75000 - Document - Document and Entity Information
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75010 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS
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75020 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical)
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75030 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
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75040 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Parenthetical)
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75050 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT)
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75060 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) (Parenthetical)
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75070 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
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995455 - Disclosure - Nature of the business and basis of presentation
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995465 - Disclosure - Summary of significant accounting policies
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995475 - Disclosure - Fair value measurements
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995495 - Disclosure - Property and equipment, net
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995505 - Disclosure - Accrued expenses and other current liabilities
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995515 - Disclosure - Stockholders' deficit
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995525 - Disclosure - Equity-based compensation
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995535 - Disclosure - Income taxes
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995545 - Disclosure - License agreements
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995555 - Disclosure - Collaboration revenue
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995565 - Disclosure - Commitments and contingencies
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995575 - Disclosure - Related party transactions
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995585 - Disclosure - Employee Benefit Plans
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995595 - Disclosure - Leases
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995605 - Disclosure - Net loss per share
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995615 - Disclosure - Segment information
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995625 - Disclosure - Summary of significant accounting policies (Policies)
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995635 - Disclosure - Fair value measurements (Tables)
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995655 - Disclosure - Property and equipment, net (Tables)
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995665 - Disclosure - Accrued expenses and other current liabilities (Tables)
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995675 - Disclosure - Stockholders' deficit (Tables)
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995685 - Disclosure - Equity-based compensation (Tables)
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995695 - Disclosure - Leases (Tables)
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995705 - Disclosure - Net loss per share (Tables)
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995715 - Disclosure - Segment information (Tables)
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995725 - Disclosure - Nature of the business and basis of presentation (Additional Information) (Details)
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995735 - Disclosure - Fair value measurements - Schedule of Fair Value Assets and Liabilities Measured on Recurring Basis (Details)
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995745 - Disclosure - Fair value measurements (Additional Information) (Details)
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995755 - Disclosure - Fair value measurements - Schedule of Aggregate Fair Values of the Preferred Stock Warrant Liability (Details)
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995785 - Disclosure - Property and equipment, net - Summary of Property and Equipment (Details)
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995795 - Disclosure - Property and equipment, net (Additional Information) (Details)
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995805 - Disclosure - Accrued expenses and other current liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995815 - Disclosure - Stockholders' deficit (Additional Information) (Details)
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995825 - Disclosure - Stockholders' deficit - Schedule of Common Stock Available for Future Issuance (Details)
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995835 - Disclosure - Equity-based compensation (Additional Information) (Details)
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995845 - Disclosure - Equity-based compensation - Summary of Stock Option Activity (Details)
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995855 - Disclosure - Equity-based compensation - Summary of Weighted-average Basis, Assumptions used in the Black Scholes option-pricing Model (Details)
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995865 - Disclosure - Equity-based compensation - Schedule of Stock-Based Compensation Expense (Details)
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995875 - Disclosure - Income taxes - Additional Information (Details)
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995885 - Disclosure - License agreements - Additional Information (Details)
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995895 - Disclosure - Collaboration revenue (Additional Information) (Details)
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995905 - Disclosure - Commitments and contingencies (Additional Information) (Details)
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995915 - Disclosure - Related party transactions (Additional Information) (Details)
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995925 - Disclosure - Employee Benefit Plans (Additional Information) (Details)
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995935 - Disclosure - Leases (Additional Information) (Details)
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995945 - Disclosure - Leases - Schedule of Weighted-average Remaining Lease Term and Discount Rates (Details)
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995955 - Disclosure - Leases - Schedule Components of Lease Costs (Details)
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995965 - Disclosure - Leases - Schedule of Maturity Analysis of Operating Lease Liabilities (Details)
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995975 - Disclosure - Leases - Schedule of Maturity Analysis of Operating Lease Liabilities (Details) 2
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995985 - Disclosure - Leases - Schedule of Other Information Related to Leases (Details)
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995995 - Disclosure - Net loss per share - Schedule of Basic And Diluted Net Loss Per Share Attributable To Common Stockholders (Details)
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996005 - Disclosure - Net loss per share - Schedule of Dilutive Securities Excluded From the Computation Of Diluted Net Loss Per Share Attributable To Common Stockholders (Details)
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996015 - Disclosure - Segment information (Additional Information) (Details)
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996025 - Disclosure - Segment information - Schedule of Significant Segment Expenses (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Weighted average exercise price, Cancelled
Amount owed to related party
Related Party Tax Expense, Due to Affiliates, Current
Segments [Domain]
Accrued compensation and benefit costs
Accrued Employee Benefits, Current
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Preferred stock issued
Contribution by the company under 401(k) plan
Defined Benefit Plan, Plan Assets, Contributions by Employer
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Balance as of March 31, 2025
Balance as of January 1, 2024
Accounts payable
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities:
Plan Name [Axis]
Research and Development Expense [Abstract]
Unallocated research and development expenses:
Equity [Abstract]
Entity Current Reporting Status
Operating Expenses [Abstract]
Operating expenses:
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
Commitments and contingencies
Commitments and Contingencies Disclosure [Text Block]
Common Stock, Shares Authorized
Common stock authorized
Temporary Equity, Par or Stated Value Per Share
Redeemable convertible preferred stock , par value
Agency Securities [Member]
Agency Bonds [Member]
Risks and uncertainties
Risks and uncertainties
Risks and uncertainties
Document Fiscal Period Focus
Document Fiscal Period Focus
External Research and Development Expenses [Abstract]
External research and development expenses.
Direct external research and development expenses:
Entity Shell Company
Redeemable convertible preferred stock , shares outstanding
Temporary Equity, Shares Outstanding
Redeemable convertible preferred stock, ending balance, Shares
Redeemable convertible preferred stock, beginning balance, Shares
Other Accrued Liabilities, Current
Other accrued expenses
Cash and cash equivalents
Cash and Cash Equivalent
Cash and Cash Equivalent, Total
Schedule Of Weighted Average Remaining Lease Term and Discount Rates Table Text Block
Schedule Of Weighted Average Remaining Lease Term and Discount Rates Table Text Block
Schedule of Weighted-average Remaining Lease Term and Discount Rates
Common Stock, Shares, Issued
Common Stock, Shares issued
Asset Class [Domain]
Statement [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value options granted
Statement [Line Items]
Warrant [Member]
Warrant [Member]
Entity Filer Category
Entity Filer Category
Net increase in cash, cash equivalents and restricted cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect, Continuing Operation
Net increase in cash, cash equivalents and restricted cash equivalents
Liabilities and Equity
Total liabilities, redeemable convertible preferred stock and stockholders' equity (deficit)
Payables and Accruals [Abstract]
Payments to Acquire Marketable Securities
Purchases of marketable securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted average exercise price, exercisable
Long-Lived Tangible Asset [Axis]
Options to purchase common stock [Member]
Investment Income, Interest
Interest income
Additional Paid in Capital, Common Stock
Additional paid-in capital
2026 Plan [Member]
Two Thousand Twenty Six Stock Option and Incentive Plan [Member]
Two thousand twenty six stock option and incentive plan.
Significant Accounting Policies [Text Block]
Summary of significant accounting policies
Property, Plant and Equipment [Line Items]
Partner Redeemable Convertible Preferred Stock [Member]
Partner Redeemable Convertible Preferred Stock [Member]
Partner redeemable convertible preferred stock
Collaboration Agreement [Member]
Collaboration Agreement [Member]
Other Comprehensive Income (Loss), before Tax, Portion Attributable to Noncontrolling Interest [Abstract]
Other comprehensive income:
Other comprehensive loss:
Two Thousand Twenty Six Employee Stock Purchase Plan [Member]
Two thousand twenty six employee stock purchase plan.
2026 ESPP [Member]
2026 Employee Stock Purchase Plan [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of stock options, granted
Net loss per share of common stock, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of stock options outstanding, beginning balance
Number of stock options outstanding, ending balance
Liabilities, Current
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash flows used in operating activities:
Lessee, Operating Lease, Liability, to be Paid, Year Five
2030
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Changes in the Carrying Value of the Contingent Consideration
Increase (Decrease) in Interest and Dividends Receivable
Increase (Decrease) in Interest and Dividends Receivable, Total
Interest receivable
Offering Costs Transferred to Additional Paid in Capital
Offering costs transferred to additional paid in capital.
Offering costs transferred to additional paid in capital
Deferred offering costs transferred to additional paid in capital
Initial Public Offering
Stockholders' Equity, Policy [Policy Text Block]
Stockholders' deficit:
Equity, Attributable to Parent [Abstract]
Entity Small Business
Entity Small Business
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Accumulated deficit
Other Commitments [Line Items]
Nature of the business and basis of presentation
Nature of Operations [Text Block]
Preferred Stock [Member]
Preferred Stock [Member]
Proceeds from initial public offering, net of underwriter discounts and commissions paid during the period
Proceeds from Issuance Initial Public Offering
Proceeds from initial public offering, net of underwriter discounts and commissions paid during the period
Sale of Stock, Price Per Share
Price per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Aggregate intrinsic value, Exercised
Share-Based Payment Arrangement [Text Block]
Equity-based compensation
2020 Equity Incentive Plan [Member]
Two Thousand Twenty Equity Incentive Plan [Member]
Two Thousand Twenty Equity Incentive Plan
Temporary Equity Conversion of Redeemable Convertible Preferred Stock to Common Stock Upon Closing of Initial Public Offering Shares
Temporary equity conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering shares.
Conversion of preferred stock to common stock upon closing of initial public offering, Shares
Lease Contractual Term [Axis]
Leases [Abstract]
Common Class A [Member]
Class A Common stock
Class A Common Stock [Member]
Project [Domain]
Lessee, Lease, Description [Line Items]
Amendment Flag
Amendment Flag
Liabilities and Equity [Abstract]
Liabilities, Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit)
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Operating lease liabilities
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Options to purchase common stock
Common Stock
Series B Redeemable Convertible Preferred Stock [Member]
Series B Redeemable Convertible Preferred Stock [Member]
Series B redeemable convertible preferred stock
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted average exercise price, Granted
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: Accumulated depreciation and amortization
Entity Address, Address Line One
Summary of Weighted-average Basis, Assumptions used in the Black Scholes option-pricing Model
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Marketable Securities [Table]
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
Numerator:
Temporary Equity, Carrying Amount, Attributable to Parent
Redeemable convertible preferred stock
Redeemable convertible preferred stock, beginning balance
Redeemable convertible preferred stock, ending balance
Numerator [Abstract]
Numerator [Abstract]
Numerator:
Stockholders' Equity Note, Redeemable Preferred Stock, Issue, Policy [Policy Text Block]
Reverse Stock Split
Investment Type [Axis]
Operating Lease, Right-of-Use Asset
Operating lease right-of use assets
Increase (Decrease) in Operatig Lease Right-Of-Use Assets
Increase (Decrease) in Operatig Lease Right-Of-Use Assets
Operating lease right-of-use assets
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Investments, Debt and Equity Securities [Abstract]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
anti-dilutive effect
Total
Common stock, par value
Common Stock, Par or Stated Value Per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted average remaining contractual life
Amortized Costs Basis
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost Basis
Fair Value
Debt Securities, Available-for-Sale
Debt Securities, Available-for-Sale, Total
Two Two Five Ac Ac AKY One One Eight Nine [Member]
Two Two Five Ac Ac AKY One One Eight Nine.
[225Ac]Ac-AKY-1189
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Number of stock options, exercised
Number of stock options, exercised
Exercise of common stock options, Shares
Marketable Securities
Marketable Securities
Total marketable securities
Accrued expenses and other current liabilities
Accrued Liabilities, Current
Total accrued expenses and other current liabilities
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Document Quarterly Report
Document Quarterly Report
Agency Bonds [Member]
Agency Bonds Member
Entity Address, State or Province
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of preferred stock to common stock upon closing of initial public offering
Preferred stock outstanding
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Unrealized Gain
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Common Stock, Capital Shares Reserved for Future Issuance
Total common stock authorized and reserved for future issuance
Common stock reserved for future issuance
Series A Redeemable Convertible Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock [Member]
Series A redeemable convertible preferred stock
Contract with Customer, Liability, Revenue Recognized
Contract inception collaboration revenue
Unreserved Common Stock Available for Future Issuance
Unreserved Common Stock Available for Future Issuance
Unreserved common stock available for future issuance
Information technology, facilities, office and other
Other General and Administrative Expense
Stock Issued During Period, Value, Stock Options Exercised
Exercise of common stock options
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued expenses and other current liabilities
Proceeds from Sale and Maturity of Marketable Securities
Proceeds from maturities of marketable securities
Schedule of Other Information Related to Leases
Schedule of Other Information Related to Leases [TableText Block]
Schedule of Other Information Related to Leases [TableText Block]
Number of securities
Number of securities
Accrued Research and Development Costs Current
Accrued research and development costs current.
Accrued research and development costs
Deferred Revenue, Current
Deferred Revenue, Current, Total
Deferred revenue, current portion
Property, Plant and Equipment [Abstract]
Conversion of Redeemable Convertible Preferred Stock into Common Stock Upon Closing of Initial Public Offering
Conversion of redeemable convertible preferred stock into common stock upon closing of initial public offering.
Conversion of redeemable convertible preferred stock into common stock upon closing of initial public offering
Antidilutive Securities [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Number of stock options, Cancelled
Aggregate intrinsic value, unvested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Other Commitments [Domain]
Available-for-Sale Securities [Member]
Related Party Transaction [Axis]
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income [Member]
Other Commitments [Table]
Preferred Stock, Value, Issued
Preferred stock carrying value
Proceed from issue of share
Revenue Recognition, Milestone Method, Revenue Recognized
Milestones Revenue
Minimum [Member]
Minimum [Member]
Financial Instrument [Axis]
Two Thousand Twenty Stock Option and Incentive Plan [Member]
Two thousand twenty stock option and incentive plan.
2020 Plan [Member]
Current assets:
Assets, Current [Abstract]
Fair Value, Inputs, Level 3 [Member]
Level 3 [Member]
Segment Reporting [Abstract]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Fair Value Assets and Liabilities Measured on Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Related Party Transactions [Abstract]
Commitments and contingencies (Note 13)
Commitments and Contingencies
Asset under Construction [Member]
Assets Under Construction [Member]
General and Administrative Expense [Member]
Total operating lease liabilities
Operating Lease, Liability
Operating lease liability
Total operating lease liabilities
Sale of Stock, Percentage of Ownership after Transaction
Beneficial owner holding percentage
Milestone Payments
Milestone Payments
Milestone payments.
Stockholders' Equity, Reverse Stock Split
Description of reverse stock spilt
Common Stock, No Par Value
Common Stock Par Value
US Treasury Bill Securities [Member]
Treasury Bills [Member]
Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract]
Cash flows (used in) provided by financing activities
Lessee, Lease, Description [Table]
Eli Lilly Collaboration Agreement [Member]
Eli Lilly Collaboration Agreement [Member]
Unaudited interim financial information
Unaudited Interim Financial Information [Policy Text Block]
Unaudited Interim Financial Information [Policy Text Block]
Purchases of property and equipment included in accounts payable
Capital Expenditures Incurred but Not yet Paid
Nonvoting Common Stock [Member]
Class A Nonvoting Common Stock
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Lease Contractual Term [Domain]
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic
Weighted-average number of common stock used in net loss per share, basic
Second Lease Extension
Second Lease Extension [Member]
Second Lease Extension [Member]
Document Information [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value, vested and exercisable
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Segments [Axis]
Long-Lived Tangible Asset [Domain]
Related party transactions
Related Party Transactions Disclosure [Text Block]
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
Equity, Attributable to Parent
Total stockholders' deficit
Beginning Balance
Ending Balance
Total stockholders' equity (deficit)
Preferred Stock, Par or Stated Value Per Share
Undesignated preferred stock, par value
Basis of Accounting, Policy [Policy Text Block]
Basis of presentation and consolidation
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Series A-1 Preferred Stock [Member]
Series A-1 Preferred Stock [Member]
Series A-1 Preferred Stock
Series A Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock [Member]
Series A-1 Preferred Stock
Over-Allotment Option [Member]
Over Allotment
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Selling and Marketing Expense [Member]
Sales milestones
Fair Value Disclosures [Text Block]
Fair value measurements
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Schedule of Stock-Based Compensation Expense
Project [Axis]
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Segment Reporting, Other Segment Item, Amount
Other segment items
Plan Name [Domain]
Deferred Offering Costs Included In Accrued Expenses
Deferred Offering Costs Included In Accrued Expenses
Deferred Offering Costs Included In Accrued Expenses
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity Address, City or Town
Other Commitments [Axis]
Nature Of Business [Abstract]
Nature Of Business [Abstract]
Number of Reportable Segments
Number of Reportable Segments
Security Exchange Name
Property, Plant and Equipment, Gross
Total property and equipment
Number of options unvested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Antidilutive Securities, Name [Domain]
Stockholders' Equity Note [Abstract]
Series Seed Redeemable Convertible Preferred Stock [Member]
Series Seed Redeemable Convertible Preferred Stock [Member]
Series Seed redeemable convertible preferred stock
Lease Amendment
Lease Amendment [Member]
Lease Amendment [Member]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation, Total
Cash, cash equivalents and restricted cash equivalents at beginning of period
Cash, cash equivalents and restricted cash equivalents at end of period
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Assets, Current
Total current assets
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of options vested and exercisable
Statement of Financial Position [Abstract]
Series Seed Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock
Antidilutive Security, Excluded EPS Calculation [Table]
Class of Stock [Axis]
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Number of securities in gross unrealized positions
Compensation and Employee Benefit Plans [Text Block]
Employee Benefit Plans
Liabilities
Total liabilities
Financial Instruments [Domain]
Deferred revenue
Increase (Decrease) in Deferred Revenue
Discovery and Development [Member]
Discovery and development.
Discovery and development
Computer software [Member]
Computer software
Computer Software [Member]
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Restricted Stock [Member]
Unvested restricted stock
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions
Number of securities in gross unrealized position for greater than 12 months
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average number of common stock used in net loss per share, diluted
Entity File Number
Entity File Number
Unrealized loss on marketable securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Other assets
Other Assets
Other Assets, Total
Cover [Abstract]
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Investments [Domain]
US Treasury Securities [Member]
US Treasury Securities [Member]
Treasury Bills [Member]
Number of Operating Segments
Number of Operating Segments
Exercise of Preferred Stock Warrants
Exercise of Preferred Stock Warrants
Exercise of Preferred Stock Warrants
Sale of Stock [Domain]
Professional and Contract Services Expense
Consulting and contractor
Professional and consulting
Segment Reporting Disclosure [Text Block]
Segment information
General and Administrative Expense
General and administrative
General and Administrative
Series B Preferred Stock [Member]
Series B Preferred Stock
Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract]
Cash flows used in operating activities
Remeasurement Of Right Of-Use Asset And Lease Liability
Remeasurement Of Right Of-Use Asset And Lease Liability
Remeasurement of right-of-use asset and lease liability
Revenue recognized
Deferred Income, Revenue Recognized
Restricted Cash Equivalents
Restricted Cash Equivalents [Member]
Restricted Cash Equivalents Member
Accrued Interest
Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss
Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Total
License Agreements Disclosure Text Block
License Agreements Disclosure Text Block
License agreements
Weighted average exercise price, unvested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
New Accounting Pronouncements, Policy [Policy Text Block]
Recent accounting pronouncements not yet adopted
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of Maturity Analysis of Operating Lease Liabilities
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Stock Issued During Period, Shares, Conversion of Convertible Securities
Preferred stock converted into common stock
Conversion of preferred stock to common stock upon closing of initial public offering, Shares
Reconciliation Of Cash, Cash Equivalents And Restricted Cash Equivalents [Abstract]
Reconciliation Of Cash, Cash Equivalents And Restricted Cash Equivalents [Abstract]
Reconciliation of cash, cash equivalents and restricted cash equivalents
Depreciation
Depreciation, Total
Purchases Of Property And Equipment Included In Accrued Expenses
Purchases Of Property And Equipment Included In Accrued Expenses
Purchases of property and equipment included in accrued expenses
First Lease Extension
First Lease Extension [Member]
First Lease Extension [Member]
Lessee, Operating Lease, Term of Contract
Operating Lease Term
Reportable Segment, Aggregation before Other Operating Segment [Member]
Operating Segment [Member]
Common Stock, Shares, Outstanding
Common Stock , shares outstanding
Common stock outstanding
Ending Balance, Shares
Beginning Balance, Shares
Restricted Cash Equivalent, Noncurrent
Long-term restricted cash equivalents
Restricted cash equivalents
Operating lease liabilities, current portion
Operating Lease, Liability, Current
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Depreciation and amortization
Document Transition Report
Document Transition Report
Operating Expenses
Total operating expenses
Research and Development Expense
Research and Development Expense, Total
Research and development
Total Net Sales
Total Net Sales
Total payment as a percetage of net sales
Lessee, Operating Leases [Text Block]
Leases
Revenue Recognition and Deferred Revenue [Abstract]
Statement of Cash Flows [Abstract]
Stock Issued During Period, Value, New Issues
Issuance of common stock from initial public offering, net of issuance costs
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
Stockholders' deficit
Equity [Text Block]
Earnings Per Share [Text Block]
Net loss per share
Computer Equipment [Member]
Computer Equipment [Member]
Net loss
Net loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value outstanding, beginning balance
Aggregate intrinsic value outstanding, ending balance
Operating Lease, Cost
Operating lease cost
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Two Two Five Ac Ac AKY Two Five One Nine [Member]
Two Two Five Ac Ac AKY Two Five One Nine.
[225Ac]Ac-AKY-2519
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Total Intrinsic Value
Assets [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Series A-1 Redeemable Convertible Preferred Stock [Member]
Series A-1 Redeemable Convertible Preferred Stock [Member]
Series A-1 redeemable convertible preferred stock
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Net amortization of premiums and accretion of discounts on investments in marketable securities
Amortization of Debt Issuance Costs and Discounts
Amortization of Debt Issuance Costs and Discounts, Total
Document Fiscal Year Focus
Document Fiscal Year Focus
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows provided by investing activities
Retirement Benefits [Abstract]
Accounts Payable, Current
Accounts Payable, Current, Total
Accounts payable
Research and Development Expense [Member]
Research And Development
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Marketable securities
Components Of Lease Costs [Table Text Block]
Components of lease costs
Schedule of Components of Lease Costs
Other assets
Increase (Decrease) in Other Noncurrent Assets
Upfront Payments
Upfront Payments
Nonrefundable upfront cash payment
Reduce Value Of Issued Share
Reduce Value Of Issued Share
Reduce value of issued share
Proceeds from exercise of common stock options
Proceeds from Stock Options Exercised
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Entity Legal Form
Royalty Transfer Agreement [Member]
Royalty Transfer Agreement [Member]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Net Income (Loss) Available to Common Stockholders, Basic
Net Income (Loss) Available to Common Stockholders, Basic, Total
Net loss attributable to common stockholders, basic
Lessee, Operating Lease, Liability, to be Paid, after Year Five
2031 and beyond
Share-Based Payment Arrangement [Abstract]
Unrecognized compensation related to unvested stock
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Assets, Fair Value Disclosure
Assets, Fair Value Disclosure, Total
Financial Assets
Sale of Stock [Axis]
Revenues
Revenues, Total
Collaboration revenue
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by investing activities
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Money Market Funds [Member]
Money market funds [Member]
Income Tax Disclosure [Text Block]
Income taxes
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Redeemable convertible preferred stock , shares issued
Temporary Equity, Shares Issued
Document Information [Table]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Property, Plant and Equipment [Table Text Block]
Property and equipment, net
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, Outstanding at the end of the period
Weighted average exercise price, Outstanding at the beginning of the period
License Agreement
Entertainment, License Agreement for Program Material [Abstract]
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Unrecognized Tax Benefits
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Uncertain tax positions
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Cash paid for amounts included in the measurement of operating lease liabilities
Cash Paid For Amounts Included In The Measurement Of Operating Lease Liabilities
Cash Paid For Amounts Included In The Measurement Of Operating Lease Liabilities
Measurement Frequency [Domain]
Statement of Income Location, Balance [Axis]
Trading Symbol
Trading Symbol
Remeasurement Of Right-Of-Use Asset And Lease Liability Due To Lease Modification
Remeasurement Of Right-Of-Use Asset And Lease Liability Due To Lease Modification
Remeasurement of right-of-use asset and lease liability due to lease modification
Property and equipment, net
Property, Plant and Equipment Disclosure [Text Block]
Related Party Transaction [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Fair Value, Recurring [Member]
Fair value recurring [Member]
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total undiscounted lease payments
Less: imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Equity Components [Axis]
MPM Asset Management LLC [Member]
MPM Asset Management LLC
MPM Asset Management LLC
Research and Development Expense (Excluding Acquired in Process Cost)
External research and development
External research and development
Nonoperating Income (Expense)
Total other income, net
Equity Component [Domain]
Asset Class [Axis]
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Deferred revenue, net of current portion
IPO
IPO [Member]
Maximum [Member]
Maximum [Member]
Schedule of Stock by Class [Table Text Block]
Schedule of Common Stock Available for Future Issuance
Statistical Measurement [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted average exercise price, Exercised
Common stock value
Common Stock, Value, Issued
Information Technology, Facilities, Office and Other
Information technology, facilities, office and other.
Information technology, facilities, office and other
Net Income (Loss) Available to Common Stockholders, Diluted
Net Income (Loss) Available to Common Stockholders, Diluted, Total
Net loss attributable to common stockholders, diluted
Partner Preferred Stock [Member]
Partner Preferred Stock [Member]
Partner Preferred Stock
Equipment [Member]
Laboratory Equipment [Member]
Schedule of Basic And Diluted Net Loss Per Share Attributable To Common Stockholders
Schedule of Weighted Average Number of Shares [Table Text Block]
Marketable Securities [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Preferred Stock, Shares Authorized
Preferred stock authorized
Preferred stock, shares undesignated
Comprehensive Income (Loss), Net of Tax, Attributable to Noncontrolling Interest
Comprehensive loss
Comprehensive loss
Collaboration Revenue [Text Block Item]
Collaboration Revenue [Text Block Item]
Collaboration revenue
Related party transaction description
Related Party Transaction, Description of Transaction
Related Party Transaction [Line Items]
Entity Registrant Name
Entity Registrant Name
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total
Uncertain tax positions, accrued interest or penalties
Unrealized Loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Unrealized Loss
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total
Transfers
Other expense, net
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Measurement Frequency [Axis]
Issuance costs
Proceeds from Issuance of Common Stock
Sublease Agreement
Sublease Agreement [Member]
Sublease Agreement [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Deferred Revenue, Revenue Recognized
Collaboration recognized revenue
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive (loss) income
Revenue from Collaborative Arrangement, Excluding Revenue from Contract with Customer
Collaboration revenue
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Assets
Total assets
Property, Plant and Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted average remaining contractual life, exercisable
Income Statement [Abstract]
Defined Benefit Plan [Abstract]
General And Administrative Includes Related Parties
General And Administrative Includes Related Parties
General and administrative includes related parties
Preferred Stock, No Par Value
Stock Issued During Period, Shares, New Issues
Number of shares issued
Issuance of common stock from initial public offering, net of issuance costs, Shares
Temporary Equity, Shares Authorized
Redeemable convertible preferred stock , shares authorized
Stock Options Outstanding [Member]
Stock Options Outstanding [Member]
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net loss per share of common stock, diluted
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Significant Segment Expenses
Dividends, Common Stock
Dividends, Common Stock, Total
Dividends declared or paid
City Area Code
2026 Equity Incentive Plan [Member]
Two Thousand Twenty Six Equity Incentive Plan [Member]
Two thousand twenty six equity incentive plan.
Variable Lease, Cost
Variable lease cost
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term (in years)
Segment Reporting Information [Line Items]
Reverse Stock Split conversion ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Lease Expiration Date
Termination Date
Lease, Cost
Total lease cost
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Denominator [Abstract]
Denominator [Abstract]
Denominator:
Total cash, cash equivalents and restricted cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation, Ending Balance
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation, Beginning Balance
Restricted cash equivalents
Operating Income (Loss)
Loss from operations
Payments for Annual Global Net Sales
Payments for Annual Global Net Sales
Payment as a percentage of annual global net sales to each charity foundation
Retained Earnings [Member]
Accumulated Deficit [Member]
Share-Based Payment Arrangement, Noncash Expense
Total stock-based compensation expense
Stock-based compensation
Adjusted Transaction Price
Adjusted Transaction Price
Adjusted transaction price
Payments of Stock Issuance Costs
Payment of offering costs
Liquidity Policy
Liquidity Policy
Liquidity
Series Seed Preferred Stock [Member]
Series Seed Preferred Stock [Member]
Series Seed Preferred Stock
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by (used in) financing activities
Temporary Equity Conversion of Redeemable Convertible Preferred Stock to Common Stock Upon Closing of Initial Public Offering Value
Temporary equity conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering value.
Conversion of preferred stock to common stock upon closing of initial public offering
Nonoperating Income (Expense) [Abstract]
Other income (expense):
Marketable Securities [Table Text Block]
Schedule of Marketable Debt Securities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Dilutive Securities Excluded From the Computation Of Diluted Net Loss Per Share Attributable To Common Stockholders
Corporate Debt Securities [Member]
Corporate Debt Securities [Member]
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings
Change in fair value
Entity Tax Identification Number
Entity Tax Identification Number
Equity, Including Portion Attributable to Noncontrolling Interest [Abstract]
Redeemable convertible preferred stock:
Revenues [Abstract]
Revenue:
Marketable Security, Unrealized Gain (Loss)
Net unrealized loss on marketable securities
Net unrealized loss on marketable securities held
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Noncontrolling Interest [Abstract]
Local Phone Number
Related Party Transaction [Domain]
Accounting Policies [Abstract]
Revenue from Contract with Customer, Excluding Assessed Tax
Upfront Milestone Payments
General and Administrative Expense [Abstract]
General and administrative expenses:
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Commercial Paper [Member]
Commercial Paper [Member]
Labor and Related Expense
Employee-related
Employee-related (including stock-based compensation)
Employee-related (including stock-based compensation)
Common stock available for future grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Unrecognized compensation cost non-vested options to be recognized, period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Office Equipment [Member]
Office Equipment & Furniture [Member]
Accrued Professional Fees, Current
Accrued professional costs
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Cash, cash equivalents and marketable securities
Increase (Decrease) in Accrued Expenses and Other Current Liabilities
Increase (decrease) in accrued expenses and other current liabilities.
Accrued expenses and other current liabilities
Stock, Class of Stock [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company
Weighted average remaining contractual life, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term