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  <xsd:element name="MilestonePaymentsPaidForLicenseFee" id="chrs_MilestonePaymentsPaidForLicenseFee" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ScenarioNetSalesExceeding300MillionQuartersEndingSeptember302026Member" id="chrs_ScenarioNetSalesExceeding300MillionQuartersEndingSeptember302026Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ScenarioNetSalesExceeding350MillionQuartersEndingMarch312027Member" id="chrs_ScenarioNetSalesExceeding350MillionQuartersEndingMarch312027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ThresholdNetSalesPaymentTrigger" id="chrs_ThresholdNetSalesPaymentTrigger" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentsToBuyOutRightToReceiveFuturePayments" id="chrs_PaymentsToBuyOutRightToReceiveFuturePayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PropertyPlantAndEquipmentIncludingDiscontinuedOperationsNet" id="chrs_PropertyPlantAndEquipmentIncludingDiscontinuedOperationsNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WeightedAverageNumberOfSharesOutstandingBasicContinuingOperations" id="chrs_WeightedAverageNumberOfSharesOutstandingBasicContinuingOperations" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WeightedAverageNumberOfSharesOutstandingDilutedContinuingOperations" id="chrs_WeightedAverageNumberOfSharesOutstandingDilutedContinuingOperations" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WeightedAverageNumberOfSharesOutstandingBasicDiscontinuedOperations" id="chrs_WeightedAverageNumberOfSharesOutstandingBasicDiscontinuedOperations" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WeightedAverageNumberOfSharesOutstandingDilutedDiscontinuedOperations" id="chrs_WeightedAverageNumberOfSharesOutstandingDilutedDiscontinuedOperations" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationCostsAndExpensesAbstract" id="chrs_DisposalGroupIncludingDiscontinuedOperationCostsAndExpensesAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationSellingGeneralAndAdministrativeExpense" id="chrs_DisposalGroupIncludingDiscontinuedOperationSellingGeneralAndAdministrativeExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationTotalCostsAndExpenses" id="chrs_DisposalGroupIncludingDiscontinuedOperationTotalCostsAndExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet" id="chrs_DisposalGroupIncludingDiscontinuedOperationOtherIncomeExpenseNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="TransitionServicesAgreementPayablesAndAccruedLiabilitiesCurrent" id="chrs_TransitionServicesAgreementPayablesAndAccruedLiabilitiesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationTransactionExpense" id="chrs_DisposalGroupIncludingDiscontinuedOperationTransactionExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="RevenueParticipationLiabilityRoyaltyRevenuePayment" id="chrs_RevenueParticipationLiabilityRoyaltyRevenuePayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AccountsReceivablesNetOfChargeOff" id="chrs_AccountsReceivablesNetOfChargeOff" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="LegacyCustomerAgreementInventoryReplacementCommitmentMember" id="chrs_LegacyCustomerAgreementInventoryReplacementCommitmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MaximumPotentialCommitmentExposure" id="chrs_MaximumPotentialCommitmentExposure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SalesAgreementMember" id="chrs_SalesAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NetGain" id="chrs_NetGain" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="InventoryWorkInProcessCurrentAndNoncurrent" id="chrs_InventoryWorkInProcessCurrentAndNoncurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="InventoryFinishedGoodsCurrentAndNoncurrent" id="chrs_InventoryFinishedGoodsCurrentAndNoncurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="InterestExpenseContinuingOperation" id="chrs_InterestExpenseContinuingOperation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
</xsd:schema>
