v3.26.1
Long-Term Debt (Additional Information) (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Sep. 30, 2025
Dec. 31, 2025
Jun. 27, 2025
Debt Instrument [Line Items]          
Debt Instrument, Covenant Description The Loan Agreement contains customary representations and warranties, events of default and affirmative and negative covenants, including a minimum cash covenant (the “Minimum Cash Covenant”) requiring the Company to maintain specified levels of cash in accounts subject to a control agreement in favor of the Agent (“Qualified Cash”) during the period commencing on January 1, 2027. The Minimum Cash Covenant will initially be set at 60% of the then outstanding principal balance of the Term Loans, is subject to adjustment and will not be tested at any time when the Company’s market capitalization is greater than $1.65 billion. The Company is also required to maintain minimum net product revenue from the sale of z-rostudirsen and z-basivarsen starting nine months after U.S. Food and Drug Administration approval of z-rostudirsen or z-basivarsen (the “Minimum Revenue Covenant”) if the outstanding principal balance of the Term Loans exceeds $100.0 million. The Minimum Revenue Covenant will not be tested for any month to the extent that for each day during such month either (i) Qualified Cash is at least 100% of the Company’s outstanding obligations under the Loan Agreement or (ii) the Company’s market capitalization is greater than $1.65 billion and Qualified Cash is at least 50% of the Company’s outstanding obligations under the Loan Agreement. Certain negative covenants under the Loan Agreement limit the ability of the Company, among other things, to incur future debt, grant liens, make investments, make acquisitions, distribute dividends and sell assets, subject in each case to certain exceptions.        
Minimum cash covenant percentage 60.00%        
Excess Outstanding Principal Balance of Term Loan $ 100,000        
Term Loan Forclosure Interest Rate 5.50%        
Debt Issuance Costs $ 30 $ 0      
Term End Charges Rate of Loan 5.50%        
Next 12 Months $ 0        
Loan Forclosure Interest Rate On First Anniversary [Member]          
Debt Instrument [Line Items]          
Term Loan Forclosure Interest Rate 2.00%        
Loan Forclosure Interest Rate On First Anniversary to Prior Second Anniversary [Member]          
Debt Instrument [Line Items]          
Term Loan Forclosure Interest Rate 1.50%        
Loan Forclosure Interest Rate On Second Anniversary to Before Maturity Date [Member]          
Debt Instrument [Line Items]          
Term Loan Forclosure Interest Rate 0.75%        
Prime Rate [Member] | Floor Interest Rate [Member]          
Debt Instrument [Line Items]          
Term Loans Bears Interest at Floating Interest Rate 7.50%        
Term Loans Bears Interest at Floating Interest Rate Additional 2.45%        
Maximum [Member]          
Debt Instrument [Line Items]          
Market Capitalisation $ 1,650,000        
Outstanding Principal Balance Of Term Loan Percent 100.00%        
Minimum [Member]          
Debt Instrument [Line Items]          
Outstanding Principal Balance Of Term Loan Percent 50.00%        
Hercules Loan Agreement [Member]          
Debt Instrument [Line Items]          
Aggregate Principal Amount         $ 275,000
Debt Issuance Costs $ 1,600        
Debt Instrument, Interest Rate, Effective Percentage 11.30%        
Hercules Loan Agreement [Member] | Restricted Cash and Other Assets [Member]          
Debt Instrument [Line Items]          
Debt Issuance Costs     $ 500    
Vendor Financing Arrangement [ Member]          
Debt Instrument [Line Items]          
Total outstanding $ 6,200        
Max facility $ 14,000        
Interest rate 5.00%        
Initial Tranche Loan [Member] | Hercules Loan Agreement [Member]          
Debt Instrument [Line Items]          
Aggregate Principal Amount         100,000
Three Additional Tranche Loan [Member] | Hercules Loan Agreement [Member]          
Debt Instrument [Line Items]          
Aggregate Principal Amount         75,000
Three Additional Tranche Loan [Member] | Second Term Loan Tranche [Member]          
Debt Instrument [Line Items]          
Aggregate Principal Amount       $ 50,000  
Final Tranche Loan [Member] | Hercules Loan Agreement [Member]          
Debt Instrument [Line Items]          
Aggregate Principal Amount         $ 50,000