility
January Two Thousand Twenty Four Sublease [Member]
January two thousand twenty four sublease.
January 2024 Sublease
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property and equipment
Prepaid Rent
Prepaid rent
Counterparty Name [Axis]
Counterparty Name
July Two Thousand Twenty Four Sublease [Member]
July two thousand twenty four sublease.
July 2024 Sublease
Commercial milestone payments obligation.
Commercial Milestone Payments Obligation
Commercial milestone payments obligation
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Tenant improvement allowance.
Tenant Improvement Allowance
Tenant improvement allowance
Less: Tenant improvement allowance receivable
Less: Tenant improvement allowance receivable
Decrease in stock option, exercise price
Stock Option, Exercise Price, Decrease
Underwritten Offering
Underwritten Offering [Member]
Underwritten Offering [Member]
Cash, cash equivalents and restricted cash at end of the period
Cash, cash equivalents and restricted cash at beginning of the period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Total cash, cash equivalents and restricted cash
Statistical Measurement
Statistical Measurement [Domain]
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock-based compensation
Common stock reserved for future issuance.
Common Stock Reserved For Future Issuance [Table Text Block]
Summary of Common Stock Reserved for Future Issuance
Document Period End Date
Document Period End Date
Development and regulatory milestone payments obligation.
Development And Regulatory Milestone Payments Obligation
Development and regulatory milestone payments obligation
Shares Available for Purchase Under Employee Stock Purchase Plan
Shares Available for Purchase Under Employee Stock Purchase Plan [Member]
Shares Available for Purchase Under ESPP
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Shares Options exercisable at June 30, 2021
Shares Options exercisable at March 31, 2026
Two thousand twenty four lease.
Two Thousand Twenty Four Lease [Member]
2024 Lease
License agreements.
License Agreements Disclosure Text Block
License Agreements
Statement of Financial Position [Abstract]
Operating Sublease Receipts Due Year Two
Operating sublease receipts due year two.
Operating Sublease Receipts, 2028
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Available of sale securities, unrealized loss position, Number of positions
Affini T Therapeutics, Inc.
Affini-T Therapeutics, Inc Member.
Affini-T Therapeutics, Inc Member
Affini T therapeutics inc
Liabilities
Total liabilities
Total liabilities
Operating lease discount rate
Lessee, Operating Lease, Discount Rate
Financial Instruments [Domain]
Foreign Income Tax Expense (Benefit), Continuing Operations, Total
Foreign Income Tax Expense (Benefit), Continuing Operations
Provision for foreign income taxes
US treasury securities long term.
US Treasury Securities Long Term [Member]
US Treasury Securities
At the time option is granted.
At Time Option Is Granted [Member]
At the Time Option is Granted
Lessee, Operating Lease, Liability, to be Paid, Year Two
Operating Lease Payments, 2028
Unrealized losses less than 12 months, Unrealized losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Available of sale securities, unrealized loss position, greater than 12 months, Number of positions
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions
Weighted-average shares of common stock used in computing net loss per share, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Percentage of commission on gross sales proceeds
Percentage Of Commission On Gross Sales Proceeds
Percentage of commission on gross sales proceeds
Medshine License Agreement
Medshine License Agreement [Member]
Medshine license agreement.
Securities Act File Number
Entity File Number
Amounts accrued for purchase of property and equipment.
Amounts Accrued For Purchase Of Property And Equipment
Amounts accrued for purchases of property and equipment
Unrealized gain (loss) on marketable securities, net
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Payment Related to License Option Exercise
Payment related to license option exercise.
Amounts accrued for offering costs
Amounts accrued for offering costs
Amounts accrued for offering costs
Amounts accrued for offering costs
Cover [Abstract]
Lessee Operating Sublease Receipts Fiscal Year Maturity [Abstract]
Lessee operating sublease receipts fiscal year maturity.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, minimum
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Percentage of outstanding common stock maximum
Investments [Domain]
Investments
Operating leases Noncancelable expiration dates.
Operating Leases Non Cancelable Expiration Dates
Operating leases Noncancelable expiration dates
Scenario [Domain]
Scenario
US Treasury Securities [Member]
US Treasury Securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Shares of common stock, authorized for issuance
Sale of Stock [Domain]
Sale of Stock
Share-based compensation arrangement by share-based payment award, shares subject to repurchase.
Share Based Compensation Arrangement By Share Based Payment Award Shares Subject To Repurchase
Share-based compensation, shares subject to repurchase
Segment Reporting Disclosure [Text Block]
Segment Information
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Yankee Debt Securities [Member]
Yankee debt securities.
Yankee Debt Securities
Operating Sublease Receipts Due Year Four
Operating sublease receipts due year four.
Operating Sublease Receipts, 2030
Payment related to publication of US patent application.
Payment Related To Publication Of U S Patent Application
Payment for US patent application
Phase 2 Clinical Trial
Phase 2 Clinical Trial [Member]
Phase 2 Clinical Trial.
Tax Cuts and Jobs Act Research and Development Expenses Capitalized and Amortized Period
Tax cuts and jobs act research and development expenses capitalized and amortized period.
Tax cuts and jobs act research and development expenses capitalized and amortized period
ESPP
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
Recently Issued Accounting Pronouncements Not Yet Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Stock vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, minimum
Percentage of reduction in workforce.
Percentage of Reduction in Workforce
Percentage of reduction in workforce
Corporate debt securities short term member
CorporateDebtSecuritiesShortTerm[Member]
Corporate Debt Securities
Milestones accrued.
Milestones Accrued
Milestones accrued
Operating lease initial term
Lessee, Operating Lease, Term of Contract
Lease initial term
Common Stock, Shares, Outstanding
Ending balance, shares
Beginning balance, shares
Common stock, shares outstanding
Operating Lease, Liability, Current
Operating lease liabilities
Depreciation and amortization
Depreciation, Depletion and Amortization, Total
Depreciation, Depletion and Amortization
Depreciation and amortization expense
Document Transition Report
Document Transition Report
Operating Expenses
Total operating expenses
Off-Balance-Sheet Credit Exposure, Policy [Policy Text Block]
Concentration of Credit Risk and Off-Balance Sheet Risk
For holders of more than 10% of the Company’s combined voting power of all classes of stock.
For Holders Of More Than Ten Percent Of Combined Voting Power Of All Classes Of Stock [Member]
For Holders of More Than 10% of Company's Total Combined Voting Power of All Classes of Stock
Lessee, Operating Leases [Text Block]
Leases
Statement of Cash Flows [Abstract]
Issuance of common stock
Contribution of common stock
Stock issued, value
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
Assets, Fair Value Disclosure [Abstract]
Assets:
Stockholders' Equity
Equity [Text Block]
Earnings Per Share [Text Block]
Net Loss Per Share
Jefferies LLC
Jefferies LLC [Member]
Jefferies LLC Member
Net loss
Net loss
Aggregate intrinsic value, Outstanding
Aggregate intrinsic value, Outstanding at June 30, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value, Outstanding at December 31, 2021
Operating lease cost
Operating Lease, Cost
Share-based compensation, liabilities associated with shares issued with repurchase rights
Deferred Compensation Share-Based Arrangements, Liability, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Operating Lease, Payments
Cash paid for operating leases
Assets [Abstract]
Assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Awards available for future grant.
Awards Available For Future Grant [Member]
Awards Available for Future Grant
Document Fiscal Year Focus
Document Fiscal Year Focus
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Unaudited interim financial information.
Unaudited Interim Financial Information [Policy Text Block]
Unaudited Interim Financial Information
Research and Development Expense
Research and Development Expense [Member]
Research and Development
Marketable Securities
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Long-term investments.
Long-Term Investments
Long-Term Investments [Member]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Straight-line Basis Over Greater of Period Through Premium End Date
Straight-line Basis Over Greater of Period Through Premium End Date [Member]
Straight-line basis over greater of period through premium end date.
First licensed product.
First Licensed Product [Member]
First Licensed Product
Proceeds from the exercise of stock options
Proceeds from Stock Options Exercised
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Purchase period
Share-based compensation arrangement by share-based payment award purchase period.
Share-based Compensation Arrangement by Share-based Payment Award Purchase Period
Lessee, Operating Lease, Liability, to be Paid, Year One
Operating Lease Payments, 2027
Share-Based Payment Arrangement [Abstract]
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Total fair value of assets
Operating Sublease Receipts Due Year Three
Operating sublease receipts due year three.
Operating Sublease Receipts, 2029
Sale of Stock [Axis]
Sale of Stock
Proceeds from private placement, after deducting placement agent fees and expenses
Proceeds From Issuance Of Private Placement After Deducting Placement Agent Fees And Expenses
Proceeds from issuance of private placement after deducting placement agent fees and expenses.
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash (used in) provided by investing activities
Private Placement
Private Placement [Member]
Title of 12(b) Security
Title of 12(b) Security
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted-average exercise price, Canceled
One Big Beautiful Bill Act Research and Development Expenses Capitalized and Amortized Period
One big beautiful bill act research and development expenses capitalized and amortized period.
OBBBA research and development expenses capitalized and amortized period
Money Market Funds [Member]
Money Market Funds
Related and Nonrelated Parties [Domain]
Option Repricing
Option Repricing [Member]
Option repricing.
Income Tax Disclosure [Text Block]
Income Taxes
Payment of Development and Regulatory Milestone Obligation
Payment of Development and Regulatory Milestone Obligation
Payment of development and regulatory milestone obligation
Sublease Extended Term
Sublease extended term.
Sublease extended term
Other accruals and current liabilities
Other accruals and current liabilities.
Other Accruals And Current Liabilities
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Operating Lease Payments, 2026 (remaining nine months)
Other liabilities
Other Liabilities, Noncurrent
Operating Sublease Receipts Due Remainder Of Fiscal Year
Operating sublease receipts due remainder of fiscal year
Operating Sublease Receipts, 2026 (remaining nine months)
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted-average exercise price, Outstanding at December 31, 2024
Weighted-average exercise price, Outstanding at March 31, 2026
LifeArc.
Life Arc [Member]
LifeArc
License agreement.
License Agreement [Member]
License Agreement
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Measurement Frequency [Domain]
Measurement Frequency
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, maximum
Options early exercised subject to future vesting.
Options Early Exercised Subject To Future Vesting [Member]
Options Early Exercised Subject to Future Vesting
Subsequent Event Type [Axis]
Impairment charge on investment in equity securities
Impairment adjustment to equity investment
Impairment Charge on Investment in Equity Securities
Impairment charge on investment in equity securities.
Facility Lease Termination Description
Facility lease termination description.
Facility lease termination description
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Fair Value, Recurring [Member]
Fair Value, Recurring
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Operating lease, aggregate monthly payments to lessor
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: Amount representing interest
Equity Components [Axis]
Equity Components
Research and Development Expense (Excluding Acquired in Process Cost)
Research and development
Total other income (expense), net
Nonoperating Income (Expense)
Equity Component [Domain]
Equity Component
Asset Class [Axis]
Asset Class
Operating Sublease Receipts Due After Year Four
Operating sublease receipts due after year four.
Operating Sublease Receipts , Thereafter
Business Combination [Axis]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Shares issued under ESPP
Issuance of common stock under the Employee Stock Purchase Plan, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Share-based compensation, plan expiration period
Common stock, voting rights
Common Stock, Voting Rights
Maximum [Member]
Maximum
Rule10b51ArrModifiedFlag
Rule10b51ArrModifiedFlag
Rule 10b5-1 Arrangement Modified
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted-average exercise price, Exercised
Payment for option to expand territory of license on or prior to first dosing of first patient
Payment for Option to Expand Territory of License on or Prior to First Dosing of First Patient
Payment for option to expand territory of license on or prior to first dosing of first patient.
Novartis Pharma AG
Novartis Pharma AG [Member]
Novartis Pharma AG [Member]
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Common stock, $0.0001 par value; 800,000,000 shares authorized at March 31, 2026 and December 31, 2025; 310,806,888 and 284,159,076 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively
Line of Credit Facility, Expiration Date
Line of credit facility, expiration date
Asana merger agreement.
Asana Merger Agreement [Member]
Asana Merger Agreement
Underwriters option to purchase additional shares
Underwriters Option To Purchase Additional Shares
Underwriters option to purchase additional shares.
First Amendment to 2020 Lease
First Amendment to Two Thousand and Twenty Lease [Member]
First Amendment to 2020 lease.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Preferred Stock, Shares Authorized
Undesignated preferred stock authorized
Preferred stock, shares authorized
Lessor, Operating lease initial term
Lessor, Operating Lease, Term of Contract
Shannon Morris [Member]
Shannon Morris.
Shannon Morris [Member]
Unrealized losses, Total
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Entity Registrant Name
Entity Registrant Name
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Available for sale securities, Unrealized losses
Measurement at fair value, transfers among Level 1, Level 2 or Level 3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Payments to Acquire in Process Research and Development
In-process research and development
Adjustments to value of investment in equity securities
Equity securities without readily determinable fair value, impairment or price adjustment amount.
Equity Securities Without Readily Determinable Fair Value, Impairment or Price Adjustment Amount
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income (expense), net
Lessor, Operating lease existence of option to extend [true false]
Lessor, Operating Lease, Existence of Option to Extend [true false]
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Measurement Frequency [Axis]
Measurement Frequency
Net proceeds from offering
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock in underwritten offering
Other Comprehensive Income (Loss), Tax [Abstract]
Other comprehensive income (loss):
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive (loss) income
Federal Income Tax Expense (Benefit), Continuing Operations, Total
Federal Income Tax Expense (Benefit), Continuing Operations
Provision for federal income taxes
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Restrictions on Cash and Cash Equivalents [Table Text Block]
Reconciliation of Cash, Cash Equivalents and Restricted Cash
Assets
Total assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted-average remaining contractual term (years), Options exercisable at March 31, 2026
Income Statement [Abstract]
Sale of Stock, Number of Shares Issued in Transaction
Number of stock sold
Black-Scholes Option Pricing Model
Black-Scholes Option Pricing Model [Member]
Black-Scholes option pricing model.
Issuance of common stock, share
Stock issued and sold
Stock issued
Share-based payment arrangement, withheld on behalf of employees for future purchase.
Share-based Payment Arrangement, Withheld on Behalf of Employees for Future Purchase
Share-based payment arrangement, withheld on behalf of employees for future purchase
Net loss per share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
City Area Code
City Area Code
Income Tax Examination, Penalties and Interest Expense, Total
Income Tax Examination, Penalties and Interest Expense
Interest or penalties related to income taxes
Katmai Pharmaceuticals, Inc.
Katmai Pharmaceuticals Incorporation [Member]
Katmai Pharmaceuticals, Inc.
Counterparty Name [Domain]
Counterparty Name
Variable Lease, Cost
Variable lease costs
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, weighted-average remaining lease term
Total lease cost
Lease, Cost
Total lease cost
Letter of Credit [Member]
Letter of Credit
Operating lease cancellation payment.
Operating Lease Cancellation Payment
Operating lease cancellation payment
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Cash, cash equivalents and restricted cash at end of the period
Cash, cash equivalents and restricted cash at beginning of the period
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Operating Income (Loss)
Loss from operations
Retained Earnings [Member]
Accumulated Deficit
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Offering costs
Payments of Stock Issuance Costs
Placement agent fees and estimated expenses
Issuance costs associated with underwritten offering
New investment obligation in equity securities
Obligation accrued for investment in equity securities
Obligation Accrued for Investment in Equity Securities
Obligation accrued for investment in equity securities.
Sovereign Debt Securities
Unrealized losses less than 12 months, Fair value
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, weighted-average discount rate
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Operating lease liabilities, net of current portion
Fair Value, Inputs, Level 1 [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1)
Class of Stock [Line Items]
At The Market offering.
At The Market Offering [Member]
ATM offering
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Lease, Cost [Table Text Block]
Schedule of Lease costs
Asset Acquisition [Abstract]
Nonoperating Income (Expense) [Abstract]
Other income (expense)
Marketable Securities [Table Text Block]
Summary of Marketable Securities Accounted for Available-for-Sale Securities
US Government Agency Securities
US Government Corporations and Agencies Securities [Member]
Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Accrued expenses and other current and long-term liabilities
Increase Decrease In Accrued Expenses And Other Current And Long-term Liabilities
Increase decrease in accrued expenses and other current and long-term liabilities.
Corporate Debt Securities [Member]
Corporate Debt Securities
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Charges in connection with reduction in force
Charges in Connection with Reduction in Force
Charges in connection with reduction in force.
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Furniture and Fixtures [Member]
Furniture and Fixtures
Asset Acquisition [Line Items]
Convertible Preferred Stock, Shares Issued upon Conversion
Conversion of convertible preferred stock into common stock
Accretion on marketable securities, net
Accretion (Amortization) of Discounts and Premiums, Investments
Lease discount rate
Discount Rate Used In Fair Value Of Operating Lease Assets And Property And Equipment
Discount rate used in fair value of operating lease assets and property and equipment.
Amounts accrued for in-process research and development expenses
Amounts accrued for in-process research and development expenses
Amounts accrued for in-process research and development
Common Stock, Dividends, Per Share, Declared
Common stock, dividends declared
Entity Tax Identification Number
Entity Tax Identification Number
Maturities of marketable securities
Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-Sale
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Organization and Basis of Presentation
Two thousand twenty one lease.
Two Thousand Twenty One Lease [Member]
2021 Lease
Local Phone Number
Local Phone Number
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to unvested stock option grants
Issuance of common stock, costs
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Two thousand twenty lease.
Two Thousand Twenty Lease [Member]
2020 Lease
Accounting Policies [Abstract]
Sales milestone payments obligation.
Sales Milestone Payments Obligation
Sales milestone payments obligation
Lessee, Operating Lease, Liability, to be Paid, Year Four
Operating Lease Payments, 2030
Cash and Cash Equivalents
Cash and Cash Equivalents [Member]
Commercial Paper [Member]
Commercial Paper
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized compensation cost expected to be recognized as expense, period
Accrued Professional Fees, Current
Accrued professional services
Cash, Cash Equivalents, and Short-term Investments, Total
Cash, Cash Equivalents, and Short-Term Investments
Cash, cash equivalents, and short-term marketable securities
Cash, cash equivalents and marketable securities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Stock, Class of Stock [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company