| Schedule of Segment Reporting Information, by Segment |
The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):
| | | | | | | | | | | | | | | | | | | | | Three Months Ended March 31, | | | | | 2026 | | 2025 | | | | | Expenses | | | | | | | | | Manufacturing and process development | | $ | 23,208 | | | $ | 18,655 | | | | | | Clinical operations and development | | 14,570 | | | 10,026 | | | | | | Research and development personnel cost and other (including stock-based compensation) | | 9,121 | | | 5,096 | | | | | | Research | | 601 | | | 556 | | | | | | Total research and development | | 47,500 | | | 34,333 | | | | | | General and administrative personnel costs (including stock-based compensation) | | 7,963 | | | 4,832 | | | | | | Professional fees | | 3,560 | | | 1,504 | | | | | | Facility costs, IT, office expense and other | | 1,219 | | | 1,119 | | | | | | Total general and administrative expenses | | 12,742 | | | 7,455 | | | | | | Total operating expenses | | 60,242 | | | 41,788 | | | | | | Operating loss | | (60,242) | | | (41,788) | | | | | | Interest income | | 4,083 | | | 5,014 | | | | | | | | | | | | | | | Total other income | | 4,083 | | | 5,014 | | | | | | Net income before losses | | (56,159) | | | (36,774) | | | | | | Income tax expense | | (52) | | | (72) | | | | | | Segment and consolidated net loss | | $ | (56,211) | | | $ | (36,846) | | | | | |
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