75000 - Document - Document and Entity Information
link:presentationLink
link:calculationLink
link:definitionLink
75010 - Statement - Condensed Consolidated Balance Sheets (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75020 - Statement - Condensed Consolidated Balance Sheets (Unaudited) (Parenthetical)
link:presentationLink
link:calculationLink
link:definitionLink
75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75040 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75050 - Statement - Condensed Consolidated Statements of Stockholders' Equity (Unaudited) (Parenthetical)
link:presentationLink
link:calculationLink
link:definitionLink
75060 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
995455 - Disclosure - Overview and Basis of Presentation
link:presentationLink
link:calculationLink
link:definitionLink
995465 - Disclosure - Summary of Significant Accounting Policies
link:presentationLink
link:calculationLink
link:definitionLink
995485 - Disclosure - Fair Value Measurements
link:presentationLink
link:calculationLink
link:definitionLink
995495 - Disclosure - Accrued Expenses
link:presentationLink
link:calculationLink
link:definitionLink
995505 - Disclosure - Commitments and Contingencies
link:presentationLink
link:calculationLink
link:definitionLink
995515 - Disclosure - Collaborations and Other Arrangements
link:presentationLink
link:calculationLink
link:definitionLink
995525 - Disclosure - Investments and Other Assets
link:presentationLink
link:calculationLink
link:definitionLink
995535 - Disclosure - Rewrite Acquisition
link:presentationLink
link:calculationLink
link:definitionLink
995545 - Disclosure - Leases
link:presentationLink
link:calculationLink
link:definitionLink
995555 - Disclosure - Stock-Based Compensation
link:presentationLink
link:calculationLink
link:definitionLink
995565 - Disclosure - Loss Per Share
link:presentationLink
link:calculationLink
link:definitionLink
995575 - Disclosure - Stockholders’ Equity
link:presentationLink
link:calculationLink
link:definitionLink
995585 - Disclosure - Segment Information
link:presentationLink
link:calculationLink
link:definitionLink
995595 - Disclosure - Subsequent Events
link:presentationLink
link:calculationLink
link:definitionLink
995605 - Disclosure - Summary of Significant Accounting Policies (Policies)
link:presentationLink
link:calculationLink
link:definitionLink
995625 - Disclosure - Fair Value Measurements (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995635 - Disclosure - Accrued Expenses (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995645 - Disclosure - Collaborations and Other Arrangements (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995655 - Disclosure - Investments and Other Assets (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995665 - Disclosure - Leases (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995675 - Disclosure - Rewrite Acquisition (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995685 - Disclosure - Stock-Based Compensation (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995695 - Disclosure - Loss Per Share (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995705 - Disclosure - Stockholders’ Equity (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995715 - Disclosure - Segment Information (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995725 - Disclosure - Overview and Basis of Presentation - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995755 - Disclosure - Fair Value Measurements - Summary of Financial Assets Recognized at Fair Value on Recurring Basis (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995765 - Disclosure - Fair Value Measurements - Additional information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995775 - Disclosure - Fair Value Measurements - Schedule of Change in Fair Value of the Contingent Consideration Liabilities (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995785 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995795 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail) 2
link:presentationLink
link:calculationLink
link:definitionLink
995805 - Disclosure - Accrued Expenses - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995815 - Disclosure - Commitments and Contingencies (Additional Information) (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995825 - Disclosure - Collaborations and Other Arrangements - Summary of Changes in Accounts Receivable and Contract Liabilities (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995835 - Disclosure - Collaborations and Other Arrangements - Summary of Revenues Recognized Resulting from Changes in Contract Liability Balance (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995845 - Disclosure - Collaborations and Other Arrangements - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995855 - Disclosure - Investments and Other Assets - Schedule of Investments and Other Assets (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995865 - Disclosure - Investments and Other Assets - Schedule of Investments and Other Assets (Detail) 2
link:presentationLink
link:calculationLink
link:definitionLink
995875 - Disclosure - Investments and Other Assets - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995885 - Disclosure - Rewrite Acquisition - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995895 - Disclosure - Rewrite Acquisition - Summary of Transaction Price Determined and Allocated (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995905 - Disclosure - Leases - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995915 - Disclosure - Leases - Schedule of Reconciliation of Undiscounted Cash Flows for Operating Lease Liabilities / Future Minimum Lease Payments (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995925 - Disclosure - Leases - Schedule of Reconciliation of Undiscounted Cash Flows for Operating Lease Liabilities / Future Minimum Lease Payments (Detail) 2
link:presentationLink
link:calculationLink
link:definitionLink
995935 - Disclosure - Stock-Based Compensation - Schedule of Stock-Based Compensation Expense (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995945 - Disclosure - Stock-Based Compensation - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995955 - Disclosure - Stock-Based Compensation - Summary of Restricted Stock Activity (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995965 - Disclosure - Stock-Based Compensation - Summary of Weighted Average Assumptions Used to Compute Fair Value of Option Granted (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995975 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995985 - Disclosure - Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
995995 - Disclosure - Loss Per Share - Potential Dilutive Securities Excluded from Computation of Diluted Net Loss Per Common Share (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
996005 - Disclosure - Stockholders' Equity - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
996015 - Disclosure - Segment Information - Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
996025 - Disclosure - Segment Information - Schedule Of Segment Reporting (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
996035 - Disclosure - Segment Information - Schedule Of Segment Reporting (Parenthetical) (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
996045 - Disclosure - Subsequent Event Additional Information (Detail)
link:presentationLink
link:calculationLink
link:definitionLink
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value per Share, Vested
Total fair value amount, Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value Amount
Share based compensation arrangement by share based payment award equity instruments other than options vested in period weighted average grant date fair value amount.
Long Term Portion of Restricted Cash Equivalents
Long term portion of restricted cash equivalents.
Restricted cash equivalents, long-term
Tech Square Lease [Member]
Tech Square Lease [Member]
Tech square lease.
Accrued construction costs.
Accrued Construction Costs
Accrued construction costs
Discount rate
Discount rate
Market awards.
Market Awards [Member]
Market Awards [Member]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Balance
Balance
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase (Decrease) in Accounts Payable
Rewrite Merger Agreement [Member]
Rewrite merger agreement member.
Rewrite Holders
Business combination transaction price.
Business Combination Transaction Price Abstract
Transaction Price
Plan Name
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, shares authorized
Common Stock, Shares Authorized
Costs to obtain or fulfill contract capitalized
Capitalized Contract Cost, Gross
Accounts Receivable, after Allowance for Credit Loss, Total
Accounts Receivable, after Allowance for Credit Loss
Accounts receivable
Product and Service
Product and Service [Axis]
Fair Value by Liability Class [Domain]
Document Fiscal Period Focus
Document Fiscal Period Focus
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Entity Shell Company
Other Accrued Liabilities, Current
Accrued other
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and cash equivalents
Cash and Cash Equivalent
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Common Stock, Shares, Issued, Total
Common stock, shares issued
Common Stock, Shares, Issued
Statement [Table]
Statement [Table]
Weighted average grant date fair value per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Percentage of fair market value of common stock
Investment Owned, Balance, Principal Amount
Statement [Line Items]
Statement [Line Items]
Collaboration term extension period.
Collaboration Term Extension Period
Collaboration term extension period
Business Combination [Domain]
Entity Filer Category
Entity Filer Category
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Service awards.
Service Awards [Member]
Service Awards [Member]
Payments to Acquire Marketable Securities, Total
Purchases of marketable securities
Payments to Acquire Marketable Securities
Weighted Average Exercise Price per Share, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Prepaid Expenses and Other Current Assets [Member]
Investments that matured beyond five years
Available For Sales Securities Noncurrent Maturing Beyond Year Five
Available-for-sales securities, noncurrent, maturing beyond year five.
Amended Two Thousand Twenty Two Sales Agreement [Member]
Amended Two Thousand Twenty Two Sales Agreement [Member]
Amended 2022 Sales Agreement [Member]
Deferred Revenue [Domain]
Cash equivalents and restricted cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Regeneron Agreement [Member]
Regeneron Arrangement [Member]
Regeneron arrangement.
Public offering price per share
Common stock price per share
Shares Issued, Price Per Share
Interest income
Interest income
Investment Income, Interest
CambridgeMember
Cambridge [Member]
Cambridge [Member]
Geographical
Geographical [Domain]
Other Asset Backed Securities [Member]
Asset-Backed Securities [Member]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Table]
Prepaid Expense and Other Assets, Noncurrent
Prepaid expenses and other assets, long-term
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional paid-in capital
Additional Paid in Capital, Common Stock
Albany Lease [Member]
Albany Lease [Member]
Albany Lease.
Related Party [Member]
Related Party [Member]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Restricted cash equivalents, long-term
Restricted Cash Equivalents, Total
Restricted Cash Equivalent
Restricted cash equivalents, included in prepaid expenses and other current assets,and investments and other assets
Business combination upfront cash consideration.
Business Combination Upfront Cash Consideration
Upfront cash consideration
Vesting
Vesting [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of options, Granted
Business combination research contingent consideration liabilities.
Business Combination Research Contingent Consideration Liabilities
Research contingent consideration liabilities
Schedule of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
ReCode Therapeutics, Inc.
ReCode Therapeutics Inc.
ReCode Therapeutics Inc [Member]
Net loss per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Number of Options, Outstanding, Beginning Balance
Number of Options, Outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Total current liabilities
Liabilities, Current
Accounts receivable
Increase (Decrease) in Accounts Receivable
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Pre-specified Research Milestones [Member]
Prespecified Research Milestones Member
Pre-specified research milestones.
Consolidation Items [Domain]
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Reduction of employee headcount
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Accounts receivable, Additions
Increase In Accounts Receivables
Increase in accounts receivables.
Entity Small Business
Entity Small Business
Increase (Decrease) in Accrued Liabilities, Total
Increase (Decrease) in Accrued Liabilities
Accrued expenses
Rewrite [Member]
Rewrite Therapeutics, Inc. [Member]
Rewrite Therapeutics, Inc.
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Number of options, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Total intrinsic value of stock options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Increase Decrease In Operating Right Of Use Assets
Increase (decrease) in operating right of use assets.
Operating lease right-of-use assets
Share-Based Payment Arrangement [Text Block]
Stock-Based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Collaboration agreement extension period
Collaboration agreement further option extension period.
Collaboration Agreement Further Option Extension Period
Collaboration agreement further option extension period
Leases [Abstract]
Contract with Customer, Liability, Total
Deferred revenue
Deferred revenue, Balance at Beginning of Period
Deferred revenue, Balance at End of Period
Contract with Customer, Liability
Lessee Lease Description [Line Items]
Lessee, Lease, Description [Line Items]
Amendment Flag
Amendment Flag
Product and Service
Product and Service [Domain]
Research milestones
Research milestones payment liability
Research milestones payment liability.
LIABILITIES AND STOCKHOLDERS’ EQUITY
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock [Member]
Common Stock
Weighted Average Exercise Price per Share, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
2029
Lessee, Operating Lease, Liability, to be Paid, Year Three
Other segment information
Other Operating Income (Expense), Net
Other (income) expense, net
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Entity Address, Address Line One
Entity Address, Address Line One
Summary of Weighted Average Assumptions Used to Compute Fair Value of Option Granted
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Marketable Securities [Table]
Marketable Securities [Table]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
Supplemental Cash Flow Information [Abstract]
Upfront consideration payable in cash
Upfront consideration payable in cash
Upfront Consideration Payable In Cash
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Rule 10B51 Trading Plan [Member]
Rule 10B51 Trading Plan.
Business Combination, Contingent Consideration [Line Items]
Other comprehensive loss - unrealized loss on marketable securities
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Other comprehensive income (loss) - unrealized gain (loss) on marketable securities
Document Type
Document Type
Nex-z [Member]
Nex-z [Member]
Nex-z
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Investments, Debt and Equity Securities [Abstract]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net decrease in cash, cash equivalents and restricted cash equivalents
Potential dilutive securities excluded from computation of diluted net loss per common share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Common stock, par value
Common Stock, Par or Stated Value Per Share
First Anniversary of Original Vesting Date [Member]
Share-Based Payment Arrangement, Tranche One [Member]
Weighted Average Remaining Contractual Term, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Expected volatility of underlying stock, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-sale, Total
Estimated Fair Value
Debt Securities, Available-for-Sale
Financial Institution Debt Securities [Member]
Financial Institution Debt Securities [Member]
Financial institution debt securities.
Schedule of Changes in Stockholders’ Equity
Schedule of Stockholders Equity [Table Text Block]
Realized gains or losses on marketable securities
Realized Investment Gains (Losses)
Realized Investment Gains (Losses), Total
Number of options, Exercised
Exercise of stock options, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Milestone payments
Development based milestone payments under agreement
Development Based Milestone Payments Under Agreement
Aggregate potential clinical development milestone payments available to be earned under a collaboration arrangement for each available target selected by the collaborator.
Accrued research and development
Accrued Research And Development Expenses Current
Accrued research and development expenses current.
Winter Street and Tech Square Lease [Member]
Winter street and tech square lease.
Winter Street and Tech Square Lease [Member]
Accrued Liabilities, Current
Total accrued expenses
Accrued expenses
Accrued expenses
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Hemophilia Co Co Agreements
Hemophilia Co Co Agreements [Member]
Hemophilia Co/Co agreements.
Document Quarterly Report
Document Quarterly Report
Legal accounting and other fees
Legal Accounting And Other Fees
Legal, accounting and other fees.
Entity Address, State or Province
Entity Address, State or Province
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]
Organization consolidation and presentation of financial statements disclosure.
Number of Shares, Unvested, Beginning balance
Number of Shares, Unvested, Ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Unvested restricted stock units
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Shares available for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Indicated equity volatility
Indicated Equity Volatility
Indicated equity volatility.
Geographical
Geographical [Axis]
Amounts included in the contract liability at the beginning of the period
Contract with Customer, Liability, Revenue Recognized
Marketable Securities, Current, Total
Marketable securities
Marketable Securities, Current
Contract liabilities:
Contract with Customer, Liability [Abstract]
Contingent consideration paid to Rewrite Holders
Contingent Consideration Paid to Rewrite Holders
Contingent consideration paid to rewrite holders.
Contingent consideration paid
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Stock-Based Compensation Expense
Exercise of stock options
Stock Issued During Period, Value, Stock Options Exercised
Collaborations and Other Arrangements
Collaborative Arrangement Disclosure [Text Block]
Nature of Expense [Axis]
Sales and maturities of marketable securities
Proceeds from Sale and Maturity of Marketable Securities, Total
Proceeds from Sale and Maturity of Marketable Securities
Liability for milestone payment
Liability for milestone payment.
Liability For Milestone Payment
Deferred Revenue Arrangement Type [Axis]
Antidilutive Securities
Antidilutive Securities [Axis]
Deferred revenue, Additions
Contract with Customer, Liability, Cumulative Catch-up Adjustment to Revenue, Change in Measure of Progress
Type of Revenue [Extensible List]
Revenue, Product and Service [Extensible Enumeration]
Business combination transaction price allocated.
Business Combination Transaction Price Allocated Abstract
Transaction Price Allocated
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Research and Development Services [Member]
Research And Development Services [Member]
Research and development services.
Tenant Improvement Allowance Per Square Foot
Tenant improvement allowances per square foot.
Tenant improvement allowances per square foot
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Other Comprehensive Income (Loss)
Cash
Cash [Member]
Cash and Cash Equivalents [Domain]
Summary of Revenues Recognized Resulting from Changes in Contract Liability Balance
Revenue From Contract With Customer Table [Text Block]
Revenue from contract with customer.
AvenCell Co Co agreement.
AvenCell Co Co Agreement [Member]
Collaboration agreement payment made
Business Combination, Consideration Transferred
Total transaction price
Total consideration
Lessee, Operating Lease, Option to Extend
Operating lease, options to extend
Operating lease, options to extend
Investments and Other Noncurrent Assets [Text Block]
Investments and Other Assets
Minimum
Minimum [Member]
Minimum [Member]
Weighted Average Grant Date Fair Value per Share, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Segment Reporting [Abstract]
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets, Total
Business Combination, Recognized Asset Acquired, Asset
Other current assets acquired
Other Research And Development [Member]
Other Research And Development [Member]
Other Research And Development [Member]
Interim Period, Costs Not Allocable [Domain]
Summary of Financial Assets Recognized at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Liabilities, Current [Abstract]
Current liabilities:
Seventh Floor Component [Member]
7th floor component.
7th Floor Component [Member]
Variable Consideration [Member]
Variable consideration.
Variable Consideration [Member]
Accounts receivable, Balance at End of Period
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable, Balance at Beginning of Period
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable, related party
Accounts receivable
Commitments and contingencies (Note 6)
Commitments and Contingencies
Commitments and contingent payments
Weighted Average Grant Date Fair Value per Share, Unvested, Beginning balance
Weighted Average Grant Date Fair Value per Share, Unvested, Ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
General and Administrative [Member]
General and Administrative Expenses [Member]
General and Administrative Expense [Member]
Total operating lease liabilities at March 31, 2026
Operating Lease, Liability
Lease liability
Sparing Vision [Member]
Sparing Vision [Member]
Sparing Vision [Member]
SparingVision SAS [Member]
Marketable Securities, Noncurrent, Total
Marketable securities - noncurrent
Marketable Securities, Noncurrent
Two thousand twenty two sales agreement.
Two Thousand Twenty Two Sales Agreement [Member]
2022 Sales Agreement [Member]
Operating lease liabilities
Increase Decrease In Operating Lease Liabilities
Increase (decrease) in operating lease liabilities.
Winter street lease member.
Winter Street Lease [Member]
Winter Street Lease [Member]
Winter Street Lease [Member]
Lessee Lease Description [Table]
Lessee, Lease, Description [Table]
Preferred Stock Return Percentage
Preferred stock return percentage.
Preferred stock return percentage
Purchases of property and equipment unpaid at period end
Capital Expenditures Incurred but Not yet Paid
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Consolidated net loss
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Cash acquired
Pre-specified research milestones contingent payment
Pre Specified Research Milestones Contingent Payment
Pre specified research milestones contingent payment.
Loss Contingencies [Table]
Weighted average shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Aggregate Intrinsic Value, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Business combination transaction price.
Business Combination Transaction Price
Total transaction price
Total transaction price
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Investment Company, Return Value
Investment company, return value.
Investment company return value
Subsequent Events [Text Block]
Subsequent Event
Performance based awards.
Performance Based Awards [Member]
Performance Based Awards [Member]
Cash, Beginning Balance
Cash, Ending Balance
Cash
Cash
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Equity-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
Total stockholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Number of Shares, Cancelled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Cancelled In Period
Share based compensation arrangement by share based payment award equity instruments other than options cancelled in period.
Statement of Stockholders' Equity [Abstract]
Regulatory Approval Milestone [Member]
Regulatory Approval Milestone Member
Regulatory approval milestone.
Equity Method Investment [Table]
Business acquisition cost of acquired entity transaction cost.
Business Acquisition Cost Of Acquired Entity Transaction Cost
Transaction costs
Two Thousand And Twenty Five Stock Option And Incentive Plan [Member]
Two thousand and twenty five stock option and incentive plan.
2025 Plan [Member]
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Measurements
Fair Value Disclosures [Text Block]
Schedule of Reconciliation of Undiscounted Cash Flows for Operating Lease Liabilities / Future Minimum Lease Payments
Finance Lease, Liability, to be Paid, Maturity [Table Text Block]
Investment Owned, Fair Value, Beginning Balance
Investment Owned, Fair Value, Ending Balance
Investment Owned, Fair Value
Investment Owned, Fair Value
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses
Performance based awards with TSR multiplier.
Performance Based Awards with TSR Multiplier [Member]
Performance Based Awards with TSR Multiplier [Member]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Plan Name
Plan Name [Domain]
Increase (Decrease) in Other Operating Assets, Total
Other assets
Increase (Decrease) in Other Operating Assets
Payment of contingent consideration
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Change in fair value
Contingent Consideration Classified as Equity, Fair Value Disclosure
Change in fair value of contingent consideration
Change in fair value of contingent consideration
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Related and Nonrelated Parties [Axis]
Entity Address, City or Town
Entity Address, City or Town
Contingent payments
Business Combination, Contingent Consideration, Liability
Business Combination, Contingent Consideration, Liability, Total
Number of reportable segment
Number of Reportable Segments
Security Exchange Name
Security Exchange Name
Business combination, recognized identifiable assets acquired and liabilities assumed, In-process research and development.
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed In Process Research And Development
In-process research and development
Investments, All Other Investments [Abstract]
Prepaid Rent
Prepaid Rent
Prepaid rent Tech Square Lease, long-term
Counterparty Name
Counterparty Name [Axis]
Operating lease, description
Operating lease, description
Lessee, Operating Lease, Lease Not yet Commenced, Description
Compensation Related Costs [Abstract]
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Executive Officer [Member]
Senior Executives [Member]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement
Statistical Measurement [Domain]
Total current assets
Assets, Current
Equity-based compensation expense
Share-Based Payment Arrangement, Expense
Stock-based compensation
Document Period End Date
Document Period End Date
Operating Lease Percentage Of Annual Increase
Operating lease percentage of annual increase.
Percentage of annual increase
Operating lease percentage of annual increase
Title and Position [Axis]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Number of Options, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Accounts receivable:
Accounts Receivable, after Allowance for Credit Loss [Abstract]
Contingent consideration shares paid to rewrite holders
Contingent Consideration Shares Paid to Rewrite Holders
Contingent consideration paid, shares
Statement of Financial Position [Abstract]
RSUs [Member]
Restricted Stock Units (RSUs) [Member]
Unvested Restricted Stock Units [Member]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Vesting
Vesting [Axis]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Reconciliation of cash, cash equivalents and restricted cash equivalents to condensed consolidated balance sheet:
Number of remaining shares eligible for sale under agreement value.
Proceeds from common stock offering
Number Of Remaining Shares Eligible For Sale Under Agreement Value
Liabilities
Total liabilities
Available For Sales Securities Non Current Maturity Period
Available-for-sales Securities, non-current, maturity period
Available-for-sales securities, non-current, maturity period.
Financial Instruments
Financial Instruments [Domain]
Percentage of gross proceeds from common stock as sales agent cash commission
Percentage Of Gross Proceeds From Common Stock As Sales Agent Cash Commission
Percentage of gross proceeds from common stock as sales agent cash commission.
Description of stock options granted under the Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Description
Share based compensation arrangements by share based payment award, Total shareholder return modifier.
Share Based Compensation Arrangements by Share Based Payment Award, Total Shareholder Return Modifier
TSR modifier
Other Comprehensive Income (Loss), Reclassification Adjustment from AOCI for Investment Transferred from Available-for-Sale to Equity Method, Tax
Other comprehensive income (loss) - unrealized gain on equity method investment
Reclassification of other comprehensive income (loss) - equity method investment
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest [Abstract]
Other comprehensive loss:
2028
Lessee, Operating Lease, Liability, to be Paid, Year Two
Restricted Stock [Member]
Restricted Stock [Member]
Weighted average shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Entity File Number
Securities Act File Number
Statement of Financial Position Location, Activity, Capitalization [Axis]
Cover [Abstract]
Expected volatility of underlying stock, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Co-Development and Co-Funding Agreement [Member]
Co-Development And Co-Funding Agreement [Member]
Co-Development And Co-Funding Agreement Member.
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Market offering as other current asset
Vesting of restricted stock units, shares
Stock Issued During Period Shares Vesting Restricted Units
Stock issued during period shares vesting restricted units.
Reduction of Right of Use Assets From Remeasurement of Lease Liabilities
Reduction of Right of Use Assets From Remeasurement of Lease Liabilities
Reduction of right-of-use assets from remeasurement of lease liabilities
Sale of Stock
Sale of Stock [Domain]
U.S. Treasury and Other Government - Backed Securities [Member]
U S Treasury And Other Government Backed Securities [Member]
U S Treasury and other government backed securities.
Segment Reporting Disclosure [Text Block]
Segment Information
Rule 10b 51 Arr Modified1 [Flag]
Rule 10b 51 Arr Modified1.
Rule 10b5-1 Arrangement Modified
General and Administrative Expense, Total
General and administrative
General and Administrative Expense
Lessee Operating Lease Rent Per Square Foot
Lessee operating lease rent per square foot.
Operating lease rent per square foot
Marketable securities:
Marketable Securities [Abstract]
Restructuring Charges
Restructuring Charges, Total
Restructuring Charges
Recent Accounting Pronouncements - Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Current portion of deferred revenue
Contract with Customer, Liability, Current
Deferred revenue current
Remaining vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
RSUs vesting period
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities, Total
Business Combination, Recognized Liability Assumed, Liability
Other liabilities assumed
Other liabilities assumed
NTLA Two Thousand Two [Member]
NTLA Two Thousand Two [Member]
NTLA-2002 [Member]
Risk-free interest rate, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Unrecognized equity-based compensation expense related to restricted stock
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unallocated Share Based Compensation Expense
Unallocated share based compensation expense.
Unallocated stock-based compensation expense
Common stock, shares outstanding
Beginning balance, shares
Ending balance, shares
Common Stock, Shares, Outstanding
Current portion of operating lease liability
Operating Lease, Liability, Current
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Depreciation, Depletion and Amortization, Total
Depreciation and amortization
Depreciation, Depletion and Amortization
Aggregate transaction price remaining to be recognized
Revenue, Remaining Performance Obligation, Amount
Document Transition Report
Document Transition Report
Research and Development Expense, Total
Research and Development Expense
Research and development
External development expenses
Leases
Lessee, Operating Leases [Text Block]
Statement of Cash Flows [Abstract]
BOH Expansion Premises Component [Member]
BOH expansion premises component.
BOH Expansion Premises Component [Member]
Issuance of common stock
Stock Issued During Period, Value, New Issues
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Assets, Fair Value Disclosure [Abstract]
Assets
Stockholders’ Equity
Equity [Text Block]
Loss Per Share
Earnings Per Share [Text Block]
Summary of Restricted Stock Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Net loss
Segment net loss
Aggregate Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
ASSETS
Assets [Abstract]
Area Of Space Leased Expandable
Area of space leased expandable.
Area of space leased expandable
Investment
Investments and Other Noncurrent Assets
Investments and other assets
Total investments and other assets
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Document Fiscal Year Focus
Document Fiscal Year Focus
At-the-market offerings.
At The Market Offerings [Member]
At The Market Offerings [Member]
At The Market Offerings [Member]
CASH FLOWS FROM INVESTING ACTIVITIES:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Research and Development Expense [Member]
Research and Development [Member]
Two thousand sixteen Regeneron Agreement.
Two Thousand Sixteen Regeneron Agreement [Member]
2016 Regeneron Agreement [Member]
Marketable Securities
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Schedule of Change in Fair Value of the Contingent Consideration Liabilities
Schedule of Changes in Fair Value of Plan Assets [Table Text Block]
Summary of Changes in Accounts Receivable and Contract Liabilities
Changes In Accounts Receivable And Contract Liabilities Table [Text Block]
Changes in accounts receivable and contract liabilities.
Schedule of Other Assets [Table Text Block]
Schedule of Investments and Other Assets
Lessee, Operating Lease, Lease Not yet Commenced, Term of Contract
Operating lease, term of contract
Operating lease, term of contract
Proceeds from Stock Options Exercised
Proceeds from option exercises unpaid at period end
Proceeds from options exercised
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
2027
Lessee, Operating Lease, Liability, to be Paid, Year One
Rewrite therapeutics telaware corporation [Member]
Rewrite Therapeutics Delaware Corporation [Member]
Rewrite Therapeutics Delaware Corporation Member
Two Thousand and Twenty Four Inducement Plan [Member]
Two thousand and twenty four inducement plan.
Inducement Plan [Member]
AvenCell
AvenCell [Member]
AvenCell [Member]
AvenCell Therapeutics, Inc. [Member]
Michael Dube [Member]
Michael Dube.
Michael Dube [Member]
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Thereafter
Share-Based Payment Arrangement [Abstract]
Research Materials Shippmet Services [Member]
Research materials shippmet services [member]
Research materials shippmet services.
Assets, Fair Value Disclosure
Total Assets
Total Assets
Share based compensation arrangements by share based payment award, performance shares.
Share Based Compensation Arrangements by Share Based Payment Award, Performance Shares
Performance shares
Sale of Stock
Sale of Stock [Axis]
Material costs
Cost, Direct Material
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by investing activities
Title of 12(b) Security
Title of 12(b) Security
Weighted Average Exercise Price per Share, Forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Lease Not yet Commenced, Option to Extend
Operating lease, option to extend
Related and Nonrelated Parties [Domain]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Remainder of 2026
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Consolidated Entities [Axis]
Reconciliation of Revenue from Segments to Consolidated [Table]
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Weighted Average Exercise Price per Share, Outstanding, Beginning Balance
Weighted Average Exercise Price per Share, Outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Business Combination [Text Block]
Rewrite Acquisition
Additional Paid-In Capital [Member]
Additional Paid-in Capital [Member]
Additional Paid-In Capital
Measurement Frequency
Measurement Frequency [Domain]
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Risk-free interest rate , Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
2016 Employee Stock Purchase Plan [Member]
Two Thousand And Sixteen Employee Stock Purchase Plan [Member]
2016 employee stock purchase plan.
Employee-related Liabilities, Current, Total
Employee compensation and benefits
Employee-related Liabilities, Current
CASH FLOWS FROM FINANCING ACTIVITIES:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term of options
Expected term
Fair Value on Recurring Basis [Member]
Fair Value, Recurring [Member]
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Schedule of Equity Method Investments [Line Items]
Lease payments
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Less: imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Undiscounted future operating lease payments
Undiscounted future operating lease payments
Regulatory approval milestone contingent payment
Regulatory Approval Milestone Contingent Payment
Regulatory approval milestone contingent payment.
Accounts receivable, Deductions
Decrease In Accounts Receivables
Decrease in accounts receivables.
Equity Components
Equity Components [Axis]
Summary of Transaction Price on Rewrite Merger Agreement Date Determined and Allocated
Schedule of Transaction Price Table Text Block
Schedule of Transaction Price Table Text Block
Equity Component
Equity Component [Domain]
Business Combination [Axis]
Utilities [Member]
Utilities [Member]
Utilities.
IPO [Member]
Initial Public Offering [Member]
Issuance of shares under employee stock purchase plan, shares
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Area of space leased
Area Of Space Leased
Area of space leased.
Maximum
Maximum [Member]
Maximum [Member]
Statistical Measurement
Statistical Measurement [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price per Share, Exercised
Common stock, $0.0001 par value; 240,000,000 shares authorized at Mrach 31, 2026 and December 31, 2025; 120,447,521 and 116,317,060 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
ONK therapeutics
ONK Therapeutics [Member]
Probability of achievement
Probability of achievement
Regeneron Pharmaceuticals Inc. [Member]
Regeneron Pharmaceuticals Inc [Member]
Regeneron Pharmaceuticals Inc.
Non-executive employees.
Non-executive Employees [Member]
Non-executive Employees [Member]
Marketable Securities [Line Items]
Marketable Securities [Line Items]
Regulatory approval milestone liability
Regulatory approval milestone liability
Regulatory approval milestone liability
Percentage of investment returned
Percentage of Investment Returned
Percentage of investment returned.
Other Nonoperating Income (Expense) [Abstract]
Other income, net:
Expected volatility of underlying stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Research milestone payments
Research milestone payments
Research milestone payments
Kyverna Therapeutics Inc.
Kyverna Therapeutics Inc [Member]
Kyverna Therapeutics Inc [Member]
Total operating expenses
Costs and Expenses
NonRule10b51ArrModifiedFlag
Non-Rule 10b5-1 Arrangement Modified
Non-Rule 10b5-1 Arrangement Modified
Business Combination [Table]
Entity Registrant Name
Entity Registrant Name
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Deferred revenue, Deductions
Contract with Customer, Liability, Change in Timeframe, Performance Obligation Satisfied, Revenue Recognized
Other Nonoperating Income (Expense)
Total other income, net
Projected year of achievement
Projected year of achievement
Rewrite Acquisition [Member]
Rewrite Acquisition [Member]
Rewrite Acquisition.
Subsequent Events [Abstract]
Consolidated Entities [Domain]
Measurement Frequency
Measurement Frequency [Axis]
Other Investments, Total
Other Investments
Other investments
Proceeds from common stock offering
Proceeds from Issuance of Common Stock
Net proceeds from issuance of common stock through at-the-market offerings
Business Combination, Contingent Consideration, Type [Axis]
Operating expenses:
Costs and Expenses [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Contingent Consideration Liability Research [Member]
Contingent Consideration Liability Research [Member]
Contingent Consideration Liability - research [Member]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Liability Class [Axis]
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income
Consolidation Items [Axis]
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Gain (Loss) on Investments
Change in fair value of investments
Change in fair value of investments, net
Change in fair value of investments, net
Number of Shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of share granted
Weighted Average Grant Date Fair Value per Share, Cancelled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Cancelled In Period Weighted Average Grant Date Fair Value
Share based compensation arrangement by share based payment award equity instruments other than options cancelled in period weighted average grant date fair value.
Assets
Total assets
Weighted Average Remaining Contractual Term, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Income Statement [Abstract]
Stock Issued During Period, Shares, New Issues
Number of stock additionally invested
Issuance of common stock, shares
Number of Shares, Vested
Additional vesting of shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of shares vested
Business Combination [Abstract]
Net loss per share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Fifth Floor Component [Member]
5th floor component.
Fifth Floor Component [Member]
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule Of Segment Reporting
Operating Segments [Member]
Operating Segments [Member]
Title and Position [Domain]
City Area Code
City Area Code
Business Combination [Line Items]
Counterparty Name
Counterparty Name [Domain]
Issuance of shares under employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Segment Reporting Information [Line Items]
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Total
Property and equipment, net
Property, Plant and Equipment, Net
Cash, cash equivalents and restricted cash equivalents, end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Total cash and cash equivalents and restricted cash equivalents
Cash, cash equivalents and restricted cash equivalents, beginning of period
Total cash, cash equivalents and restricted cash equivalents
Operating loss
Operating Income (Loss)
Accumulated Deficit [Member]
Retained Earnings [Member]
Accumulated Deficit
Business Combination, Contingent Consideration, Type [Domain]
Cash and Cash Equivalents [Axis]
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation
Performance stock units.
Performance Stock Units [Member]
PSUs [Member]
Initial Tech Square Premises [Member]
Initial tech square premises.
First Floor Component [Member]
1st floor component.
First Floor Component [Member]
Unrecorded Unconditional Purchase Obligation
Unrecorded Unconditional Purchase Obligation, Including Lease Not yet Commenced, Total
Unrecorded Unconditional Purchase Obligation, Total
Operating lease, modification payments
Statement of Financial Position Location, Activity, Capitalization [Domain]
Long-term operating lease liability
Operating Lease, Liability, Noncurrent
Operating Lease Liability Noncurrent, Total
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Class Of Stock [Line Items]
Class of Stock [Line Items]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Lease, Cost [Table Text Block]
Summary of Lease Costs and Other Information
Investments, Fair Value Disclosure
Investments, Fair Value Disclosure, Total
Total marketable securities
Fair value of investment
Summary of Available-for-sale Marketable Securities
Marketable Securities [Table Text Block]
2015 Plan [Member]
Two Thousand And Fifteen Stock Option And Incentive Plan [Member]
2015 Stock option and incentive plan.
Potential Dilutive Securities Excluded from Computation of Diluted Net Loss Per Common Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Corporate Debt Securities [Member]
Corporate Debt Securities [Member]
Entity Interactive Data Current
Entity Interactive Data Current
Additional Tech Square Premises [Member]
Additional Tech Square Premises [Member]
Additional tech square premises.
Deferred revenue
Increase (Decrease) in Contract with Customer, Liability
Income Statement Location
Statement of Income Location, Balance [Domain]
CASH FLOWS FROM OPERATING ACTIVITIES:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of investment discounts
Accretion of investment discounts and premiums
Common stock, shares issued in connection with research milestone
Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares
Segment Reporting Information, Revenue for Reportable Segment [Abstract]
Entity Tax Identification Number
Entity Tax Identification Number
Lonvo-Z [Member]
Lonvo-ZMember
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Overview and Basis of Presentation
Unrealized (loss) gain on marketable securities
Marketable Securities, Unrealized Gain (Loss), Total
Marketable Security, Unrealized Gain (Loss)
Unrealized gain on marketable securities
Local Phone Number
Local Phone Number
Unrecognized compensation cost related to stock options
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Investments in Affiliates, Subsidiaries, Associates, and Joint Ventures, Fair Value Disclosure
Investment in Kyverna Therapeutics, Inc.
Investment in Kyverna
Stock issuance cost, net
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Accounting Policies [Abstract]
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Collaboration revenue
Collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax
2030
Lessee, Operating Lease, Liability, to be Paid, Year Four
Accrued Expenses Related to Restructuring
Accrued expenses related to restructuring.
Accrued expenses related to restructuring
Weighted average period of unrecognized compensation costs
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Accrued legal and professional expenses
Accrued Professional Fees, Current
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company